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INSOMNIA and Simvastatin

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INSOMNIA Symptoms and Causes

Insomnia is a common sleep disorder. If you have it, you may have trouble falling asleep, staying asleep, or both. As a result, you may get too little sleep or have poor-quality sleep. You may not feel refreshed when you wake up.

Symptoms of Insomnia include:

  • Lying awake for a long time before you fall asleep
  • Sleeping for only short periods
  • Being awake for much of the night
  • Feeling as if you haven't slept at all
  • Waking up too early

Your doctor will diagnose Insomnia based on your medical and sleep histories and a physical exam. He or she also may recommend a sleep study. A sleep study measures how well you sleep and how your body responds to sleep problems. Treatments include good sleep habits, counseling, and medicines.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for INSOMNIA

INSOMNIA treatment research studies

Simvastatin clinical trials, surveys and public health registries


Find Drug Side Effect reports



Simvastatin Side Effects

Rhabdomyolysis (1168)
Myalgia (1039)
Renal Failure Acute (504)
Fatigue (491)
Blood Creatine Phosphokinase Increased (489)
Pain In Extremity (449)
Muscular Weakness (445)
Asthenia (394)
Arthralgia (375)
Muscle Spasms (346)
Pain (328)
Dyspnoea (311)
Dizziness (304)
Nausea (281)
Fall (261)
Diarrhoea (257)
Gait Disturbance (243)
Alanine Aminotransferase Increased (241)
Headache (240)
Myositis (238)
Malaise (187)
Myopathy (180)
Back Pain (166)
Amnesia (163)
Vomiting (160)
Insomnia (157)
Depression (156)
Rash (154)
Aspartate Aminotransferase Increased (152)
Renal Failure (143)
Liver Function Test Abnormal (141)
Abdominal Pain (140)
Chest Pain (134)
Blood Creatinine Increased (133)
Confusional State (130)
Paraesthesia (126)
Hypoaesthesia (126)
Feeling Abnormal (123)
Memory Impairment (122)
Anxiety (117)
Myocardial Infarction (112)
Weight Decreased (111)
Pruritus (107)
Cough (107)
Condition Aggravated (106)
Cerebrovascular Accident (104)
Tendon Rupture (103)
Hepatic Enzyme Increased (101)
Mobility Decreased (98)
Abasia (98)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I been on simastatin 20gms for 4 yrs. I remember I did had a rash last Aug 09 and it was realy itch. After 2 wks of suffering. I finally made Appt. with my Dr.. They schelule me for the following week. The day I planed t

:(vvery dissy imsoniac light headness.................. =-O

A few months ago my doctor prescribed 40mg simvastatin to take one before bedtime ,and he never told me anything about the side efect of thid drug,I have started feeling some muscle pain and abdomnel paint that was later on after I started taking the

Blurred vision, like I was looking through water around the outside of my eyes, then very dizz, faint but not fainting--this has happened twice, I was shaky and weak after--it was frightening.....

Extreme muscle pain in legs, shoulders, neck and back. already had fibromyalgia and this was worse than any pain had previous to taking simvastatin. I was on it a yr. I had chonic insomnia, chest pain like pneumonia, so tired couldn't hardly move. co

Hair loss

Has anyone taking this medication after a year,expierenced headaches?

Have been on Zocor for almost 10 years with no problems but 6 months ago started getting rash on my left side which seems to be less annoying with good skin lotion. I also take some vitamin pills that have 1000% niacin(for building good HDL) and Niac

I am taking 40 mg of simvaststin and my hair is really falling out bad. it stated this after i've been on the drug for awhile. should i stop taking it to see will my hair stop coming out from the root?

I can certainly sympathize. I began taking 40mg dose of Zocor inNovember of 2009 three days a week. Took for 6 months. Had blood work done in March. Cholesterol level dropped to 206. Doctor

Does anyone else have insomnia problems, with this drug, was fine before taking it, but now having major trouble getting to sleep and staying asleep.

<b>drowsy, insomnia, slight palpitation, nervousness</b>.

<span style='color: #808080;'>Took Diprophos for rheumatoid arthritis. Side effects: insomnia for 2 nights, perspiring during night, redness in face. Increased need to urinate.

<span style='visibility: visible;'><span style='visibility: visible;'>After battling with acute insomnia for about 3 months, my GP prescribed Trimipramine 25mg. This still didn't get me much sleep, so he prescribed Purata 30mg. Better, bu

2 patients given thiocolchicoside reported of muscular stiffness,uneasiness,insomnia,breathlessness and feeling of restlessness, 2 out of 5 patients have reported such experiences after consuming thiocolchicoside.i strongly recommend to withdraw this

2 weeks on it- terrible insomnia and blood pressure went from regular 120/62 to 130/80 Felt as if I were on Prednisone! Stopped drug.

31 years old female, I usesibutramina and feel overwhelmed, palpitations, thirsty all the time, insomnia, bad humor, headaches,an state of euphoria

After having the Clopixol depot I can't get an erection and have insomnia. It's a bad drug and I do not recommend it.

After taking Floxstat, I had nausea and vomiting along and insomnia for that period.

Agression Insomnia

INSOMNIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting New Clinical Applications for Internet-based Cognitive Behavior Therapy for Insomnia and Depression
Conditions: Insomnia;   Major Depression;   Minor Depression
Interventions: Behavioral: Therapist guided Internet-CBT for Insomnia w. extra support;   Behavioral: Therapist guided Internet-CBT for Insomnia;   Behavioral: Therapist guided Internet-CBT for Insomnia and depression;   Behavioral: Therapist Guided Internet-CBT for depression plus Insomnia placebo
Outcome Measures: Change (from baseline) in Insomnia Severity Index (ISI);   Change (from baseline) in Montgomery Asberg Depression Rating Scale, MADRS-S;   Change (from baseline) in Sleep Diary;   Changes (from baseline) in Actigraph data;   Change (from baseline) in Trimbos and Institute of Medical Technology Assessment Cost Questionnaire for Psychiatry (TIC-P);   Change (from baseline) in Cognitive functioning;   Change (from baseline) in EuroQuol. EQ-5D;   Change (from baseline) in Sheehan Disability Scale;   Change (from baseline) in Clinical Outcome in Routine Evaluation - 10, CORE-OM
2 Recruiting Behavioral Insomnia Therapy For Those With Insomnia and Depression
Conditions: Insomnia;   Major Depressive Disorder
Interventions: Drug: Escitalopram + CBT-I;   Behavioral: CBT-I plus placebo antidepressant medication;   Drug: Escitalopram
Outcome Measures: Mean two-week sleep log estimate of post-treatment sleep continuity;   Mean two-night polysomnographic post-treatment sleep continuity
3 Recruiting Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia
Condition: Insomnia
Interventions: Behavioral: In-person Cognitive Behavioral Therapy of Insomnia;   Behavioral: Internet Cognitive Behavioral Therapy of Insomnia
Outcome Measures: Sleep Diary;   Beck Depression Inventory II;   Substance use;   Actigraphy;   PTSD Check List-Military;   Beck Anxiety Inventory;   Insomnia Severity Index;   Epworth Sleepiness Scale;   Dysfunctional Beliefs and Attitudes About Sleep Scale;   Multidimensional Fatigue Inventory;   Veterans Rand 12-Item Health Survey
4 Recruiting Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors
Conditions: Anxiety Disorder;   Worry;   Uncertainty;   Sleep Disorders;   Insomnia;   Fatigue;   Pain;   Depression;   Cognitive-behavioral Therapy;   Psychological Intervention;   Esophageal Cancer;   Pancreatic Cancer;   Leukemia;   Lung Cancer;   Multiple Myeloma;   Ovarian Neoplasm;   Stage III or IV Cervical or Uterine Cancer;   Stage IIIB, IIIC, or IV Breast Cancer;   Glioblastoma Multiforme;   Relapsed Lymphoma;   Stage III or IV Colorectal Cancer;   Stage IIIC or IV Melanoma
Intervention: Behavioral: Cognitive-behavioral therapy for worry, uncertainty & Insomnia
Outcome Measures: Changes in worry on the Penn State Worry Questionnaire;   Changes in sleep efficiency on the Insomnia Severity Index;   Changes in intolerance of uncertainty on the Intolerance of Uncertainty Scale;   Levels of cortisol;   Levels of pro and anti-inflammatory cytokines;   Levels of myeloid-derived suppressor cells (MDSC)
5 Not yet recruiting A Behavioral Therapy for Insomnia Co-existing With COPD
Conditions: Insomnia;   COPD;   Chronic Obstructive Pulmonary Disease;   Fatigue
Interventions: Behavioral: Cognitive Behavioral Therapy for Insomnia;   Behavioral: COPD Education;   Behavioral: Attention Control
Outcome Measures: Insomnia;   Fatigue;   Beliefs about sleep;   Sleep habits;   Self-efficacy for sleep;   Self-efficacy for COPD management;   Emotional arousal;   Inflammation;   Pulmonary function;   Daytime functioning
6 Recruiting Group Treatment for Insomnia in Primary Health Care
Condition: Insomnia
Intervention: Behavioral: Group treatment for Insomnia
Outcome Measures: Insomnia severity Index;   Fatigue severity scale
7 Recruiting Stepped Care Model for the Wider Dissemination of Cognitive-Behavioural Therapy for Insomnia Among Cancer Patients : Efficacy and Cost-Effectiveness
Condition: Insomnia
Interventions: Behavioral: Professionally-administered cognitive-behavioral therapy for Insomnia (CBT-I);   Behavioral: Web-based cognitive-behavioral therapy for Insomnia (CBT-I)
Outcome Measures: Change in Insomnia Severity Index;   Change in sleep efficiency (SE) index (%);   Change in sleep onset latency (SOL) - from sleep diary;   Change in wake after sleep onset (WASO) - from sleep diary;   Change in total wake time (TWT) - from sleep diary;   Change in total sleep time (TST) - from sleep diary;   Change in hypnotic use - from sleep diary;   Change in sleep onset latency (SOL) - from actigraphy;   Change in wake after sleep onset (WASO) - from actigraphy;   Change in total wake time (TWT) - from actigraphy;   Change in total sleep time (TST) - from actigraphy;   Change in sleep efficiency (SE) index (%) - from actigraphy
8 Not yet recruiting Insomnia Treatment for Women Veterans
Condition: Insomnia
Interventions: Behavioral: Behavioral treatment for Insomnia-Group I;   Behavioral: Behavioral treatment for Insomnia-Group II
Outcome Measures: Adherence with behavioral treatment for Insomnia;   Sleep/wake patterns
9 Not yet recruiting Cognitive Behavioral Therapy for Insomnia and Nocturnal Hot Flashes in Menopause
Conditions: Menopause;   Insomnia;   Hot Flashes
Intervention: Behavioral: Cognitive Behavioral Therapy for Menopausal Insomnia (CBTMI)
Outcome Measures: Insomnia Severity Index (ISI);   Hot Flash Severity Diaries;   Menopause Quality of Life Scale total score
10 Unknown  A Treatment Study Comparing Two Non-Drug, Self-Help Treatment of Chronic Insomnia.
Condition: Insomnia
Interventions: Behavioral: Computerized delivery of cognitive-behavioral treatment of Insomnia;   Behavioral: Self-help manual to improve Insomnia symptoms
Outcome Measures: Changes in sleep parameters via polysomnography;   Changes in sleep parameters via self-reported sleep diary;   Changes in symptom severity as measured by Insomnia Severity Index;   Changes in symptom severity as measured by Pittsburgh Sleep Quality Index;   Changes in symptom severity as measured by the Multi-dimensional Fatigue Inventory;   Changes in depression symptoms as measured by Beck Depression Inventory II;   Changes in quality of life as measured by a qualitative instrument;   Usability of the device as measured by a qualitative questionnaire
11 Recruiting Treatment for Insomnia During Pregnancy
Condition: Sleep Initiation and Maintenance Disorders
Interventions: Behavioral: Arousal Based Therapy for Insomnia;   Behavioral: Cognitive Behavioral Therapy for Insomnia
Outcome Measures: Rate of Insomnia remission;   Insomnia severity;   Depression severity;   Sleep Characteristics
12 Recruiting The Effect of Family History on Insomnia During Sobriety in Alcoholics
Condition: Insomnia
Intervention: Behavioral: Cognitive Behavioral Therapy for Insomnia (CBT-I)
Outcome Measures: Insomnia Severity Index total score;   Time Line Follow Back measure
13 Unknown  Treatments for Insomnia in Patients With Parkinson's Disease
Conditions: Parkinson's Disease;   Insomnia
Interventions: Device: Light box (Litebook company);   Behavioral: CBT and sleep hygiene;   Drug: Doxepin and Zopiclone;   Device: Light box ( Litebook company)
Outcome Measures: SCOPA sleep scale;   Actigraphy;   Daily sleep dairy;   Insomnia severity Index (ISI);   Pittsburgh Sleep Quality Index (PSQI);   Parkinson's Disease Sleep Scale (PDSS);   Clinical global impression of change;   The Krupp Fatigue Severity Scale;   Beck depression index;   Adherence to treatment;   Severity of motor manifestations (UPDRS);   Quality of life (PDQ-39);   Adverse events;   Sleep Hygiene Index;   Dysfunctional Beliefs and Attitudes about Sleep, a brief version ( DBAS 16);   Epworth Sleepiness Scale (ESS)
14 Unknown  Acupuncture for the Treatment of Insomnia
Condition: Primary Insomnia
Intervention: Other: Acupuncture
Outcome Measures: Sleep efficiency on polysomnography;   Pittsburgh Sleep Quality Index (PSQI);   Insomnia Severity Index (ISI);   Epworth Sleepiness Scale (ESS);   Multidimensional Fatigue Inventory (MFI);   Inventory for Depressive Symptomatology—Self-Rated (IDS-SR);   State version of the Spielberger State-Trait Anxiety Inventory (STAI-s);   The Pre-Sleep Arousal Scale (PSAS);   Pittsburgh Sleep Diary (PghSD) and actigraphy recording;   Adverse event form (AEF);   Autonomic arousal as measured by HRV & Q-EEG during sleep recording
15 Recruiting Multidisciplinary Approach to the Treatment of Insomnia and Comorbid Sleep Apnea
Conditions: Obstructive Sleep Apnea;   Insomnia
Interventions: Behavioral: CBT-I;   Procedure: CPAP
Outcome Measures: CPAP adherence;   Pittsburgh Sleep Quality Index (PSQI);   Polysomnography (PSG);   Insomnia Severity Index (ISI);   Functional Outcomes of Sleep Questionnaire (FOSQ);   Actigraphy
16 Recruiting Sequenced Therapies for Comorbid and Primary Insomnias
Conditions: Insomnia Comorbid to Psychiatric Disorder;   Primary Insomnia
Interventions: Behavioral: Behavioral Insomnia Therapy;   Drug: Zolpidem;   Drug: Trazodone;   Behavioral: Cognitive Therapy
Outcome Measure: Insomnia Severity Index- Change from Baseline (Remission)
17 Recruiting Treatment of Insomnia and Depression in Elders (TIDE)
Conditions: Depression;   Insomnia
Interventions: Behavioral: Integrated Cognitive Behavioral Therapy (CBT);   Behavioral: Treatment as usual
Outcome Measures: Insomnia Severity Index;   Hamilton Depression Scale;   GDS;   SOL;   WASO
18 Not yet recruiting A High Density EEG Comparison of Sleep Patterns in Insomnia
Condition: Primary Insomnia
Intervention: Behavioral: Serial awakenings
Outcome Measures: Topographic sleep EEG power;   Topographic EEG power prior to nocturnal arousal;   Topographic EEG power during falling asleep period
19 Recruiting Internet-Based Cognitive-Behavioral Therapy for Insomnia
Condition: Insomnia
Intervention: Behavioral: Cognitive-Behavioral Therapy
Outcome Measures: Sleep parameters (sleep onset latency, sleep efficiency, total sleep time, times of wakening during sleep) changes from baseline to 5-week posttreatment by subjective measures using sleep log.;   Self-rated sleep quality score measured by the Pittsburgh Sleep Quality Index (PSQI) questionnaire;   Self-rated sleep-related cognition score measured by Dysfunctional Beliefs and Attitudes about Sleep Scale (DBAS);   Self-rated severity of depressive and anxiety symptoms measured by Hospital Anxiety and Depression Scale (HADS);   Subjects' general health and quality of life regarding physical functioning, social functioning, physical role limitations, emotional role limitations, mental health, vitality, bodily pain, and general health perception measured by Short form -36 (SF-36);   Self-rated fatigue score measured by Multidimensional Fatigue Inventory (MFI);   Subjects' acceptability and credibility to the treatment measured by Treatment acceptability and credibility rating scale;   Subjects' adherence to the treatment measured by Treatment adherence rating scale;   Subjects' satisfaction to the treatment measured by Treatment satisfaction rating scale;   Potential side effects associated with each component of CBT measured by Symptom checklist;   Self-rated sleep quality score changes from baseline to 12-week posttreatment measured by Insomnia Severity Index questionnaire
20 Recruiting Understanding the Sleep Apnea/Insomnia Interaction
Conditions: Sleep Apnea Syndromes;   Sleep Initiation and Maintenance Disorders
Interventions: Device: CPAP;   Behavioral: CBT;   Device: sham CPAP;   Behavioral: CC
Outcome Measure: Insomnia Severity Index Score