Rank |
Status |
Study |
1 |
Recruiting
|
Implementation of a Transcutaneous Bilirubinometer
Conditions: |
Neonatal Jaundice; Hyperbilirubinemia |
Interventions: |
Device: Transcutaneous Bilirubinometer; Other: visual assessment of neonatal Jaundice |
Outcome Measures: |
Number of blood tests for bilirubin measurement (Before the potential start of phototherapy).; Phototherapy duration in hours; Number of serum bilirubin-values above the 'exchange transfusion limit'; Highest measured serum bilirubin-value; Cost-effectiveness; Number of patients having kernicterus |
|
2 |
Recruiting
|
Immune Function in Patients With Obstructive Jaundice
Conditions: |
Obstructive Jaundice; Disease as Reason for ERCP; Immune Dysfunction; Immune Tolerance |
Intervention: |
|
Outcome Measures: |
Change in monocyte cytokine responses to endotoxin stimulation; Change in concentration of systemic quorum sensing signaling molecules |
|
3 |
Not yet recruiting
|
The Effect of Ursodeoxycholic Acid in Liver Functional Restoration of Patients With Obstructive Jaundice
Condition: |
Obstructive Jaundice |
Intervention: |
Drug: Ursodeoxycholic Acid |
Outcome Measures: |
Liver functional restoration; To assess that in which functional parameters of the liver, treatment with UDCA will have greater impact |
|
4 |
Recruiting
|
Treatment of Neonatal Jaundice With Filtered Sunlight Phototherapy: Safety and Efficacy in African Neonates
Condition: |
Jaundice, Neonatal |
Interventions: |
Procedure: Window tinting film for filtered sunlight phototherapy; Device: conventional phototherapy |
Outcome Measures: |
Change in Serum Bilirubin; Incidence of Sunburn and Dehydration; Non-inferiority of sunlight phototherapy; Number of participants requiring intervention such as exchange blood transfusion |
|
5 |
Unknown †
|
Randomised Trial Comparing Metal and Plastic Biliary Stents Stents for Palliating Malignant Jaundice
Condition: |
Biliary Obstruction |
Intervention: |
Device: SEMS |
Outcome Measures: |
Overall cost comparison of metal versus plastic stent in patients with limited life expectancy; Quality of life assessment |
|
6 |
Recruiting
|
Quality of Life After BDA or Stents to Treat Biliary Obstruction in Pancreas Cancer
Conditions: |
Local Tumor Spread; Advanced Cancer; Metastasized; Pancreatic Cancer Non-resectable; Jaundice |
Interventions: |
Procedure: Stent; Procedure: Biliodigestive anastomosis |
Outcome Measures: |
Outcome of Quality of Life.; The incidence of surgical complications and complications, with regard to the endo-scopic stent insertion, are further aspects that shall be examined in this study. |
|
7 |
Unknown †
|
Evaluation of Immune Function in Biliary Atresia Children With Prolonged Jaundice
Condition: |
Biliary Atresia |
Intervention: |
|
Outcome Measure: |
|
|
8 |
Recruiting
|
Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers
Conditions: |
Periampullary Cancers Causing Obstructive Jaundice; Pancreas Head Cancer; Bile Duct Cancer; Ampulla of Vater Cancer |
Intervention: |
Procedure: biliary drainage |
Outcome Measures: |
Incidence of infectious complications after biliary drainage; Effect of reducing serum total bilirubin after drainage; Peritumoral inflammatory reaction after drainage; Fibrosis of the bile duct; Difficulties in dissection around the tumor |
|
9 |
Recruiting
|
Study Evaluating the Safety and Efficacy of Two Doses of Stannsoporfin in Combination With Phototherapy in Neonates With Hyperbilirubinemia
Conditions: |
Jaundice, Neonatal; Hyperbilirubinemia, Neonatal |
Interventions: |
Drug: stannsoporfin; Drug: Placebo |
Outcome Measures: |
Percent change from baseline in total serum bilirubin (TSB) (the baseline TSB is the TSB that qualifies for randomization) at 48 hours post-dose; Percent change from baseline in TSB (the baseline TSB is the TSB that qualifies for randomization) at 6, 12, 24, and 36 hours; Total serum bilirubin area under the curve (AUC) above the baseline TSB (0 to 48 hours post-dose).; Peak serum bilirubin; Incidence of rebound hyperbilirubinemia defined as an increase in TSB above the age-specific threshold for initiating PT per the AAP Guidelines (AAP) following the discontinuation of the initial PT; Incidence of readmission to hospital for hyperbilirubinemia due to a TSB at or above the age specific threshold for PT; Duration of clinical requirement for PT; Incidence of adverse events (AE) and serious adverse events (SAE's); Changes in vital sign measurements; Results of physical exam (PE), including growth measurements; Results of neurologic exam, including eye and hearing assessment; Electrocardiographic (ECG) assessments; Clinical laboratory tests including hematology, serum chemistries, liver function and renal function tests |
|
10 |
Unknown †
|
Measurement of Carboxyhemoglobin by Gas Chromatography as an Index of Hemolysis
Conditions: |
ABO Incompatibility; Hemolytic Disease of Newborn; Neonatal Jaundice; Neonatal Hyperbilirubinemia |
Intervention: |
|
Outcome Measure: |
|
|
11 |
Recruiting
|
Comparison of Metal and Plastic Stents for Preoperative Biliary Decompression
Conditions: |
Obstructive Jaundice; Pancreatic Cancer |
Interventions: |
Procedure: Metal stent placement in the bile duct; Procedure: Plastic stent |
Outcome Measures: |
Complications related to stent dysfunction; Procedural complications |
|
12 |
Recruiting
|
Prospective Randomized Study of PTC and EUS-guided Drainage of the Bile Duct
Condition: |
Jaundice |
Interventions: |
Device: biliary drainage; Device: EUS guided biliary drainage |
Outcome Measures: |
Morbidity rate; efficacy; feasibility; biliary drainage duration; quality of life |
|
13 |
Available
|
Compassionate Use of Stanate (TM) [Stannsoporfin]
Conditions: |
Neonatal Jaundice; Hyperbilirubinemia |
Intervention: |
Drug: Stanate (TM) [stannsoporfin, tin-mesoporphyrin] |
Outcome Measure: |
|
|
14 |
Recruiting
|
Neuroprotection With Statin Therapy for Acute Recovery Trial Phase 2
Conditions: |
Stroke; Rhabdomyolysis; Jaundice |
Interventions: |
Drug: Lovastatin; Other: Placebo |
Outcome Measures: |
Increase in Liver Function Tests (LFTs); Increase in Creatine Kinase (CK); Score on NIH Stroke Scale; Barthel Index Score; Modified Rankin scores |
|
15 |
Recruiting
|
ComVi Stent Versus Uncovered Self-Expandable Metal Stent (SEMS) for Biliary SEMS Occlusion
Conditions: |
Biliary Tract Neoplasms; Jaundice, Obstructive |
Interventions: |
Device: ComVi stent; Device: Uncovered SEMS |
Outcome Measure: |
Time to stent occlusion |
|
16 |
Unknown †
|
Acute Viral Hepatitis and Diabetes Mellitus
Conditions: |
Acute Viral Hepatitis; Diabetes Mellitus |
Intervention: |
|
Outcome Measures: |
Duration of icteric hepatitis.; Development of complications; Mortality |
|
17 |
Recruiting
|
Comparison Between Endoscopic Stenting and Cholecystojejunostomy for PreoperativeDrainage Before Pancreaticoduodenectomy
Conditions: |
Periampullary Cancer; Pancreatic Cancer |
Interventions: |
Procedure: Endoscopic stenting; Procedure: cholecystojejunostomy |
Outcome Measures: |
Technical success; Successful drainage; Procedure-related complication: was defined complications directly related to stent insertion/CJ; Intraoperative assessment; 1. Procedure-related mortality; 2. Duration of hospital stay; 3. Postoperative complication:; a. Wound infection; b. Intra-abdominal abscess; c. Postoperative haemorrhage; d. Pancreaticojejunal leak; e. Bile leak |
|
18 |
Unknown †
|
Comparison Between Two Methods of Bilateral Stenting for Malignant Hilar Obstruction
Conditions: |
Bile Duct Neoplasm; Obstructive Jaundice |
Interventions: |
Procedure: parallel stent; Device: Y-stent (BONASTENT M-Hilar) |
Outcome Measure: |
The time taken to insert bilateral stent |
|
19 |
Recruiting
|
Trial Comparing Metal Versus Plastic Stents for Preoperative Biliary Decompression
Conditions: |
Obstructive Jaundice; Pancreatic Cancer |
Interventions: |
Procedure: Stent Dysfunction; Procedure: Complications |
Outcome Measures: |
Complications related to stent dysfunction; Procedural complications |
|
20 |
Unknown †
|
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Conditions: |
Respiratory Distress; Hypoglycemia; Feeding Intolerance; Jaundice; Hypothermia; Developmental Delay |
Intervention: |
|
Outcome Measure: |
neurodevelopmental, health and growth status in late preterm infants vs. controls within the first year of life |
|