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JOINT SWELLING and ACYCLOVIR

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JOINT SWELLING Symptoms and Causes

A joint is where two or more bones come together, like the knee, hip, elbow, or shoulder. Joints can be damaged by many types of injuries or diseases, including

  • Arthritis - inflammation of a joint. It causes pain, stiffness, and swelling. Over time, the joint can become severely damaged.
  • Bursitis - inflammation of a fluid-filled sac that cushions the joint
  • Dislocations - injuries that force the ends of the bones out of position

Treatment of joint problems depends on the cause. If you have a sports injury, treatment often begins with the RICE (Rest, Ice, Compression, and Elevation) method to relieve pain, reduce swelling, and speed healing. Other possible treatments include pain relievers, keeping the injured area from moving, rehabilitation, and sometimes surgery. For arthritis, injuries, or other diseases, you may need joint replacement surgery to remove the damaged joint and put in a new one.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for JOINT SWELLING

JOINT SWELLING treatment research studies

ACYCLOVIR clinical trials, surveys and public health registries


Find Drug Side Effect reports



ACYCLOVIR Side Effects

Renal Failure Acute (111)
Nausea (55)
Confusional State (53)
Neurotoxicity (52)
Blood Creatinine Increased (51)
Pyrexia (48)
Hallucination, Visual (38)
Herpes Zoster (38)
Vomiting (37)
Pain (37)
Fatigue (36)
Somnolence (36)
Renal Failure (35)
Diarrhoea (34)
Agitation (31)
Rash (31)
Renal Impairment (30)
Dyspnoea (30)
Haemodialysis (28)
Neutropenia (28)
Malaise (27)
Encephalopathy (27)
Febrile Neutropenia (27)
Dysarthria (26)
Hallucination (26)
Platelet Count Decreased (26)
Nephropathy Toxic (26)
Back Pain (24)
Alanine Aminotransferase Increased (23)
Insomnia (23)
Abdominal Pain (23)
Headache (22)
White Blood Cell Count Decreased (22)
Aphasia (22)
Pruritus (21)
Disorientation (20)
Hypertension (19)
Dizziness (19)
Pancytopenia (19)
Abdominal Pain Upper (19)
Coma (19)
Paraesthesia (19)
Pneumonia (18)
Sepsis (18)
Blood Pressure Increased (18)
Hepatotoxicity (17)
Anaemia (17)
Ataxia (17)
Hypotension (17)
Multi-organ Failure (17)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

Arthritis Treatment Safe, Natural Cure for Adults. Synflex Liquid Glucosamine, Rheumatoid Arthritis Joint Pain Relief Remedy, Diet Supplements. Synflex, Glucosamine for Dogs. Free Shipping! <a href='http://www.healthyjointcare.com/'&g

48 years of age. I was diagnosed with urinary tract infection. Had one dose of monuril 3 gr. After 7 hours developed skin rash on the back, arms and neck, generally swelling of the face, specially below the eyes, Had oral antihistamine and went to

Blurred vision, giddiness,Tiredness,Swelling on feet and hands

I have been Pradaxa for almost a month had severe outbreak of hives on my feet and my legs up to my knees. I also having swelling of legs and feet along with fatigue in joints and body limbs. Doctor changed my Med. but the side effects is still o

Can this medicine cause terrible joint pain --hips & knees & ankles

Intersting on the Bicor . i have been on it since march this year , starting with 2.5 , then to 5.0 , 7.5 and 10mg for the last 3 months . always felt tired in the increse dosage as advised . but now have had a fe w joint aches , chest pains and cur

Unresponsive to 5mg/kg q 8wks; increased to 10mg/kg q6wks. After 3 doses at that strength noted fatigue, occasional night sweats, joint aches, sudden onset of chest pain and dyspnea (pleurisy, small pleuraleffusion) Had just taper

Hey Michelle, we almost have the same issue..I switched from Yaz to Trinessa because I and my husband thought it caused my severe mood swings prior to my period. I have been running and working out but I start experiencing joint

<span style='color: #808080;'><b>Describe Your Injection site swelling from INFLUENZA (H1N1) (H1N1 (MONOVALENT) (UNKNOWN)) 2010 Experience Here: I am 46, Female on discharge from hospital 12.6.10 10pm after treatment for acute diverticuli

<span style='color: #808080;'>I just had 5 days of one venofir infusion a day.My hands and arms swelled up like balloons. They are very painful and feel like they are on fire. Ice packs helped the burning sensation but the swelling is still ver

JOINT SWELLING Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Effect of Body Mass on Acyclovir Pharmacokinetics
Conditions: Hematological Malignancy;   Pharmacokinetics of Acyclovir
Intervention:
Outcome Measures: Systemic clearance of Acyclovir in obese and non-obese patients;   Alpha and beta half-life of Acyclovir in obese and non-obese patients;   Maximum concentration (Cmax) of Acyclovir in obese and non-obese patients;   Time to maximum concentration (Tmax) of Acyclovir in obese and non-obese patients;   Volume of distribution (Vd and Vdss) of Acyclovir in obese and non-obese patients;   Time that concentration is above IC50 for varicella and herpes viruses 4,5,6,7 for Acyclovir in obese and non-obese patients
2 Recruiting Efficacy of Antiviral Medications in Controlling Vertigo Attacks of Patients With Meniere's Disease
Condition: Meniere's Disease
Interventions: Drug: Acyclovir;   Drug: Placebo
Outcome Measures: Vertigo;   Hearing Loss;   Aural Fullness;   Tinnitus
3 Recruiting Efficacy of Oral Famciclovir Versus Aciclovir Treatment in Patients With Herpes Zoster
Condition: Herpes Zoster
Interventions: Drug: Famciclovir;   Drug: Aciclovir
Outcome Measures: For efficacy evaluation, a visual analogue scale (VAS) will be used to detect the improvement of symptoms;   Safety will be evaluated by the adverse events occurrences
4 Recruiting Efficacy of Oral Famciclovir 125mg Comparing to Aciclovir 200 mg Treatment in Patients With Active Recurrent Genital Herpes
Condition: GENITAL HERPES
Interventions: Drug: Famciclovir;   Drug: Aciclovir
Outcome Measures: Efficacy will be evaluated by the proportion of subjects with non herpes manifestation;   Safety will be evaluated by the Adverse events occurence
5 Recruiting PTH - Preemptive Treatment for Herpesviridae
Condition: Viral Pneumonia
Interventions: Drug: Aciclovir;   Drug: Ganciclovir;   Drug: Placebo
Outcome Measures: Ventilator-free days at Day 60;   Day 60 mortality;   ICU mortality;   Hospital mortality;   Duration of mechanical ventilation in survivors;   Duration of ICU stay;   Duration of hospital stay;   Incidence of ventilator-associated pneumonia;   Incidence of bacteremia;   SOFA score;   Acute renal failure related to aciclovir or its placebo;   Leucopenia related to ganciclovir or its placebo;   Time to oropharyngeal negativation of HSV PCR;   Time to blood negativation of CMV PCR;   Incidence of herpetic bronchopneumonia;   Incidence of active CMV infection
6 Not yet recruiting A Study to Compare Two Techniques for Articular Cartilage Repair:ACIC Vs. MCIC
Condition: Articular Cartilage Defect
Interventions: Procedure: ACIC;   Procedure: MCIC;   Device: implant with a collagen + fibrin gel mixture
Outcome Measures: Clinical outcome;   Radiological outcome
7 Recruiting Contribution of Salivary Cortisol in the Detection of Infra-clinic Cortisol Adenoma (ACIC)
Condition: Obesity
Intervention: Other: Salivary Cortisol
Outcome Measures: Number of patients with positive salivary cortisol dosage among patients with positive serum cortisol dosage;   Number of patients with negative salivary cortisol dosage among patients with negative serum cortisol dosage;   Comparing the results of salivary cortisol dosage and serum cortisol dosage;   Comparing the results of the two salivary samples;   Number of patients with metabolic complications of obesity among patients with ACIC;   Number of patients with severe type 2 diabetes among patients with ACIC
8 Not yet recruiting Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection in Patients With Herpes Zoster
Condition: Herpes Zoster
Interventions: Drug: Foscarnet Sodium;   Drug: Acyclovir
Outcome Measures: Effective rate;   Incidence of Postherpetic neuralgia;   number of participants with adverse event and serious adverse event
9 Recruiting Cytomegalovirus Control in Critical Care
Condition: Critical Illness
Interventions: Drug: Valaciclovir/Aciclovir;   Drug: Valganciclovir/Ganciclovir
Outcome Measures: Time to reactivation of cytomegalovirus (CMV) polymerase chain reaction (PCR) (defined as above the lower limit of sample assay).;   Time to reactivation above the lower limit of assay detection of CMV PCR in urine, throat swab and non-directed bronchiolar lavage (NDBL). NDBL whilst trachea is intubated only.;   Time to >1000 CMV copies in blood, urine, throat swab and NDBL (NDBL whilst intubated);   Time to >10000 CMV copies in blood, urine, throat swab and NDBL (NDBL whilst intubated);   CMV PCR in blood, urine, throat swab and NDBL (NDBL whilst intubated);   Markers of inflammation;   Clinical Outcomes;   Number of Serious Adverse events;   Time to neutropenia (count <1.0x10-9/L);   Time to thrombocytopenia (platelet <50x10-9/L);   Use of G-CSF or termination of study drug;   Number of platelet transfusions received;   Time to renal insufficiency (CrCl <60ml/min, <30ml/min, need for renal support)
10 Unknown  Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System
Condition: Herpes Simplex
Intervention: Drug: Acyclovir
Outcome Measure:
11 Unknown  Comparison of Topical Antiviral Agents for Labial Cold Sores (Herpes Labialis)
Condition: Reccurent Herpes Labialis
Interventions: Drug: Acyclovir 5%;   Drug: Docosanol 10%;   Device: Superlysine gel
Outcome Measure: Reducing healing process and duration of cold sores using superlysin gel
12 Recruiting Bortezomib in KRAS-Mutant Non-Small Cell Lung Cancer in Never Smokers or Those With KRAS G12D
Condition: Non-Small Cell Lung Cancer
Interventions: Drug: Bortezomib;   Drug: Acyclovir
Outcome Measures: efficacy of single-agent subcutaneous bortezomib;   Efficacy;   Toxicity
13 Recruiting Phase 2 Trial of Carfilzomib for Metastatic Castration-resistant Prostate Cancer Following Treatment
Condition: Metastatic Castration-resistant Prostate Cancer
Interventions: Drug: Carfilzomib;   Drug: Dexamethasone;   Drug: Acyclovir
Outcome Measures: Progression-free survival (PFS);   Prostate-Specific Antigen (PSA) changes;   Circulating Tumor Cell (CTC) enumeration;   Baseline whole blood 20S proteasome level;   Measurable disease response rate;   Pain response;   Overall survival;   Assessment of toxicities
14 Not yet recruiting A Multiple Ascending Dose-Finding Pharmacokinetic and Pharmacodynamic Study of a Novel Antiviral Drug in Infants With Neonatal Herpes Simplex Virus (HSV)
Condition: Herpes Simplex Virus
Interventions: Drug: Novel Antiviral Drug;   Drug: Placebo
Outcome Measures: Plasma pharmacokinetic parameters for a Novel Antiviral Drug, including AUC24, maximum serum concentration (Cmax), half-life (T1/2), CL/F, and time to maximum concentration (Tmax);   Clearance of HSV DNA from CSF by Day 4 of antiviral treatment of neonatal HSV disease;   The incidence of SAEs and AEs considered to be related to study treatment;   The incidence of grade 3-4 AEs and SAEs, with or without relationship to study treatment;   Intracellular pharmacokinetic parameters for the active diphosphate moiety of a Novel Antiviral Drug in peripheral blood mononuclear cells (PBMCs);   Correlation of a Novel Antiviral Drug plasma and intracellular concentrations with qualitative and quantitative HSV detection in cerebrospinal fluid and blood by PCR
15 Unknown  Can ValAcyclovir Attenuate Inflammation in Antiretroviral-Treated HIV-Infected Individuals With Herpes Simplex Virus Type 2?
Conditions: HIV Infections;   Herpes Simplex
Interventions: Drug: ValAcyclovir;   Drug: Placebo
Outcome Measures: Percentage activated CD8+ T-cells;   Inflammatory markers;   CD4 cell count;   Virologic blips;   Drug-related adverse events;   HSV reactivations;   Acyclovir-resistant HSV
16 Recruiting Can ValAcyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals With Herpes Simplex Virus Type 2?
Conditions: HIV Infection;   Herpesvirus 2, Human;   HIV Infections
Interventions: Drug: valAcyclovir;   Drug: Placebo
Outcome Measures: Time from baseline until reaching the primary endpoint, a composite of either a CD4 cell count ≤350 cells/mm3 measured on two consecutive occasions at least 1 month apart, or initiation of HAART for any reason, whichever occurs first.;   Annual rate of change in CD4 count, calculated as the slope of patients' CD4 count change / time;   Annual rate of change in the CD4 cell count percentage, calculated as the slope of the patient's CD4 count percentage change over time;   Log10 plasma HIV viral load;   Treatment-emergent adverse events and laboratory abnormalities;   Frequency of episodes of HSV reactivations at any anatomic site;   Proportion of microbiologically confirmed flares of HSV during the trial that are caused by laboratory-confirmed Acyclovir-resistant HSV;   Quality of life
17 Not yet recruiting PACT for Individuals With Serious Mental Illness
Condition: Schizophrenia and Disorders With Psychotic Feature
Intervention: Other: Patient Aligned Care Team (PACT)
Outcome Measures: Composite Prevention Score;   Composite Diabetes Mellitus Score;   medical and mental health treatment utilization and cost;   Assess acceptability of the SMI-PACT model, and barriers and facilitators to its implementation;   Investigate the relationships between organizational context, intervention factors, and patient and provider outcomes;   Identify factors related to successful patient outcomes;   VA Decision Support System National Database Extracts (DSS NDEs);   Assessment of Chronic Illness Care (ACIC);   patient Assessment of Chronic Illness Care (PACIC);   Rogers' Adoption Questionnaire;   Maslach Burnout Inventory (MBI);   Behavior and Symptom Identification Scale - Revised (BASIS-R);   Ambulatory Care Experiences Survey (ACES; Short Form);   Interpersonal Support Evaluation List (ISEL);   Medication Possession Ratio (MPR);   Ethnographic field notes;   Semi-structured qualitative interviews
18 Recruiting Short Course of Bortezomib in Anemic Patients With Refractory Cold Agglutinin Disease
Condition: Refractory Cold Agglutinin Disease
Intervention: Drug: Bortezomib
Outcome Measures: Number of patients who become transfusion-free after Bortezomib therapy.;   Number of patients who have never been transfused with a >2g hemoglobin rise compared to baseline.;   Number of CTC grade 3 and 4 adverse events.;   Duration in months of transfusion independence.;   Effect of treatment on the underlying clonal B cell disorder.
19 Unknown  Early Response-adapted Intensification of Induction Chemotherapy in Patients With Newly Diagnosed Multiple Myeloma (MM)
Condition: Multiple Myeloma
Intervention: Drug: Thalidomide, cyclophosphamide, dexamethasone, bortezomib
Outcome Measure: response rate for induction chemotherapy
20 Recruiting HSV-tk + ValAcyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
Condition: Prostatic Neoplasms
Intervention: Drug: HSV-tk +ValAcyclovir in Combination with Brachytherapy
Outcome Measures: 1. Safety based on standard laboratory and clinical adverse event monitoring;   Local control survival (measured by PSA and biopsy);   Evaluate immunological markers