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MUSCLE SPASMS and Metoprolol

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MUSCLE SPASMS Symptoms and Causes

Angina is chest pain or discomfort you feel when there is not enough blood flow to your heart muscle. Your heart muscle needs the oxygen that the blood carries. Angina may feel like pressure or a squeezing pain in your chest. It may feel like indigestion. You may also feel pain in your shoulders, arms, neck, jaw, or back.

Angina is a symptom of coronary artery disease (CAD), the most common heart disease. CAD happens when a sticky substance called plaque builds up in the arteries that supply blood to the heart, reducing blood flow.

There are three types of angina:

  • Stable angina is the most common type. It happens when the heart is working harder than usual. Stable angina has a regular pattern. Rest and medicines usually help.
  • Unstable angina is the most dangerous. It does not follow a pattern and can happen without physical exertion. It does not go away with rest or medicine. It is a sign that you could have a heart attack soon.
  • Variant angina is rare. It happens when you are resting. Medicines can help.

Not all chest pain or discomfort is angina. If you have chest pain, you should see your health care provider.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for MUSCLE SPASMS

MUSCLE SPASMS treatment research studies

Metoprolol clinical trials, surveys and public health registries


Find Drug Side Effect reports



Metoprolol Side Effects

Bradycardia (409)
Dizziness (389)
Hypotension (291)
Blood Pressure Increased (282)
Dyspnoea (271)
Fatigue (258)
Completed Suicide (244)
Syncope (220)
Nausea (194)
Headache (187)
Chest Pain (166)
Palpitations (160)
Asthenia (152)
Diarrhoea (151)
Atrial Fibrillation (147)
Hypertension (145)
Pain (140)
Heart Rate Increased (131)
Anxiety (131)
Myocardial Infarction (129)
Fall (115)
Pain In Extremity (111)
Malaise (110)
Toxicity To Various Agents (104)
Oedema Peripheral (102)
Pruritus (101)
Product Substitution Issue (101)
Product Quality Issue (99)
Heart Rate Decreased (96)
Insomnia (96)
Cerebrovascular Accident (96)
Cardiac Arrest (89)
Rash (89)
Vomiting (87)
Feeling Abnormal (86)
Renal Failure (83)
Renal Failure Acute (83)
Depression (83)
Confusional State (78)
Blood Pressure Decreased (77)
Arthralgia (76)
Death (73)
Chest Discomfort (73)
Tachycardia (71)
Loss Of Consciousness (69)
Somnolence (69)
Hyperhidrosis (65)
Cardiogenic Shock (63)
Condition Aggravated (63)
Weight Decreased (62)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

<strong>I was put on Metoprolol ER 2 years ago after having cancer. I was </strong><span style='text-decoration: underline;'>tired all day could not sleep at night, had anxiety attacks, co

I have been taking Toprol XL 100 for 7 yrs with no issues or changes in my EKGs. I was switched to the Generic Metoprolol 50mg twice a day 3 months ago. I started experiencing PVCs and stomach trouble. Went to the ER twice becaus

i've been on the generic metoprolol for 3 days. dr. started me on 25mg 2x per day and i've been experiencing shortness of breath, chest discomfort and dizziness. i cut the dosage down to 6.5mg per day and feel a little better (palpations&

<strong>Tired all the time. Sleep poorly. Dry hacking cough and I am cold all the time. I can't seem to keep warm. I doubleup on my clothing and socks.</strong> <strong>Honestly, I have never

Calf twitches

Calfs constly twitching

Can i take Acetaminophen W/Codeine #3 with Metoprolol er succinate 25 mg ?

Does anyone have a nagging cough while taking metaprolol?

Does it hurt in your legs real bad, you can't sleep and your chest hurts? See your Doctor.

EVERYONE SHOULD TAKE NATURAL HERBS ITS GODS MEDICINE FOR EVERYBODY IT MAKES YOU WELL ;;ALL PERSRIPTION DRUGS IS NUMBER 1 KILLER IN THE WORLD .

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

muscle cramping when in a dead sleep

I just had the infusion two days ago (1/19/10) and was surprised with the intensity of muscle pain the day after the treatment. My pain was localized to my rib cage, neck, shoulders and upper back. In addition I was very fatiqued...slept most of

I started taking this medicine geodon 40 mg once a day. Then i notice i was blinking a lot. Then i started having eye muscle spasms several times a day.Now i have to go to the eye dr.I stop taking the medicine. Til I see what the dr.says.

I was having frequent leg cramps. They worked their way from my foot up to my thigh. I just thought it was from stopping the use of muscle relaxers ( for a serious back and neck problem). I had forgotten about them and never mentioned it to either

I am having cramps, muscle pain, memory loss, I have been on Revlmid for about 1 year. Does anybody else my age have this disease, I am only 46 yr woman.

one 10 mg pill cuased presure in thechest bad muslespasms in the back think past doses has sent me skizzo

<b>Describe Your Pravastatin Experience Here:</b> I have been on 20 mg since Jan. And have been having muscle pain in the back of the thighs? Has anyone felt muscle pain in that area. Don't know if it is from medication or exercise

I received an injection close to my shoulder blade June 16, 2010. Three months later, I have an indentation and my health care provider has indicated that perhaps the muscle has scare tissue and the indentation and disc

<span style='color: #808080;'><b>I experienced severe neck spasms the day after receiving my second shot of Gardasil. It's been 2 days with no releif. The doctor did not inform me of the side effects in fact she said '

MUSCLE SPASMS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Comparative Effects of Nebivolol and Metoprolol on Femal Sexual Function
Conditions: Hypertension;   Female Sexual Dysfunction
Interventions: Drug: nebivolol and Metoprolol succinate;   Drug: Metoprolol succinate and nebivolol
Outcome Measures: Change in FSF and CSFQ, two validated questionnaires for assessment of sexual function.;   The effects of nebivolol and Metoprolol on sexual function and to compare the effects of both drugs on vitality, work and life performance, and work and life satisfaction.
2 Recruiting Influence of CPB and Mini CPB to the Absorption of the Metoprolol
Condition: Drug Absorption
Intervention: Drug: blood concentration of Metoprolol
Outcome Measures: absorbtion of the Metoprolol;   atrial fibrillation
3 Not yet recruiting A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants
Condition: Healthy
Interventions: Drug: Metoprolol tartrate immediate-release (Metoprolol IR);   Drug: JNJ-54452840;   Drug: Placebo
Outcome Measures: Exercise Heart Rate;   Exercise Blood Pressure
4 Recruiting Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control
Conditions: Atrial Fibrillation;   Atrial Flutter
Interventions: Drug: Metoprolol;   Drug: Diltiazem
Outcome Measures: Conversion to sinus rhythm;   Heart rate control;   Home discharges from Emergency Department (ED);   Total hospital cost;   Rehospitalization for Atrial Fibrillation
5 Not yet recruiting Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects
Condition: Vasovagal Syncope
Interventions: Drug: Metoprolol;   Drug: Matching Placebo
Outcome Measures: The primary outcome measure will be the proportion of patients having at least one syncope recurrence.;   A secondary outcome will be the time between the first and second syncope recurrences.;   A secondary outcome will be the frequency of syncopal spells.;   A secondary outcome is the number, duration, and severity of presyncopal spells (as measured with the Calgary Presyncope Scale);   A secondary outcomes will be quality of life as measured by the EQ-5D and the ISQL.
6 Not yet recruiting Comparison of Efficacy of Ivabradine Versus Metoprolol
Condition: Coronary Artery Disease
Intervention: Drug: Ivabradine and Metoprolol
Outcome Measures: Heart rate of patient before CT coronary;   safety and side effect of Metoprolol and Ivabradine
7 Recruiting Genetically Targeted Therapy for the Prevention of Symptomatic Atrial Fibrillation in Patients With Heart Failure
Conditions: Atrial Fibrillation;   Atrial Flutter
Interventions: Drug: bucindolol hydrochloride;   Drug: Metoprolol succinate
Outcome Measures: Time to first event of symptomatic atrial fibrillation/atrial flutter (AF/AFL) or all cause mortality (ACM) during the 24-week Follow-up Period after conversion to stable sinus rhythm (SR);   Time to first event of AF/AFL (i.e., symptomatic or asymptomatic) or ACM during the 24-week Follow-up Period;   Proportion of patients during the 24-week Follow-up Period with ventricular tachycardia (VT), ventricular fibrillation (VF), or symptomatic supraventricular tachycardia (SVT);   Total number of hospitalization (all-cause) days per patient during the Total Study Period;   Time to first event of ACM or heart failure (HF) hospitalization (as assessed by the Investigator) during the Total Study Period;   Proportion of patients who have AF on ECG at the end of the study who demonstrate ventricular response rate (VRR) control
8 Recruiting A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement
Condition: Myocardial Ischemia
Interventions: Drug: Metoprolol;   Drug: Esmolol;   Drug: Placebo
Outcome Measures: Our objective is to clarify if Metoprolol, in a dose range used for perioperative cardiac protection, decreases anesthetic requirement.;   Administration of esmolol, a short-acting beta-receptor antagonist, might reduce the actual anesthetic requirement.
9 Recruiting Metoprolol Succinate in Cardiac Remodeling Related to Cirrhosis
Conditions: Cirrhosis;   Cirrhotic Cardiomyopathy;   Cardiac Remodeling
Interventions: Drug: Metoprolol succinate;   Drug: placebo
Outcome Measures: Improvement of systolic function;   Improvement in left ventricular diastolic function;   Renal function;   Serum level of BNP, catecholamines, plasmatic renin activity;   Mortality;   Quality of life;   Electrophysiologic modifications
10 Unknown  Metoprolol and Formoterol in Chronic Obstructive Pulmonary Disease (COPD)
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Intervention: Drug: Metoprolol
Outcome Measures: Difference in airway reactivity after treatment with Metoprolol compared to placebo.;   Effect of formoterol on airway reactivity comparing Metoprolol with placebo.;   Borg-scores during provocation test;   Peak-flow measurements;   CCQ-scores;   Exacerbation rate and rescue medication use
11 Recruiting Sarpogrelate Drug Interaction
Conditions: Hypertension;   Peripheral Artery Disease
Interventions: Drug: Sarpogrelate pretreatment;   Drug: Sarpogrelate;   Drug: Metoprolol
Outcome Measures: Plasma concentration of Metoprolol and metabolites;   Blood pressure and pulse rate changes
12 Recruiting Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure
Conditions: Peripheral Artery Disease;   Hypertension
Interventions: Drug: nebivolol;   Drug: Metoprolol succinate
Outcome Measures: Peak Walking Time;   Walking Impairment Questionnaire;   Ankle-brachial index;   markers of inflammation.;   Claudication Onset Time
13 Recruiting Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
Condition: Hypertension
Interventions: Drug: Metoprolol succinate;   Drug: Nebivolol;   Drug: Hydrochlorothiazide;   Drug: DEFINITY®;   Procedure: Non-invasive measurement of Cardiac Output (CO);   Procedure: Flow mediated vasodilation;   Procedure: Endothelial cell collection;   Procedure: Microvascular perfusion assessment using Definity
Outcome Measures: Endothelial cell protein expression;   Microvascular blood flow;   Flow mediated dilation (FMD)
14 Recruiting PREvention of Atrial Fibrillation in patientS Undergoing thorAcic surGEry for Lung Cancer
Conditions: Lung Cancer;   Atrial Fibrillation
Interventions: Drug: Metoprolol;   Drug: Losartan
Outcome Measures: Incidence of postoperative atrial fibrillation;   Evaluation of NT-proBNP in the days following the start of treatment and post surgery duration of hospital stay
15 Unknown  Combined Antihypertensive Therapy and Sexual Dysfunction
Conditions: Hypertension;   Sexual Dysfunction
Interventions: Drug: Felodipine add Irbesartan;   Drug: Felodipine add Metoprolol
Outcome Measures: Female Sexual Function Index (FSFI);   International Index of Erectile Function(IIEF);   Change of Systolic Blood Pressure in 2 Weeks;   Change of Systolic Blood Pressure in 4 Weeks;   Change of Systolic Blood Pressure in 8 Weeks;   Change of Systolic Blood Pressure in 12 Weeks;   Change of Systolic Blood Pressure in 24 Weeks;   Change of Systolic Blood Pressure in 48 Weeks;   Change of Diastolic Blood Pressure in 2 Weeks;   Change of Diastolic Blood Pressure in 4 Weeks;   Change of Diastolic Blood Pressure in 8 Weeks;   Change of Diastolic Blood Pressure in 12 Weeks;   Change of Diastolic Blood Pressure in 24 Weeks;   Change of Diastolic Blood Pressure in 48 Weeks;   Serum Estradiol in 24 Weeks;   Serum Estradiol in 48 Weeks;   Serum Testosterone in 24 Weeks;   Serum Testosterone in 48 Weeks;   Serum MDA in 24 Weeks;   Serum MDA in 48 Weeks;   Serum 8-OHdG in 24 Weeks;   Serum 8-OHdG in 48 Weeks;   Serum HNE in 24 Weeks;   Serum HNE in 48 Weeks
16 Unknown  Coreg CR, Blood Vessel Stiffness and Blood Vessel Function
Conditions: Endothelial Function;   Diabetes Mellitus;   Hypertension
Interventions: Drug: carvedilol;   Drug: Metoprolol extended release
Outcome Measure: Effect of Coreg CR compared to Toprol XL on endothelial function, vascular compliance, and parameters of oxidative stress from time of randomization to study drug termination
17 Recruiting A Phase Ⅲ Study of Extended-Release Carvedilol Sulfate for the Treatment of Heart Failure
Condition: Heart Failure
Interventions: Drug: Extended-Release Carvedilol Sulfate;   Drug: Sustained-release Metoprolol Succinate
Outcome Measures: Change From Baseline in left ventricular ejection fraction(LVEF) by ultrasound cardiogram;   Change From Baseline in Left Ventricular End Systolic Volume Index;   Change From Baseline in Left Ventricular End Diastolic Volume Index;   Incidence of Hospitalizations From Exacerbation of Heart Failure;   Incidence of Hospitalizations From All Causes;   Incidence of Deaths From All Causes;   Change From Baseline in New York Heart Association(NYHA)classification
18 Unknown  Beta-Blocker Before Extubation
Condition: Myocardial Ischemia
Intervention: Drug: Metoprolol
Outcome Measures: The rate of ischemia as judged by ST segment analysis in the 4h following extubation;   Rate-pressure product following extubation;   Troponin T elevations, the incidence of cardiogenic edema, and the rate of reintubation;   Pro-BNP levels
19 Recruiting Nebivolol Versus Sustained Release Metoprolol Succinate in Patients With Chronic Kidney Disease
Condition: Chronic Kidney Disease
Intervention:
Outcome Measures: Primary Efficacy;   Secondary Efficacy
20 Unknown  Nebivolol and the Endothelin (ET)-1 System
Conditions: Prehypertension;   Hypertension
Interventions: Drug: Nebivolol;   Drug: Metoprolol;   Drug: Placebo
Outcome Measure: ET-1-mediated vasoconstrictor tone