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MUSCULAR WEAKNESS and Furosemide

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MUSCULAR WEAKNESS Symptoms and Causes

Myasthenia gravis is a disease that causes weakness in your voluntary muscles. These are the muscles that you control. For example, you may have weakness in the muscles for eye movement, facial expressions, and swallowing. You can also have weakness in other muscles. This weakness gets worse with activity, and better with rest.

Myasthenia gravis is an autoimmune disease. Your body's immune system makes antibodies that block or change some of the nerve signals to your muscles. This makes your muscles weaker.

Other conditions can cause muscle weakness, so myasthenia gravis can be hard to diagnose. Tests used to make a diagnosis include blood, nerve, muscle, and imaging tests.

With treatment, the muscle weakness often gets much better. Medicines can help improve nerve-to-muscle messages and make muscles stronger. Other drugs keep your body from making so many abnormal antibodies. These medicines can have major side effects, so they should be used carefully. There are also treatments which filter abnormal antibodies from the blood or add healthy antibodies from donated blood. Sometimes, surgery to take out the thymus gland helps.

Some people with myasthenia gravis go into remission. This means that they do not have symptoms. The remission is usually temporary, but sometimes it can be permanent.

NIH: National Institute of Neurological Disorders and Stroke

Check out the latest treatments for MUSCULAR WEAKNESS

MUSCULAR WEAKNESS treatment research studies

Furosemide clinical trials, surveys and public health registries


Find Drug Side Effect reports



Furosemide Side Effects

Renal Failure Acute (363)
Hypokalaemia (211)
Dyspnoea (208)
Hypotension (178)
Dehydration (168)
Somnolence (152)
Dizziness (145)
Cardiac Failure (139)
Renal Failure (129)
Syncope (122)
Fall (116)
Asthenia (116)
Hyperkalaemia (109)
Fatigue (108)
Hyponatraemia (108)
Oedema Peripheral (103)
Blood Creatinine Increased (93)
Death (92)
Diarrhoea (88)
Confusional State (85)
Nausea (78)
Vomiting (76)
Renal Impairment (74)
Cardiac Arrest (64)
Cardiac Failure Congestive (63)
Condition Aggravated (63)
Pulmonary Oedema (63)
Malaise (63)
Pain (59)
Atrial Fibrillation (58)
Pneumonia (57)
Respiratory Failure (55)
Hypovolaemia (53)
Oedema (50)
Anaemia (49)
Metabolic Alkalosis (44)
Cough (44)
Electrocardiogram Qt Prolonged (42)
Blood Urea Increased (41)
Pyrexia (40)
Weight Decreased (39)
Toxicity To Various Agents (37)
Gait Disturbance (37)
Loss Of Consciousness (35)
Chest Pain (35)
Pemphigoid (35)
Polyuria (35)
Fluid Retention (34)
Rash (34)
Hypertension (34)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

After about 3 yrs of Lasix (20mg) I developed an unknown allergic reaction that caused blistering on my hands and feet. My feet would get 20-30 at a time and my hands would get hundreds at a time. I had to take medication to keep the breakouts minimi

I am taking 40mgs of furosemide daily it has really helped , i went for a drug screen for a job and it came back altered could you please tell me what caused this ?

I feel light headed, and my eyes feel dry as if wind is blowing. My vision has become unusually blurred and I there is a greenish yellowish tinge around my vision when I go outside in the light. When I first woke up this morning, everything I looked

I have the same feeling, definitely you are not strange.

My doctor has me on 80 mg of furosemide twice daily. What might I expect in side effects?

NOTHING RIGHT NOW BUT I DON>=.T N0 RIGHT NOW

So tired - so weak - hate how I feel

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

<strong></strong><span style='color: #ffa500;'>I am experiencing severe muscular <span style='color: #0000ff;'>pain/muscle tighteningin the diaphragm and sometimes &

<strong>I am on Cipralex now for about 2-3 months -10mg in the morning for depression, and now am experiencing chronic muscle weakness, chronic pain in both wrists and left hip, chronic fatigue, nausea, constant dizziness, tremors/shaky, restle

2 patients given thiocolchicoside reported of muscular stiffness,uneasiness,insomnia,breathlessness and feeling of restlessness, 2 out of 5 patients have reported such experiences after consuming thiocolchicoside.i strongly recommend to withdraw this

Afeccion cardiaca,pues a pesar de hacer ejercicio se me bloquearon las arterias,por mucho colesterol y tuvieron que hacerme un cateterismo, tengo once aos de que me detectaron la enfermedad. He perdido masa muscular pero nado ycamino dos o tres ve

After 18 months, great fatigue and muscular pain. Is this due to Intragam? consultant thinks I'm being fussy

After a 1 week course of Trimethoprim 200mg. I developed mild thrush on day3, muscle weakness for 1 day on the day after completion of the course and, 3 days after completion generalised urticaria. Not sure if this is delayed sensitivity but I assu

After finnishing the dose for Artequin I started feeling, body twitching, weakness,dizzness, body cramps, headache, neck pain, sore joints and now am at my sixth day after the dose and still experiencing the side effects..

After my first injection on Friday three weeks ago I experienced numbness and weakness Sunday night after injection along with a fever and night sweats. Went back to doctor on Tuesday and had an ultrasound to see if blockages or blood clots everythin

After takin tablets, i am feelimg somewhat uneasyness, feeling weakness, food intake is reduced

MUSCULAR WEAKNESS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Investigation of Gender Specificity of the Effects of Furosemide in Healthy Female and Male Volunteers
Condition: Healthy Male and Female Volunteers
Interventions: Drug: Furosemide;   Drug: aminohippurate sodium
Outcome Measures: pharmacokinetic parameter of Furosemide (AUC-24);   pharmacodynamic parameter of Furosemide (Sodium excretion in the urine);   pharmacogenetic parameters;   pharmacokinetic of aminohippuric acid;   other pharmacokinetic parameter of Furosemide;   other pharmacodynamic parameter of Furosemide
2 Not yet recruiting The Use of Furosemide in Patients on Dialysis
Condition: End Stage Renal Disease
Interventions: Drug: Withdrawal of Furosemide;   Drug: Furosemide administration
Outcome Measures: 24 hour urine sodium and water excretion;   Interdialytic weight gain
3 Recruiting Oral Metolazone and Intermittent Intravenous Furosemide Versus Continuous Infusion Furosemide in Acute Heart Failure
Condition: Acute Decompensated Heart Failure
Interventions: Drug: Intravenous Bolus Furosemide and Oral Metolazone;   Drug: Intravenous Continuous Infusion Furosemide
Outcome Measures: Daily net fluid output;   Patient Global Assessment Scale;   Daily urine output (mL urine out per mg Furosemide received);   Need for additional or alternative diuretic (crossover) or IV vasoactive therapy (study failure);   Death, rehospitalization, and unscheduled visit for HF to an emergency department or outpatient clinic;   Critically low potassium (< 3.5 mmol/L) and magnesium (< 1.6 mg/dL) concentrations;   Change in blood urea nitrogen or creatinine;   Number of hypotensive episodes defined as systolic blood pressure below 85 mmHg or greater than 10 mmHg below baseline (whichever is greater);   Total number of times antihypertensive doses are held due to low blood pressure
4 Unknown  Dopamine in Acute Decompensated Heart Failure (DAD-HF) Trial
Condition: Acute Heart Failure
Interventions: Drug: Furosemide;   Drug: low-dose dopamine + low-dose Furosemide
Outcome Measures: 1-year mortality or rehospitalization (all-cause, cardiovascular, non-cardiovascular, and due to worsening heart failure).;   60-day mortality or rehospitalization (all-cause, cardiovascular, non-cardiovascular, and due to worsening heart failure).
5 Unknown  The Influence of Furosemide on Fluid Balance and Intra-abdominal Pressure in Critically Ill Patients
Condition: Intra-Abdominal Hypertension
Intervention: Drug: Furosemide
Outcome Measures: intra-abdominal pressure;   serum creatinine;   need for renal replacement therapy;   ICU mortality;   acid-base status;   hospital and 28d mortality;   duration of mechanical ventilation;   ICU length of stay;   vasopressor dose;   fluid balance;   SOFA score
6 Not yet recruiting Inhaled Furosemide & Dyspnea
Condition: Dyspnea
Interventions: Other: CWS;   Drug: Furosemide;   Drug: Placebo
Outcome Measure: Sensory intensity (Borg 0-10 scale) ratings of dyspnea at isotime
7 Recruiting Peritoneal Dialysis vs Furosemide for Acute Kidney Injury After Cardiopulmonary Bypass
Condition: Acute Kidney Injury
Interventions: Drug: Furosemide;   Procedure: Peritoneal Dialysis
Outcome Measures: Fluid Balance;   Respiratory Support Administered;   NGAL Concentration;   Duration of cardiac ICU stay;   Duration of hospital stay;   All cause mortality;   Renal/electrolyte abnormalities;   Doses of Potassium Chloride or Arginine Chloride required;   B-Natriuretic Peptide
8 Recruiting Furosemide in Early Acute Kidney Injury
Condition: Acute Renal Failure
Interventions: Drug: Furosemide;   Drug: Normal Saline
Outcome Measures: Worsening AKI;   Fluid balance;   Renal replacement therapy (RRT);   Renal Recovery;   Survival
9 Unknown  Effect of Acetazolamide and Furosemide on Obesity-induced Glomerular Hyperfiltration
Condition: Obesity-induced Hyperfiltration
Intervention: Drug: Furosemide, acetazolamide
Outcome Measure: change in GFR and RPF
10 Recruiting Trial on Treatment With Inhaled Furosemide of Preterm and Term Neonates With Transient Tachypnoea
Condition: Transient Tachypnoea of the Newborn
Interventions: Drug: Furosemide;   Drug: Saline 0,9%
Outcome Measures: Reduction of the Silverman-Score;   Oxygen supplementation;   A need for secondary intubation and mechanical ventilation;   body weight;   CPAP-time;   blood electrolytes (Na+, K+, Ca++, HCO3-, Cl-);   blood gas (pH, pCO2,pO2)
11 Recruiting Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease
Condition: Fluid Overload
Interventions: Drug: Furosemide;   Drug: ethacrynic acid
Outcome Measures: Mean total urine output production in the first post-operative day;   Mean creatinine and NGAL values
12 Unknown  Using Furosemide to Prevent Fluid Overload During Red Blood Cell Transfusion in Neonates
Condition: Lung Disease
Interventions: Drug: Furosemide;   Drug: Saline
Outcome Measures: Cardiac chamber volume loading.;   Clinical cardio-respiratory stability (heart rate, blood pressure, respiratory rate, oxygen saturation, and oxygen requirement).;   Myocardial performance, cardiac input and output and pulmonary hemodynamics (echocardiograph exam).;   Changes in electrolyte balance, body weight and urine output.
13 Not yet recruiting Furosemide Treatment Before Blood Transfusion in Patients With Systolic Dysfunction
Condition: Anemia Treatment Among Patients Suffering From Left Ventricular Systolic Dysfunction
Interventions: Drug: Furosemide;   Drug: placebo normal saline
Outcome Measures: Diastolic echocardiographic changes following blood transfusion, with or without Furosemide treatment;   clinical outcome following blood transfusion, with or without Furosemide treatment
14 Unknown  Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis
Conditions: Respiratory Failure;   Volume Overload;   Hypernatremia
Interventions: Drug: Supplemental metolazone diuresis;   Drug: Placebo Comparator: Control-- Furosemide (lasix) only
Outcome Measures: Fluid balance;   Serum sodium;   Hyponatremia;   Time to extubation;   Acute Kidney Injury
15 Recruiting Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function
Conditions: Chronic Kidney Insufficiency;   Hemodialysis Treatment;   Diuresis Preserved
Intervention: Drug: Hydrochlorothiazide and Furosemide
Outcome Measures: To asses the effect of combined hydrochlorothiazide-Furosemide therapy on weight gain between haemodialysis sessions in patients with RRF;   To asses the effect of combined hydrochlorothiazide-Furosemide therapy on dialytic, clinical and analytical variables and use of the antihypertensive treatment
16 Not yet recruiting The Impact of TORasemide oN hemodynAmic and Neurohormonal Stress, and carDiac remOdeling in Heart Failure
Condition: Heart Failure
Interventions: Drug: Furosemide;   Drug: Torasemide
Outcome Measures: The influence of therapy on cardiovascular events associated with heart failure (deaths, hospitalisations);   The change of dosing of diuretic due to worsening of condition of patient.;   The change of NYHA (New York Heart Association) class - worsening or improvement
17 Unknown  Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure
Condition: Heart Failure
Interventions: Drug: Conivaptan;   Drug: Furosemide;   Drug: Conivaptan and Furosemide
Outcome Measures: renal hemodynamics renal blood flow and glomerular filtration rate;   measure plasma neurohormone levels
18 Unknown  The Effect of Continuous, Various Doses of Furosemide Drip on Hearing as Measured by Acoustic Emission
Condition: Hearing Status
Intervention:
Outcome Measure:
19 Recruiting Aerosol Inhalation Treatment for Dyspnea
Conditions: Healthy;   Dyspnea
Intervention: Drug: Furosemide
Outcome Measures: Subject rating of Breathing Discomfort (dyspnea);   Multidimensional Dyspnea Profile;   Urine output
20 Not yet recruiting A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011)
Conditions: Renal Impairment;   Heart Failure
Interventions: Drug: MK-7145 2 mg;   Drug: MK-7145 8 mg;   Drug: Furosemide;   Drug: Torsemide
Outcome Measures: Change from baseline in first 24hr UNa (Part I);   NT-proBNP values at 24 hours post last dose (Part II);   Fold change from baseline for serum creatinine (Part I);   Area under the concentration-time curve from time zero to 24 hours after dosing (AUC0-24hr) for MK-7145 (Part I);   Maximum plasma concentration (Cmax) for MK-7145 (Part I);   Trough plasma concentration (Ctrough) for MK-7145 (Part I);   Time to Cmax (Tmax) for MK-7145 (Part I);   Apparent terminal half-life (t1/2) for MK-7145 (Part I);   Serum creatinine measured at 24 hours post last dose (Part II);   Area under the concentration-time curve from time zero to 24 hours after dosing (AUC0-24hr) for MK-7145 (Part II);   Maximum plasma concentration (Cmax) for MK-7145 (Part II);   Trough plasma concentration (Ctrough) for MK-7145 (Part II);   Time to Cmax (Tmax) for MK-7145 (Part II);   Apparent terminal half-life (t1/2) for MK-7145 (Part II)