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MUSCULAR WEAKNESS and Ritalin

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MUSCULAR WEAKNESS Symptoms and Causes

Myasthenia gravis is a disease that causes weakness in your voluntary muscles. These are the muscles that you control. For example, you may have weakness in the muscles for eye movement, facial expressions, and swallowing. You can also have weakness in other muscles. This weakness gets worse with activity, and better with rest.

Myasthenia gravis is an autoimmune disease. Your body's immune system makes antibodies that block or change some of the nerve signals to your muscles. This makes your muscles weaker.

Other conditions can cause muscle weakness, so myasthenia gravis can be hard to diagnose. Tests used to make a diagnosis include blood, nerve, muscle, and imaging tests.

With treatment, the muscle weakness often gets much better. Medicines can help improve nerve-to-muscle messages and make muscles stronger. Other drugs keep your body from making so many abnormal antibodies. These medicines can have major side effects, so they should be used carefully. There are also treatments which filter abnormal antibodies from the blood or add healthy antibodies from donated blood. Sometimes, surgery to take out the thymus gland helps.

Some people with myasthenia gravis go into remission. This means that they do not have symptoms. The remission is usually temporary, but sometimes it can be permanent.

NIH: National Institute of Neurological Disorders and Stroke

Check out the latest treatments for MUSCULAR WEAKNESS

MUSCULAR WEAKNESS treatment research studies

Ritalin clinical trials, surveys and public health registries


Find Drug Side Effect reports



Ritalin Side Effects

Depression (131)
Aggression (111)
Agitation (101)
Headache (94)
Anxiety (88)
Abnormal Behaviour (80)
Disturbance In Attention (79)
Feeling Abnormal (77)
Nausea (76)
Insomnia (66)
Decreased Appetite (60)
Dizziness (56)
Suicidal Ideation (53)
Dyspnoea (51)
Hyperhidrosis (50)
Fatigue (48)
Tremor (47)
Hallucination (46)
Irritability (46)
Weight Decreased (46)
Somnolence (46)
Hypertension (45)
Confusional State (45)
Vomiting (44)
Tachycardia (44)
Malaise (43)
Suicide Attempt (41)
Nervousness (40)
Convulsion (39)
Hallucination, Auditory (39)
Attention Deficit/hyperactivity Disorder (38)
Bipolar Disorder (38)
Crying (37)
Heart Rate Increased (36)
Depressed Mood (36)
Memory Impairment (33)
Chest Pain (33)
Psychomotor Hyperactivity (33)
Pyrexia (33)
Fall (32)
Blood Pressure Increased (32)
Anorexia (32)
Loss Of Consciousness (31)
Psychotic Disorder (31)
Weight Increased (31)
Palpitations (30)
Abdominal Pain Upper (30)
Asthenia (29)
Blood Creatine Phosphokinase Increased (25)
Apathy (25)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

<strong></strong><span style='color: #ffa500;'>I am experiencing severe muscular <span style='color: #0000ff;'>pain/muscle tighteningin the diaphragm and sometimes &

<strong>I am on Cipralex now for about 2-3 months -10mg in the morning for depression, and now am experiencing chronic muscle weakness, chronic pain in both wrists and left hip, chronic fatigue, nausea, constant dizziness, tremors/shaky, restle

2 patients given thiocolchicoside reported of muscular stiffness,uneasiness,insomnia,breathlessness and feeling of restlessness, 2 out of 5 patients have reported such experiences after consuming thiocolchicoside.i strongly recommend to withdraw this

Afeccion cardiaca,pues a pesar de hacer ejercicio se me bloquearon las arterias,por mucho colesterol y tuvieron que hacerme un cateterismo, tengo once aos de que me detectaron la enfermedad. He perdido masa muscular pero nado ycamino dos o tres ve

After 18 months, great fatigue and muscular pain. Is this due to Intragam? consultant thinks I'm being fussy

After a 1 week course of Trimethoprim 200mg. I developed mild thrush on day3, muscle weakness for 1 day on the day after completion of the course and, 3 days after completion generalised urticaria. Not sure if this is delayed sensitivity but I assu

After finnishing the dose for Artequin I started feeling, body twitching, weakness,dizzness, body cramps, headache, neck pain, sore joints and now am at my sixth day after the dose and still experiencing the side effects..

After my first injection on Friday three weeks ago I experienced numbness and weakness Sunday night after injection along with a fever and night sweats. Went back to doctor on Tuesday and had an ultrasound to see if blockages or blood clots everythin

After takin tablets, i am feelimg somewhat uneasyness, feeling weakness, food intake is reduced

MUSCULAR WEAKNESS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV
Condition: HIV Dementia
Interventions: Drug: Long acting methylphenidate;   Drug: Matched placebo
Outcome Measures: Change in rate of reaction time as measured by neuropsychological testing;   Number of Subjects with Adverse Events as Measures of Safety and Tolerability of Concerta in HIV infected adults
2 Recruiting Effects of Methylphenidate (Ritalin®) on the Neural Basis of Anxiety
Condition: PTSD
Interventions: Drug: Methylphenidate;   Drug: Placebo
Outcome Measures: Changes in blood oxygenation level-dependent BOLD signal responses;   Changes in BOLD signal responses;   Changes in skin conductance response;   Latency and accuracy during a interoceptive stimulus task
3 Not yet recruiting The Effect of Ritalin (Methylphenidate Hydrochloride) on Pain and Auditory Sensitivity: an Exploratory Double-blind Randomized Controlled Trial on Healthy Subjects
Condition: Pharmacological Action (PA)
Interventions: Drug: methylphenidate hydrochloride;   Drug: Sugar pill (placebo)
Outcome Measures: Experimental pain intensity measured on a visual analogue scale (0-100);   effect of Ritalin on auditory sensitivity, measured by the response to different auditory stimulations;   pain intensity (NPS 0-100) in response to thermal stimuli and the measures of the auditory tests.
4 Not yet recruiting Identifying Characteristic Signature of Attention Deficit / Hyperactivity Disorder (ADHD) and Ritalin Treatment
Condition: "Attention Deficit Hyperactivity Disorder"
Interventions: Drug: Ritalin;   Drug: Placebo
Outcome Measure: Resting oscillation activity and Event-related-Potentials in Attention Deficit / Hyperactivity Disorder (ADHD) and healthy subjects.
5 Not yet recruiting Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI
Condition: Traumatic Brain Injury
Interventions: Drug: methylphenidate;   Drug: Placebo
Outcome Measures: Relationship between tonic dopamine release (measured by displacement of [11C]-raclopride by oral methylphenidate) and change in processing speed between baseline and after methylphenidate treatment.;   Relationship between D2/D3 receptor availability in ventral striatum and prefrontal cortex and neuropsychologic deficits.;   Relationship between tonic dopamine release in the ventral striatum and prefrontal cortex with neuropsychologic deficits after TBI.;   Relationship between D2/D3 receptor availability and functional connectivity of the prefrontal cortex with nodes of the default mode network.;   Relationship between TMS-induced short-interval cortical inhibition of M1 and tonic dopamine release.;   Test motivation and reward on and off methylphenidate in TBI patients.
6 Unknown  Amantadine Versus Ritalin in the Treatment of Attention Deficit Hyperactivity Disorder (ADHD)
Condition: Attention Deficit Hyperactivity Disorder
Interventions: Drug: Amantadine;   Drug: Ritalin
Outcome Measure: The mean decrease in ADHD -RS-IV score from baseline will be used as the main outcome measure of response of ADHD treatment.
7 Recruiting Methylphenidate to Improve Balance and Walking in MS
Condition: Multiple Sclerosis
Interventions: Drug: Methylphenidate (Ritalin);   Drug: Placebo
Outcome Measures: Timed Up and Go time (TUG time);   Automatic Postural Response (APR) Latency (in sec);   Timed 25 Foot Walk (T25FW in secs);   Pittsburgh Sleep Quality Assessment Questionnaire score;   Modified Fatigue Index Scale score;   Vestibular-Ocular Reflex time (in secs)
8 Unknown  Study of Methylphenidate as Add on Therapy in Depressed Cancer Patients
Condition: Depression
Interventions: Drug: Methylphenidate;   Drug: Placebo
Outcome Measures: depressive symptoms;   Distress level
9 Recruiting Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study
Conditions: Healthy;   Substance-related Disorder;   Mood Disorder
Interventions: Drug: Methylphenidate;   Drug: Modafinil;   Drug: MDMA;   Drug: Placebo
Outcome Measures: Effect on amygdala and striatum BOLD signal responses to emotional stimuli;   Effects on cognitive performance and associated BOLD signal changes in frontal areas;   Subjective effects;   Neuroendocrine effects;   Empathy and social behavior;   Physiological effects of methylphenidate, modafinil, and MDMA;   Genetic Polymorphisms;   Pharmacokinetics of methylphenidate, modafinil, and MDMA
10 Recruiting Methylphenidate vs. Risperidone for the Treatment of Children and Adolescents With ADHD and Disruptive Disorders
Conditions: Attention Deficit/Hyperactivity Disorder;   Oppositional Defiant Disorder;   Conduct Disorder
Interventions: Drug: Methylphenidate;   Drug: Risperidone
Outcome Measures: Change from baseline of aggressive behaviors.;   Clinical Global Impression - Improvement scale (CGI-I) questionnaire;   ADHD-RS questionnaire;   Children's Depression Rating Scale (CDRS) questionnaire;   Young Mania Rating Scale (YMRS) questionnaire;   Children Sleep Habits Questionnaire (CSHQ);   Clinical Global Impression - Severity (CGI-S) questionnaire
11 Recruiting The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)
Conditions: Attention Deficit/Hyperactivity Disorder Combined Type;   ADHD Predominantly Inattentive Type;   ADHD Predominantly Hyperactivity Type;   ADHD-not Other Specified
Intervention: Drug: Methylphenidate- Ritalin IR (Immediate Release)
Outcome Measures: Clinical Global Impression-Improvement scale;   overall ADHD-Rating Scale (ADHD-RS) score
12 Recruiting Methylphenidate as Treatment Option of Fatigue in Multiple Sclerosis
Conditions: Multiple Sclerosis;   Fatigue
Interventions: Drug: Methylphenidate modified release;   Drug: Maltodextrin
Outcome Measures: Change of Fatigue as measured by Fatigue Severity Scale;   Change of Fatigue as measured by Modified Fatigue Impact Scale (MFIS)
13 Not yet recruiting Methylphenidate on Intracortical Inhibition in Methamphetamine Abusers Attention Deficit Hyperactivity Disorder (ADHD)
Condition: Attention Deficit Hyperactivity Disorder
Intervention: Other: methylphenidate tablets and Inter-stimulus Intervals (ISI)
Outcome Measures: Conners ADHD Rating Scale;   Change of Motor Evoked Potential (MEP)
14 Recruiting Control of Cognition
Conditions: Healthy;   Attention Deficit Hyperactivity Disorder;   Alcohol Dependence;   Attention Deficit Hyperactivity Disorder and Alcohol Dependence
Interventions: Drug: Methylphendiate;   Drug: Naltrexone;   Drug: Placebo
Outcome Measures: Identify abnormalities in prefrontal control neural circuits underlying attention control, motor control, and appetitive control;   Characterize effects of methylphenidate and naltrexone on neural circuits in prefrontal cortex associated with attention control, motor control, and appetitive control;   Reaction time on the Multi-Source Interference Task;   Accuracy on the Multi-Source Interference Task;   Reaction time variability on the Multi-Source Interference Task
15 Recruiting Multimodal Therapy for Treatment of Fatigue
Condition: Prostate Cancer
Interventions: Other: Placebo;   Drug: Methylphenidate;   Behavioral: Counseling Sessions;   Other: Sham Exercise;   Other: Standardized Exercise Intervention Program;   Other: Cognitive Behavioral Therapy (CBT)
Outcome Measure: Change in Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F) subscale scores
16 Recruiting Methylphenidate for Attention Problems After Pediatric TBI
Conditions: Traumatic Brain Injury;   TBI;   ADHD
Interventions: Drug: Methylphenidate;   Drug: Placebo
Outcome Measures: Parent report measures;   Neuropsychological Testing;   Teacher Report Measures
17 Not yet recruiting Reversal of General Anesthesia With Methylphenidate
Conditions: Post Operative Cognitive Dysfunction;   Emergence From Anesthesia
Intervention: Drug: Methylphenidate
Outcome Measures: Number of Participants with Adverse Events as a Measure of Safety and Tolerability;   Time to emergence from general anesthesia
18 Recruiting Impact of CES1 Genotype on Metabolism of Methylphenidate
Conditions: Carboxylesterase 1 (CES1) Genotype;   CES1 Activity
Intervention: Drug: Methylphenidate
Outcome Measures: Plasma concentration of methylphenidate and Ritalinic acid;   Metabolomic Profile
19 Recruiting A Comparison of Methylphenidate and Cognitive Behavioural Therapy for the Treatment of Binge Eating Disorder
Condition: Binge-Eating Disorder
Interventions: Drug: Methylphenidate;   Behavioral: Cognitive Behavioral Therapy
Outcome Measures: Frequency of binge episodes/days, as assessed by prospective daily binge diary;   Frequency of objective binge episodes and overall illness severity, as assessed by both the Eating Disorder Examination Interview and Questionnaire;   Clinician impression of illness severity and improvement, as assessed by the Clinical Global Impression scale;   Quality of life, as assessed by the Quality of Life Inventory;   Associated features of binge eating as captured by the Dutch Eating Behavior Questionnaire and Binge Eating Scale;   Body Mass Index
20 Not yet recruiting Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD
Conditions: Attention-deficit/Hyperactivity Disorder;   Autism Spectrum Disorder
Intervention: Drug: Methylphenidate extended-release liquid formulation
Outcome Measure: Adult ADHD Investigator Symptom Report Scale (AISRS)