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NEURALGIA and Lyrica

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NEURALGIA Symptoms and Causes

What is shingles?

Shingles is an outbreak of rash or blisters on the skin. It is caused by the varicella-zoster virus - the same virus that causes chickenpox. After you have chickenpox, the virus stays in your body. It may not cause problems for many years. But as you get older, the virus may reappear as shingles.

Is shingles contagious?

Shingles is not contagious. But you can catch chickenpox from someone with shingles. If you've never had chickenpox or the chickenpox vaccine, try to stay away from anyone who has shingles.

If you have shingles, try to stay away from anyone who has not had chickenpox or the chickenpox vaccine, or anyone who might have a weak immune system.

Who is at risk for shingles?

Anyone who has had chickenpox is at risk for getting shingles. But this risk goes up as you get older; shingles is most common in people over age 50.

People with weakened immune systems are at higher risk of getting shingles. This includes those who

  • Have immune system diseases such as HIV/AIDS
  • Have certain cancers
  • Take immunosuppressive drugs after an organ transplant

Your immune system may be weaker when you have an infection or are stressed. This can raise your risk of shingles.

It is rare, but possible, to get shingles more than once.

What are the symptoms of shingles?

Early signs of shingles include burning or shooting pain and tingling or itching. It is usually on one side of the body or face. The pain can be mild to severe.

One to 14 days later, you will get a rash. It consists of blisters that typically scab over in 7 to 10 days. The rash is usually a single stripe around either the left or the right side of the body. In other cases, the rash occurs on one side of the face. In rare cases (usually among people with weakened immune systems), the rash may be more widespread and look similar to a chickenpox rash.

Some people may also have other symptoms:

  • Fever
  • Headache
  • Chills
  • Upset stomach
What are the complications of shingles?

Shingles can cause complications:

  • Postherpetic Neuralgia (PHN) is most common complication of shingles. It causes severe pain in the areas where you had the shingles rash. It usually gets better in a few weeks or months. But some people can have pain from PHN for many years, and it can interfere with daily life.
  • Vision loss can happen if shingles affects your eye. It may be temporary or permanent.
  • Hearing or balance problems are possible if you have shingles within or near your ear. You may also have weakness of the muscles on that side of your face. These problems can be temporary or permanent.

Very rarely, shingles can also lead to pneumonia, brain inflammation (encephalitis), or death.

How is shingles diagnosed?

Usually your health care provider can diagnose shingles by taking your medical history and looking at your rash. In some cases, your provider may scrap off tissue from the rash or swab some fluid from the blisters and send the sample to a lab for testing.

What are the treatments for shingles?

There is no cure for shingles. Antiviral medicines may help to make the attack shorter and less severe. They may also help prevent PHN. The medicines are most effective if you can take them within 3 days after the rash appears. So if you think you might have shingles, contact your health care provider as soon as possible.

Pain relievers may also help with the pain. A cool washcloth, calamine lotion, and oatmeal baths may help relieve some of the itching.

Can shingles be prevented?

There are vaccines to prevent shingles or lessen its effects. The Centers for Disease Control and Prevention recommends that healthy adults 50 years and older get the Shingrix vaccine. You need two doses of the vaccine, given 2 to 6 months apart. Another vaccine, Zostavax, may be used in certain cases.

Check out the latest treatments for NEURALGIA

NEURALGIA treatment research studies

Lyrica clinical trials, surveys and public health registries


Find Drug Side Effect reports



Lyrica Side Effects

Dizziness (2971)
Pain (2819)
Weight Increased (2413)
Somnolence (2054)
Oedema Peripheral (1606)
Vision Blurred (1487)
Feeling Abnormal (1476)
Fall (1266)
Fatigue (1245)
Insomnia (1182)
Malaise (1160)
Gait Disturbance (1146)
Nausea (1143)
Headache (1132)
Pain In Extremity (1082)
Confusional State (942)
Dyspnoea (930)
Depression (783)
Off Label Use (740)
Tremor (737)
Hypoaesthesia (679)
Asthenia (676)
Balance Disorder (669)
Dry Mouth (664)
Anxiety (619)
Diarrhoea (597)
Disturbance In Attention (577)
Arthralgia (559)
Memory Impairment (550)
Convulsion (542)
Paraesthesia (530)
Muscle Spasms (487)
Rash (486)
Withdrawal Syndrome (462)
Loss Of Consciousness (458)
Activities Of Daily Living Impaired (456)
Muscular Weakness (453)
Joint Swelling (452)
Amnesia (447)
Pruritus (430)
Back Pain (421)
Vomiting (413)
Hypertension (412)
Myalgia (407)
Speech Disorder (405)
Constipation (402)
Suicidal Ideation (397)
Weight Decreased (396)
Burning Sensation (392)
Hyperhidrosis (382)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
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Celebrex (12876 )
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Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
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Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
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Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
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Wellbutrin (6324)
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Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

<span style='font-family: Arial;'>I was subscribed Lyrica for my fibromyalgia and took it for about 3 weeks and as a result I ended up jumping through a window (resulting in permanent injuries) and wound up in a mental inst

Extreme fatigue, sleeplessness, short term memory and speech difficulties, Edema, weight gain, stumbling, shortness of breath, numbness in both legs, and completely kills ability to achieve orgasm.

After a little over 2 weeks on Lyrica I awoke one morning with blurred vision. It has been almost 2 weeks and even after stopping the Lyrica I still can not focus my eyes. I am told that my eyes are focusing in and out and if I try hard enough I get

After one dose of 50mg felteuphoric, dizzy,out of touch with reality and extremely depressed; unable to functionas normal.great for pain but don't think I can continue withthis.

Can anyone explain how i can feel euphoric but suicidal at the same time on Lyrica?

Cant sleep,hair loss.depressed

Doctors are told what to prescribe and its ridiculous because they don't test enough on the medication. Pharmaceutical companies want to get a patent asap so its an automatic billion in the bank because of the 18 year patent law.

Does Lyrica really cause weight gain in all patients who take it

Drowsiness, double vision, weight gain

Earlier this month I started Lyrica. Was on only 50mh pr night for 4 nights before I had an allergic reation. Had to stop taking it, took over a week for the allergic symptoms to stop! Just reported to the FDA.

<b>Describe Your Bisoprolol Experience Here:&lt;/b Trigeminal neuralgia. , left neurological chest pain Dose 1.25 twice daily</b>

Gleevec aggravating trigeminal neuralgia

Hi I take Oxcarbazepine for trigeminal neuralgia and i am having difficulty concentrating and seeing clearly, does anyone else have the same or similar experience

Hi Joe - if you already have heart failure, DO NOT take Lyrica. Warnings are on the leaflet within the tablet package. My husband increased his dosage (ignoring my warnings) to 750mg/day for severe trigeminal neuralgia, way above the recommended maxi

I am a homeopath.I am treating a patient, who is suffering from trigeminal neuralgia since 2 yrs.Previously he was a victim of repeated attacks of colds &amp; cough, &amp; he was using Actifed oral, half tablet twice/week,for 20 yrs.RCC stopp

I have an AVM. I was born with this, and it was first found in an MRI 13 years ago. While testing for my symptoms of facial pain (Neuralgia They didnt know it at the time) 2-1/2 years ago, I had another MRI. These results were compared to t

I was prescribed Lyrica by my doctor right after my 18th birthday. I was diagnosed with Post Herpetic Neuralgia (after pain from Shingles) when I was seventeen. Lyrica was the most horrible thing I've ever taken. While taking Lyrica, I was taking 18

James, I realised yours is an old posting, but 3 x 300mg a day is WAY over the maximum recommended dosage! My husband has trigeminal neuralgia and was so desperate to relieve the pain he put himself on 750mg a day (maximum is 600mg). As a direct resu

My husband died in Dec 2007 due to a contradiction of taking Lyrica with Effexor XR. He was taking Lyrica for post herpetic neuralgia. His doc decided in Noc '07 to have him take it daily (ie prophlactically), 2 weeks before his death the doc ha

Trigeminal neuralgia and Chantix. hs anyone been diagonoised with since stopping Chantix.

NEURALGIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting A Placebo-Controlled Trial of Pregabalin (Lyrica) for Irritable Bowel Syndrome
Condition: Irritable Bowel Syndrome
Interventions: Drug: Pregabalin (Lyrica);   Drug: Placebo
Outcome Measures: Primary aim: Collect preliminary data comparing effects of Pregabalin and placebo on abdominal pain/discomfort on bowel symptom score (BSS), overall BSS score, and adequate relief of irritable bowel syndrome (IBS) symptoms in patients with IBS;   To compare the effect of Pregabalin and placebo on self-reported overall and individual BSS scores;   compare effect of Pregabalin and placebo on adequate relief of IBS pain or discomfort at least 50% of the time;   To compare effect of Pregabalin and placebo on overall and individual BSS scores;   To compare the effect of Pregabalin and placebo on the proportion of patients with at least 3 point changes in 11 point pain and IBS scores
2 Recruiting A Study of Pregabalin (Lyrica) Augmentation in Serotonin Reuptake Inhibitor-Refractory Obsessive Compulsive Disorder
Condition: Obsessive-Compulsive Disorder
Interventions: Drug: pregabalin;   Drug: Placebo
Outcome Measures: Yale-Brown-Obsessive-Compulsive-Scale;   Clinical Global Impression - Improvement;   Montgomery Asberg Depression Rating Scale;   Sheehan Disability Scale;   Beck Depression Inventory;   Clinical Global Impression - Severity;   Saving Inventory - Revised;   Dimensional Yale-Brown-Obsessive Compulsive Scale (D-Y-BOCS);   Padua Inventory
3 Not yet recruiting Efficacy and Safety of KW21052 Compared to Lyrica in the Diabetic Patients With Neuropathic Pain
Condition: Diabetic Neuropathy
Interventions: Drug: KW21052;   Drug: Lyrica;   Drug: Lyrica (low dose);   Drug: Placebo of KW21052;   Drug: Placebo of Lyrica
Outcome Measures: Numerical pain rating scale (NRS);   Change on on the numerical pain rating scale (NRS);   Response rate;   Clinical Global Impression of Change (CGIC);   Improved quality of life (QoL);   Drug compliance;   Adverse events
4 Recruiting The Effects of Pregabalin on Postoperative Pain After Cardiac Surgery
Condition: Postoperative Pain
Interventions: Drug: Pregabalin 75mg;   Drug: pregabalin 150 mg;   Drug: Placebo
Outcome Measures: opioid consumption and other analgesics after surgery;   Remaining surgery related pain and analgesics consumption
5 Unknown  Imipramine and Pregabalin Combination in Painful Polyneuropathy
Condition: Polyneuropathy
Interventions: Drug: Imipramine;   Drug: Pregabalin;   Drug: Imipramine, pregabalin;   Drug: Placebo
Outcome Measures: Total pain intensity as measured by numeric rating scale 0-10 points.;   Verbal pain relief scale with 6 classes;   Specific pain symptom rated by numeric rating scales 0-10 points;   Rating of evoked pains symptoms (pressure, brush, repetitive pin-prick, cold) as measured by numeric rating scales 0-10 points;   Sleep disturbance as measured by numeric rating scale 0-10 points;   Consumption of escape medication (number of tablets of paracetamol);   Health related quality of life (SF-36);   Major Depression Inventory (MDI)
6 Recruiting A Study Evaluating the Efficacy and Safety of Pregabalin Against Frequent Muscle Cramp in Patients With Liver Cirrhosis
Conditions: Muscle Cramp;   Liver Cirrhosis
Interventions: Drug: Pregabalin;   Drug: Placebo
Outcome Measures: mean reduction rates of the frequency of muscle cramps between pregabalin and placebo groups;   Response rates , Mean change in the average cramp pain intensity , peripheral nerve excitability , the quality of life, quality of sleep , safety
7 Recruiting A Safety, Efficacy and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric and Adult Subjects With Primary Generalized Tonic-Clonic (i.e., Grand Mal) Seizures.
Condition: Generalized Tonic Clonic Seizures
Interventions: Drug: Pregabalin Dose Level 1;   Drug: Pregabalin Dose Level 2;   Drug: Placebo
Outcome Measures: Percent reduction of 28 day seizure rate for all PGTC seizures relative to placebo during the double blind assessment phase.;   Responder rate, defined as the proportion of subjects who had at least a 50% reduction in 28 day PGTC seizure.
8 Unknown  Efficacy of Pregabalin in the Management of Chronic Uremic Pruritus
Condition: Uremic Pruritus
Interventions: Drug: Pregabalin;   Drug: Placebo
Outcome Measures: Reduction of UP by more than 50% after Pregabalin administration;   Reduction of chronic pain of various origin and improvement in insomnia after Pregabalin administration
9 Recruiting Study To Evaluate Efficacy, Safety And Tolerability Of Lyrica In Patients With Painful Diabetic Peripheral Neuropathy
Condition: Diabetic Neuropathy, Painful
Interventions: Drug: Pregabalin;   Drug: Placebo matched with pregabalin
Outcome Measures: Endpoint mean pain score based on the pain scores from the subject's daily pain rating scale;   Weekly mean pain scores from the subject's daily pain rating scale;   Weekly mean sleep interference scores from the subject's daily sleep interference scale;   Responder rates with at least a 30% reduction from baseline in weekly mean pain score;   Change from baseline in Short-Form McGill Pain Questionnaire at week 9;   Change from baseline in Pain Visual Analogue Scale at week 9;   Change from baseline in Medical Outcomes Study -Sleep Scale at week 9;   The Subject Global Impression of Change at week 9;   The Clinical Global Impression of Change at week 9;   Change from baseline in Hospital Anxiety and Depression Scale at week 9
10 Recruiting Effects of Pregabalin on Post-cesarean Pain
Condition: Uncomplicated Singleton Pregnancies
Interventions: Drug: Placebo;   Drug: Pregabalin 300 mg group;   Drug: Pregabalin 150 mg group
Outcome Measures: cumulative patient controlled morphine consumptions;   postoperative pain scores;   neonatal Apgar scores;   Neurologic and adaptive capacity scores;   Maternal sedation;   Maternal nausea and vomiting
11 Recruiting Safety, Tolerability and Preliminary Efficacy of AZD5213 in Combination With Pregabalin in Subjects With PDN and Good Pain Reporting Ability
Condition: Diabetic Neuropathy, Painful; Diabetic Neuropathies
Interventions: Drug: AZD5213 + pregabalin;   Drug: Placebo;   Drug: pregabalin capsules
Outcome Measures: Change in Item 5 of Brief Pain Inventory Diabetic Peripheral Neuropathy version (BPI-DPN);   Incidence and severity of Treatment Emergent Adverse Events;   Vital signs ( blood pressure, heart rate, weight and temperature);   Clinical Laboratory Evaluations;   Medical Outcomes Study (Revised) Sleep Scale (MOS-R);   Columbia Suicide Severity Rating Scale (CSSR-S);   Neuropathic Pain Symptom Inventory (NPSI);   Sleep Interference Scale (SIS)
12 Unknown  Perioperative Administration of Pregabalin for Pain After Septoplasty
Condition: Deviated Nasal Septum
Interventions: Drug: Pregabalin (Lyrica);   Drug: Vitamin complex (placebo)
Outcome Measures: Pain score (Verbal numerical rating scale, VNRS and Visual Analogue Scale, VAS);   The number of patients with side effects including Nausea and vomiting, sedation, headache, dizziness;   The number of patients who required additional analgesics during admission
13 Not yet recruiting Pregabalin for the Treatment and Prevention of Spinal Cord Injury Neuropathic Pain
Conditions: Neuropathic Pain;   Spinal Cord Injuries
Interventions: Drug: Pregabalin;   Drug: Placebo
Outcome Measures: Daily at-level non-evoked pain intensity measured with the numerical rating scale (0-10) expressed as the mean 7-day pain intensity;   Weekly below-level non-evoked pain intensity measured with the numerical rating scale (0-10);   Weekly evaluation of at-level neuropathic pain symptoms using the "Neuropathic Pain Symptoms Inventory" (NPSI);   Weekly evaluation of at-level neuropathic pain intensity and interference using the "Brief Pain Inventory" (BPI);   Weekly evaluation of the change in at-level non-evoked neuropathic pain using the "Patient Global Impression Change" (PGIC);   Weekly evaluation of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS);   Weekly evaluation of spasm frequency below the spinal cord injury using the Penn questionnaire;   Measurement of the amplitude of cold and heat sensory evoked potentials (Cz-Fz) studied above (C4) and at-level of the SCI;   Serum TNF-R1 level;   Weekly at-level non-evoked pain intensity measured with the numerical rating scale (0-10) 28 days after the termination of the clinical trial;   Number of Paracetamol tablets used as rescue medication during the week;   Prevalence and type of adverse events in patients treated with pregabalin;   Unblinding testing: patient and investigator will be asked for the treatment they think to have received. Reasons for their judgement (efficacy and safety) will also be asked.
14 Recruiting Adolescent Fibromyalgia Study
Condition: Fibromyalgia
Interventions: Drug: placebo;   Drug: pregabalin (Lyrica)
Outcome Measures: Endpoint mean pain score from daily pain diary;   Endpoint mean sleep quality score from the daily sleep diary;   Pain Numeric Rating Scale (Pain-NRS) at Termination Visit;   Patient Global Impression of Change at Termination;   Parent Global Impression of Change at Termination Visit;   Fibromyalgia Impact Questionnaire for Children at Termination Visit;   Frequency and severity of adverse events at every visit.;   Physical and neurological exams.;   Vital signs.;   Suicidality Tracking Scale (STS).;   12-Lead Electrocardiogram (ECG).;   Laboratory tests: hematology, chemistry, serum pregnancy, urinalysis.;   Reproductive hormone monitoring (females only);   Tanner staging-assessment of pubertal status (females only);   Pharmacokinetic endpoint: A population pharmacokinetic analysis will be performed using the sparse PK samples obtained at V6.
15 Recruiting Effect of Pregabalin in Patients With Radiation-Induced Peripheral Neuropathic Pain
Condition: Neuropathic Pain
Interventions: Drug: Pregabalin;   Drug: Placebo
Outcome Measures: Daily Pain Rating Scale (DPRS) at week 12;   The modified Brief Pain Inventory-short form (mBPI);   Daily Sleep Interference Scale(DSIS)
16 Unknown  Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain
Conditions: Inguinal Hernia;   Postoperative Pain
Intervention: Drug: Pregabalin
Outcome Measures: Study is constructed to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy for post operative pain at Alert, 15, 30, 45, 60 and 120 min, Day 1, Day 2 and Day 3.;   Opiod Sparing;   Side effect of medication
17 Not yet recruiting Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia
Conditions: Taxane;   Drug-related Side Effects and Adverse Reactions;   Pain;   Breast Cancer
Interventions: Drug: Pregabalin;   Drug: Placebo
Outcome Measures: Integrated Numeric Pain Scores and Rescue Analgesic Medication Requirement as calculated by the method proposed by Silverman et al (Silverman, O'Connor et al. 1993).;   Numeric Pain Score (NPS);   The additional number of hours spent in horizontal position (∆HHP**);   FACT-taxane score
18 Recruiting Evaluation of Preoperative Use of Pregabalin on Postoperative Analgesia After Laparoscopic Colorectal Surgery
Condition: Postoperative Pain
Interventions: Drug: Pregabalin;   Drug: Placebo;   Drug: Morphine
Outcome Measures: Postoperative opioid consumption;   Postoperative pain;   Side- effects;   Chronic Pain;   Hospital stay
19 Unknown  Randomized Study of Pregabalin for Pain Reduction in Patients With Rest Pain and Lower Limb Ischemia
Conditions: Critical Limb Ischemia;   Arterial Occlusive Disease;   Pain;   Ischemia
Interventions: Drug: pregabalin;   Drug: placebo
Outcome Measures: Reduction in Rating Scale (RS) pain compared to baseline. RS Pain will be assessed at 7, 14 days for all participants and after 28 and 56 days for patients continuing the extended phase of study.;   Improvement in the Short Form 36 (SF-36) parameter "bodily pain".;   The amount, dose and duration of concomitant pain medication use during study compared to use before study.;   Safety outcomes and adverse events will be examined and recorded throughout the study. Patient reported dizziness will be recorded separately in the CRF, as well as blood pressure at visits.
20 Unknown  Pain Relief Following Arthroscopic Rotator Cuff Repair: Perioperative Pregabalin Administration Versus Interscalene Brachial Plexus Block
Condition: Pain
Interventions: Drug: Pregabalin;   Procedure: ISBPB - interscalene brachial plexus block
Outcome Measure: To compare postoperative pain relief by pregabalin versus ISBPB following arthroscopic rotator cuff repair