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OBESITY and Phentermine

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OBESITY Symptoms and Causes

Obesity means having too much body fat. It is different from being overweight, which means weighing too much. The weight may come from muscle, bone, fat, and/or body water. Both terms mean that a person's weight is greater than what's considered healthy for his or her height.

Obesity occurs over time when you eat more calories than you use. The balance between calories-in and calories-out differs for each person. Factors that might affect your weight include your genetic makeup, overeating, eating high-fat foods, and not being physically active.

Being obese increases your risk of diabetes, heart disease, stroke, arthritis, and some cancers. If you are obese, losing even 5 to 10 percent of your weight can delay or prevent some of these diseases. For example, that means losing 10 to 20 pounds if you weigh 200 pounds.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Check out the latest treatments for OBESITY

OBESITY treatment research studies

Phentermine clinical trials, surveys and public health registries


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Injury (13)
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Hypercoagulation (5)
Alanine Aminotransferase Increased (5)
Mental Disorder (5)
Heart Rate Increased (5)
Pneumomediastinum (5)
Ventricular Tachycardia (5)
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Pyrexia (5)
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OBESITY Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Change in Cognitive Function in Obese Patients After Bariatric Surgery - an Observational Study
Conditions: Obesity;   Bariatric Surgery
Intervention: Other: Observation
Outcome Measures: performance in a neuropsychological test battery before and after surgery;   performance in neuropsychological test battery 12 month after surgery compared to performance after 6 month and baseline performance;   performance in further cognitive tests;   surrogat parameters, blood parameters
2 Recruiting Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea
Conditions: Obesity;   Diabetes;   Obstructive Sleep Apnea
Interventions: Other: Ketogenic diet;   Drug: Orlistat;   Other: Standardized diet
Outcome Measures: Change of body mass index from baseline in 9 months period;   Change from baseline in glucose blood level in patients with diabetes mellitus in 9 months.;   Change of apnea/hypopnea index in patients with obstructive sleep apnea in patients with Obesity;   To evaluate safety of ketogenic diet as a treatment of Obesity.
3 Recruiting Course of Obesity and Extreme Obesity in Adolescents
Conditions: Obesity;   Extreme Obesity
Intervention:
Outcome Measures: adherence with structured care;   percentage of subjects that can be integrated into the job-market or into an apprenticeship training position;   percentage of subjects that undergo the recommended diagnostic procedures;   changes in somatic co-morbidities;   changes in psychiatric co-morbidities;   compliance with treatment of somatic co-morbidities;   compliance with treatment of psychiatric co-morbidities;   changes in health related quality of life;   changes in socio-economic status;   incidence of extreme Obesity;   changes in BMI-SDS;   predictors of the above outcomes
4 Recruiting Obesity and Brain: Genes and Environment
Condition: Obesity
Intervention:
Outcome Measures: The difference in neuronal activity in CNS reward and satiety circuits as represented by BOLD functional magnetic resonance imaging (fMRI) signal change from baseline (%) in response to food-related stimuli within Obesity discordant MZ twin pairs.;   The difference in neuronal activity in CNS reward and satiety circuits as represented by BOLD fMRI signal change from baseline (%) in response to food-related stimuli between individuals at high verses low genetic Obesity risk.;   The difference in neuronal activity in CNS reward and satiety circuits as represented by BOLD fMRI signal change from baseline (%) in response to food-related stimuli between lean and obese subjects with either high or low genetic Obesity risk.;   The difference within Obesity-discordant monozygotic (MZ) twin pairs regarding dietary intake;   The difference within Obesity-discordant monozygotic (MZ) twin pairs regarding physical activity level;   The difference within Obesity-discordant monozygotic (MZ) twin pairs regarding basal metabolic rate;   The difference within Obesity-discordant monozygotic (MZ) twin pairs regarding fasting circulating biomarker levels;   The difference within Obesity-discordant monozygotic (MZ) twin pairs regarding autonomic nervous system balance;   The difference between individuals at high versus those at low genetic Obesity risk regarding dietary intake;   The difference between individuals at high versus those at low genetic Obesity risk regarding physical activity level;   The difference between individuals at high versus those at low genetic Obesity risk regarding basal metabolic rate;   The difference between individuals at high versus those at low genetic Obesity risk regarding fasting circulating biomarker levels;   The difference between individuals at high versus those at low genetic Obesity risk regarding autonomic nervous system balance
5 Unknown  Does Treating Obstructive Sleep Apnea in Obese Canadian Youth Improve Blood Sugar Control?
Conditions: Obesity;   Obstructive Sleep Apnea
Intervention:
Outcome Measures: HOMA-IR;   Systemic Hypertension;   Heart rate and heart rate variability;   hsCRP;   Conners' Parent and Teacher Rating Scales;   Child Behavior Checklist;   Pediatric Quality of Life Inventory (PEDS-QL)
6 Recruiting Economic Aspects of Extreme Obesity in Adolescent
Conditions: Obesity;   Extreme Obesity
Intervention:
Outcome Measures: Economic burden of extreme Obesity in adolescents living in Germany;   Health related quality of life associated with extreme Obesity in adolescents;   BMI;   Changes in economic burden of extreme Obesity in adolescents living in Germany
7 Unknown  Sleep and Obesity in Teenagers
Condition: Obesity
Interventions: Behavioral: habitual sleep length period + extended sleep length period;   Behavioral: extended sleep length period + habitual sleep length period
Outcome Measures: The influence of sleep extension on leptin level for the obese teens group.;   Difference between the two groups (obese vs non-obese) regarding sleep length and delta waves activity.;   Study the correlation between delta waves activity and habitual sleep length;   Study the correlation between delta waves activity and psychological, behavioural, anthropometric and physiological markers of Obesity and its co morbidities
8 Recruiting Identification and Characterization of Youth With Extreme Obesity
Conditions: Obesity;   Extreme Obesity
Intervention:
Outcome Measures: Percentage of subjects that participate in the fasting blood draw;   Predictors of the acceptance of the diagnostic procedures;   Prevalence of Obesity associated psychiatric co-morbidities;   Percentage of patients that accept treatment of somatic co-morbidities;   Predictors of acceptance of treatment of co-morbidities;   Health related quality of life;   Socio-economic status;   Prevalence of Obesity associated somatic co-morbidities;   Percentage of patients that accept treatment of psychiatric co-morbidities;   Percentage of subjects that initiate a standardized low key intervention;   Percentage of subjects that participate in diagnostic procedures.
9 Recruiting Predictive Factors of Obesity-hypoventilation Syndrome (OHS) Among Obese Subjects- ETUDE COHYPOB -
Conditions: Obesity-hypoventilation Syndrome;   Nocturnal Alveolar Hypoventilation
Intervention: Other: Annual visits among 3 years. During each visit different testings are performed in order to detect an Obesity-hypoventilation syndrome (OHS)
Outcome Measure: Occurrence of Obesity-hypoventilation syndrome
10 Unknown  Virtual Environments For Supporting Obesity Treatment
Conditions: Obesity;   Morbid Obesity
Interventions: Behavioral: Experiential-Cognitive Therapy for Obesity;   Behavioral: Behavioral cognitive Treatment;   Dietary Supplement: Nutritional groups (NT)
Outcome Measures: Anxiety Inventory: State-Trait IDARE;   Body Image Questionnaire (BSQ);   Weight;   BULIT Bulimia Test;   Three Food Factors Questionnaire (TFEQ);   Opinion on exposure therapy
11 Recruiting Parents as the Agent of Change for Childhood Obesity
Condition: Obesity
Interventions: Behavioral: Parent-only Group;   Behavioral: Parent + Child Group
Outcome Measures: To evaluate the efficacy of parent-only treatment versus parent + child treatment on the body weight of the target child;   To evaluate the cost-effectiveness of parent-only treatment versus parent + child treatment;   To compare effect of parent-only treatment versus parent + child treatment on target child's and parent's dietary quality;   To compare effect of parent-only treatment versus parent + child treatment on target child's and parent's exercise behavior;   To compare effect of parent-only treatment versus parent + child treatment on target child's and parent's quality of life;   To compare effect of parent-only treatment versus parent + child treatment on target child's and parent's psychosocial measures;   To compare effect of parent-only treatment versus parent + child treatment on parent's adherence;   To compare effect of parent-only treatment versus parent + child treatment on parenting style;   To compare effect of parent-only treatment versus parent + child treatment on parent's weight loss;   To evaluate the predictors of success in childhood Obesity treatments by evaluating change in target child's and parent's weight;   To evaluate the predictors of success in childhood Obesity treatments by evaluating compliance;   To evaluate the predictors of success in childhood Obesity treatments by evaluating changes in household food environment;   To evaluate the predictors of success in childhood Obesity treatment by evaluating change in parenting style;   To evaluate the predictors of success in childhood Obesity treatment by evaluating changes in target child's and parent's psychosocial functioning
12 Recruiting Prevalence of Obesity Hypoventilation Syndrome
Condition: Obesity Hypoventilation Syndrome
Interventions: Procedure: Blood test analysis in the clinical labs;   Procedure: Pneumologist consult to establish the diagnosis of OHS
Outcome Measures: Prevalence of Obesity Hypoventilation Syndrome (OHS) in obese subjects referred to clinical laboratories for regular blood test analysis.;   Sensitivity and specificity of plasmatic [HCO3-] to detect OHS;   Prevalence of metabolic and cardiovascular comorbidities in patients with OHS;   To determine which medical specialties referred patients with OHS to clinical labs;   Incidence of serious health events at 1 and 2-year follow-up
13 Recruiting Healthy Children, Strong Families: American Indian Communities Preventing Obesity
Conditions: Obesity;   Overweight
Interventions: Behavioral: Healthy Children, Strong Families;   Behavioral: Child Safety
Outcome Measures: Change in child adiposity from baseline measured via BMI z-score;   Change in adult adiposity from baseline measured via BMI;   Change in child adiposity from baseline measured via waist circumference;   Change in adult adiposity from baseline measured via waist circumference;   Change in child fruit and vegetable consumption from baseline;   Change in adult fruit and vegetable consumption from basline;   Change in amount of child screen time from basline;   Change in amount of adult screen time from basline;   Change in amount of child physical activity from baseline;   Change in amount of adult physical activity from basline;   Change in child sleep pattern from basline;   Change in home environment from basline;   Change in adult Readiness to Change from basline;   Change in adult SF-12 scores from basline;   Stress questionnaire;   Change in adult sleep pattern from basline
14 Recruiting Observational Study of Early Metabolic and Vascular Changes in Obesity
Conditions: Understanding of Early Settings to an Obesity "Career";   Vascular Burden in Obesity;   Brown/White Adipose Tissue;   Adipokines;   Fatty Liver Disease;   Insulin Resistance
Intervention: Other: Lifestyle modification
Outcome Measures: Anthropometric changes(BMI, SAT-Topography, waist/hipCF, waist to height ratio) during intervention;   Obesity related biomarkers (fasting glucose, insulin, HOMA-index, HbA1c, liver transaminases, inflammatory markers, adipokines, clotting parameters, lipids, oxidative stress markers, Biomarkers related to tryptophan metabolism), performance diagnostics.
15 Recruiting Low-level Intervention for Adolescents With Extreme Obesity
Conditions: Obesity;   Extreme Obesity
Interventions: Behavioral: manual based low key group intervention (innovation);   Behavioral: standardized, manual based routine care
Outcome Measures: Composite primary endpoint(tested hirarchically) of a) Compliance rate and b) changes in health related quality of life.;   Changes in the 6 subscales of DISABKIDS;   Changes in quality of life;   Changes in self-esteem;   Changes in self reported time spent outside the home;   Changes in depression symptoms;   Changes in perceived stress;   Changes in the self reported attendance of school, apprenticeship, or work;   Changes in self reported physician- / and therapist contacts
16 Unknown  Increasing Cure Rate of Hepatitis C Therapy in Obese Hepatitis C Patients
Conditions: Obesity;   Insulin Resistance;   Metabolic Syndrome;   Hepatitis C
Interventions: Drug: Orlistat;   Behavioral: Dietary and Lifestyle modification educational sessions
Outcome Measures: HCV RNA;   Body weight;   waist circumference;   skin fold thickness;   HOMA, IR
17 Recruiting Brain, Obesity, Dopamine and You Study
Condition: Obesity
Intervention: Dietary Supplement: meal replacements, psychotherapy, dietary education
Outcome Measures: To determine the status of postsynaptic D2-like receptor binding in humans with Obesity.;   To determine the relationship between D2-like receptor binding, reward sensitivity and hedonic response to sweet tastes.
18 Recruiting A Pilot Study to Characterize Adipose Tissue Leukocytes by Flow Cytometry and Microscopy in Lean, Obese and Psoriatic Subjects (Lean/Obese)
Conditions: Healthy Volunteers;   Psoriasis;   Obesity
Intervention: Procedure: Adipose tissue biopsy (fat biopsy)
Outcome Measure: Biomarkers for phenotyping a new type of leukocyte
19 Unknown  Evaluation of Intestinal Microbiome in Obese Kids
Conditions: Obesity;   Non-Alcoholic Fatty Liver Disease
Interventions: Other: Blood Draw;   Other: Stool collection;   Other: BodPod Measurement;   Other: Liver Ultrasound
Outcome Measures: Alterations in the intestinal microbiome are associated with increased immune activation and progression of Obesity associated NAFLD.;   Characterize the intestinal microbiome through quantitative analysis of stool samples in participants with Obesity and those with Obesity and NAFLD.;   Characterize inflammatory markers of participants with Obesity versus those obese participants that also have NAFLD.
20 Unknown  Trial of the MEND Childhood Obesity Treatment Program
Condition: Obesity
Interventions: Behavioral: MEND Childhood Obesity Program;   Behavioral: Control Group
Outcome Measures: Body Mass Index z-score;   Body fat, waist circumference, blood pressure, arterial stiffness, heart rate control, fitness, physical activity and sedentary behaviour status, self esteem and health related quality of life.