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OFF LABEL USE and Endocet

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OFF LABEL USE Symptoms and Causes

Normally, your cells grow and die in a controlled way. Cancer cells keep growing without control. Chemotherapy is drug therapy for cancer. It works by killing the cancer cells, stopping them from spreading, or slowing their growth. However, it can also harm healthy cells, which causes side effects.

You may have a lot of side effects, some, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts. Some common side effects are fatigue, nausea, vomiting, pain, and hair loss. There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemotherapy is over, so most side effects gradually go away.

Your treatment plan will depend on the cancer type, the chemotherapy drugs used, the treatment goal, and how your body responds. Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells. You might take the drugs by mouth, in a shot, as a cream, or intravenously (by IV).

NIH: National Cancer Institute

Check out the latest treatments for OFF LABEL USE

OFF LABEL USE treatment research studies

Endocet clinical trials, surveys and public health registries


Find Drug Side Effect reports



Endocet Side Effects

Nausea (11)
Abdominal Pain Upper (7)
Diarrhoea (6)
Asthenia (5)
Abdominal Discomfort (5)
Insomnia (5)
Loss Of Consciousness (5)
Pruritus (5)
Vomiting (5)
Dizziness (4)
Decreased Appetite (4)
Fatigue (4)
Product Substitution Issue (4)
Headache (4)
Pain (4)
Feeling Jittery (3)
Constipation (3)
Hyperhidrosis (3)
Anxiety (3)
Migraine (3)
Malaise (3)
Renal Pain (3)
Somnolence (3)
Overdose (3)
Weight Increased (2)
Abdominal Distension (2)
Influenza (2)
Lethargy (2)
Abdominal Pain (2)
Local Swelling (2)
Chest Pain (2)
Crying (2)
Vision Blurred (2)
Convulsion (2)
Contusion (2)
Bronchopneumonia (2)
Arthralgia (2)
Panic Attack (2)
Mood Swings (2)
Memory Impairment (2)
Myocardial Infarction (2)
Nightmare (2)
Pain In Extremity (2)
Pharyngeal Oedema (2)
Product Formulation Issue (2)
Restlessness (2)
Rash (2)
Pyrexia (2)
Product Quality Issue (2)
Urticaria (2)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

45 yr old male, went to dentist had a lot of calc buildup, gave me peridex, told me it might be a little strong might need to cut it down or test it first, he gave this to me, I didnt read the label or anything I thought it was just a mouthwash WARNI

Anthony, thank you. I thought I was going nuts. Weight gain would be an understatement. Bloating and gas too. Not sure I want to continue this and I have not been on the 'full' dose --- misread the label and am happy I d

Hi i need information toward somatropin label price?

I had a devastating experience with this drug. I had been using Flexeril for back and neck pain but found it no longer as effective. I asked my doctor if there was something stronger. He prescribed Baclofen. Having not read the label carefully, m

I have been on 20 mg of Cipralex for over 3 years. It does it's job and I do not experience anxiety. In doing your homework, you will see Cipralex is for anxiety which is part of the 'depression' family. One does not label the other. One of the bigg

I have been sick with allergies/asthma/sinusitis for over a week and when I took Mucinex DM I made sure to read the label carefully. My carton said to take 1 every 12 hours and no more than 2 in 24 hours. After taking the first pill it had no effect

I haven't had an abortion induced but the medicine label clearly states to use two forms of protection. If the patient has unprotected sex, that the patient's problem. Every doctor visit my doctor stressed to me how much the medicine could

I may try Lyrica off label for GAD and PD as well as some antidepressive effects I read in journals, articles. Lyrica has been approved for GAD in Europe but hasn't gotten the FDA approval for it here yet. The above poster, Case Report #Self-49

I take Centrum Silver and wanted a label that I could read.

Is a GG 40 with a Sandoz label made in a different laboratory than a GG 40 with a Geneva label? (I know they are both 10 mg of amitriptyline.) Thank you. Appreciate reply as soon as possible.

OFF LABEL USE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Efficacy and Safety of Amantadine HCl Extended Release Tablets in Parkinson's Disease Subjects With Levodopa-Induced Dyskinesias
Conditions: Parkinson's Disease;   Levodopa Induced Dyskinesia (LID)
Interventions: Drug: Amantadine HCl ER (ALLAY-LID II);   Drug: Placebo
Outcome Measures: Unified Dyskinesia Rating Scale;   Mobility State Self Assessment (Subject Diary Cards);   Mobility State Self-Assessment (Subject Diary Cards);   MDS-Unified Parkinson's Disease Rating Scale;   Fatigue Severity Scale
2 Not yet recruiting Efficacy and Safety of Amantadine ER Tablets to Treat Parkinson's Disease Patients With Levodopa Induced Dyskinesia.
Conditions: Parkinson's Disease;   Levodopa Induced Dyskinesia (LID)
Interventions: Drug: Amantadine ER Tablets;   Drug: Placebo Tablets for Amantadine ER Tablets
Outcome Measures: Unified Dyskinesia Rating Scale (UDysRS);   Mobility State Self-Assessment (Subject Diary Cards);   MDS-UPDRS;   Fatigue Severity Scale
3 Recruiting Phase III Study of the Safety and Efficacy of Cl-108 in the Treatment of Moderate to Severe Pain
Conditions: Pain;   Nausea;   Vomiting
Interventions: Drug: CL-108;   Drug: Placebo
Outcome Measures: To compare the occurrence and severity of opioid-induced nausea and vomiting (OINV) associated with CL-108 to Norco.;   To demonstrate the efficacy of CL-108 when compared to placebo for the relief of pain following surgical removal of impacted third molar teeth.;   Reduction of the severity of nausea in patients treated with an opioid-containing pain reliever.;   Reduction of vomiting in patients treated with an opioid-containing pain reliever.
4 Recruiting Edible Plant Exosome Ability to Prevent Oral Mucositis Associated With Chemoradiation Treatment of Head and Neck Cancer
Conditions: Head and Neck Cancer;   Oral Mucositis
Interventions: Dietary Supplement: Grape extract;   Drug: Lortab, Fentanyl patch, mouthwash
Outcome Measures: Pain caused by oral mucositis;   Level of immune biomarkers in blood;   Level of immune biomarkers in mucosal tissue
5 Not yet recruiting Ureteral Stent-related Pain and Mirabegron (SPAM) Trial
Condition: Nephrolithiasis
Interventions: Drug: Mirabegron;   Drug: Tamsulosin;   Drug: Percocet
Outcome Measures: Ureteral stent related pain and lower urinary tract symptoms (LUTS) as measured by the Ureteral Stent Symptom Questionnaire.;   Quality of life impact of mirabegron for stent symptoms as measured with the Ureteral Stent Symptoms Questionnaire.
6 Unknown  Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain
Condition: Pain, Fracture, Sprain
Interventions: Drug: Fentanyl rapid dissolving tablet 100mcg;   Drug: lansoprazole 15mg rapidly dissolving tablet + Percocet PO
Outcome Measures: Time to analgesia;   Occurrence of untoward opioid side effects
7 Not yet recruiting An Open Label, Prospective Study of the Analgesic Efficacy of Oral Xartemis Compared to Generic Oxycodone/APAP( Acetaminophen) in the Treatment of Moderate to Severe Post Operative Pain.
Condition: Post Operative Pain
Interventions: Drug: Percocet;   Drug: Xartemis
Outcome Measures: Non Inferiority;   Patient Global Assessment
8 Recruiting Adductor Canal Nerve Block Following Total Knee Arthroplasty
Condition: Post-op Pain
Interventions: Drug: Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed.;   Drug: For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA.
Outcome Measures: Total Opiate pain medication;   Patient satisfaction with pain control
9 Recruiting Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (AATD)
Conditions: Liver Fibrosis;   Alpha-1 Antitrypsin Deficiency;   AAT Deficiency;   AATD
Interventions: Device: Abdominal ultrasound;   Procedure: History and physical;   Procedure: Intravenous catheter;   Procedure: Blood draw;   Other: Liver questionnaire;   Procedure: Liver Biopsy;   Drug: Midazolam;   Drug: Fentanyl;   Drug: Lidocaine;   Drug: Acetaminophen;   Drug: Lorazepam;   Drug: Oxycodone/Acetaminophen;   Drug: Ondansetron
Outcome Measures: To estimate the prevalence and histologic spectrum of liver injury in an adult with Alpha-1 Antitrypsin deficiency and a genotype of ZZ.;   To identify environmental and host risk factors for clinically significant liver fibrosis.;   To define the diagnostic accuracy of non-invasive markers of fibrosis in AAT liver disease.;   To explore epigenetic markers for the development of liver fibrosis.;   To quantify liver fibrosis progression.
10 Not yet recruiting The Effect of NSAIDs After a Rotator Cuff Repair Surgery.
Condition: Rotator Cuff Tear
Interventions: Procedure: Rotator cuff repair;   Drug: Ibuprofen, Hydrocodone/Acetaminophen, Omeprazole;   Drug: Hydrocodone/Acetaminophen
Outcome Measures: American Shoulder and Elbow Surgeons (ASES) Shoulder Score;   Ultrasound evaluation of retear rate
11 Recruiting Safety and Efficacy Study of Fentanyl Buccal Tablet Use in the Emergency Department for Isolated Extremity Injury
Condition: Pain
Interventions: Drug: Fentanyl;   Drug: Oxycodone/acetaminophen;   Drug: oxycodone/acetaminophen
Outcome Measures: Pain Level;   Nausea level;   Occurrence of adverse events
12 Recruiting Comparing the Efficacy of Oral Opioids for Outpatient Acute Pain Management After ED Discharge Discharge
Condition: Analgesia After ED Discharge for Extremity Injuries
Intervention: Drug: Oral Opioid Pain Medicine
Outcome Measures: Difference in pain score before and after last dose.;   Overall Satisfaction with the pain medicine;   Side Effects
13 Recruiting Safety and Efficacy of Gabapentin for Neuropathic Pain in Fabry Disease
Conditions: Fabry Disease;   Neuropathic Pain
Interventions: Drug: Gabapentin;   Drug: placebo
Outcome Measures: average reduction in hydrocodone-acetaminophen use;   Number and type of adverse events;   Pain levels;   Define therapeutic level for gabapentin
14 Not yet recruiting Equality Study of Ofirmev vs Oral Acetaminophen
Condition: Pain, Postoperative
Interventions: Drug: IV acetaminophen;   Drug: oral acetaminophen
Outcome Measures: Primary outcome will measure total opioid consumption while the patient is in the PACU;   time from PACU admission to request for first opioid dose
15 Not yet recruiting Local Anesthesia and Analgesics in Endodontic Pain
Condition: Odontalgia
Interventions: Drug: Oral placebo;   Drug: Oral ibuprofen;   Drug: oral naproxen;   Drug: oral acetaminophen/hydrocodone + ibuprofen
Outcome Measures: Effect of long acting anesthesia and analgesics on endodontic pain;   Effect of gender and age on post-operative endodontic pain treatment
16 Recruiting Clinical Research of the Prognostic Influence of NSAIDS's Anti-inflammatory Effect on Senior Patients With Hip Fracture
Condition: Hip Fracture
Interventions: Drug: celecoxib;   Drug: Acetaminophen oxycodone
Outcome Measure:
17 Recruiting Tracking & Feedback Registry to Reduce Breast Cancer Treatment Disparities
Condition: Breast Cancer
Intervention: Other: Tracking & Feedback
Outcome Measures: Change in intervention effect of adjuvant treatment;   Organizational Characteristics
18 Not yet recruiting Post-operative Analgesia in Elective, Soft-tissue Hand Surgery
Conditions: Carpal Tunnel;   Ganglion Cyst;   Trigger Finger
Interventions: Drug: Acetaminophen/Hydrocodone;   Drug: Acetaminophen/Ibuprofen
Outcome Measures: Efficacy comparison utilizing Visual Analog Scale (VAS), Likert Pain Score and Mean daily pain values;   Incidence of adverse effects
19 Recruiting Narcotic vs. Non-narcotic Pain Study Protocol
Condition: Carpal Tunnel
Interventions: Drug: Narcotic;   Drug: non-narcotic
Outcome Measure: Pain relief
20 Not yet recruiting Comprehensive Opioid Management
Condition: Chronic Pain
Interventions: Behavioral: IVR self-management;   Behavioral: Opioid monitoring;   Other: Enhanced usual care
Outcome Measures: Brief Pain Inventory;   Concordance with opioid treatment practice guidelines