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OFF LABEL USE and Valium

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OFF LABEL USE Symptoms and Causes

Normally, your cells grow and die in a controlled way. Cancer cells keep growing without control. Chemotherapy is drug therapy for cancer. It works by killing the cancer cells, stopping them from spreading, or slowing their growth. However, it can also harm healthy cells, which causes side effects.

You may have a lot of side effects, some, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts. Some common side effects are fatigue, nausea, vomiting, pain, and hair loss. There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemotherapy is over, so most side effects gradually go away.

Your treatment plan will depend on the cancer type, the chemotherapy drugs used, the treatment goal, and how your body responds. Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells. You might take the drugs by mouth, in a shot, as a cream, or intravenously (by IV).

NIH: National Cancer Institute

Check out the latest treatments for OFF LABEL USE

OFF LABEL USE treatment research studies

Valium clinical trials, surveys and public health registries


Find Drug Side Effect reports



Valium Side Effects

Overdose (59)
Somnolence (59)
Death (48)
Anxiety (44)
Coma (42)
Confusional State (39)
Suicide Attempt (37)
Insomnia (36)
Nausea (33)
Fall (30)
Headache (29)
Pain (28)
Depression (28)
Dyspnoea (28)
Fatigue (26)
Malaise (25)
Convulsion (25)
Agitation (23)
Tremor (21)
Vomiting (20)
Toxicity To Various Agents (18)
Dizziness (18)
Hypotension (18)
Suicidal Ideation (16)
Completed Suicide (16)
Diarrhoea (16)
Pulmonary Embolism (15)
Hypertension (14)
Intentional Overdose (14)
Chest Pain (14)
Asthenia (14)
Loss Of Consciousness (14)
Respiratory Depression (13)
Weight Decreased (13)
Amnesia (13)
Pyrexia (13)
Road Traffic Accident (13)
Sopor (13)
Depressed Level Of Consciousness (13)
Arthralgia (13)
Feeling Abnormal (13)
Injury (12)
Accidental Overdose (12)
Bradycardia (11)
Dysarthria (11)
Diabetes Mellitus (11)
Sedation (11)
Respiratory Failure (11)
Oedema Peripheral (11)
Hallucination (11)

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Common Meds

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Cipro (8580)
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Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
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Neurontin (6501)
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Recent Reviews

A women took 17 pils of entumin now she is restless

45 yr old male, went to dentist had a lot of calc buildup, gave me peridex, told me it might be a little strong might need to cut it down or test it first, he gave this to me, I didnt read the label or anything I thought it was just a mouthwash WARNI

Anthony, thank you. I thought I was going nuts. Weight gain would be an understatement. Bloating and gas too. Not sure I want to continue this and I have not been on the 'full' dose --- misread the label and am happy I d

Hi i need information toward somatropin label price?

I had a devastating experience with this drug. I had been using Flexeril for back and neck pain but found it no longer as effective. I asked my doctor if there was something stronger. He prescribed Baclofen. Having not read the label carefully, m

I have been on 20 mg of Cipralex for over 3 years. It does it's job and I do not experience anxiety. In doing your homework, you will see Cipralex is for anxiety which is part of the 'depression' family. One does not label the other. One of the bigg

I have been sick with allergies/asthma/sinusitis for over a week and when I took Mucinex DM I made sure to read the label carefully. My carton said to take 1 every 12 hours and no more than 2 in 24 hours. After taking the first pill it had no effect

I haven't had an abortion induced but the medicine label clearly states to use two forms of protection. If the patient has unprotected sex, that the patient's problem. Every doctor visit my doctor stressed to me how much the medicine could

I may try Lyrica off label for GAD and PD as well as some antidepressive effects I read in journals, articles. Lyrica has been approved for GAD in Europe but hasn't gotten the FDA approval for it here yet. The above poster, Case Report #Self-49

I take Centrum Silver and wanted a label that I could read.

Is a GG 40 with a Sandoz label made in a different laboratory than a GG 40 with a Geneva label? (I know they are both 10 mg of amitriptyline.) Thank you. Appreciate reply as soon as possible.

OFF LABEL USE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Comparison of Absorption of Vaginal Diazepam Using Different Delivery Systems
Condition: Metabolism, Drug
Interventions: Drug: Diazepam tablet, 5 mg, vaginal;   Drug: Diazepam Suppository, 5 mg, vaginal;   Drug: Diazepam Cream, 5 mg, Vaginal
Outcome Measures: Serum diazepam levels measured over time;   Side effects observed with each of three types of vaginal diazepam
2 Recruiting Vaginal Diazepam for the Treatment of Female Pelvic Pain
Conditions: Pelvic Floor Disorders;   Pelvic Pain
Interventions: Drug: Diazepam;   Drug: Placebo
Outcome Measures: Change from baseline in Visual Analog Pain Scale score at 4 weeks, 12 weeks, and 24 weeks.;   Change from baseline in Pelvic Floor Distress Inventory-20 Questionnaire score at 4 weeks, 12 weeks, and 24 weeks.;   Change from baseline in McGill Pain Questionnaire score at 4 weeks, 12 weeks, and 24 weeks.;   Change from baseline in Global Response Assessment score at 4 weeks, 12 weeks, and 24 weeks.
3 Recruiting Lofexidine for Inpatient Opiate Detox in Singapore
Condition: Opiate Dependent Patients Who Are Undergoing Inpatient Detoxification in Singapore
Interventions: Drug: Lofexidine;   Drug: Diazepam;   Drug: Placebo for Lofexidine;   Drug: Placebo for Diazepam
Outcome Measures: To evaluate differences in OOWS (Objective Opiate Withdrawal Scale);   To evaluate differences in SOWS (Short Opiate Withdrawal Scale);   To evaluate differences in pupil sizes;   To evaluate differences in craving on the Visual Analogue Scale;   To evaluate differences in time to drop-out (length of stay on the ward);   To evaluate differences in emotional/psychological symptoms
4 Unknown  Performance Study of the SOLO 2.0 Insulin Pump
Condition: Type 1 Diabetes
Intervention: Device: SOLO insulin pump
Outcome Measures: Device related safety issues;   SOLO use errors;   Device-related adverse outcome;   Diabetes-related adverse outcome;   Satisfaction iwth SOLO;   Product quality (MTBF)
5 Recruiting A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction
Condition: Post-operative Pain
Interventions: Drug: Bupivacaine;   Drug: Botulinum Toxins;   Drug: Analgesics
Outcome Measure: Pain Score Questionnaire
6 Recruiting Safety and Feasibility Study of Enhanced Recovery in Pancreaticoduodenectomy
Condition: Pancreaticoduodenectomy (E04.210.760)
Interventions: Behavioral: Enhanced recovery after surgery protocol;   Procedure: Standard perioperative care;   Drug: PONV prophylaxis with Ondansetron + Dexamethasone;   Other: Postoperative mobilization program;   Drug: Epidural analgesia with naropin + sufentanil;   Drug: Pre-anesthetic medication with diazepam;   Behavioral: Preadmission counselling;   Drug: Preoperative bowel preparation with sodium phosphate
Outcome Measures: Adherence to the pathway;   Postoperative outcome
7 Recruiting Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental Disability
Condition: Dental Care for Disabled
Interventions: Drug: Midazolam Mylan;   Drug: Lorazepam Mylan;   Drug: Valium + Akineton + Dehydrobenzperidol + Atropine sulfate
Outcome Measures: Level of cooperation of patient when receiving regular dental care;   Recording of vital parameters during regular dental care delivery;   Level of patient comfort and possible side-effects after dental treatment session
8 Recruiting The PROOF Study: The PICC Related Obstruction Of Flow Study
Condition: Patients Indicated for a PICC for Any Medical Condition
Interventions: Device: BioFlo™ Peripherally Inserted Central Catheter (PICC);   Device: Bard® Dual-Lumen PowerPICC SOLO2®
Outcome Measures: Incidence of catheter-related venous thrombosis as confirmed by diagnostic ultrasound;   Incidence of other catheter-related complications
9 Not yet recruiting Implementing Health Plan-Level Care Management for Solo & Small Practices
Conditions: Bipolar Disorder;   Depression
Interventions: Behavioral: Chronic Care Model for Mood Disorders;   Other: Educational Control
Outcome Measures: Quality of Life;   Reduced Mood Disorder Symptoms;   Improved Guideline-Concordant Care;   Reduced Hospitalizations;   Improved Work Productivity
10 Unknown  Positron Emission Mammography (PEM) Flex Solo II Positron Emission Tomography (PET) Scanner and Stereo Navigator Biopsy Accessory for the Diagnosis of Breast Cancer
Condition: Breast Cancer
Intervention: Procedure: PEM Breast Biopsy
Outcome Measures: Evidence that breast biopsy can be performed using PEM and Stereo Navigator software;   Evidence that breast biopsy can be performed in less clinical visits than if biopsy is performed using MRI, mammogram, and/or ultrasound
11 Recruiting Perioperative Δ9-THC for Postsurgical Pain
Condition: Pain
Interventions: Drug: Namisol;   Drug: Diazepam/placebo
Outcome Measures: Analgesic efficacy;   Incidence of persistent continuous or intermittent postsurgical abdominal pain
12 Unknown  The Effect of Prescription Medications in Marijuana Users
Condition: Marijuana Abuse
Intervention: Drug: bupropion, diazepam, dronabinol, ramelteon (Investigational Drug)
Outcome Measures: marijuana withdrawal;   subjective effects of smoked marijuana;   cognitive performance
13 Recruiting Tolerance of PICC Line Versus Implanted Port for Adjuvant Chemotherapy in Early Breast Cancer
Condition: Early Stage Breast Carcinoma
Interventions: Device: implanted port for chemo administration (X-port isp);   Device: Use of a PICC line for chemo administration (PowerPICC SOLO²)
Outcome Measures: Probability of occurrence of a significant adverse event related to the central venous device;   Patients' satisfaction for the use of their central venous device
14 Unknown  Quality of Sleep in Patients With Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Intervention: Drug: diazepam, melatonin
Outcome Measure:
15 Unknown  Continuation Electroconvulsive Therapy (C-ECT) for Relapse Prevention in Major Depression
Condition: Depression
Interventions: Device: Thrymatron System IV device (CONSOLIDATION ELECTROCONVUsLIVE THERAPY) plus PHARMACOTHERAPY;   Drug: PHARMACOTHERAPY
Outcome Measures: Hamilton Depression Rating Scale 21 items (HDRS-21);   Mini-Mental State Examination (MMSE 35);   UKU - Adverse effects rating scales;   Demographical Data Memory (MEDABI-20);   Rey Figure;   Trail Making Test A;   Trail Making Test B;   Stroop Test;   Direct and inverse digits (WAIS, Weschler Adults Intelligence Sacle).;   Vocabulary WAIS (Weschler Adults Intelligence Scale);   Frequency Hospitalization Quotient;   Hospital Day Quotient (HDQ)
16 Recruiting RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
Condition: Respiratory Insufficiency
Interventions: Device: Vibrating Mesh Nebulizer Arm;   Device: Jet Nebulizer Arm
Outcome Measures: Venilator Associated Events;   Bacterial Count and type;   Length of Stay in Intensive Care Unit;   Days on Mechanical Ventilation;   Ventilator-Associated Tracheobronchitis
17 Recruiting Gabapentin Treatment of Benzodiazepine Dependence
Condition: Benzodiazepine Dependence
Interventions: Drug: gabapentin;   Drug: Placebo
Outcome Measure: Abstinence from Benzodiazepine use
18 Unknown  Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
Condition: Spastic Cerebral Palsy
Interventions: Drug: Extended-release Epidural morphine (EREM) 80;   Drug: Extended-release Epidural Morphine (EREM) 120;   Drug: Control: Saline
Outcome Measures: Quantity of fentanyl administered;   Adequacy of analgesia as judged by age-adjusted pain scales.;   Incidence of respiratory depression;   Hemodynamic instability;   Rate of CSF leak;   Rate of infection;   Urinary retention;   Nausea and/or vomiting;   Pruritis
19 Recruiting Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment
Condition: Electrical Status Epilepticus in Sleep
Intervention: Drug: ESES treated with clobazam
Outcome Measures: Cognitive ability;   Language;   Executive function;   Adaptive/development skills;   Behavior;   Interictal epileptiform activity
20 Recruiting Pharmacokinetics of Nebulized Amikacin in Non Invasive Ventilated Healthy Volunteers.
Conditions: Acute Respiratory Insufficiency;   Chronic Respiratory Insufficiency;   Bronchospasm and Obstruction
Intervention: Device: Nebulizer
Outcome Measure: Pharmacokinetics of nebulized amikacin