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OPEN REDUCTION OF FRACTURE and FOSAMAX

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OPEN REDUCTION OF FRACTURE Symptoms and Causes

A fracture is a break, usually in a bone. If the broken bone punctures the skin, it is called an open or compound fracture. Fractures commonly happen because of car accidents, falls, or sports injuries. Other causes are low bone density and osteoporosis, which cause weakening of the bones. Overuse can cause stress fractures, which are very small cracks in the bone.

Symptoms of a fracture are

  • Intense pain
  • Deformity - the limb looks out of place
  • Swelling, bruising, or tenderness around the injury
  • Numbness and tingling
  • Problems moving a limb

You need to get medical care right away for any fracture. An x-ray can tell if your bone is broken. You may need to wear a cast or splint. Sometimes you need surgery to put in plates, pins or screws to keep the bone in place.

Check out the latest treatments for OPEN REDUCTION OF FRACTURE

OPEN REDUCTION OF FRACTURE treatment research studies

FOSAMAX clinical trials, surveys and public health registries


Find Drug Side Effect reports



FOSAMAX Side Effects

Femur Fracture (5674)
Anxiety (3177)
Osteonecrosis (2820)
Fall (2638)
Depression (2384)
Arthralgia (1887)
Dental Caries (1636)
Arthropathy (1621)
Back Pain (1566)
Low Turnover Osteopathy (1355)
Anaemia (1283)
Osteomyelitis (1270)
Hypertension (1242)
Blood Cholesterol Increased (1236)
Impaired Healing (1123)
Abscess (1121)
Adverse Event (1103)
Bone Density Decreased (1051)
Bone Disorder (1050)
Chest Pain (1022)
Bronchitis (915)
Tooth Disorder (890)
Arthritis (849)
Gastrooesophageal Reflux Disease (838)
Intramedullary Rod Insertion (835)
Osteonecrosis Of Jaw (834)
Cataract (805)
Osteoarthritis (784)
Osteoporosis (749)
Pain In Extremity (719)
Stress Fracture (715)
Jaw Disorder (708)
Asthma (706)
Cellulitis (697)
Chronic Obstructive Pulmonary Disease (679)
Abdominal Pain (632)
Diarrhoea (584)
Asthenia (582)
Constipation (557)
Bursitis (552)
Atrial Fibrillation (550)
Pain (544)
Exostosis (531)
Fatigue (522)
Oral Infection (505)
Carpal Tunnel Syndrome (503)
Dizziness (502)
Foot Fracture (501)
Hip Fracture (497)
Headache (477)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

After being on Fosamax for approximately four and one half years suddenly I developed severe medial bilateral knee pain. Have pain when walking down and up stairs. I have NO history of arthritis, no inflammation or redness at the location of pain. I

Can Fosamax cause a drop in blood pressure? Can it worsen pre-existing anaemia. I've taken 4 weekly 70mg tablets and am feeling dizzy and week with loss of sensation in my fingers and joint pains. As I have suffered a year ago from kidney failure

Critical hypertension

Does fosamax affect on teeth cause a major concern. I need it for my bones,but want to keep my teeth!

I feel swollen and feel fatter since starting Fosamax.Weight gain is maybe three lbs but eyes are puffy and face seems swollen. I plan to see my doctor this week. I don't want my osteoporosist to get worse so will most likely stay on it but a diureti

I have been using fosamax for years for osteopenia. I have good teeth with1 root canal. I am wooried about it affecting my teeth. Is taking it a major risk for teeth? Is there a better way to prevent bone loss? I am 64, good health and use weight tra

I have had gastric bypas and would like to know if I can take Fosamax.

I started generic fosamax 10 days ago . After my first dose( sunday)I was fine, but the day after (Monday) in the afternoon I experienced crushing pain in my upper spine that radiated to the front. I had severe difficulty rising f

I took Actonel for 2 months and the psorasis in my scalp got out of control. My Doctor could find no connection. I have been on Fosamax for one month now and the same thing is happening. Have there been other reports of this side effect?

I've heard that it's worse for the bones in the head (teeth, jaw bones, etc.) than anywhere in the body). I'm sure there are exceptions and people who get along fine, but there are WAY too many cases to chance it!

48YO male, obese, diabetic, hypertensive, mild anxiety and depression. R BKA, R Acetabula fracture 13 years ago from motorcycle accident. Swollen gall bladder removed during hospitalization. Current meds include Metformin (withheld pre- and post- ct)

A child has age two years and he got fracture in his left leg which is minor and Doctor has advised that child should take Brufen syrup for pain if he feel. My question is that child (2 years old) do urine without any indication to her mother and

A few weeks ago I went to see the doctor because my hand was so swollen that I could not open them in the morning. I take metformin as well and now my fingers have swelled and they have turned a bit of purplish in color now the color has faded and my

After taking the Clindamycin Capsules, I have nausea then it feels as if my chest is about to burst open, like i am about to choke which lasts at least 3 hours. I never felt like this in my life. Help!

Barry I also suffer upset stomach and stomach pain that lasts for several days. In my view this product should not be sold on the open market.

Blurred vision and reduction in vision acuity in the affected eye

Child got the fracture in his left leg, and Doctor advised to give him the Brufen as pain killer but he is not telling about his urine, whats the problem behind this situation?

Excellent. Used a tube of ceam which actually expired 7+ years ago and the skin on my fingers, which had open 'cuts' along the finger print lines were normal after about 7 days use.

Extreme allergic reaction. Could not open eyes due to swelling. Three days of huge welts all over body. Pressure points had large welts on elbows, knees and buttocks. The only way to get rid of them was constant application of cooling compresses. &am

Feet swollen 3x size.. not supposed to take lasix or K with this med , which I had been prescribed to do...Feet felt as if they would split open.......................HELP ME ......<a href='mailto:......mamselle1930jem@aol.com'>mamselle1930jem@

OPEN REDUCTION OF FRACTURE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting The Effect of Alendronate on the Immune Response to Hepatitis B Vaccine in Healthy Adults
Condition: Healthy Volunteers
Interventions: Drug: Alendronate;   Drug: Hepatitis B Vaccine;   Drug: Placebo
Outcome Measures: Safety/Adverse events;   Efficacy
2 Recruiting Testosterone and Alendronate in Hypogonadal Men
Conditions: Hypogonadism;   Osteopenia;   Osteoporosis
Interventions: Drug: Testosterone;   Drug: Alendronate;   Drug: Placebo Alendronate;   Drug: Placebo Testosterone
Outcome Measure: Spine Bone Mineral Density by DXA
3 Unknown  Alendronate for Vascular Calcification in Peritoneal Dialysis Patients?
Condition: Peritoneal Dialysis
Intervention: Drug: alendronate (Fosamax)
Outcome Measures: 1.Changes of calcification score of coronary arteries and aorta;   2.Changes of bone density;   changes of parathyroid hormone;   changes of serum calcium and phosphate level;   changes of C reactive protein;   changes of lipid profile;   adverse reactions
4 Unknown  Fosamax for Childhood Cancer Survivors
Condition: Osteoporosis
Interventions: Drug: Alendronate;   Drug: Placebo
Outcome Measures: The percent change in bone mineral density (BMD) at lumbar spine at 36-weeks in subjects who receive active and control treatments;   Changes in BMD at femoral neck;   Changes in biochemical markers of bone turnover;   Occurrence of clinical bone-related symptoms at 12-weeks and end of this study
5 Not yet recruiting RA Denosumab on Bone Microstructure Study
Condition: Rheumatoid Arthritis
Interventions: Drug: Denosumab;   Drug: Alendronate
Outcome Measures: Changes from baseline in bone volumetric density at distal radius at 6th month;   Changes from baseline in trabecular bone microarchitecture at distal radius at 6th month;   Changes from baseline in bone volumetric density at the 2nd metacarpal bone at 6th month;   Changes from baseline in trabecular bone microarchitecture at 2nd metacarpal bone at 6th month;   Changes from baseline in areal bone density at total hip at 6th month;   Changes from baseline in areal bone density at lumbar spine at 6th month;   Changes in areal bone density at distal radius at 6th month;   Changes from baseline in bone volumetric density at distal radius at 3rd month;   Changes from baseline in trabecular bone microarchitecture at distal radius at 3rd month;   Changes from baseline in bone volumetric density at the 2nd metacarpal bone at 3rd month;   Changes from baseline in trabecular bone microarchitecture at 2nd metacarpal bone at 3rd month;   Changes from baseline in areal bone density at total hip at 3rd month;   Changes from baseline in areal bone density at lumbar spine at 3rd month;   Changes in areal bone density at distal radius at 3rd month
6 Recruiting Study to Determine the Efficacy and Safety of Romosozumab in the Treatment of Postmenopausal Women With Osteoporosis
Condition: Postmenopausal Women With Osteoporosis
Interventions: Drug: Romosozumab;   Drug: Alendronate
Outcome Measures: Incidence of clinical fracture;   Incidence of new vertebral fracture;   Incidence of fracture;   Percent changes in DXA Bone Mineral Density from baseline to 12 months;   Percent changes in DXA Bone Mineral Density from baseline to 24 months;   Percent changes in DXA Bone Mineral Density from baseline to 36 months
7 Not yet recruiting Bone Antiresorptive Therapy With Antiretroviral Initiation (BATARI) Pilot Trial
Condition: HIV
Intervention: Drug: alendronate/vitamin D
Outcome Measures: Percentage changes in BMD at a) the lumbar spine and b) proximal femur;   Feasibility;   Acceptability;   Safety/Tolerability;   Adherence;   Bone Biomarkers
8 Not yet recruiting Study Investigating the Effect of Drugs Used to Treat Osteoporosis on the Progression of Calcific Aortic Stenosis.
Condition: Calcific Aortic Stenosis
Interventions: Drug: Denosumab;   Drug: Alendronic Acid;   Drug: Denosumab Placebo;   Drug: Alendronic Acid Placebo
Outcome Measures: Change in aortic valve calcium score;   Change in aortic valve 18F-NaF uptake;   Change in aortic-jet velocity;   Change in thoracic aortic and coronary artery calcium score;   Change in thoracic spine bone mineral density;   Change in quality of life determined by Short Form 36 Questionnaire
9 Recruiting Comparison of the Effect of an Ongoing Treatment With Alendronate or a Drug Holiday on the Fracture Risk in Osteoporotic Patients With Bisphosphonate Long Term Therapy
Condition: Osteoporosis
Interventions: Drug: Alendronate;   Drug: Placebo
Outcome Measures: Incidence of new osteoporotic fractures;   Equivalence of deaths with and without continued bisphosphonate therapy;   Incidence of the combination of fractures and deaths
10 Recruiting Bone Healing After Dental Extraction in Postmenopausal Osteoporotic Women Treated With Alendronate Per os Weekly
Condition: Alveolar Bone Healing After Dental Extraction
Intervention: Procedure: Dental extraction
Outcome Measures: Alveolar socket filled by new bone;   Mucosal injury
11 Unknown  The Study of the Early Administration of Alendronate on Prevention of Bone Loss After Hip Fracture.
Condition: Osteoporosis
Intervention: Drug: Alendronate
Outcome Measure:
12 Unknown  Osteoporosis and Dental Implant
Condition: Osteoporosis
Interventions: Drug: alendronate once weekly 70mg;   Drug: placebo
Outcome Measure: Dental CT
13 Unknown  Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis
Conditions: Osteoporosis;   Cystic Fibrosis
Interventions: Drug: alendronate sodium;   Drug: calcium carbonate;   Drug: cholecalciferol
Outcome Measure:
14 Unknown  Phase II Randomized Study of Alendronate Sodium for Osteopenia in Patients With Gaucher's Disease
Conditions: Gaucher's Disease;   Osteopenia
Interventions: Drug: alendronate sodium;   Drug: calcium carbonate;   Drug: cholecalciferol
Outcome Measure:
15 Unknown  Pharmacokinetics of Maxmarvil® in Healthy Postmenopausal Women
Condition: Osteoporosis
Intervention: Drug: Maxmarvil®
Outcome Measure: analysis of Alendronate concentrate
16 Recruiting Stem Cell Recruitment in Osteoporosis Therapy
Condition: Low Bone Density
Interventions: Drug: Teriparatide;   Drug: Alendronate;   Dietary Supplement: calcium and vitamin D
Outcome Measures: Number of Stro-1+ MSCs at bone resorption sites in bone biopsies of subjects treated with PTH or ALN.;   Number of p-Smad 2/3+ cells/mm2 at active resorption sites on bone biopsy specimens of subjects treated with PTH or ALN.;   The percent increase in Stro-1+/CD146+ cells in the blood before and after treatment with PTH or ALN.;   Number of human Stro-1+ MSCs at bone resorption sites in bone of Rag2-/- mice reconstituted with human bone marrow derived from subjects treated with PTH or ALN.
17 Recruiting Twenty Four Month Extension Study of BA058-05-003
Condition: Postmenopausal Osteoporosis
Intervention: Drug: Alendronate
Outcome Measures: Safety;   Vertebral Fracture Incidence;   Non-vertebral Fracture Incidence
18 Recruiting Bisphosphonate Biomarker Study
Conditions: Osteoporosis, With or Without Treatment;   Bisphosphonate Treatment;   Atypical Femur Fracture;   Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ);   Healthy Volunteers
Intervention:
Outcome Measures: Absorption, Distribution, Metabolism, Excretion (ADME) Profiling of DNA from all sample types vs. normative data for the ADME panel and across study groups;   Differential expression of miRNA biomarkers across participant groups within the study
19 Recruiting Effectiveness of DiscontinuinG bisphosphonatEs Study: R21 Pilot Study
Condition: Osteoporosis
Intervention: Drug: Alendronate
Outcome Measures: Clinical site recruitment rate;   Participant recruitment rate;   Contracting and procedures;   Administrative procedures;   Osteonecrosis of the jaw;   Atypical femoral fracture;   Clinical fracture rate
20 Recruiting Acute Effect of Teriparatide With Bisphosphonate or Denosumab on Bone Resorption
Condition: Postmenopausal Osteoporosis
Intervention: Drug: Teriparatide 40-mcg subcutaneous injection
Outcome Measure: Bone turnover marker (blood sample)