| Rank |
Status |
Study |
| 1 |
Not yet recruiting
|
Ranolazine for Improving Symptoms of Palpitations
| Condition: |
Ischemic Heart Disease |
| Interventions: |
Drug: Ranolazine; Drug: Placebo |
| Outcome Measures: |
Occurrence of symptoms of Palpitations; Occurrence of arrhythmia in case of symptoms of Palpitations |
|
| 2 |
Unknown †
|
Palpitations and Tachycardia in Fibromyalgia Syndrome
| Condition: |
Fibromyalgia Syndrome |
| Intervention: |
Other: Evaluation of autonomic parameters |
| Outcome Measure: |
|
|
| 3 |
Unknown †
|
Use of Loop Recorders for Diagnosis of Palpitations in A&E
| Condition: |
Palpitations |
| Intervention: |
Device: Implantable Loop Recorder |
| Outcome Measures: |
The primary endpoint of the study is the proportion of patients achieving a definite diagnosis in each of the two groups at the end of one year; The time taken from randomisation in the A&E to making the diagnosis (if any) in each group; The cost of achieving a diagnosis in each group |
|
| 4 |
Recruiting
|
Ablation of Inappropriate Sinus Tachycardia
| Condition: |
Inappropriate Sinus Tachycardia |
| Intervention: |
Procedure: electrophysiology study and radiofrequency ablation |
| Outcome Measures: |
Improvement in:symptoms(Palpitations);quality of life;resting heart rate;mean 24 hour heart rate;heart rate variability;; duration of symptom limited Bruce protocol exercise treadmill test;duration of exercise test required to increase rate by 20%. |
|
| 5 |
Unknown †
|
Influence of Nebivolol on Postmenopausal Women
| Conditions: |
Hot Flashes; Heart Rate; Blood Pressure; Endostatin; Sexual Function |
| Intervention: |
|
| Outcome Measures: |
Number of hot flashes/Palpitations; Hemodynamic changes; Sexual function; Endostatin; Quality of life |
|
| 6 |
Recruiting
|
Validation of an iPhone-based Event Recorder for Arrhythmia Detection
| Condition: |
Arrhythmia, Palpitations, Lightheadedness |
| Intervention: |
Device: Alivecor monitor and 14 day event monitor |
| Outcome Measure: |
Validation of an iPhone-based Event Recorder for Arrhythmia Detection |
|
| 7 |
Not yet recruiting
|
Sternal ECG Patch Comparison Trial
| Conditions: |
Syncope; Presyncope; Palpitations; Atrial Fibrillation; Supraventricular Tachycardia |
| Intervention: |
|
| Outcome Measures: |
ECG signal quality; Device comfort |
|
| 8 |
Not yet recruiting
|
Comparison of Continuous Sternal ECG Patch Monitors (Carnation and Zio) Trial
| Conditions: |
Syncope; Presyncope; Palpitations; Atrial Fibrillation; Supraventricular Tachycardia |
| Intervention: |
|
| Outcome Measures: |
ECG signal quality; Device comfort |
|
| 9 |
Recruiting
|
Acupuncture for Relieving Perimenopausal Symptoms
| Condition: |
Perimenopause |
| Interventions: |
Other: Acupuncture; Drug: Climen 21 Tablets |
| Outcome Measures: |
Menopause Rating Scale; Menopausal Specific Quality of Life Questionnaire; Average hot flash score during 24 hours; Level of Estradiol in serum; Level of follicle stimulating hormone in serum; Level of luteinizing hormone in serum |
|
| 10 |
Not yet recruiting
|
Study to Reduce Symptoms of Premature Beats With Ranolazine
| Condition: |
Premature Ventricular Beats |
| Intervention: |
Drug: Ranolazine |
| Outcome Measures: |
Reduction in Premature Ventricular Beats; Changes in transthoracic echocardiographic parameters; Frequency of Palpitations; Reduction of Premature Atrial Beats; Measure Temperature Rebound Rate (TRR) |
|
| 11 |
Recruiting
|
Using a Personal Heart Rhythm Monitor to Diagnose Paroxsymal Atrial Fibrillation in the Community
| Conditions: |
Paroxysmal Atrial Fibrillation; Stroke |
| Interventions: |
Device: Automated Cardiac Event Recorder; Device: Personal Heart Rhythm Monitor |
| Outcome Measures: |
The diagnostic yield of a Personal Heart Rhythm Monitor (PHRM), used for 3 months, compared to an automated cardiac event recorder (ACER), used for 1 week, to detect all episodes of paroxysmal atrial fibrillation.; The diagnostic yield of a Personal Heart Rhythm Monitor (PHRM), used for 3 months, compared to an automated cardiac event recorder (ACER), used for 1 week, to detect prolonged episodes of paroxysmal atrial fibrillation (defined as greater than 12 hours).; The sensitivity and specificity of serum biomarkers to detect cases of PAF.; The sensitivity and specificity of markers of left atrial function to predict PAF.; The development of AF in a cohort confirmed to have frequent atrial ectopic beats (APBs) over a one year period.; Adverse events (including stroke/TIA, myocardial infarction, significant bleeding events and death) at six and twelve month intervals.; Stroke reduction in the local area; Referrals to secondary care for suspected AF/Palpitations; Participant satisfaction with the devices used in the study. |
|
| 12 |
Recruiting
|
Catheter Cryoablation Versus Antiarrhythmic Drug as First-Line Therapy of Paroxysmal Atrial Fibrillation
| Condition: |
Symptomatic Paroxysmal Atrial Fibrillation Without Clinically Significant Heart Diseases |
| Interventions: |
Device: cryoballoon ablation system; Drug: Antiarrhythmic Drugs |
| Outcome Measures: |
Freedom from any atrial arrhythmia recurrence; quality of life; Hospital or emergency services accesses; Freedom from occurrence of AF; Freedom from occurrence of documented left atrial tachycardia and left atrial flutter; Symptomatic Palpitations burden; Severe adverse events incidence; Freedom from persistent AF; Echocardiographic left atrial re-modelling; health care utilization |
|
| 13 |
Unknown †
|
Registry of Unexplained Cardiac Arrest
| Conditions: |
Cardiac Arrest; Long QT Syndrome; Brugada Syndrome; Catecholamine Sensitive Polymorphic Ventricular Tachycardia; Idiopathic Ventricular Fibrillation; Early Repolarization Syndrome |
| Intervention: |
|
| Outcome Measure: |
|
|
| 14 |
Recruiting
|
Pathophysiology of Orthostatic Intolerance
| Conditions: |
Tachycardia; Postural Orthostatic Tachycardia Syndrome |
| Interventions: |
Radiation: DAXOR; Procedure: QSweat; Drug: Intrinsic Heart Rate |
| Outcome Measures: |
Physiological abnormalities in orthostatic intolerance; blood volume; intrinsic heart rate; quantitative sweat testing; residual sympathetic function after pharmacological autonomic blockade; norepinephrine spillover |
|
| 15 |
Recruiting
|
Effect of a Medium Chain Triglyceride Supplemented Diet on Cognitive Function and Brain Activation in Type 1 Diabetes.
| Conditions: |
Hypo-unawareness; Type 1 Diabetes. |
| Intervention: |
Dietary Supplement: Medium chain triglycerides |
| Outcome Measures: |
Cognitive function tests; Brain activity |
|
| 16 |
Unknown †
|
Evaluation of the Effects of L-Carnitine Injection in Patients Undergoing Hemodialysis
| Conditions: |
Cardiac Complications; Signs and Symptoms; Muscle Weakness; Anemia; Hypotension |
| Intervention: |
Drug: L-Carnitine Injection |
| Outcome Measures: |
weakness; improvement of hypotension and hematology profile; reduction of erythropoietin requirement; increase of plasma carnitine concentration; including all the components of the primary endpoints for their further assessment; improvement of the nutritional indexes; intradialytic complications (muscle symptoms, dyspnea, Palpitations); quality of life |
|
| 17 |
Recruiting
|
The Maintenance of Human Atrial Fibrillation
| Conditions: |
Atrial Fibrillation; Arrhythmias, Cardiac |
| Intervention: |
|
| Outcome Measure: |
recurrence of atrial fibrillation |
|
| 18 |
Unknown †
|
Amiodarone Compared to Dronedarone , Post Cardioversion Maintenance of Sinus Rhythm
| Condition: |
Atrial Fibrillation |
| Interventions: |
Drug: amiodarone; Drug: Dronedarone |
| Outcome Measures: |
maintenance of sinus rhythm at one year post DC Cardioversion; tolerability of amiodarone compared to dronedarone; measures of quality of life and symptoms in amiodarone compared to dronedarone |
|
| 19 |
Not yet recruiting
|
Early Elimination of Premature Ventricular Contractions in Heart Failure
| Conditions: |
Premature Ventricular Contractions; Congestive Heart Failure |
| Intervention: |
Device: PVC ablation |
| Outcome Measures: |
change of left ventricular ejection fraction measured with Simpson's rule expressed in percent from pre to post intervention; Change of echocardiographic Parameters; Change in serum biomarker level; Change in Heart Failure Symptoms |
|
| 20 |
Recruiting
|
The Leiden Nonischemic Cardiomyopathy Study
| Conditions: |
Cardiomyopathy, Dilated; Tachycardia, Ventricular; Ventricular Fibrillation |
| Interventions: |
Other: Transthoracic echocardiography; Other: Exercise test; Other: 24-hour Holter electrocardiogram; Other: Contrast-enhanced magnetic resonance imaging; Other: 123-iodine metaiodobenzylguanidine imaging; Other: Blood samples; Genetic: Genetic analysis; Procedure: Invasive electrophysiological study; Procedure: Endomyocardial biopsy; Procedure: Intraoperative biopsy; Procedure: Intraoperative mapping and/or ablation |
| Outcome Measures: |
Inducibility of ventricular arrhythmias; Type of induced ventricular arrhythmias; Spontaneous ventricular arrhythmias; Type of spontaneous ventricular arrhythmias; Hospital admissions for heart failure; Cardiac mortality; All-cause mortality; LV function/dimensions/compact fibrosis deterioration as assessed by 123-I MIBG imaging and/or CE-MRI |
|
