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PLEURAL EFFUSION and Tylenol

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PLEURAL EFFUSION Symptoms and Causes

Your pleura is a large, thin sheet of tissue that wraps around the outside of your lungs and lines the inside of your chest cavity. Between the layers of the pleura is a very thin space. Normally it's filled with a small amount of fluid. The fluid helps the two layers of the pleura glide smoothly past each other as your lungs breathe air in and out.

Disorders of the pleura include

  • Pleurisy - inflammation of the pleura that causes sharp pain with breathing
  • Pleural effusion - excess fluid in the pleural space
  • Pneumothorax - buildup of air or gas in the pleural space
  • Hemothorax - buildup of blood in the pleural space

Many different conditions can cause pleural problems. Viral infection is the most common cause of pleurisy. The most common cause of pleural effusion is congestive heart failure. Lung diseases, like COPD, tuberculosis, and acute lung injury, cause pneumothorax. Injury to the chest is the most common cause of hemothorax. Treatment focuses on removing fluid, air, or blood from the pleural space, relieving symptoms, and treating the underlying condition.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for PLEURAL EFFUSION

PLEURAL EFFUSION treatment research studies

Tylenol clinical trials, surveys and public health registries


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Tylenol Side Effects

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Transmission Of An Infectious Agent Via A Medicina (315)
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Acute Hepatic Failure (63)
Weight Decreased (63)
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Cerebrovascular Accident (45)
Blood Pressure Increased (45)
Back Pain (43)
Fall (42)
Rectal Haemorrhage (42)
Suicide Attempt (42)
Renal Failure Acute (41)
Hyperhidrosis (40)
Hypertension (39)
Abdominal Discomfort (38)
Death (38)

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Recent Reviews

Broke out in hives and itching for hours even benadryl wouldn't help

I get chronic headaches and migraines (yes, I have been advised to see a neurologist). I became ill with a headache saturday (may 14, 2011) afternoon and went to bed early hoping I could sleep it off. I kept waking up through the evening with little

Unresponsive to 5mg/kg q 8wks; increased to 10mg/kg q6wks. After 3 doses at that strength noted fatigue, occasional night sweats, joint aches, sudden onset of chest pain and dyspnea (pleurisy, small pleuraleffusion) Had just taper

54y/o, WM, Status post quadruple coronary artery bypass graft surgery(10 months ago). Surgery went well, only complication was a pretty large left pleural effusion requiring chest tube placement. Resolved well, no further problems

Experienced weakness and fatigue, diagnosed with pericardial effusion and anemia, hospitalized for 14 days. Surgical thorectomy and drainage.

Feb 2009 hospitalized for pericardal effusion then suffered with reaccuring pericarditis for a year march 2101 sent to mayo clinic in minnasota for a radical pericardectomy

Hi am a nursing student and my pt has pneumonia and pleural effusion and empyema withlarge abcessand the hostpital is giving him perfalgan is that wrong?

My father died last week after suffering from: fluid buildup in the lining of the lungs (pleural effusion), heart (pericardial effusion), led to hard breathing, fatigueandvery low oxygen in

When people receive a lung transplant, the pleural cavity is destroyed. How are people able to breathe following a lung transplant when there is no pleural cavity???

PLEURAL EFFUSION Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Analgesic Effect of Paracetamol, Paracetamol + Codeine, Ibuprofen and Their Combination
Condition: Pain, Postoperative
Interventions: Drug: Ibuprofen + Paracetamol;   Drug: Ibuprofen + Paracetamol + Codeine;   Drug: Paracetamol + Codeine;   Drug: Placebo
Outcome Measures: Sum pain intensity SPI (0-10 Numerical Rating Scale);   Sum pain intensity difference score (PID);   Overall assessment of efficacy (4-point Verbal Rating Scale);   Adverse effects AE (Specific reporting of AE - type, duration and severity)
2 Not yet recruiting Equality Study of Ofirmev vs Oral Acetaminophen
Condition: Pain, Postoperative
Interventions: Drug: IV acetaminophen;   Drug: oral acetaminophen
Outcome Measures: Primary outcome will measure total opioid consumption while the patient is in the PACU;   time from PACU admission to request for first opioid dose
3 Unknown  Acetaminophen for Cancer Pain
Conditions: Cancer;   Pain
Interventions: Drug: Acetaminophen;   Drug: acetaminophen;   Drug: placebo, sugar pill
Outcome Measures: Patient preference for the acetaminophen or the placebo arm as assessed by asking the patient whether he/she preferred treatment period 1 or treatment period 2;   Differences in the mean pain intensity score as assessed by the daily average Numeric Rating Scale (NRS) pain score during the week given acetaminophen compared with the daily average NRS pain score during the week given placebo;   Symptoms possibly associated with acetaminophen use for each period using an NRS: feeling sick (nausea and vomiting);   drowsiness;   constipation;   cold sweats;   overall sense of well being;   Total analgesic consumption in each treatment period;   Best and worst pain scores for each treatment period;   Pain relief obtained in each treatment period;   Effect of pain on functional ability;   Strength of preference for acetaminophen versus placebo on a 5-point scale;   Proportion of patients who had a preference for acetaminophen who perceived the improvement warranted taking the additional tablets;   Proportion of patients having a clinically significant improvement in pain (defined as an improvement in mean NRS of at least 33% during the week taking acetaminophen)
4 Recruiting Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery
Condition: Chronic Sinusitis
Interventions: Drug: IV Acetaminophen;   Drug: Placebo
Outcome Measures: Assess the efficacy of IV acetaminophen in controlling postoperative pain;   Investigate the effect of IV acetaminophen on the use of postoperative opioid analgesics;   Analyze effects of IV acetaminophen on intraoperative analgesic use;   Identify potential correlation between vital signs and postoperative pain intensity;   Examine the effect of IV acetaminophen on post-operative quality of recovery
5 Recruiting Paracetamol (Acetaminophen) for Closure of PDA in Preterm Infants
Condition: PDA
Interventions: Drug: Paracetamol;   Drug: Ibuprofen;   Procedure: Closure of PDA
Outcome Measures: Closure of arterial duct - yes / No;   Need for surgical closure of arterial duct
6 Recruiting Paracetamol Effect on Oxidative Stress and Renal Function in Severe Malaria
Condition: Malaria
Interventions: Drug: Paracetamol;   Drug: No Paracetamol
Outcome Measures: Effect of paracetamol concentrations;   Compare treatment arm with control arm with respect to duration of Acute Kidney Injury (AKI) and development of AKI.;   Oxidative stress assessed by measuring F2-isoprostanes (F2-IsoPs);   Assessment of Blackwater fever;   Mortality trends;   Intravascular Haemolysis;   Fever clearance time;   Parasite clearance time;   Parasite sequestration;   Assessment of Acute Kidney Injury;   Creatinine clearance;   Safety assessment
7 Recruiting Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis
Condition: Bacterial Meningitis
Interventions: Drug: Infusion with paracetamol;   Drug: Bolus without paracetamol
Outcome Measures: Mortality;   Status on the modified Glasgow Outcome Scale;   Death or any sequelae;   A change in hearing threshold compared to the first test result;   Death or severe neurological sequelae;   Deafness
8 Unknown  Paracetamol for Cancer Pain
Conditions: Advanced Cancer;   Opioid Use, Unspecified
Interventions: Drug: paracetamol;   Drug: placebo tablets
Outcome Measures: Pain reduction caused by paracetamol 4g/d;   Overall satisfaction with the pain treatment
9 Recruiting Clinical Study Comparing the Efficacy of Transbuccal Paracetamol 125 mg Versus Paracetamol Injection 1g in Slow Infusion IV in Patients With Acute Pain
Condition: Acute Pain
Interventions: Drug: paracetamol;   Drug: Placebo
Outcome Measure: Pain score measured by visual analogue scale
10 Unknown  The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children
Condition: Asthma
Intervention: Drug: paracetamol
Outcome Measure: A measurable change in lung functions in response to paracetamol exposure.
11 Recruiting Prospective, Randomized, Double Blind Study Comparing IV vs PO Acetaminophen in Patients Undergoing Lumbar Discectomy
Condition: Pain
Interventions: Drug: oral acetaminophen;   Drug: intravenous acetaminophen
Outcome Measures: Postoperative pain scores;   Quantity of intraoperative and postoperative opioids administered.
12 Recruiting Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Conditions: Emergence Agitation;   Pain
Intervention: Drug: Acetaminophen
Outcome Measures: Emergence Agitation;   Pain
13 Recruiting Analgesic Efficacy of Intravenous Acetaminophen After Video-assisted Thoracic Surgery
Condition: Video-assisted Thoracic Surgery
Interventions: Drug: IV Acetaminophen;   Drug: Saline Placebo
Outcome Measures: Total morphine consumption;   Number of PCA morphine bolus requests;   Pain Scores;   Vital signs
14 Recruiting A Prospective, Randomized, Double Blind, Comparative-effectiveness Study Comparing Perioperative Administration of Oral Versus Intravenous Acetaminophen for Laparoscopic Cholecystectomy
Condition: Laparoscopic Cholecystectomy
Interventions: Drug: 2 capsules Oral Tylenol 2000 mg and IV "salt water";   Drug: IV Tylenol 1000mg and 2 oral capsule "sugar pills"
Outcome Measures: Pain;   Opioid Use
15 Not yet recruiting Adding Paracetamol to Ibuprofen for Treatment of Patent Ductus Arteriosus in Preterm Infants
Condition: Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants
Interventions: Drug: Paracetamol;   Drug: Placebo
Outcome Measures: The incidence of patent ductus arteriosus closure;   The need for surgical ligation for PDA;   Adverse effects
16 Recruiting Intravenous Acetaminophen for Non-Narcotic Postoperative Pain Management Following Knee Arthroscopy
Condition: Pain, Postoperative
Intervention: Drug: Intravenous Acetaminophen
Outcome Measures: Postoperative pain levels;   Postoperative opioid consumption
17 Recruiting Intravenous Acetaminophen in Craniotomy
Condition: Postoperative Pain
Interventions: Drug: Acetaminophen;   Drug: Placebo
Outcome Measures: Post-Operative Opioid Requirement;   Intra-Operative Opioid Requirement;   Post-Operative Pain;   Post-Operative Side Effects
18 Recruiting Efficacy of IV Acetaminophen for Pain Management
Condition: Post-operative Pain
Interventions: Drug: Placebo (normal saline);   Drug: IV acetaminophen
Outcome Measures: Amount of opioid rescue needed;   Time to return of bowel function (passage of flatus);   Patient Satisfaction;   Cost Effectiveness
19 Recruiting Acetaminophen Versus Ibuprofen in Children With Asthma
Conditions: Asthma;   Wheezing
Interventions: Drug: Acetaminophen;   Drug: Ibuprofen
Outcome Measure: exacerbation frequency
20 Recruiting The Efficacy of Intravenous Acetaminophen During The Perioperative Period Of Neurosurgical Patients Undergoing Craniotomies
Conditions: Craniotomy;   Brain Surgery
Interventions: Drug: Acetaminophen;   Drug: Placebo
Outcome Measures: Opioid requirement after surgery;   Time to rescue medication in both groups;   Amount of rescue medication in PACU in both groups;   Median difference in ICU length of stay/hospital length of stay between both groups;   Number of successful neurologic exams between intervention and placebo group as determined by a neurosurgical provider by answering either Yes or No;   Median difference in temperature between intervention and placebo groups;   Sedation scores measured by RASS every 8 hours for 24 hours in both groups;   Pain VAS scores (1-10) every 8 hours for 24 hours in both groups;   Delirium measured by CAM-ICU every 8 hours for 24 hours in both groups