| Rank |
Status |
Study |
| 1 |
Recruiting
|
Comparison of Absorption of Vaginal Diazepam Using Different Delivery Systems
| Condition: |
Metabolism, Drug |
| Interventions: |
Drug: Diazepam tablet, 5 mg, vaginal; Drug: Diazepam Suppository, 5 mg, vaginal; Drug: Diazepam Cream, 5 mg, Vaginal |
| Outcome Measures: |
Serum Diazepam levels measured over time; Side effects observed with each of three types of vaginal Diazepam |
|
| 2 |
Recruiting
|
Vaginal Diazepam for the Treatment of Female Pelvic Pain
| Conditions: |
Pelvic Floor Disorders; Pelvic Pain |
| Interventions: |
Drug: Diazepam; Drug: Placebo |
| Outcome Measures: |
Change from baseline in Visual Analog Pain Scale score at 4 weeks, 12 weeks, and 24 weeks.; Change from baseline in Pelvic Floor Distress Inventory-20 Questionnaire score at 4 weeks, 12 weeks, and 24 weeks.; Change from baseline in McGill Pain Questionnaire score at 4 weeks, 12 weeks, and 24 weeks.; Change from baseline in Global Response Assessment score at 4 weeks, 12 weeks, and 24 weeks. |
|
| 3 |
Recruiting
|
Lofexidine for Inpatient Opiate Detox in Singapore
| Condition: |
Opiate Dependent Patients Who Are Undergoing Inpatient Detoxification in Singapore |
| Interventions: |
Drug: Lofexidine; Drug: Diazepam; Drug: Placebo for Lofexidine; Drug: Placebo for Diazepam |
| Outcome Measures: |
To evaluate differences in OOWS (Objective Opiate Withdrawal Scale); To evaluate differences in SOWS (Short Opiate Withdrawal Scale); To evaluate differences in pupil sizes; To evaluate differences in craving on the Visual Analogue Scale; To evaluate differences in time to drop-out (length of stay on the ward); To evaluate differences in emotional/psychological symptoms |
|
| 4 |
Unknown †
|
Performance Study of the SOLO 2.0 Insulin Pump
| Condition: |
Type 1 Diabetes |
| Intervention: |
Device: SOLO insulin pump |
| Outcome Measures: |
Device related safety issues; SOLO use errors; Device-related adverse outcome; Diabetes-related adverse outcome; Satisfaction iwth SOLO; Product quality (MTBF) |
|
| 5 |
Recruiting
|
Safety and Feasibility Study of Enhanced Recovery in Pancreaticoduodenectomy
| Condition: |
Pancreaticoduodenectomy (E04.210.760) |
| Interventions: |
Behavioral: Enhanced recovery after surgery protocol; Procedure: Standard perioperative care; Drug: PONV prophylaxis with Ondansetron + Dexamethasone; Other: Postoperative mobilization program; Drug: Epidural analgesia with naropin + sufentanil; Drug: Pre-anesthetic medication with Diazepam; Behavioral: Preadmission counselling; Drug: Preoperative bowel preparation with sodium phosphate |
| Outcome Measures: |
Adherence to the pathway; Postoperative outcome |
|
| 6 |
Recruiting
|
A Prospective Trial to Reduce Post-Operative Pain in Implant Based Breast Reconstruction
| Condition: |
Post-operative Pain |
| Interventions: |
Drug: Bupivacaine; Drug: Botulinum Toxins; Drug: Analgesics |
| Outcome Measure: |
Pain Score Questionnaire |
|
| 7 |
Recruiting
|
Perioperative Δ9-THC for Postsurgical Pain
| Condition: |
Pain |
| Interventions: |
Drug: Namisol; Drug: Diazepam/placebo |
| Outcome Measures: |
Analgesic efficacy; Incidence of persistent continuous or intermittent postsurgical abdominal pain |
|
| 8 |
Unknown †
|
The Effect of Prescription Medications in Marijuana Users
| Condition: |
Marijuana Abuse |
| Intervention: |
Drug: bupropion, Diazepam, dronabinol, ramelteon (Investigational Drug) |
| Outcome Measures: |
marijuana withdrawal; subjective effects of smoked marijuana; cognitive performance |
|
| 9 |
Recruiting
|
The PROOF Study: The PICC Related Obstruction Of Flow Study
| Condition: |
Patients Indicated for a PICC for Any Medical Condition |
| Interventions: |
Device: BioFlo™ Peripherally Inserted Central Catheter (PICC); Device: Bard® Dual-Lumen PowerPICC SOLO2® |
| Outcome Measures: |
Incidence of catheter-related venous thrombosis as confirmed by diagnostic ultrasound; Incidence of other catheter-related complications |
|
| 10 |
Not yet recruiting
|
Implementing Health Plan-Level Care Management for Solo & Small Practices
| Conditions: |
Bipolar Disorder; Depression |
| Interventions: |
Behavioral: Chronic Care Model for Mood Disorders; Other: Educational Control |
| Outcome Measures: |
Quality of Life; Reduced Mood Disorder Symptoms; Improved Guideline-Concordant Care; Reduced Hospitalizations; Improved Work Productivity |
|
| 11 |
Unknown †
|
Positron Emission Mammography (PEM) Flex Solo II Positron Emission Tomography (PET) Scanner and Stereo Navigator Biopsy Accessory for the Diagnosis of Breast Cancer
| Condition: |
Breast Cancer |
| Intervention: |
Procedure: PEM Breast Biopsy |
| Outcome Measures: |
Evidence that breast biopsy can be performed using PEM and Stereo Navigator software; Evidence that breast biopsy can be performed in less clinical visits than if biopsy is performed using MRI, mammogram, and/or ultrasound |
|
| 12 |
Unknown †
|
Quality of Sleep in Patients With Rheumatoid Arthritis
| Condition: |
Rheumatoid Arthritis |
| Intervention: |
Drug: Diazepam, melatonin |
| Outcome Measure: |
|
|
| 13 |
Recruiting
|
Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental Disability
| Condition: |
Dental Care for Disabled |
| Interventions: |
Drug: Midazolam Mylan; Drug: Lorazepam Mylan; Drug: Valium + Akineton + Dehydrobenzperidol + Atropine sulfate |
| Outcome Measures: |
Level of cooperation of patient when receiving regular dental care; Recording of vital parameters during regular dental care delivery; Level of patient comfort and possible side-effects after dental treatment session |
|
| 14 |
Recruiting
|
Tolerance of PICC Line Versus Implanted Port for Adjuvant Chemotherapy in Early Breast Cancer
| Condition: |
Early Stage Breast Carcinoma |
| Interventions: |
Device: implanted port for chemo administration (X-port isp); Device: Use of a PICC line for chemo administration (PowerPICC SOLO²) |
| Outcome Measures: |
Probability of occurrence of a significant adverse event related to the central venous device; Patients' satisfaction for the use of their central venous device |
|
| 15 |
Unknown †
|
Continuation Electroconvulsive Therapy (C-ECT) for Relapse Prevention in Major Depression
| Condition: |
Depression |
| Interventions: |
Device: Thrymatron System IV device (CONSOLIDATION ELECTROCONVUsLIVE THERAPY) plus PHARMACOTHERAPY; Drug: PHARMACOTHERAPY |
| Outcome Measures: |
Hamilton Depression Rating Scale 21 items (HDRS-21); Mini-Mental State Examination (MMSE 35); UKU - Adverse effects rating scales; Demographical Data Memory (MEDABI-20); Rey Figure; Trail Making Test A; Trail Making Test B; Stroop Test; Direct and inverse digits (WAIS, Weschler Adults Intelligence Sacle).; Vocabulary WAIS (Weschler Adults Intelligence Scale); Frequency Hospitalization Quotient; Hospital Day Quotient (HDQ) |
|
| 16 |
Recruiting
|
RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
| Condition: |
Respiratory Insufficiency |
| Interventions: |
Device: Vibrating Mesh Nebulizer Arm; Device: Jet Nebulizer Arm |
| Outcome Measures: |
Venilator Associated Events; Bacterial Count and type; Length of Stay in Intensive Care Unit; Days on Mechanical Ventilation; Ventilator-Associated Tracheobronchitis |
|
| 17 |
Recruiting
|
Gabapentin Treatment of Benzodiazepine Dependence
| Condition: |
Benzodiazepine Dependence |
| Interventions: |
Drug: gabapentin; Drug: Placebo |
| Outcome Measure: |
Abstinence from Benzodiazepine use |
|
| 18 |
Recruiting
|
Electrical Status Epilepticus in Sleep: Response of Neuropsychological Deficits and Epileptiform Activity to Clobazam Treatment
| Condition: |
Electrical Status Epilepticus in Sleep |
| Intervention: |
Drug: ESES treated with clobazam |
| Outcome Measures: |
Cognitive ability; Language; Executive function; Adaptive/development skills; Behavior; Interictal epileptiform activity |
|
| 19 |
Recruiting
|
Carbon Dioxide (Carbogen) for the Treatment of Febrile Seizures
| Condition: |
Febrile Seizure |
| Interventions: |
Drug: Carbogen; Drug: Placebo |
| Outcome Measures: |
number of patients which need Diazepam; number of severe adverse events; manageability of the application assessed by the parents; changes in quality of life of the parents and children after use of study medication; contentment and anxiety of the parents |
|
| 20 |
Unknown †
|
Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
| Condition: |
Spastic Cerebral Palsy |
| Interventions: |
Drug: Extended-release Epidural morphine (EREM) 80; Drug: Extended-release Epidural Morphine (EREM) 120; Drug: Control: Saline |
| Outcome Measures: |
Quantity of fentanyl administered; Adequacy of analgesia as judged by age-adjusted pain scales.; Incidence of respiratory depression; Hemodynamic instability; Rate of CSF leak; Rate of infection; Urinary retention; Nausea and/or vomiting; Pruritis |
|
