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PRODUCT USE ISSUE and Nexium

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PRODUCT USE ISSUE Symptoms and Causes

The products you use for cleaning, carpentry, auto repair, gardening, and many other household uses can contain ingredients that can harm you, your family, and the environment. These include

  • Oven and drain cleaners
  • Laundry powder
  • Floor polish
  • Paint thinners, strippers and removers
  • Pesticides
  • Grease and rust removers
  • Motor oil and fuel additives
  • Arts and craft supplies

Toxic substances in these products can cause harm if inhaled, swallowed, or absorbed through the skin. People respond to toxic substances in different ways. At high doses a toxic substance might cause birth defects or other serious problems, including brain damage or death.

To avoid problems, keep products in the containers they come in and use them exactly as the label says. Follow label directions or get medical help if you swallow, inhale or get them on your skin.

Environmental Protection Agency

Check out the latest treatments for PRODUCT USE ISSUE

PRODUCT USE ISSUE treatment research studies

Nexium clinical trials, surveys and public health registries


Find Drug Side Effect reports



Nexium Side Effects

Gastrooesophageal Reflux Disease (3970)
Malaise (2729)
Dyspepsia (2294)
Pain (1309)
Vomiting (1209)
Osteoporosis (1201)
Abdominal Pain Upper (1180)
Abdominal Discomfort (946)
Off Label Use (840)
Fall (820)
Gastric Disorder (817)
Chest Pain (787)
Nausea (778)
Diarrhoea (704)
Aphagia (702)
Diabetes Mellitus (634)
Cerebrovascular Accident (610)
Headache (579)
Adverse Event (578)
Dyspnoea (575)
Arthritis (563)
Multiple Fractures (556)
Myocardial Infarction (551)
Hypertension (515)
Dysphagia (504)
Feeling Abnormal (495)
Insomnia (477)
Neoplasm Malignant (466)
Weight Decreased (456)
Throat Irritation (451)
Nasopharyngitis (441)
Hiatus Hernia (439)
Cough (436)
Pneumonia (430)
Bone Disorder (402)
Dizziness (378)
Back Pain (374)
Cardiac Disorder (360)
Depression (353)
Abdominal Pain (338)
Anxiety (334)
Regurgitation (327)
Road Traffic Accident (324)
Ulcer (313)
Pain In Extremity (309)
Fatigue (302)
Abdominal Distension (297)
Dysphonia (289)
Oropharyngeal Pain (286)
Chronic Obstructive Pulmonary Disease (280)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

Both feet and legs swelled up after third day of 40 mg caps

Does anyone have abdominal pain from long term Nexium use?

Extreme abdominal pain Ocassional headache Lots of air in upper and lower abdominal

Extreme dryness in then mouth and throat requiring ambulance once

Foul metallic taste in mouth,itchy skin,thrush :(

Has anyone experienced a reuction in the immune system to picking up cold and flue viruses. Since taking Nexium I am constantly catching every Every type of cold, sore throat or chest infection going around.

Hi! Some years ago I took nexium for v. severe gerd, with haemorrhage. From the time I started it, suddenly my gastric system was totally upset, where it hadn't previously. Because I wasn't digesting properly, my immune system was affected, and hav

High gloucose level?

I am fairly new to this i have been on inexium for 2 months because i was told i had barret barrett's oesophagus. pre cancer my stomach is burning all the time.i am now not wanting to take the tablets .what will happen if i stop.my doctor said the ca

I am taking mexium 20 mg regularly for last 1.5 years. Recent blood test have shown high level of liver enzymes . I am a non drinker and have never had any jaundice or any immunisation of hepatitis. Nexium definately messed up my healthy liver

i never had an issue with using theraflu before. this time around i feel drunk every time i take it. i feel really super drowsy. and it is not working at all. i am still very congested even though i have a runny nose. i am still sore all over even t

>:o Took my first dose today,it left me covered in a red itchy rash on neck,chest,back and sides within 10 minutes of consuming.This product is now sitting in the trash can. :(

Hey Michelle, we almost have the same issue..I switched from Yaz to Trinessa because I and my husband thought it caused my severe mood swings prior to my period. I have been running and working out but I start experiencing joint

<span style='color: #808080;'><b>Describe Your Nystagmus from DTAP + IPV + HIB (PENTACEL) 2010 Experience Here: My duagters very first set of vaccination shots at 3 months caused nystagmus. We did not notice the issue

'OCAS' means that the product is administered over a time period. For this reason it must be swallowed whole and not chewed.

....however, dalacine is very effective unto face. kaya ngaun patuloy na ang paggamit ko sa product na ito.. try niyo rin para masubukan niyo. sabi nga hindi mo malalaman ang tamis hangat hindi mo nasusubukan ang pa.it....jejejeje' &nb

1.2-methyl-2-butene is treated with the following reagents write the structural formula of the mian organic product in each case

According to unspsc classification ,in which commodity this product fall?

After i use sensordyne , i have extremely pain travel from the back of my throat and uperjaw to my head . I though this product will reduce sensitivity in my teeth , now i have more pain then before.

After one day, extreme fatigue and swelling in the ankles. This drug is poison and should be pulled. No warranty or return on product by manufacturer.

PRODUCT USE ISSUE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  A Double Blind Study Comparing Two Doses of IV Esomeprazole After Successful Endoscopic Therapy
Condition: Upper Gastrointestinal Bleeding
Interventions: Drug: Esomeprazole;   Drug: esomeprazole
Outcome Measure: Two different doses intravenous proton pump inhibitors in patients with peptic ulcer bleeding after successful endoscopic therapy- a prospective randomized comparative trial.
2 Unknown  Effect of Esomeprazole 40 mg.Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients With GERD
Condition: Gastroesophageal Reflux Disease
Interventions: Drug: Esomeprazole;   Drug: esomeprazole
Outcome Measure: The Effect of Esomeprazole 40 mg. Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients w/ GERD.
3 Unknown  Comparison of Nexium VS. Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE.
Conditions: Gastroesophageal Reflux Disease (GERD);   Heartburn;   Indigestion
Interventions: Drug: Secretol;   Drug: Nexium
Outcome Measure: Primary objective is to evaluate the relationship between healing and study drug allotment.
4 Recruiting The Efficacy of Double Doses of Oral Esomeprazole in Preventing Rebleeding and the Selection Criteria for Second-look Endoscopy for Patients With Bleeding Peptic Ulcers
Condition: Peptic Ulcer Bleeding
Intervention: Drug: esomeprazole (Nexium®, AstraZeneca AB, Södertälje, Sweden)
Outcome Measures: recurrent bleeding;   the length of hospitalization;   the amount of blood transfusion;   major events such as surgery or transarterial embolization;   the fading rate of major stigmata of recent hemorrhage;   mortality
5 Unknown  Study Comparing Esomeprazole Associated With Sodium Bicarbonate From Eurofarma and Esomeprazole in Treatment of Gastroesophageal Reflux Disease ESOBIC
Condition: Gastroesophageal Reflux Disease
Interventions: Drug: Nexium®;   Drug: Esomeprazol (40mg) + Sdium Bicarbonate (721mg)
Outcome Measure: Efficacy
6 Not yet recruiting Rebamipide in Combination With Esomeprazole in the Management of Asian Patients With Functional Dyspepsia
Condition: Dyspepsia
Interventions: Drug: Rebamipide;   Drug: Placebo (for Esomeprazole);   Drug: Esomeprazole
Outcome Measures: Dyspepsia symptoms;   quality of life
7 Recruiting High Dose Esomeprazole Na for Prevention of Rebleeding After Successful Endoscopic Therapy of a Bleeding Peptic Ulcer
Condition: Bleeding Peptic Ulcer
Interventions: Drug: Esomeprazole Na;   Drug: Cimetidine;   Drug: Esomeprazole Mg
Outcome Measures: The rate of clinically significant rebleeding of continuous i.v. infusion;   The rate of clinically significant rebleeding;   The rate of patients had endoscopic re-treatment due to rebleeding;   The rate of patients who had surgery due to rebleeding;   The number of blood units transfused;   The number of patients with AE during the continuous I.v. infusion;   The number of patients with AE of open oral treatment with esomeprazole Mg 40 mg;   Mean values of S-creatinine, S-ALP, S-AST, S-ALT, B-Bil, Hb, WBCand B-platelets
8 Not yet recruiting Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients
Condition: Stress Ulcer Prophylaxis
Interventions: Drug: Esomeprazole;   Drug: Cimetidine
Outcome Measures: The effectiveness of esomeprazole versus cimetidine for the prevention of upper GI bleedings;   The proportion of patients with any overt upper GI bleeding
9 Unknown  Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia
Conditions: Aspirin;   Dyspepsia
Interventions: Drug: esomeprazole;   Drug: Famotidine
Outcome Measures: Treatment success : The HKDI is less than 16. Treatment was considered to have failed if a patient had taken medication for dyspepsia (other than antacids) during the study period;   Treatment success: no significant dyspepsia defined by the Global Dyspepsia Score
10 Recruiting Comparison of the Gastric Acid Suppressive Effects of Esomeprazole and Generic Omeprazole
Condition: Gastric Acid
Interventions: Drug: Esomeprazole first;   Drug: Generic omeprazole first
Outcome Measures: Median intragastric pH and percentage of time that intragastric pH is above 4;   Nocturnal acid breakthrough, defined as at least 60 continuous minutes of intragastric pH below 4 occurring between 10pm and 6 am and adverse events
11 Recruiting Nexium Capsules LDA Specific Clinical Experience Investigation
Conditions: Gastric Ulcer;   Duodenal Ulcer
Intervention:
Outcome Measures: Adverse events incidence;   Non-recurrence rate of peptic ulcer
12 Recruiting Rate of Complete Symptom Relief, Prevention of Symptom Relapse and Maintenance: Grades A and B Esophagitis of Esomeprazole Therapy
Condition: Erosive Esophagitis
Intervention: Drug: Esomeprazole 40 mg
Outcome Measures: The Rates of Complete Symptom Relief;   The Rate of Symptom Relapse
13 Not yet recruiting A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of RO5424802 in Healthy Volunteers.
Condition: Healthy Volunteer
Interventions: Drug: RO5424802;   Other: Hight fat and calorie meal;   Other: Standard meal;   Drug: esomeprazole
Outcome Measures: Plasma area under the concentration-time curve (AUC) of RO5424802;   Incidence of adverse events;   Plasma AUC of major metabolite after RO5424802 administration
14 Unknown  The Effect of Nexium on Transmucosal Esophageal Leak
Conditions: Reflux;   Esophagitis;   Barrett's Esophagus
Intervention: Drug: Esomeprazole (Nexium) 40 mg/day
Outcome Measures: Urine sucrose level falls below 90 mg after 8 weeks of therapy;   Reduction of patient symptoms consistent with GERD
15 Unknown  Evaluation of Esomeprazole in Treating Gastro-Esophageal Reflux Disease (GERD) in Head and Neck Cancer Patients Exposed to Radiation Therapy
Condition: Gastro-Esophageal Reflux
Intervention: Drug: Esomeprazole (Nexium)
Outcome Measure:
16 Unknown  Esomeprazole, Moxifloxacin and Amoxicilin for Rescue Therapy of Helicobacter Pylori Infection
Conditions: Helicobacter Pylori Infection;   Chronic Gastritis
Interventions: Drug: esomeprazole;   Drug: moxifloxacin;   Drug: amoxicillin
Outcome Measures: Efficacy of a combination of esomeprazole (E), moxifloxacin (M) and amoxicillin (A) for third line therapy of H. pylori infection.;   Comparison of EMA 7 days versus EMA 14 days. Hypothesis: superiority of EMA 14 days 4 weeks after end of eradication therapy;   Tolerability,safety, post treatment resistance, influence of host genetics (CYP status) and pathogenicity factors of H. pylori on treatment success.
17 Unknown  Esomeprazole Treatment for Patients With Lymphocytic Gastritis
Condition: Lymphocytic Gastritis
Intervention: Drug: Esomeprazole
Outcome Measures: The primary objective is to assess the healing rate of;   patients with lymphocytic gastritis irrespective of H. pylori status after treatment;   with esomeprazole 20 mg twice daily for 2 weeks.;   Secondary objective of the study are to evaluate the grade and activity of gastritis before and after;   treatment according to updated Sydney classification, to assess the clinical GI symptoms at baseline and after 3 months;   and to evaluate influence of the H. pylori-Status
18 Recruiting A Safety Study of VIMOVO in Adolescents With Juvenile Idiopathic Arthritis (JIA)
Condition: Juvenile Idiopathic Arthritis (JIA)
Interventions: Drug: VIMOVO 250/20;   Drug: VIMOVO 375/20;   Drug: VIMOVO 500/20
Outcome Measures: Incidence of severity of AEs and SAEs.;   Change in serum iron/total iron binding capacity (serum iron/TIBC), Vitamin B12, and magnesium.;   Change from baseline in vital signs, physical examination results and clinical laboratory tests.;   Pharmacokinetic (PK) in terms of characteristics of VIMOVO (naproxen / esomeprazole).
19 Recruiting Safety, Tolerability and PK of Concomitant Esomeprazole and Rifampin, and QT Study on Single and Multiple-doses of Alisertib
Conditions: Solid Tumors;   Lymphoma
Interventions: Drug: alisertib;   Drug: esomeprazole;   Drug: rifampin
Outcome Measures: alisertib PK parameters (AUC and Cmax) in the presence (Cycle 2 Day 8) versus absence (Cycle 1 Day 1) of esomeprazole;   alisertib PK parameters (AUC and Cmax) in the presence (Cycle 2 Day 8) versus absence (Cycle 1 Day 1) of rifampin;   Change in QTc following single and multiple dose administration of alisertib;   alisertib steady-state PK parameters (AUC and Cmax);   Number of adverse events;   Changes in ECG intervals following single and multiple dose administration of alisertib
20 Unknown  Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese Patients
Condition: Gastroesophageal Reflux Disease
Interventions: Drug: 10 mg ilaprazole;   Drug: 15 mg ilaprazole;   Drug: 40 mg esomeprazole
Outcome Measures: the proportion of patients with healed esophagitis at week 8;   the proportion of patients healed at week 4;   resolution of clinical symptoms