PYREXIA and Penicillin

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PYREXIA Symptoms and Causes

A fever is a body temperature that is higher than normal. A normal temperature can vary from person to person, but it is usually around 98.6 F. A fever is not a disease. It is usually a sign that your body is trying to fight an illness or infection.

Infections cause most fevers. You get a fever because your body is trying to kill the virus or bacteria that caused the infection. Most of those bacteria and viruses do well when your body is at your normal temperature. But if you have a fever, it is harder for them to survive. Fever also activates your body's immune system.

Other causes of fevers include

Medicines, including some antibiotics, blood pressure medicines, and anti-seizure medicines
Heat illness
Cancers
Autoimmune diseases
Some childhood immunizations

Treatment depends on the cause of your fever. If the fever is very high, your health care provider may recommend taking an over-the-counter medicine such as acetaminophen or ibuprofen. Adults can also take aspirin, but children with fevers should not take aspirin. It is also important to drink enough liquids, to prevent dehydration.

Check out the latest treatments for PYREXIA

➢ PYREXIA treatment research studies

➢ Penicillin clinical trials, surveys and public health registries

Find Drug Side Effect reports

Penicillin Side Effects

Rash (32)

Pain (26)

Hypersensitivity (23)

Pruritus (17)

Urticaria (16)

Toxic Epidermal Necrolysis (14)

Dyspnoea (14)

Oedema Peripheral (13)

Pyrexia (13)

Vomiting (13)

Chest Pain (12)

Deep Vein Thrombosis (12)

Anxiety (12)

Erythema (11)

Headache (11)

Nausea (11)

Diarrhoea (9)

Injury (9)

Emotional Distress (9)

Swelling Face (8)

Pulmonary Embolism (8)

Alanine Aminotransferase Increased (8)

Pain In Extremity (7)

Renal Failure Acute (7)

Malaise (7)

Abdominal Pain (7)

Stevens-johnson Syndrome (7)

Rash Maculo-papular (6)

Anaphylactic Reaction (6)

Skin Exfoliation (6)

Aspartate Aminotransferase Increased (6)

Swelling (6)

Dysphagia (6)

Weight Decreased (6)

Angioedema (5)

Abdominal Pain Upper (5)

Fear (5)

Blood Creatinine Increased (5)

Haemorrhage (5)

Throat Tightness (5)

Dizziness (5)

Chromaturia (5)

Rash Pruritic (5)

Restlessness (5)

Fatigue (5)

Decreased Appetite (5)

No Adverse Event (4)

Neutropenia (4)

Blood Alkaline Phosphatase Increased (4)

Nasopharyngitis (4)

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Common Meds

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Amoxicillin (4387)

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Recent Reviews

After i took penicilin..my body all swolen

Bakpo kawe isap rokok sero xsedap ni..

CHEST PAIN WITH CHILLS

Diarrhea,

Does it affect your sexual drive?

Head ache, feeling like i am getting the flu, very tired, achey

Headache

I am weak and tired, head ekes, fewer.

I had penicillin for 3 days both in hospital by needle in my arm and orally once discharged from hospital. I was admitted for severe tonsillitus and found to have no real noticable side effects until the 2nd night where I was constantly tired yet was

I have been taking penycillin now for a week because of an infection leading to root canal. From the penycillin, I have experienced headaches, dizziness, vertigo type symptoms, body and muscle aches and cramping. Symptoms have increased as the days h

PYREXIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.

Rank

Status

Study

Recruiting

Turnover of Antigen Specific Lymphocytes After Immunization With the Yellow Fever Vaccine

Condition:	Yellow Fever
Interventions:	Biological: Yellow fever vaccine; Biological: Yellow fever vaccine and D20 water
Outcome Measures:	To evaluate the life span and decay curve of effector CD8 T cells after immunization with 17D yellow fever vaccine; To evaluate the rate of homeostatic turnover of memory CD8 T cells after immunization with 17D yellow fever vaccine

Not yet recruiting

Safety and Immunogenicity of Q Fever Vaccine

Condition:	Q Fever
Intervention:	Biological: Q fever Vaccine
Outcome Measures:	Change in Immunogenicity; Percentage of subjects with symptoms following Q fever vaccination; Percentage of subjects with erythema following Q fever vaccination along with severity and association with vaccination; Percentage of subjects with induration following Q fever vaccination along with severity and association with vaccination; Percentage of subjects with each AE, system organ class of AE, severity, and association with vaccination; Percentage of subjects with symptoms following Q fever skin test antigen; Percentage of subjects with erythema following Q fever skin test antigen along with severity and association with skin test antigen; Percentage of subjects with induration following Q fever skin test antigen along with severity and association with skin test antigen; Percentage of subjects with each AE, system organ class of AE, severity, and association with skin test antigen

Recruiting

Respiratory Physiology in Children With Febrile Seizures.

Conditions:	Febrile Illness in Children; Seizures, Febrile
Intervention:
Outcome Measures:	Change of transcutaneous pCO2 per change of body temperature [mmHg/degree C]; Change of respiratory rate per change of body temperature [1/sec * degree C]; Change of transcutaneous pCO2 per change of respiratory rate [mmHg * sec]

Recruiting

Etiologies of Fever Among Adults in Dar es Salaam

Condition:	Acute Febrile Illnesses
Intervention:
Outcome Measures:	Proportion of patients with each disease among all febrile patients, overall and stratified by HIV status; Proportion of febrile patients with acute respiratory infection infected with a certain respiratory pathogen, compared to the proportion of healthy controls infected with the same pathogen.

Recruiting

Hyperthermia and Proton Therapy in Unresectable Soft Tissue Sarcoma

Condition:	Soft Tissue Sarcoma
Intervention:	Radiation: Hyperthermia and Proton Beam
Outcome Measures:	To evaluate safety of hyperthermia and proton beam treatment in unresectable soft tissue sarcomas; To evaluate the local response to hyperthermia and proton beam therapy as a preoperative regimen for unresectable soft tissue sarcomaLocal control

Not yet recruiting

Short Versus Extended Antibiotic Treatment With a Carbapenem for High-risk Febrile Neutropenia in Hematology Patients With FUO

Conditions:	Febrile Neutropenia; Hematological Malignancy
Intervention:	Drug: Discontinuation of imipenem-cilastatin or meropenem
Outcome Measures:	The percentage of patients with failed treatment; All-cause mortality; Infection-related mortality; The length of hospitalization in days; Unexpected re-admission other than for planned chemotherapy or other elective treatment.; The recurrence of fever within 24 hours after discontinuation of antibiotic therapy.; The total number of febrile episodes during neutropenia; Time to defervescence; Antibiotic or antifungal treatment within 30days after discharge other than standard antibiotic prophylaxis.; Incidence and prevalence of Clostridium difficile infection; Incidence and prevalence of liver and kidney dysfunction; Candida spp. colonization in (surveillance) cultures; Cost of antimicrobial therapy per admission; MASCC-score; The percentage of patients with mucositis and positive blood cultures or short treatment failure.; Bacterial resistance in blood cultures and surveillance cultures (including minimal inhibitory concentrations (MIC)).

Recruiting

Human Immune Responses to The Yellow Fever Virus Vaccine

Condition:	Yellow Fever
Intervention:	Biological: Yellow fever vaccine
Outcome Measures:	1. Isolation and characterization of yellow fever vaccine (YFV-17D) specific adaptive immune responses: characterize the magnitude and quality of YFV specific T cell responses, antibody secreting cells and memory B cells.; Determine the signatures of innate immune responses: cytokines, chemokines, dendritic cells and microarray analyses on peripheral blood mononuclear cells

Unknown ^†

A Screening Strategy for Q Fever Among Pregnant Women

Condition:	Q Fever
Intervention:	Other: screening
Outcome Measures:	obstetric or maternal complications in Q fever positive women; course of infection in pregnant women; the accuracy of the diagnostic tests used for screening; placentitis; costs

Recruiting

Pilot Study of a Catheter-based Ultrasound Hyperthermia System

Conditions:	Cervical Cancer; Prostate Cancer
Interventions:	Procedure: Hyperthermia; Radiation: HDR brachytherapy
Outcome Measures:	Evaluate the safety and tolerability of interstitial and endocavitary ultrasound hyperthermia therapy; Evaluate the feasibility, defined as being able to administer hyperthermia at a specified temperature range and thermal dose.; Characterize the interstitial and endocavitary ultrasound heating technology by describing the thermal parameters including attainable temperature and thermal dose distribution and duration at the tumor treatment region.

Unknown ^†

West Indies-French Guiana Dengue Study

Conditions:	Fever; Dengue
Interventions:	Other: biological sample collection; Other: quality of life questionnaire EuroQol®
Outcome Measures:	Occurrence, during follow-up (for 12 weeks following symptom onset), of shock, internal bleeding, failure of one or several organs or systems (brain, heart, lung, liver, kidney, clotting system), or death.; Onset of dengue hemorrhagic fever (WHO criteria). Changes in quality of life, measured with the EuroQol® questionnaire 3 and 12 weeks after the onset of dengue fever symptoms.

Recruiting

Rapid Diagnostic Tests and Clinical/Laboratory Predictors of Tropical Diseases In Patients With Persistent Fever in Cambodia, Nepal, Democratic Republic of the Congo and Sudan (NIDIAG-Fever)

Conditions:	Visceral Leishmaniasis; Human African Trypanosomiasis; Enteric Fever; Melioidosis; Brucellosis; Leptospirosis; Relapsing Fever; Rickettsial Diseases; HIV; Tuberculosis; Malaria; Amoebic Liver Abscess
Interventions:	Device: rk28 ICT; Device: IT LEISH (rK39); Device: Immunochromatographic HAT test; Device: HAT Serostrip; Device: Card Agglutination Trypanosoma Test (CATT)-10; Device: Typhidot M; Device: S. typhi IgM/IgG; Device: Test-it Typhoid IgM; Device: Test-it Leptospirosis IgM; Device: Leptospira IgG/IgM
Outcome Measures:	Prevalence of Visceral Leishmaniasis (VL), Human African Trypanosomiasis (HAT) and other Neglected Tropical Diseases (NTDs); Identification of clinical and laboratory diagnostic indicators; Identification of reliable Rapid Diagnostic Tests (RDTs); Predictive values of RDTs; Cost-effectiveness of the diagnostic tests

Recruiting

Gatifloxacin Versus Ceftriaxone in the Treatment of Enteric Fever

Conditions:	Enteric Fever; Typhoid Fever
Interventions:	Drug: Ceftriaxone; Drug: Gatifloxacin
Outcome Measures:	Rate of treatment failure; Time to fever clearance; S.typhi or S.paratyphi carriage; Number of adverse events; Household transmission

Recruiting

Aggressive Fever Control With Intravenous Ibuprofen After Non-traumatic Brain Hemorrhage

Condition:	Fever
Interventions:	Drug: Intravenous Ibuprofen; Drug: Acetaminophen (Standard of Care)
Outcome Measures:	Fever Burden; Inflammatory Markers; Cost analysis; Bleeding Incidence

Recruiting

Reliability of Subjective Assessment of Fever by Parents and Health Care Providers in Children and Adolescents

Condition:	FEVER
Intervention:
Outcome Measure:	subjective assessment of fever by both parents and medical personnel will be unreliable

Recruiting

A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles for Terminal Ovarian Cancer

Condition:	Ovarian Cancer
Intervention:	Device: ThermalCore Hyperthermia System
Outcome Measures:	Organ toxicity; Time To Progression of Disease

Recruiting

Phase 1/2 Study of ThermoDox With Approved Hyperthermia in Treatment of Breast Cancer Recurrence at the Chest Wall

Condition:	Breast Cancer
Intervention:	Drug: ThermoDox in combination with Microwave Hyperthermia (heat)
Outcome Measures:	To determine the bioequivalence of ThermoDox when used with hyperthermia among patients with RCW breast cancer.; To determine efficacy of ThermoDox in combination with Hyperthermia; To evaluate the safety of ThermoDox in combination with Hyperthermia

Recruiting

Neoadjuvant Chemoradiation With 5-FU(or Capecitabine) and Oxaliplatin Combined With Hyperthermia in Rectal Cancer

Condition:	Rectal Cancer
Interventions:	Radiation: Radiotherapy; Procedure: Hyperthermia; Drug: 5-Fluorouracil; Drug: Capecitabine; Drug: Oxaliplatin
Outcome Measures:	Feasibility rate (i.e. rate of patients not experiencing dose-limiting toxicity [DLT]); Number of hyperthermia applications by patient; Local progression-free survival; Distant metastasis-free survival; Overall survival; Response rate; Rate of R0-resections; Rate of acute and late toxicity

Unknown ^†

Cisplatin, Metronomic Low-Dose Interferon Alfa, Gemcitabine, and Fever-Range Whole-Body Hyperthermia in Treating Patients With Inoperable or Metastatic Pancreatic Cancer

Condition:	Pancreatic Cancer
Interventions:	Biological: recombinant interferon alfa; Drug: cisplatin; Drug: gemcitabine hydrochloride; Procedure: hyperthermia treatment
Outcome Measures:	Tumor response; Toxicity; Survival; Changes in quality of life; Conversion of inoperable tumors to operable; Changes in cellular and cytokine immune function

Recruiting

Effectiveness of the Combined Whole Liver Irradiation (WLI) and Hyperthermia for Gastrointestinal Tract Cancer Liver Metastasis

Condition:	The Patients With Unresectable Chemoresistant Multiple Liver Metastasis From Colorectal Cancer
Intervention:	Radiation: Combined hyperthermia and radiation therapy
Outcome Measures:	Time to local tumor progression after combined hyperthermia and RT; Objective response rate of combined hyperthermia and RT; Change from baseline quality of life at 3 months; Local tumor progression free survival rate after combined hyperthermia and RT; Adverse event after combined hyperthermia and RT.; Overall survival rate after combined hyperthermia and RT

Unknown ^†

Oral Versus Rectal Ibuprofen for Fever in Young Children - a Randomized Control Study.

Condition:	Fever
Interventions:	Drug: Ibuprofen suppository; Drug: Ibuprofen Suspension
Outcome Measures:	Maximal change in temperature during the 4-hour period after enrollment.; Proportion of patients with a drop of at least 1°C and 2°C in mean temperature at 4h. Decrement in fever at each time point, and the area under the temperature (versus time) curve. Proportion of patients with temperature < 38 at 4 hours.