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RESPIRATORY FAILURE and Thyroid

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RESPIRATORY FAILURE Symptoms and Causes

What is respiratory failure?

Respiratory failure is a condition in which your blood doesn't have enough oxygen or has too much carbon dioxide. Sometimes you can have both problems.

When you breathe, your lungs take in oxygen. The oxygen passes into your blood, which carries it to your organs. Your organs, such as your heart and brain, need this oxygen-rich blood to work well.

Another part of breathing is removing the carbon dioxide from the blood and breathing it out. Having too much carbon dioxide in your blood can harm your organs.

What causes respiratory failure?

Conditions that affect your breathing can cause respiratory failure. These conditions may affect the muscles, nerves, bones, or tissues that support breathing. Or they may affect the lungs directly. These conditions include

  • Lung diseases such as COPD (chronic obstructive pulmonary disease), cystic fibrosis, pneumonia, and pulmonary embolism
  • Conditions that affect the nerves and muscles that control breathing, such as amyotrophic lateral sclerosis (ALS), muscular dystrophy, spinal cord injuries, and stroke
  • Problems with the spine, such as scoliosis (a curve in the spine). They can affect the bones and muscles used for breathing.
  • Damage to the tissues and ribs around the lungs. An injury to the chest can cause this damage.
  • Drug or alcohol overdose
  • Inhalation injuries, such as from inhaling smoke (from fires) or harmful fumes
What are the symptoms of respiratory failure?

The symptoms of respiratory failure depend on the cause and the levels of oxygen and carbon dioxide in your blood.

A low oxygen level in the blood can cause shortness of breath and air hunger (the feeling that you can't breathe in enough air). Your skin, lips, and fingernails may also have a bluish color. A high carbon dioxide level can cause rapid breathing and confusion.

Some people who have respiratory failure may become very sleepy or lose consciousness. They also may have arrhythmia (irregular heartbeat). You may have these symptoms if your brain and heart are not getting enough oxygen.

How is respiratory failure diagnosed?

Your health care provider will diagnose respiratory failure based on

  • Your medical history
  • A physical exam, which often includes
    • Listening to your lungs to check for abnormal sounds
    • Listening to your heart to check for arrhythmia
    • Looking for a bluish color on your skin, lips, and fingernails
  • Diagnostic tests, such as
    • Pulse oximetry, a small sensor that uses a light to measure how much oxygen is in your blood. The sensor goes on the end of your finger or on your ear.
    • Arterial blood gas test, a test that measures the oxygen and carbon dioxide levels in your blood. The blood sample is taken from an artery, usually in your wrist.

Once you are diagnosed with respiratory failure, your provider will look for what is causing it. Tests for this often include a chest x-ray. If your provider thinks you may have arrhythmia because of the respiratory failure, you may have an EKG (electrocardiogram). This is simple, painless test that detects and records your heart's electrical activity.

What are the treatments for respiratory failure?

Treatment for respiratory failure depends on

  • Whether it is acute (short-term) or chronic (ongoing)
  • How severe it is
  • What is causing it

Acute respiratory failure can be a medical emergency. You may need treatment in intensive care unit at a hospital. Chronic respiratory failure can often be treated at home. But if your chronic respiratory failure is severe, you might need treatment in a long-term care center.

One of the main goals of treatment is to get oxygen to your lungs and other organs and remove carbon dioxide from your body. Another goal is to treat the cause of the condition. Treatments may include

  • Oxygen therapy, through a nasal cannula (two small plastic tubes that go in your nostrils) or through a mask that fits over your nose and mouth
  • Tracheostomy, a surgically-made hole that goes through the front of your neck and into your windpipe. A breathing tube, also called a tracheostomy, or trach tube, is placed in the hole to help you breathe.
  • Ventilator, a breathing machine that blows air into your lungs. It also carries carbon dioxide out of your lungs.
  • Other breathing treatments, such as noninvasive positive pressure ventilation (NPPV), which uses mild air pressure to keep your airways open while you sleep. Another treatment is a special bed that rocks back and forth, to help you breathe in and out.
  • Fluids, often through an intravenous (IV), to improve blood flow throughout your body. They also provide nutrition.
  • Medicines for discomfort
  • Treatments for the cause of the respiratory failure. These treatments may include medicines and procedures.

If you have respiratory failure, see your health care provider for ongoing medical care. Your provider may suggest pulmonary rehabilitation.

If your respiratory failure is chronic, make sure that you know when and where to get help for your symptoms. You need emergency care if you have severe symptoms, such as trouble catching your breath or talking. You should call your provider if you notice that your symptoms are worsening or if you have new signs and symptoms.

Living with respiratory failure may cause fear, anxiety, depression, and stress. Talk therapy, medicines, and support groups can help you feel better.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for RESPIRATORY FAILURE

RESPIRATORY FAILURE treatment research studies

Thyroid clinical trials, surveys and public health registries


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Thyroid Side Effects

Fatigue (48)
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Product Formulation Issue (23)
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Blood Pressure Increased (17)
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Depression (17)
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Recent Reviews

I have been getting these little blister sores that bust and turn into scap little sores. I have noticed it since about a month or so after found out my thyroid is not working right. Could this be a side effect from the medication

I have only been on it five days, it is better than nothing so far. My own thyroid production took a downfall and I am used to Armour Thyroid which has been my doctor's first choice for years. I was told by my European Doctor that Synthyroid is jus

I'm losing a lot of weight. Was 110 when started on Armour. Lost 15 lbs in one year. Take 90

In the Spring of 2008 I went to my PCP for allergy symptoms, and when he felt my neck glands to make sure that I didn't have something similiar to strept throat, he said that's the biggest Thyrioid I've ever felt, well 2 weeks later the surgeon was r

My husbadn is almost 52, and he has been very ill with a chronic GI condition for the last 12 months. He has been in and out of the hospital and had his gull bladder and appendix removed. They still have no diagnosis for the GI problems. Now last wee

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i had heart failure last august 2010, among other tablets i have been taking emconcor. i wonder whether these tablets are responsible for making my limbs feel weak, and lightheaded.

<b>Describe Your Tazocin Experience Here:</b>after it was administered to my farther in hospital for the first time on day he was due to be released he had a cardiac arrest with multiple organ failure and subsequently died

had my first shot of aranesp one week ago for anemia , i have renal failure, I'm 62 , and I am a working nurse. I will be getting aranesp every 2 weeks if my blood count is less than 11. well out of no where I have becom

2 weeks after second infusion for Hodgkin's Lymphome (& RA), I had an extreme respiratory problem (BOOP). I was hospitalized twice & had high steroid does IV along with IV antiobiotics administered. After 1 year of decreasing steroi

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A report-I had a suppression dose of Macrobid; after 8 months much worse and after a year in fulminant hepatic failure leading to a transplant. How can these changes be spotted for women like me.

AGGRENOX SIDE EFFECT. PATIENT WAS PRESCRIBED PLAVIX. AGGRENOX WAS SUBSTITUTED. PATIENT SUFFERED ACUTE RESPIRATORY FAILURE AND CARDIO-RESPIRATORY ARREST. PATIENT WAS HOSPITALIZED. PATIENT DIED 3/29/09.

An injection of toradol in hattiesburg Forrest general Hospital resulted in complete Kidney failure with 5 days in hospital. medical records are available if proof is needed. recovered

Been on drug since 1/20/11. er mid feb w/diagnosis of acid reflux; as time went on i have had excessive gas, leg/ankle swelling; loss of appetite; dry cough; sleepiness; lack of energy; out of breath; docs say heart failure---this is an 85 yr old man

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RESPIRATORY FAILURE Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Thyroid Hormone Dose Adjustment in Pregnancy
Conditions: Pregnancy;   Hypothyroidism
Interventions: Drug: Anticipatory dose increase of levothyroxine;   Drug: levothyroxine
Outcome Measures: proportion of patients in each treatment arm euthyroid through gestation;   the proportion of patients in each arm who required, and the gestation week at which, levothyroxine dose adjustments (either increased or decreased) occurred to maintain a euthyroid state;   Determination of the necessary frequency of serum evaluation of TSH during the first half of gestation.
2 Recruiting Study of Optimal Replacement of Thyroxine in the Elderly
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Participant's acceptability of study design and willingness to enter study;   Participant recruitment rate;   Time to achieve desired TSH levels;   Medication compliance;   The acceptability of three patient completed questionnaires;   Assessment of mobility;   Change in specific cardiovascular risk factors;   Measure of risk of falls
3 Recruiting Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulation.
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine sodium new formulation
Outcome Measures: The proportion of patients that do not need a change of dose.;   The magnitude of the change in daily dose needed.;   Proportion of patients that obtained a thyroid stimulating hormone between 0.4-2.5 mU/L;   Change from baseline serum thyroid stimulating hormone (in mIU/L and percentage).
4 Unknown  Thyroxin Treatment in Sub Clinical Hypothyroidism, on the Apnea Hypopnea Index Score, Lipids and Highly Sensitive CRP
Condition: Dyslipidemia
Interventions: Drug: levothyroxine;   Drug: sugar pill
Outcome Measures: Effect of the treatment of subclinical hypothyroidism on the apnea hypopnea index (AHI) score.;   Effect of the treatment of subclinical hypothyroidism on the lipid profile in patient with dyslipidemia and on hs-CRP
5 Recruiting Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: Rate of First CVD Events, CVD Mortality and All-cause Mortality;   Change in Serum Lipid Levels;   Change in Thickness of Blood Vessel Wall;   Change in Oxidative Stress and Chronic Inflammatory Factors Associated with Atherosclerosis
6 Recruiting Desiccated Thyroid Extract and Levothyroxine for Hypothyroidism Treatment
Condition: Primary Hypothyroidism.
Interventions: Drug: Levothyroxine;   Drug: Desiccated thyroid extract
Outcome Measures: thyroid-symptom questionnaire;   Wechsler Memory Scale-Version IV (WMS-IV);   Biochemical measures
7 Recruiting Thyroid Hormone Replacement for Subclinical Hypothyroidism
Condition: Subclinical Hypothyroidism
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measures: Fatal and non-fatal cardiovascular events;   Thyroid-specific quality of life;   Health-related quality of life;   Handgrip strength;   Executive cognitive function;   Total mortality;   Basic Activities of Daily Living;   Extended activities of daily living;   Haemoglobin
8 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Change in non-HDL cholesterol from baseline at 6, 12 and 18 months.;   Change in quality of life from baseline at 6, 12 and 18 months.
9 Recruiting L-Thyroxine Supplementation for Preterm Newborns Less Than 32 Weeks of Gestation With Hypothyroxinemia
Condition: Hypothyroxinemia
Interventions: Drug: L-Thyroxine;   Drug: water
Outcome Measures: Neurodevelopmental outcome;   Morbidity associated with management of newborns < 32 WG with hypothyroxinemia
10 Recruiting Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: change in lipid profile;   change in thickness of blood vessel wall;   change in endothelial function;   change of adipocytokines;   Change of Oxidative Stress and Chronic Inflammatory Factors Related with Atherosclerosis
11 Recruiting Thyroid Study Type 2 Diabetes Mellitus (T2DM)
Conditions: Diabetes;   Hypothyroidism
Intervention: Drug: Euthyrox (levothyroxine)
Outcome Measures: Thyroid hormone-induced change in whole body insulin sensitivity (change in insulin-stimulated glucose disposal) and muscle mitochondrial function;   Thyroid hormone-induced change of lipid content in skeletal muscle and liver and brown adipose tissue activity
12 Recruiting Early Levothyroxine Post Radioactive Iodine
Condition: Graves' Disease
Intervention: Drug: Levothyroxine
Outcome Measures: Prevention of overt hypothyroidism;   Quality of Life
13 Recruiting Antithyroid Drug Treatment of Thyrotoxicosis in Young People
Condition: Paediatric Thyrotoxicosis
Interventions: Procedure: Block and Replace;   Procedure: Dose Titration;   Drug: carbimazole;   Drug: propylthiouracil;   Drug: thyroxine
Outcome Measures: Remission rate as defined by patients who are biochemically euthyroid at the end of the 6 year study period.;   Biochemical control as reflected by blood TSH and thyroxine levels;   The frequency of adverse events on the 2 treatment regimens.
14 Recruiting The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma
Conditions: Thyroid Carcinoma;   Hypothyroidism
Interventions: Other: Black Coffee;   Other: Coffee with Milk;   Other: Black Tea;   Other: Water
Outcome Measures: Change in TSH (thyrotropin-stimulating-hormone) with each beverage type;   Change in TSH with various beverages;   Change in total T4 with each beverage type;   Change in free T4 with each beverage type;   Change in total T3 with each beverage type
15 Not yet recruiting Thyroid Hormones Treatment in Asthma Exacerbation
Condition: Asthma
Interventions: Drug: IV thyroxin;   Drug: Placebo
Outcome Measures: time to normalization of PEF (peak expiratory flow);   Length of stay;   Time to oxygenation;   heart rate;   respiratory rate
16 Recruiting Selenium Supplementation in Pregnancy
Conditions: Pregnancy;   Infertility;   Auto-immune Thyroiditis
Interventions: Dietary Supplement: Selenium;   Other: Sugar Pill Placebo;   Other: Selenium + L-Thyroxine (LT4);   Other: Sugar Pill Placebo + L-Thyroxine (LT4)
Outcome Measures: Changes in TPOab and/or Tgab;   Changes in thyroid volume and echogenicity;   Changes in thyroid hormones (TSH, FT4, FT3);   Evaluation of Maternal risks;   Evaluation of Infant risks;   Changes in of quality of life;   Evaluation of Health Services:;   Changes in the selenium-dependent antioxidant enzyme glutathione peroxidase;   Changes in implantation and pregnancy rates
17 Recruiting The TRUST Study - Depression Substudy
Conditions: Subclinical Hypothyroidism;   Depression
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measure: Change from baseline in 15-items Geriatric Depression Scale
18 Recruiting Preconceptional Thyroid Screening and Childhood Nerocognitive Function
Condition: Hypothyroidism
Intervention: Procedure: levothyroxine
Outcome Measures: Offspring neurocognitive assessment at 0-3 yrs;   Offspring IQ assessment at 0-3 yrs;   Incidence of neonatal hypothyroid and complications
19 Unknown  The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children
Conditions: Child Development Disorders;   Pregnancy;   Subclinical Hypothyroidism
Intervention:
Outcome Measure:
20 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
Outcome Measures: GMDS ( Griffiths Mental Development Scale);   BL (Brunet Lezine revised scale)