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RESTLESSNESS and Seroquel

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RESTLESSNESS Symptoms and Causes

For most adults, moderate alcohol use is probably not harmful. However, about 18 million adult Americans have an alcohol use disorder (AUD). This means that their drinking causes distress and harm. It includes alcoholism and alcohol abuse.

Alcoholism, or alcohol dependence, is a disease that causes

  • Craving - a strong need to drink
  • Loss of control - not being able to stop drinking once you've started
  • Physical dependence - withdrawal symptoms
  • Tolerance - the need to drink more alcohol to feel the same effect

With alcohol abuse, you are not physically dependent, but you still have a serious problem. The drinking may cause problems at home, work, or school. It may cause you to put yourself in dangerous situations, or lead to legal or social problems.

Another common problem is binge drinking. It is drinking about five or more drinks in two hours for men. For women, it is about four or more drinks in two hours.

Too much alcohol is dangerous. Heavy drinking can increase the risk of certain cancers. It can cause damage to the liver, brain, and other organs. Drinking during pregnancy can harm your baby. Alcohol also increases the risk of death from car crashes, injuries, homicide, and suicide.

You may have an AUD if you can answer yes to two or more of these questions:

In the past year, have you

  • Ended up drinking more or for a longer time than you had planned to?
  • Wanted to cut down or stop drinking, or tried to, but couldn't?
  • Spent a lot of your time drinking, or recovering from drinking?
  • Felt a strong need to drink?
  • Found that drinking - or being sick from drinking - often interfered with your family life, job, or school?
  • Kept drinking even though it was causing trouble with your family or friends?
  • Given up or cut back on activities that you enjoyed just so you could drink?
  • Gotten into dangerous situations while drinking or after drinking? Some examples are driving drunk and having unsafe sex.
  • Kept drinking even though it was making you feel depressed or anxious? Or when it was adding to another health problem?
  • Had to drink more and more to feel the effects of the alcohol?
  • Had withdrawal symptoms when the alcohol was wearing off? They include trouble sleeping, shakiness, irritability, anxiety, depression, Restlessness, nausea, and sweating. In severe cases, you could have a fever, seizures, or hallucinations.

If you have any of these symptoms, your drinking may already be a cause for concern. The more symptoms you have, the more serious the problem is. If you think you might have an AUD, see your health care provider for an evaluation. Your provider can help make a treatment plan, prescribe medicines, and if needed, give you treatment referrals.

NIH: National Institute on Alcohol Abuse and Alcoholism

Check out the latest treatments for RESTLESSNESS

RESTLESSNESS treatment research studies

Seroquel clinical trials, surveys and public health registries


Find Drug Side Effect reports



Seroquel Side Effects

Diabetes Mellitus (6103)
Type 2 Diabetes Mellitus (3575)
Insomnia (2241)
Pancreatitis (1939)
Blood Cholesterol Increased (1705)
Weight Increased (1696)
Obesity (1197)
Diabetes Mellitus Inadequate Control (1084)
Diabetic Ketoacidosis (1083)
Depression (1046)
Hyperglycaemia (1037)
Diabetic Neuropathy (1010)
Somnolence (997)
Anxiety (972)
Malaise (971)
Off Label Use (948)
Feeling Abnormal (830)
Blood Triglycerides Increased (806)
Suicidal Ideation (805)
Diabetic Coma (803)
Convulsion (757)
Death (753)
Neuropathy Peripheral (744)
Tardive Dyskinesia (696)
Dizziness (683)
Type 1 Diabetes Mellitus (667)
Hyperlipidaemia (662)
Chest Pain (641)
Hypertension (632)
Fall (631)
Fatigue (612)
Headache (611)
Overdose (594)
Suicide Attempt (564)
Back Pain (547)
Bipolar Disorder (519)
Nausea (492)
Agitation (488)
Tremor (449)
Dyspnoea (437)
Confusional State (432)
Loss Of Consciousness (403)
Vomiting (395)
Mental Disorder (383)
Blood Glucose Increased (382)
Abdominal Pain (378)
Cardiac Disorder (373)
Cerebrovascular Accident (370)
Asthenia (368)
Aggression (359)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

After taking 300 mgm a day of seroquel, I gained 30 lbs over a period of 3 months with all the symptoms of metabolic syndrome. Now I am unable to lose that weight even though I no longer take the medicati9on

After taking Seroquel for about two weeks, I came down with quite serious laryngitis. I've had it for about a week and it is not getting any better. I don't have a cold or sore throat and can't think of any other reason for this. Could this be cau

Check out my med list; kind like a handbook isn't it?

Doing range of motion exercises on the neck with the head is an excellent way of treating cronic insomonia. >:o O:-)

I also had to increase the weight for my pendulum exercises to make easier to adjust my shoulder. :)

I also had to raise my arms up and down behind my head in order to adjust the top of my neck.

I am having the same experience. I also had been taking Seroquel for about 2 weeks when I began to lose my voice. I am researching today because my laryngitis is practically 100% today.

I Believe Seroquel killed my husband. He tried to get help with depression and suiside and seroquel made him worse. I totally believe this awful drug killed him and he was only 45. I miss him terribly and hope I can help to keep suiside patients off

I had such severe side effects I thought I was going insane. My husband even got out the video camera to show me how bad it was. I rocked and rocked back and forth, my entire body shook involuntarily, I paced, I didn't sleep,I couldn't rest or relax

I have been taking seroquel and zyban. i have two children, and trying for another. When i gave birth to my children i was on other medication. Since on this combination of seroquel and zyban i cannot seem to ovulate.

I am Aged 46, and have been On Kliovance for 6 weeks, have gained weight, bloated stomach, extreme tiredness,aching bones, restlessness...,edgy...The sweats have gone but thats all.I find there is not enough relevant information for women f

.Skin burning, restlessness, restlessness of arms and legs, Diarrohea.

16, ADHD, hate my dependency on adderall, depression, random euphoria, aggression, slight tics, restlessness, irritability, antisocial, anger, all day the only thing i'm able to think about is the list of shit that needs to get done and if it's a lon

2 patients given thiocolchicoside reported of muscular stiffness,uneasiness,insomnia,breathlessness and feeling of restlessness, 2 out of 5 patients have reported such experiences after consuming thiocolchicoside.i strongly recommend to withdraw this

After taking Ganatone 50 I sufferpain in abdomen, chest discomfort and some restlessness in the body.

Day 1: Smoked as per usual, VERY difficult to fall asleep d/t pruritis, RLS, as well as geralized restlessness Day 2 : Smoking decreased by half. Did not get much pleasure from it...nor anything else. Felt like a complete zombie,

Ever since i stated taking Gycopyrrolate 2mg i stated to haves restlessness, itchy eyes, congestion, awful imsomina.

First two months were fine but I have noticed recently after a day or two of not taking them that I have severe restlesnness in my legs and twitching, tingling feelings running up and down my legs at night. Insomnia when taking them. The restlessness

Had cortisone injections in both shoulders one week ago. Within 24 hours was experiencing more severe pain in shoulders, insomnia and headaches. Within 3 days above symptoms continuing also bloating, nausea, anxiety, restlessness,

Hi, i am diagnosed with anxiety and deppresion, i have been taking molipaxin for 4 month now and i have sleepless nights, blurred vision, restlessness and i am very hyper active. was on c lifts and could not cope as i felt druged permanatly and dizyy

RESTLESSNESS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine
Conditions: Dementia;   Delirium
Interventions: Drug: Quetiapine 25 mg gel applied topically;   Drug: Quetiapine 25 mg tablet by mouth;   Drug: Quetiapine 25 mg rectal suppository
Outcome Measures: Serum quetiapine levels after topical application (Visit 1);   Serum quetiapine levels after oral administration (Visit 2);   Serum quetiapine levels after rectal administration (Visit 3)
2 Unknown  A Study to Evaluate the Efficacy and Safety of Flexible Dose of Quetiapine Fumarate (Seroquel) Switching From Other Drugs in the Treatment of Acute Manic Patients With Bipolar Disorder
Condition: Bipolar Disorder
Intervention: Drug: quetiapine fumarate tablet (Seroquel)
Outcome Measures: The primary efficacy variable for this study is the YMRS total score change from baseline to Day 28 (LOCF).;   To evaluate the effectiveness of quetiapine fumarate;   To evaluate the relationship between the serum brain-derived neurotrophic factor and quetiapine fumarate;   To evaluate the safety and tolerability of quetiapine fumarate
3 Unknown  Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS)
Conditions: Abnormal Mental State;   Schizophrenia
Intervention: Drug: Quetiapine(Seroquel-XR) 50~800mg a day
Outcome Measures: California Verbal Learning Test;   verbal & spatial 2-back test, Digit Span, 3-7 CPT, WCST, Rey-CFT, TMT A & B, COWAT, SOPS, PANSS, SAS, PAS, AIHQ, BIS
4 Unknown  Efficacy and Safety of Utapine vs. Seroquel in Patients With Bipolar Mania
Conditions: Bipolar, Mania;   Utapine;   Seroquel
Interventions: Drug: Utapine;   Drug: Seroquel
Outcome Measure:
5 Recruiting The Effect of Quetiapine XR in Depressive Patients Showing Aberrant N100 Amplitude Slope
Condition: Major Depressive Disorder
Interventions: Drug: SSRI monotherapy;   Drug: Seroquel XR adjunctive
Outcome Measures: Change from baseline in HDRS scale;   Change from baseline in CGI, BDI, and YMRS scales
6 Unknown  Pilot Study to Evaluate the Efficacy and Safety of Quetiapine Fumarate Instant-Release (Seroquel IR) in Controlling Agitation and Aggressive Symptoms in the Acute Treatment of Patients With Schizophrenia
Condition: Acute Schizophrenia
Interventions: Drug: Quetiapine fumarate;   Drug: Haloperidol
Outcome Measures: The primary objective of this study is to evaluate the efficacy of quetiapine fumarate in improving agitation and aggression symptoms for the schizophrenic patients;   The response rate of quetiapine in improving agitation and aggression symptoms - the efficacy of quetiapine - the safety and tolerability of quetiapine - differences between quetiapine and haloperidol
7 Unknown  Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry
Conditions: Schizophrenia;   Psychosis
Intervention: Drug: Quetiapine XR
Outcome Measures: The primary efficacy variable is the change in aggression between admission and day 8 of treatment with Quetiapine XR as measured by the OAS.;   Measuring psychotic symptomatology change from baseline in BPRS-Total Score in aggressive, psychotic patients managed with Quetiapine XR;   Measuring the incidence of adverse events (including Extrapyramidal symptoms) by the change from baseline in SAS and BAS and subjective reports;   Measuring the incidence of concomitant benzodiazepine and other permitted medication use
8 Unknown  Trial of Quetiapine in Anorexia Nervosa
Condition: Anorexia Nervosa
Intervention: Drug: Quetiapine
Outcome Measures: Primarily we will seek to show that Quetiapine is superior to placebo in terms of reducing core eating disorder symptoms on the Yale-Brown-Cornell Eating Disorder Scale (YBC-EDS) and the Eating Disorders Inventory-2.;   We seek to show that Quetiapine is superior to placebo in reducing anxiety, depression, obsessionality, or weight gain in patients with AN. We also will seek to show that Quetiapine is superior to placebo at reducing positive and negative symptoms.
9 Recruiting Quetiapine Pharmacotherapy for Cannabis Dependence
Condition: Cannabis Dependence
Interventions: Drug: Quetiapine;   Drug: Placebo
Outcome Measures: Marijuana Use;   Marijuana Abstinence;   Urine toxicology;   Marijuana withdrawal symptoms;   Marijuana craving;   Sleep disturbance
10 Unknown  Brain Derived Neurotrophic Factor as a Predictor of Response to Treatment in Bipolar Depression and Mania: 16-weeks Follow-up With Quetiapine XR
Condition: BIPOLAR DISORDER
Intervention: Drug: quetiapine
Outcome Measures: Efficacy of quetiapine as a treatment for acute mania and depression, and of as a manutence treatment.;   Assess the pharmacodynamics of quetiapine by neurotrophins in blood samples.
11 Recruiting Gao Bipolar Spectrum Lithium/Quetiapine Study
Condition: Bipolar Disorder
Interventions: Drug: Lithium;   Drug: Quetiapine
Outcome Measures: Time to study discontinuation;   Lithium vs. Quetiapine effects on general cardiovascular disease risk and role effects on general cardiovascular disease risk and role impairment
12 Not yet recruiting Safety and Tolerability of Quetiapine in Multiple Sclerosis
Condition: Multiple Sclerosis
Intervention: Drug: Extended-release quetiapine fumarate
Outcome Measures: Dose-limiting toxicity;   Adverse events
13 Recruiting Post-Traumatic Stress Disorder (PTSD) and Seroquel
Condition: Post-Traumatic Stress Disorder
Intervention: Drug: Seroquel
Outcome Measures: The primary outcome will be the change from baseline in PTSD symptomatology at the week 8 timepoint.;   The secondary outcome will be the change from baseline in PTSD symptomatology at the Week 8 timepoint.
14 Recruiting European Drug Utilization Study
Condition: Major Depressive Disorder (MDD)
Intervention:
Outcome Measures: Patient age (mean and range);   Patient gender (%);   Diagnosis for which Seroquel XR was prescribed (% of Major Depressive Disorder- MDD);   Patients hospitalized for any psychiatric condition (n, %);   Daily dose of Seroquel XR (mode and range);   Patient referral pathway (%);   Participating psychiatrist practice setting (%);   Percent of patients experiencing psychotic symptoms at initiation of Seroquel XR (n, %)
15 Unknown  Effects of Seroquel XR on Sleep Architecture in Patients With Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Quetiapine Fumarate Extended Release;   Other: healthy control
Outcome Measures: change from baseline Pittsburgh Quality Index total scores at 4 weeks;   change from baseline Pittsburgh Quality Index total scores at 2 weeks;   change from baseline Pittsburgh Quality Index total scores at 4 days;   change from baseline in sleep architecture measured using polysomnography at 4 weeks;   number of participants with adverse events
16 Recruiting Efficacy of Quetiapine for Pediatric Delirium
Condition: Delirium
Interventions: Drug: quetiapine;   Other: Placebo
Outcome Measures: Time to first resolution of delirium;   Total ICU days with delirium
17 Unknown  Heart Rate Changes in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine
Conditions: Schizophrenia;   Bipolar
Intervention: Drug: Aripiprazole; Quetiapine
Outcome Measure:
18 Recruiting Trial Comparing Haloperidol, Quetiapine and Placebo in the Pharmacological Treatment of Delirium
Condition: Delirium
Interventions: Drug: Quetiapine;   Drug: Haloperidol;   Drug: Placebo
Outcome Measures: Time to first resolution of delirium;   Days in delirium during the study;   Duration of delirium;   Severity of delirium (highest Nu-DESC score, mean episode Nu-DESC score);   ICU and hospital mortality;   ICU and hospital length of stay;   Length of mechanical ventilation;   Time spent deeply sedated (RASS <3);   Episodes of subject-initiated device removal;   Use of haloperidol therapy (including total dose in haloperidol equivalents during the study, number of doses, number of days of therapy, use of rescue IV haloperidol);   Average daily and maximum total antipsychotic drug dose in haloperidol equivalents;   Duration of study drug administration;   Use of benzodiazepines;   Use of opioids;   QTc prolongation;   Extrapyramidal symptoms;   Neuroleptic malignant syndrome
19 Recruiting Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania
Condition: Bipolar Disorder
Interventions: Drug: Lithium;   Drug: Valproate;   Drug: Oxcarbazepine;   Drug: Quetiapine;   Drug: Olanzapine;   Drug: Ziprasidone
Outcome Measures: Change from baseline in Young Mania Rating Scale at 2 weeks and 6 weeks;   rate of dropout (treatment discontinuation);   Clinical Global Impressions (CGI) Scale;   Brief Psychiatric Rating Scale;   Global Assessment Scale;   Treatment Emergent Symptom Scale;   Hamilton Anxiety Rating Scale;   Hamilton Depression Rating Scale
20 Unknown  Quetiapine for the Treatment of Insomnia in Alzheimer's Disease
Conditions: Alzheimer's Disease;   Insomnia
Intervention: Drug: quetiapine
Outcome Measures: The primary objective is to determine whether quetiapine can increase total sleep time and reduce time awake in patients with AD and sleep disturbance.;   Dose-response relationship of quetiapine and sleep in AD patients?;   Are there sleep architecture changes from quetiapine?;   Do the primary sleep variables change relative to placebo at any weekly time or dose point?;   Are caregivers, blind to treatment status, able to detect changes in sleep quality in the patients for quetiapine relative to placebo?;   Does quetiapine used at single bedtime dosing for potential nighttime soporific effect have a measurable impact on neuropsychiatric symptoms other than insomnia?