PatientsVille.com Logo

RHEUMATOID ARTHRITIS and Diclofenac

PatientsVille

RHEUMATOID ARTHRITIS Symptoms and Causes

Rheumatoid arthritis (RA) is a form of arthritis that causes pain, swelling, stiffness and loss of function in your joints. It can affect any joint but is common in the wrist and fingers.

More women than men get rheumatoid arthritis. It often starts in middle age and is most common in older people. You might have the disease for only a short time, or symptoms might come and go. The severe form can last a lifetime.

Rheumatoid arthritis is different from osteoarthritis, the common arthritis that often comes with older age. RA can affect body parts besides joints, such as your eyes, mouth and lungs. RA is an autoimmune disease, which means the arthritis results from your immune system attacking your body's own tissues.

No one knows what causes rheumatoid arthritis. Genes, environment, and hormones might contribute. Treatments include medicine, lifestyle changes, and surgery. These can slow or stop joint damage and reduce pain and swelling.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for RHEUMATOID ARTHRITIS

RHEUMATOID ARTHRITIS treatment research studies

Diclofenac clinical trials, surveys and public health registries


Find Drug Side Effect reports



Diclofenac Side Effects

Renal Failure Acute (154)
Abdominal Pain (139)
Diarrhoea (136)
Vomiting (128)
Dyspnoea (103)
Haemoglobin Decreased (103)
Gastrointestinal Haemorrhage (102)
Nausea (88)
Blood Creatinine Increased (88)
Anaemia (86)
Malaise (83)
Dehydration (82)
Pruritus (79)
Abdominal Pain Upper (77)
Blood Urea Increased (76)
Dizziness (72)
Gastric Ulcer (68)
Gastrointestinal Disorder (68)
Haematemesis (64)
Anaphylactic Reaction (62)
Pyrexia (61)
Erythema (60)
Fatigue (60)
Pain (60)
Hypotension (57)
Melaena (56)
Embolia Cutis Medicamentosa (54)
Chest Pain (54)
Arthralgia (53)
Rash (53)
Oedema Peripheral (51)
Asthenia (50)
Loss Of Consciousness (49)
Alanine Aminotransferase Increased (49)
Fall (48)
Headache (47)
Blood Alkaline Phosphatase Increased (47)
Metabolic Acidosis (46)
Gastritis (46)
Renal Failure (45)
Cardiac Arrest (44)
Confusional State (43)
Back Pain (43)
C-reactive Protein Increased (43)
Convulsion (43)
Urticaria (43)
Blood Pressure Decreased (41)
Weight Decreased (41)
Peritonitis (41)
Aspartate Aminotransferase Increased (40)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

<span style='color: #808080;'>Took Diprophos for rheumatoid arthritis. Side effects: insomnia for 2 nights, perspiring during night, redness in face. Increased need to urinate.

Dear one and all, i am a 20yrs married girl, in India I am not well educated so please dont mind if i wrote any mistakes in English. is it possible if my husband having the rheumatoid artritis then it goes to my baby( now i am 8 th month Preg

I injected diclofenac injection without any accident

I've had arthritis for about 7 years. I am getting pains in my feet that feel like an ant has just bitten me. This is new.

If he was born with it it is heiriditary

Im general practioner i gave on intra mascular diclofenac for fever and body and about 8 or less he is dead inspite of using diclofeac tablet before and there is no prblem

Insomnia. hypertension

Mechanism of tocilizumab to help rheumatoid arthritis

What is an effective alternative to diclofenac ?

What is Diclac Gastro-resistant tablets and for what they are?

Arthritis Treatment Safe, Natural Cure for Adults. Synflex Liquid Glucosamine, Rheumatoid Arthritis Joint Pain Relief Remedy, Diet Supplements. Synflex, Glucosamine for Dogs. Free Shipping! &lt;a href='http://www.healthyjointcare.com/'&g

&lt;!--StartFragment--&gt; I have advanced Rheumatoid Arthritis. My Left wrist swelled painfully. Had a negative X-ray so Dr (fully informed for current drug regimens and allergies--Aspirin, Penicillin, Thoradamides, Ornate, Iodine, Latex)

<b>Describe Your Pradaxa Experience Here:</b>itching that last five minutes and goes away i have swelled knee pain also arthritis

<b>My wife had a stroke in 2002. The doctor prescribed meloxicam 15mg in July 2010 for arthritis. In August 2010 she had a silent heart attack diminishing heart pumps to 25%.</b>

<span style='color: #808080;'>Took Diprophos for rheumatoid arthritis. Side effects: insomnia for 2 nights, perspiring during night, redness in face. Increased need to urinate.

12 weeks on Sulfasalazine for Rheumatoid Arthritis and I have more joint pain than I ever had more fatigue and the most horrendous hot flashes all day long and at night sweats as well .... the nausea too is horrible .....

After being on Fosamax for approximately four and one half years suddenly I developed severe medial bilateral knee pain. Have pain when walking down and up stairs. I have NO history of arthritis, no inflammation or redness at the location of pain. I

After being on zolidex for endometriosis i now hae rheumatoid arthritis and other problems being investigated i feel cheated for a few months of less pain im now heading for a lifetime of more pain and operations.

After taking novatrex for over 8 weeks for rhumathiod arthritis or psoriatic arthritis i could hardly breathe and my voice was hoarse , i also was spitting lots os foamy stuff ,

Arthritis and dysfunction of the temporomandibular joint. Alleviated by cessation (over cca. 8 days). Worsened again by taking champix again.

RHEUMATOID ARTHRITIS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Analgesic Efficacy and Safety of Voltaren Gel (1% Diclofenac Sodium) Compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness
Condition: Delayed Onset Muscle Soreness
Interventions: Drug: 1% Diclofenac sodium gel;   Drug: Placebo
Outcome Measure: To assess analgesic efficacy of Topical Voltaren® gel compared to placebo
2 Recruiting Safety Study of Flector Patch in Children With Minor Soft Tissue Injuries
Condition: Athletic Injuries
Intervention: Drug: Diclofenac hydroxyethylpyrrolidine
Outcome Measures: Dermatologic assessment at the patch application site;   Investigator assessment of the global response to therapy on a 5-point scale;   Patient assessment of pain on a 6-point scale;   Plasma concentration of Diclofenac
3 Recruiting Study Comparing a Generic Diclofenac Sodium Topical Gel, 1% to Voltaren in the Treatment of Subjects With Osteoarthritis of the Knee
Condition: Osteoarthritis
Interventions: Drug: Diclofenac Sodium Topical Gel, 1%;   Drug: Voltaren Topical Gel, 1%;   Drug: Vehicle Diclofenac Sodium Topical Gel
Outcome Measure: WOMAC Pain Score
4 Recruiting Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%
Conditions: Knee Pain Chronic;   Knee Injuries
Interventions: Drug: Diclofenac Cream 8%;   Drug: Diclofenac Gel 1%
Outcome Measure: Descrete Response Scale Pain Scores
5 Unknown  Comparison of the Effect of Etoricoxib and Diclofenac on Early Morning Activity in Rheumatoid Arthritis (RA)
Condition: Rheumatoid Arthritis
Interventions: Drug: Etoricoxib;   Drug: Diclofenac
Outcome Measures: To explore the effect of Etoricoxib compared to Diclofenac on physical activity in RA subjects with Early morning pain and stiffness.;   To explore the effect of Etoricoxib compared to Diclofenac on average daily pain scores, fatigue scores, and quality of life.
6 Recruiting Efficacy of Diclofenac on Pain During Endometrial Sampling
Condition: Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
Interventions: Drug: Diclofenac Potassium;   Drug: Folic Acid
Outcome Measure: Effectiveness of Diclofenac Potassium for additional acute pain control in patient undergoing fractional curettage under paracervical block due to abnormal uterine bleeding
7 Recruiting A Multicenter Efficacy Study of a Diclofenac+Menthol Gel in Subjects With Ankle Sprain
Condition: Ankle Sprain
Interventions: Drug: 1% Diclofenac sodium plus 3% menthol;   Drug: 1% Diclofenac sodium plus 0.09% menthol;   Drug: 3% menthol;   Drug: Placebo with 0.09% menthol gel
Outcome Measures: AUC (1-3 days);   Pain Intensity Difference (PID) on movement;   PID at rest;   Pain Relief Score (PRS);   Sum of Pain Intensity Difference (SPID);   Time of Onset of Pain Relief (TOPR);   Time of Onset of Meaningful Pain Relief (TOMR);   Time of Onset of Cooling Sensation (TOCS);   Total Pain Relief (TOTPAR);   Skin Temperature;   Ankle Swelling;   Time to complete Recovery;   Patient's Global Assessment in Response to Treatment (PGART);   Adverse events (AEs)
8 Recruiting Effects of Topical Diclofenac on Tumor Metabolism
Condition: Actinic Keratoses
Intervention: Drug: 3% Diclofenac in 2.5% hyaluronic acid gel
Outcome Measures: Lactate level in skin biopsies of actinic keratoses;   Lactate level in skin biopsies of healthy skin in a subpopulation;   Glycolysis-relevant proteins evaluated using PCR and Westernblot techniques;   Metabolic changes (e.g. glucose, amino acids)
9 Not yet recruiting Supersaturation and Precipitation of Diclofenac in the Stomach of Healthy Volunteers
Condition: Supersaturation and Precipitation in the Stomach
Intervention: Drug: Diclofenac potassium 50 mg
Outcome Measure: Area under the Concentration - Time Curve
10 Recruiting Diclofenac for Submassive PE
Condition: Pulmonary Embolism
Interventions: Drug: Diclofenac;   Drug: Placebo
Outcome Measure: Right ventricular dysfunction assessed by transthoracic echocardiography
11 Unknown  Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty
Conditions: Coxarthrosis;   Arthroplasties Hip Replacement;   Perioperative Blood Loss
Interventions: Drug: Etoricoxib;   Drug: Diclofenac
Outcome Measure:
12 Recruiting Efficacy and Safety of Diclofenac DDEA 2.32 % in Patient Suffering From Knee Osteoarthritis (OA)
Condition: Osteoarthritis, Knee
Intervention: Drug: Diclofenac diethylamine, DDEA 2.32% gel
Outcome Measures: Measure: Pain On Movement (POM);   Measure POM regarding onset of efficacy
13 Recruiting Intramuscular Diclofenac in the Prevention of Post-ERCP Pancreatitis
Condition: Post ERCP Pancreatitis
Interventions: Drug: Diclofenac;   Drug: normal saline
Outcome Measure: Incidence of post ERCP pancreatitis
14 Not yet recruiting In Vivo Inhibition Profile of CYP2C9 by Pineapple Juice
Condition: Healthy Volunteers
Intervention: Dietary Supplement: pineapple juice (Carrefour n°1) 500 ml/day 5 days
Outcome Measures: a) AUC 4-OH-Diclofenac / AUC Diclofenac quantified in plasma, on days 1 (without pineapple juice) and 11 (after pretreatment with pineapple juice);   (b) AUC 4-OH-Diclofenac/ AUC Diclofenac quantified in urine, on days 1 (without pineapple juice) and 11 (after pretreatment with pineapple juice)
15 Unknown  The Comparison Between the Therapeutic Affect of Intravitreal Diclophenac and Triamcinolone in Persistent Uveitic Cystoids Macular Edema
Conditions: Uveitis;   Cystoid Macular Edema
Interventions: Drug: Diclophenac;   Drug: Triamcinolone
Outcome Measure:
16 Unknown  Efficacy of Diclofenac BCG Irrigations
Condition: Bladder Cancer
Interventions: Drug: Abitren;   Drug: Placebo
Outcome Measures: Change in weekly COOP Questionnaire 1;   Change in weekly COOP Questionnaire 2;   Change in weekly COOP Questionnaire 3;   Change in weekly Bladder symptoms Questionnaire;   Change in weekly time schedule questionnaire
17 Unknown  Intravitreal Diclofenac Versus Avastin as Primary Treatment of Diffuse Diabetic Macular Edema
Condition: Diffuse Diabetic Macular Edema
Interventions: Drug: Bevacizumab;   Drug: Diclofenac
Outcome Measure:
18 Not yet recruiting Diclofenac add-on to Treatment as Usual for Suicidal Patients
Condition: Depression Suicidal
Interventions: Drug: sugar pill;   Drug: Diclofenac
Outcome Measures: Suicide Assessment Scale (differences in scores before and after treatment);   Montgomery Asberg Rating Scale (differences in scores before and after treatment);   Barratt Impulsiveness Scale (differences in scores before and after treatment);   Montgomery Asberg depression Ratin scale (changes in suicidality item before and after treatment);   Montgomery Asberg Rating Scale (changes in concentration item before and after treatment);   Comprehensive Psychopathological Rating Scale (changes in aggressive feelings item before and after treatment);   Comprehensive Psychopthological Rating Scale (changes in fatigue item before and after treatment)
19 Recruiting Post ERCP Pancreatitis Prevention in Average Risk Patients
Condition: Pancreatitis
Intervention: Procedure: Ceftazidime
Outcome Measure: Incidence of PEP in the group of patients receiving Ceftazidime versus incidence of PEP in the group of patients receiving Diclophenac potassium
20 Recruiting OASIS: Osteoarthritis Sensitivity Integration Study
Conditions: Osteoarthritis;   Chronic Pain
Intervention: Drug: duloxetine, Diclofenac
Outcome Measure: Pain