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SEPSIS and Simvastatin

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SEPSIS Symptoms and Causes

Sepsis is a serious illness. It happens when your body has an overwhelming immune response to a bacterial infection. The chemicals released into the blood to fight the infection trigger widespread inflammation. This leads to blood clots and leaky blood vessels. They cause poor blood flow, which deprives your body's organs of nutrients and oxygen. In severe cases, one or more organs fail. In the worst cases, blood pressure drops and the heart weakens, leading to septic shock.

Anyone can get Sepsis, but the risk is higher in

  • People with weakened immune systems
  • Infants and children
  • Adults 65 and older
  • People with chronic illnesses, such as diabetes, AIDS, cancer, and kidney or liver disease
  • People suffering from a severe burn or physical trauma

Common symptoms of Sepsis are fever, chills, rapid breathing and heart rate, rash, confusion, and disorientation. Doctors diagnose Sepsis using a blood test to see if the number of white blood cells is abnormal. They also do lab tests that check for signs of infection.

People with Sepsis are usually treated in hospital intensive care units. Doctors try to treat the infection, sustain the vital organs, and prevent a drop in blood pressure. Many patients receive oxygen and intravenous (IV) fluids. Other types of treatment, such as respirators or kidney dialysis, may be necessary. Sometimes, surgery is needed to clear up an infection.

NIH: National Institute of General Medical Sciences

Check out the latest treatments for SEPSIS

SEPSIS treatment research studies

Simvastatin clinical trials, surveys and public health registries


Find Drug Side Effect reports



Simvastatin Side Effects

Rhabdomyolysis (1122)
Myalgia (992)
Renal Failure Acute (459)
Blood Creatine Phosphokinase Increased (458)
Fatigue (445)
Pain In Extremity (403)
Muscular Weakness (399)
Asthenia (367)
Arthralgia (352)
Muscle Spasms (301)
Pain (282)
Dyspnoea (268)
Dizziness (261)
Nausea (236)
Diarrhoea (221)
Alanine Aminotransferase Increased (217)
Fall (217)
Gait Disturbance (195)
Headache (194)
Myositis (193)
Malaise (187)
Myopathy (180)
Back Pain (166)
Amnesia (163)
Vomiting (160)
Insomnia (157)
Depression (156)
Rash (154)
Aspartate Aminotransferase Increased (152)
Renal Failure (143)
Liver Function Test Abnormal (141)
Abdominal Pain (140)
Chest Pain (134)
Blood Creatinine Increased (133)
Confusional State (130)
Hypoaesthesia (126)
Paraesthesia (126)
Feeling Abnormal (123)
Memory Impairment (122)
Anxiety (117)
Myocardial Infarction (112)
Weight Decreased (111)
Cough (107)
Pruritus (107)
Condition Aggravated (106)
Cerebrovascular Accident (104)
Tendon Rupture (103)
Hepatic Enzyme Increased (101)
Abasia (98)
Mobility Decreased (98)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I been on simastatin 20gms for 4 yrs. I remember I did had a rash last Aug 09 and it was realy itch. After 2 wks of suffering. I finally made Appt. with my Dr.. They schelule me for the following week. The day I planed t

:(vvery dissy imsoniac light headness.................. =-O

A few months ago my doctor prescribed 40mg simvastatin to take one before bedtime ,and he never told me anything about the side efect of thid drug,I have started feeling some muscle pain and abdomnel paint that was later on after I started taking the

Blurred vision, like I was looking through water around the outside of my eyes, then very dizz, faint but not fainting--this has happened twice, I was shaky and weak after--it was frightening.....

Extreme muscle pain in legs, shoulders, neck and back. already had fibromyalgia and this was worse than any pain had previous to taking simvastatin. I was on it a yr. I had chonic insomnia, chest pain like pneumonia, so tired couldn't hardly move. co

Hair loss

Has anyone taking this medication after a year,expierenced headaches?

Have been on Zocor for almost 10 years with no problems but 6 months ago started getting rash on my left side which seems to be less annoying with good skin lotion. I also take some vitamin pills that have 1000% niacin(for building good HDL) and Niac

Hello All. I am a 39 yr old male. I contracted MRSA from a spot on my right little toe which had to be amputated. All was going well for the next month and then I turn very sick, running high fevers with chills, almost like I was getting the flu.

I am taking 40 mg of simvaststin and my hair is really falling out bad. it stated this after i've been on the drug for awhile. should i stop taking it to see will my hair stop coming out from the root?

Could this 'fluid' be secondary to an LRTI? Sepsis? or an allergic/anaphylactic reaction? ARDS? Why would a selective COX 2 inhibitor be the first choice for her? What ever happened to simple things like paracetamol? What did the autopsy say?

I had surgery with a terrible complication eleven months ago called sepsis. Since then I have right sided tremors, chronic right side pain, pain in my right shoulder, just to name a few complication. I wonder if I will ever be over the complications.

I have been in hospital for 5 days with sepsis and was treated with intravenus antibiotics.on my release i still have a bad cough, sore head and no energy. how long will this last?

I was rencently hospitalized with sepsis for 4 days. It was the result of UTI which is a constant plague in my life. Treatment with antibiotics and IV did the trick and my white blood count went down and blood pressure went from 40 to over 100 duri

My dad passed last week of sepsis with in 24 hour time frame on sunday he was laughing and joking around at at night felt like he had flu , slight throwing up and l00. temp during the night my mother said his fever spiked and she thought th

My father died of biliary sepsis in december what causes it?

MY FATHER PASSED AWAY FROM SEPSIS ON JUNE 22, 2010 AFTER BEING IN CVICU FOR 1 MONTH. WE STILL AREN'T SURE WHERE HE DEVELOPED THIS INFECTION FROM, POSSIBLY THE ABDOMEN. HE PASSED FROM SEPTIC SHOCK.

My mom developed Sepsis following hernia surgery. Nurse forgot to take out IV. She didnt realize it till shw got home. 10 days later she was admitt ed for kidney failure.

What is best filter to use in sepsis?

While taking Imuran be sure your Doctor keeps an eye on your WBC... Small infections could end up as Sepsis...

SEPSIS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.