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SINUSITIS and RECLAST

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SINUSITIS Symptoms and Causes

Sinusitis means your sinuses are inflamed. The cause can be an infection or another problem. Your sinuses are hollow air spaces within the bones surrounding the nose. They produce mucus, which drains into the nose. If your nose is swollen, this can block the sinuses and cause pain.

There are several types of Sinusitis, including

  • Acute, which lasts up to 4 weeks
  • Subacute, which lasts 4 to 12 weeks
  • Chronic, which lasts more than 12 weeks and can continue for months or even years
  • Recurrent, with several attacks within a year

Acute Sinusitis often starts as a cold, which then turns into a bacterial infection. Allergies, nasal problems, and certain diseases can also cause acute and chronic Sinusitis.

Symptoms of Sinusitis can include fever, weakness, fatigue, cough, and congestion. There may also be mucus drainage in the back of the throat, called postnasal drip. Your health care professional diagnoses Sinusitis based on your symptoms and an examination of your nose and face. You may also need imaging tests. Treatments include antibiotics, decongestants, and pain relievers. Using heat pads on the inflamed area, saline nasal sprays, and vaporizers can also help.

NIH: National Institute of Allergy and Infectious Diseases

Check out the latest treatments for SINUSITIS

SINUSITIS treatment research studies

RECLAST clinical trials, surveys and public health registries


Find Drug Side Effect reports



RECLAST Side Effects

Arthralgia (599)
Pain (418)
Myalgia (402)
Headache (341)
Bone Pain (334)
Pyrexia (332)
Influenza Like Illness (315)
Nausea (272)
Chills (241)
Asthenia (234)
Fatigue (233)
Back Pain (228)
Pain In Extremity (213)
Dizziness (181)
Dyspnoea (177)
Chest Pain (163)
Vomiting (163)
Malaise (141)
Gait Disturbance (136)
Diarrhoea (128)
Death (122)
Pain In Jaw (121)
Muscle Spasms (112)
Feeling Abnormal (101)
Abasia (99)
Musculoskeletal Pain (99)
Oedema Peripheral (98)
Blood Creatinine Increased (95)
Fall (89)
Joint Swelling (84)
Neck Pain (83)
Dehydration (79)
Confusional State (76)
Muscular Weakness (73)
Blood Pressure Increased (69)
Abdominal Pain (67)
Renal Failure Acute (67)
Musculoskeletal Stiffness (66)
Paraesthesia (66)
Hypoaesthesia (65)
Decreased Appetite (63)
Insomnia (60)
Erythema (59)
Eye Pain (58)
Chest Discomfort (57)
Atrial Fibrillation (56)
Activities Of Daily Living Impaired (55)
Hypocalcaemia (54)
Syncope (53)
Osteonecrosis (52)

➢ More


Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

I just had the infusion two days ago (1/19/10) and was surprised with the intensity of muscle pain the day after the treatment. My pain was localized to my rib cage, neck, shoulders and upper back. In addition I was very fatiqued...slept most of

"Association does not equal causation": posters seem to assume that any symptom occurring within a year of the Reclast infusion is caused by Reclast (just noticing that, and wondering whether the manufacturer needs to do a better jo

<span style='color: #808080;'>i was very unsure about reclast but the specialist was very pushie about me tring it,when i read up on it everything negative ( as far as reviews) my doc said don't go by reviews.aftre 2 mths i

Tell women not to take this drug. I for see huge lawsuits in the future. I may not live that long but it will happen! I was told to report to the hospital for my infusion. No one told me mu

<span style='color: #808080;'>si vous prenez le medrol 16 mg mangez des dattes et des bananes qui sont riches en potassium et n'oubliez pas de faire des analyses de temps en temps , une chute de potassium pourrait&ecirc;tre&nb

<strong></strong><span style='color: #808080;'>I had my first Reclast infusion last Thursday morning. I am a nurse so am on my feet a lot and at work Thursday evening I started having pain across the back of my

12 hours after Reclast IV, had fever, chills, pain in stomach, dizziness, headache - lasted 12 hours on and off - scary.

2 months after injection . I want to say I was extremely ill the day, about 10 hours afterwards , I got my Iv infusion of this medication . About 10 hours after the IV infusion I became very sick , Flu like symptoms , 103.6 temperture , thought

About 6 weeks after I got Reclast I got pains in my groin and hip. Is that a coincidence or is it possible to have these symptoms so long after the infusions. It is now 5 months and I now have pain in both hips, back and tingling in my feet and one

After my first (and last) experience with this drug, on January 5, 2011, I'm in pain. My back,my shoulder, my neck, my chest hurt. I'm taking pain killers to deal with the pain, but its not enough. Did someone had a better way ease the pain?

Does Rhinopront used in treating sinusitis? is it effective.

Elderly patient with IT and massive mastoid sinusitis being treated with vancomycin/cipro IV duo. Side effects???

I decided to treat it from the root and found out that a disfunctional adrenal gland or thyroid may cause the allergic reaction (allergic rhinitis and sinusitis). Docotors usually prescribe steroids and /or anti-histamines.. but really what they shou

I had a bad reaction to Bactrim in 1987-I still don't have my health back. Now I have asthma and sinusitis, chemical sensitivities and immune problems. Don't take this killer drug under ANY circumstances.

I had Rovamycine many times after dentist work, as I have mitral stenosis, (Valvotomy). Also I used it for my sinusitis, sore thoat (strep throat). I found especially good for my heart, as I cannot use penicillin at all (allergy)

I have been battling with some chronic sinusitis (Dr's still don't know if its bacterial or allergic) - so I was instructed to use Mucinex with Afrin at night. I took 2 small drops of Afrin in each nostirl, and 1 Mucinex D tablet and had a horrible r

I have been sick with allergies/asthma/sinusitis for over a week and when I took Mucinex DM I made sure to read the label carefully. My carton said to take 1 every 12 hours and no more than 2 in 24 hours. After taking the first pill it had no effect

I have sinusitis and I have lysomucil 600mg inthe house. Can i take this for my blocked sinuses, will it help? Thankyou

I started experiencing severe sinus headaches in the frontal sinus gland about 1 day after starting Restasis. I went to the doctor and they said it was sinusitis but none of the meds they gave me seemed to relieve the pain. My head is sore to the t

I started Lisinopril 40MG and Metoprolol 50MG almost two years ago. I have had chronic sinusitis for 30 years so when things starting getting bad I was not sure if it was the medication or my sinus problems because I could no longer take decongest

SINUSITIS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Sinusitis in Children and the Nasopharyngeal Microbiome
Condition: Sinusitis
Intervention:
Outcome Measures: Incidence of acute bacterial Sinusitis in children 49 to 84 months of age (which is the peak age incidence of Sinusitis) as a complication of an antecedent viral URI.;   Define relationships between the nasopharyngeal microbiome, viral illnesses, and progression to clinical Sinusitis.
2 Recruiting Efficacy of Azithromycin Prophylaxis in Preventing Recurrent Acute Sinusitis in Children
Condition: Sinusitis
Interventions: Drug: placebo;   Drug: azithromycin
Outcome Measure: frequence of acute Sinusitis during 12 mouths of study period
3 Not yet recruiting Pulmozyme in Cystic Fibrosis With Sinusitis
Conditions: Sinusitis;   Cystic Fibrosis
Interventions: Drug: Pulmozyme single use ampule;   Drug: placebo
Outcome Measure: 1. To assess changes in quality of life of patients with Cystic Fibrosis while on DNASE as compared to placebo.
4 Not yet recruiting Association of Periostin Levels and Chronic Sinusitis
Conditions: Sinusitis;   Nasal Polyps
Intervention: Other: Blood draw
Outcome Measure: Difference in circulating serum periostin levels pre and post sinus surgery
5 Recruiting Short (5 Days) Versus Long (14 Days) Duration of Antimicrobial Therapy for Acute Bacterial Sinusitis in Children
Condition: Sinusitis
Interventions: Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Placebo
Outcome Measure: Comparison of short course to long course antimicrobials.
6 Recruiting Genetic Factors in Chronic Sinusitis
Condition: Chronic Sinusitis
Intervention:
Outcome Measure: Association of genetic variation with CRS disease status
7 Recruiting Development and Validation of a NIRS-based Sinusitis Screening
Condition: Sinusitis
Intervention: Device: Optical imaging NIR
Outcome Measure: Optical imaging NIR tool to assess of Sinusitis
8 Recruiting Xylitol Versus Saline in Chronic Sinusitis
Condition: Chronic Sinusitis
Interventions: Drug: Xylitol;   Drug: Saline
Outcome Measures: SNOT-20;   antibiotic use
9 Unknown  The Clinical Efficacy of Topical Nasal Pomegranate Fruit Extract for Patients With Chronic RhinoSinusitis
Conditions: Rhinitis;   Sinusitis;   Nasal Polyps
Intervention:
Outcome Measure:
10 Recruiting Vitamin D for Chronic Sinusitis
Condition: Chronic Sinusitis
Interventions: Dietary Supplement: vitamin D placebo;   Dietary Supplement: Vitamin D
Outcome Measures: score on the Sinonasal Outcome Test-22 (SNOT-22);   Quality of life as measured by SF-36
11 Recruiting Effects of Endoscopic Sinus Surgery for Chronic Sinusitis on Asthma Control
Conditions: Asthma;   Chronic Sinusitis
Interventions: Procedure: Endoscopic Sinus Surgery;   Other: medical therapy
Outcome Measure: Asthma Control Score
12 Recruiting Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps
Condition: Chronic Sinusitis With or Without Nasal Polyps
Intervention: Drug: Fluticasone Propionate
Outcome Measure: Summary of Safety Evaluations
13 Recruiting Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps
Condition: Chronic Sinusitis With or Without Nasal Polyps
Intervention: Drug: Fluticasone Propionate
Outcome Measure: Summary of Safety Data
14 Recruiting An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis
Condition: Nasal Polyps
Interventions: Drug: dupilumab SAR231893 (REGN668);   Other: placebo;   Drug: mometasone furoate nasal spray
Outcome Measures: Change from baseline in endoscopic Nasal Polyp Score (NPS);   Change from baseline in NPS in sub-group of co-morbid asthma;   Change from baseline in patient reported symptoms of Sinusitis;   Change from baseline in nasal peak inspiratory flow;   Change from baseline in smell test;   Change from baseline in CT scan;   Time to first response in NPS
15 Unknown  Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis
Conditions: Chronic;   Sinusitis;   Polyposis
Intervention: Drug: pulmicort
Outcome Measures: olfaction;   Sinonasal health;   Olfaction
16 Recruiting Clinical Study to Improve Diagnosis and Treatment of Sinusitis
Condition: Chronic Sinusitis
Intervention:
Outcome Measure:
17 Recruiting Comparison of Balloon Sinuplasty In-Office Versus Medical Management for Recurrent Acute Sinusitis Patients (CABERNET)
Condition: Recurrent Acute RhinoSinusitis
Interventions: Device: balloon sinus dilation;   Other: medical therapy
Outcome Measures: Change in disease-specific patient-reported quality of life (QOL);   Change in disease-specific patient-reported quality of life;   Change in disease-specific and general health-related quality of life;   Change in disease-specific medication usage;   Missed days work/school and medical care visits due to Sinusitis;   Number of sinus infections;   Number of subjects electing procedure (cross-over);   Post-procedure return to normal activity (RTNA)
18 Recruiting Chronic RhinoSinusitis With or Without Nasal Polyps Steroid Study
Conditions: Chronic Sinusitis;   RhinoSinusitis;   Nasal Polyps
Intervention: Drug: Prednisone
Outcome Measure: Alterations of inflammatory cells, levels of key antibodies and cytokines, and expression of key epithelial genes
19 Unknown  Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic RhinoSinusitis
Condition: Chronic Sinusitis
Intervention:
Outcome Measures: Frequency of Sinusitis;   Complications of gentamicin nasal irrigation usage;   Frequency of antibiotic usage
20 Recruiting Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic RhinoSinusitis
Condition: Sinusitis
Interventions: Drug: Doxycycline;   Drug: Azithromycin;   Drug: Augmentin
Outcome Measures: Number of patients recommended for sinus surgery after 3 weeks of antibiotic therapy;   Number of patients recommended for sinus surgery after 6 weeks of antibiotic therapy;   Change in Quality of Life after 3 weeks of antibiotics;   Change in Quality of Life after 6 weeks of antibiotics;   Change in Nasal endoscopy scores after 3 weeks of antibiotics;   Change in Nasal Endoscopy Score following 6 weeks of antibiotics;   Change in CT Score after 3 weeks of antibiotics;   Change in CT Score after 6 weeks of antibiotics;   Number of patients with antibiotic side effects after a 3 week course of antibiotics;   Number of subjects with antibiotic side effects after a 6 week course of antibiotics