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SLEEP DISORDER and Levitra

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SLEEP DISORDER Symptoms and Causes

What is sleep?

Sleep is a complex biological process. While you are sleeping, you are unconscious, but your brain and body functions are still active. They are doing a number of important jobs that help you stay healthy and function at your best. So when you don't get enough quality sleep, it does more than just make you feel tired. It can affect your physical and mental health, thinking, and daily functioning.

What are sleep disorders?

Sleep disorders are conditions that disturb your normal sleep patterns. There are more than 80 different sleep disorders. Some major types include

  • Insomnia - being unable to fall asleep and stay asleep. This is the most common sleep disorder.
  • Sleep apnea - a breathing disorder in which you stop breathing for 10 seconds or more during sleep
  • Restless leg syndrome (RLS) - a tingling or prickly sensation in your legs, along with a powerful urge to move them
  • Hypersomnia - being unable to stay awake during the day. This includes narcolepsy, which causes extreme daytime sleepiness.
  • Circadian rhythm disorders - problems with the sleep-wake cycle. They make you unable to sleep and wake at the right times.
  • Parasomnia - acting in unusual ways while falling asleep, sleeping, or waking from sleep, such as walking, talking, or eating

Some people who feel tired during the day have a true sleep disorder. But for others, the real problem is not allowing enough time for sleep. It's important to get enough sleep every night. The amount of sleep you need depends on several factors, including your age, lifestyle, health, and whether you have been getting enough sleep recently. Most adults need about 7-8 hours each night.

What causes sleep disorders?

There are different causes for different sleep disorders, including

  • Other conditions, such as heart disease, lung disease, nerve disorders, and pain
  • Mental illnesses, including depression and anxiety
  • Medicines
  • Genetics

Sometimes the cause is not known.

There are also some factors that can contribute to sleep problems, including

  • Caffeine and alcohol
  • An irregular schedule, such as working the night shift
  • Aging. As people age, they often get less sleep or spend less time in the deep, restful stage of sleep. They are also more easily awakened.
What are the symptoms of sleep disorders?

The symptoms of sleep disorders depend on the specific disorder. Some signs that you may have a sleep disorder include that

  • You regularly take more than 30 minutes each night to fall asleep
  • You regularly wake up several times each night and then have trouble falling back to sleep, or you wake up too early in the morning
  • You often feel sleepy during the day, take frequent naps, or fall asleep at the wrong times during the day
  • Your bed partner says that when you sleep, you snore loudly, snort, gasp, make choking sounds, or stop breathing for short periods
  • You have creeping, tingling, or crawling feelings in your legs or arms that are relieved by moving or massaging them, especially in the evening and when trying to fall asleep
  • Your bed partner notices that your legs or arms jerk often during sleep
  • You have vivid, dreamlike experiences while falling asleep or dozing
  • You have episodes of sudden muscle weakness when you are angry or fearful, or when you laugh
  • You feel as though you cannot move when you first wake up
How are sleep disorders diagnosed?

To make a diagnosis, your health care provider will use your medical history, your sleep history, and a physical exam. You may also have a sleep study (polysomnogram). The most common types of sleep studies monitor and record data about your body during a full night of sleep. The data includes

  • Brain wave changes
  • Eye movements
  • Breathing rate
  • Blood pressure
  • Heart rate and electrical activity of the heart and other muscles

Other types of sleep studies may check how quickly you fall asleep during daytime naps or whether you are able to stay awake and alert during the day.

What are the treatments for sleep disorders?

Treatments for sleep disorders depend on which disorder you have. They may include

  • Good sleep habits and other lifestyle changes, such as a healthy diet and exercise
  • Cognitive behavioral therapy or relaxation techniques to reduce anxiety about getting enough sleep
  • CPAP (continuous positive airway pressure) machine for sleep apnea
  • Bright light therapy (in the morning)
  • Medicines, including sleeping pills. Usually, providers recommend that you use sleeping pills for a short period of time.
  • Natural products, such as melatonin. These products may help some people, but are generally for short-term use. Make sure to check with your health care provider before you take any of them.

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SLEEP DISORDER Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Safety and Clinical Effectiveness of 2 Lower Dose Combined PDE5i's vs. Single Maximal Dose PDE5i
Condition: Impotence
Interventions: Drug: Sildenafil, Vardenafil;   Drug: Sildenafil;   Drug: Vardenafil;   Drug: Sildenafil & Vardenafil
Outcome Measure: increase of 5 points or more in the IIEF erectile function domain
2 Unknown  A Study to Evaluate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction Caused by Spinal Cord Injury
Condition: Erectile Dysfunction
Interventions: Drug: Vardenafil;   Drug: Placebo
Outcome Measures: EF domain score of IIEF;   IIEF/SEP/GAQ
3 Not yet recruiting Vardenafil as add-on Therapy for Patients With Pulmonary Hypertension Treated With Inhaled Iloprost
Condition: Pulmonary Arterial Hypertension
Intervention: Drug: Levitra
Outcome Measures: Change in 6 minute walk or New York Heart Association functional class.;   Changes in Pulmonary artery pressure assessed (by echo), exercise test parameters, pro-NT BNP, quality of life. Clinical worsening during study, study drop-out and adverse events during the study.
4 Recruiting Effect of Testosterone on Endothelial Function and Microcirculation in Type 2 Diabetic Patients With Hypogonadism
Conditions: Type 2 Diabetes;   Hypogonadism
Intervention: Drug: Testosterone
Outcome Measures: Improvement in endothelial dependent and endothelial-independent vasodilatation;   Markers of endothelial function
5 Unknown  Long Acting Phosphodiesterase 5 Inhibitors as Add-on Therapy for Patients With Pulmonary Hypertension Treated With Prostanoids.
Condition: Pulmonary Arterial Hypertension
Interventions: Drug: Tadalafil;   Drug: Vardenafil
Outcome Measures: Six minute walking distance;   Level of pro-NT BNP;   Echo-derived parameters;   Cardiopulmonary exercise test
6 Recruiting PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
Condition: Anterior Ischemic Optic Neuropathy
Intervention: Drug: Diagnostic procedures
Outcome Measures: Confirmed diagnosis of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION);   Any additional safety information provided by the subject
7 Unknown  Treatment of Erectile Dysfunction in Hypogonadal Men With Testosterone Undecanoate
Conditions: Erectile Dysfunction;   Hypogonadotrophic Males
Intervention: Drug: Testosterone Undecanoate and/or PDE-5
Outcome Measures: Score higher than or equal to 21 of the erectile dysfunction domain of the IIEF, or response to treatment;   and/or an affirmative response to the GAQ will be considered for the analysis
8 Recruiting A Study of the Kinetics of Lymphoid Cells in Patients With Monoclonal B-cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL) and Healthy Volunteers
Condition: Monoclonal B-Cell Lymphocytosis
Intervention:
Outcome Measures: To estimate the cell proilferation rate of tumor cells in individuals with MBL, CLL/SLL, and MCL.;   Proliferation rate in tissue compared to blood, disappearance rate of labeled cells from the blood and tissue and the safety profile of heavy water in the study population/
9 Unknown  Can Hyperbaric Oxygen Improve Erectile Function Following Surgery for Prostate Cancer
Conditions: Impotence;   Prostatic Neoplasms
Interventions: Drug: Sildenafil therapy plus post-NSRRP HBO2T;   Drug: Sildenafil therapy plus sham post-NSRRP HBO2T
Outcome Measures: Erectile function domain of Internation Index of Erectile Function (IIEF);   clinical or biochemical recurrence of cancer