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SLEEP DISORDER and Seroquel

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SLEEP DISORDER Symptoms and Causes

What is sleep?

Sleep is a complex biological process. While you are sleeping, you are unconscious, but your brain and body functions are still active. They are doing a number of important jobs that help you stay healthy and function at your best. So when you don't get enough quality sleep, it does more than just make you feel tired. It can affect your physical and mental health, thinking, and daily functioning.

What are sleep disorders?

Sleep disorders are conditions that disturb your normal sleep patterns. There are more than 80 different sleep disorders. Some major types include

  • Insomnia - being unable to fall asleep and stay asleep. This is the most common sleep disorder.
  • Sleep apnea - a breathing disorder in which you stop breathing for 10 seconds or more during sleep
  • Restless leg syndrome (RLS) - a tingling or prickly sensation in your legs, along with a powerful urge to move them
  • Hypersomnia - being unable to stay awake during the day. This includes narcolepsy, which causes extreme daytime sleepiness.
  • Circadian rhythm disorders - problems with the sleep-wake cycle. They make you unable to sleep and wake at the right times.
  • Parasomnia - acting in unusual ways while falling asleep, sleeping, or waking from sleep, such as walking, talking, or eating

Some people who feel tired during the day have a true sleep disorder. But for others, the real problem is not allowing enough time for sleep. It's important to get enough sleep every night. The amount of sleep you need depends on several factors, including your age, lifestyle, health, and whether you have been getting enough sleep recently. Most adults need about 7-8 hours each night.

What causes sleep disorders?

There are different causes for different sleep disorders, including

  • Other conditions, such as heart disease, lung disease, nerve disorders, and pain
  • Mental illnesses, including depression and anxiety
  • Medicines
  • Genetics

Sometimes the cause is not known.

There are also some factors that can contribute to sleep problems, including

  • Caffeine and alcohol
  • An irregular schedule, such as working the night shift
  • Aging. As people age, they often get less sleep or spend less time in the deep, restful stage of sleep. They are also more easily awakened.
What are the symptoms of sleep disorders?

The symptoms of sleep disorders depend on the specific disorder. Some signs that you may have a sleep disorder include that

  • You regularly take more than 30 minutes each night to fall asleep
  • You regularly wake up several times each night and then have trouble falling back to sleep, or you wake up too early in the morning
  • You often feel sleepy during the day, take frequent naps, or fall asleep at the wrong times during the day
  • Your bed partner says that when you sleep, you snore loudly, snort, gasp, make choking sounds, or stop breathing for short periods
  • You have creeping, tingling, or crawling feelings in your legs or arms that are relieved by moving or massaging them, especially in the evening and when trying to fall asleep
  • Your bed partner notices that your legs or arms jerk often during sleep
  • You have vivid, dreamlike experiences while falling asleep or dozing
  • You have episodes of sudden muscle weakness when you are angry or fearful, or when you laugh
  • You feel as though you cannot move when you first wake up
How are sleep disorders diagnosed?

To make a diagnosis, your health care provider will use your medical history, your sleep history, and a physical exam. You may also have a sleep study (polysomnogram). The most common types of sleep studies monitor and record data about your body during a full night of sleep. The data includes

  • Brain wave changes
  • Eye movements
  • Breathing rate
  • Blood pressure
  • Heart rate and electrical activity of the heart and other muscles

Other types of sleep studies may check how quickly you fall asleep during daytime naps or whether you are able to stay awake and alert during the day.

What are the treatments for sleep disorders?

Treatments for sleep disorders depend on which disorder you have. They may include

  • Good sleep habits and other lifestyle changes, such as a healthy diet and exercise
  • Cognitive behavioral therapy or relaxation techniques to reduce anxiety about getting enough sleep
  • CPAP (continuous positive airway pressure) machine for sleep apnea
  • Bright light therapy (in the morning)
  • Medicines, including sleeping pills. Usually, providers recommend that you use sleeping pills for a short period of time.
  • Natural products, such as melatonin. These products may help some people, but are generally for short-term use. Make sure to check with your health care provider before you take any of them.

Check out the latest treatments for SLEEP DISORDER

SLEEP DISORDER treatment research studies

Seroquel clinical trials, surveys and public health registries


Find Drug Side Effect reports



Seroquel Side Effects

Diabetes Mellitus (6103)
Type 2 Diabetes Mellitus (3575)
Insomnia (2241)
Pancreatitis (1939)
Blood Cholesterol Increased (1705)
Weight Increased (1696)
Obesity (1197)
Diabetes Mellitus Inadequate Control (1084)
Diabetic Ketoacidosis (1083)
Depression (1046)
Hyperglycaemia (1037)
Diabetic Neuropathy (1010)
Somnolence (997)
Anxiety (972)
Malaise (971)
Off Label Use (948)
Feeling Abnormal (830)
Blood Triglycerides Increased (806)
Suicidal Ideation (805)
Diabetic Coma (803)
Convulsion (757)
Death (753)
Neuropathy Peripheral (744)
Tardive Dyskinesia (696)
Dizziness (683)
Type 1 Diabetes Mellitus (667)
Hyperlipidaemia (662)
Chest Pain (641)
Hypertension (632)
Fall (631)
Fatigue (612)
Headache (611)
Overdose (594)
Suicide Attempt (564)
Back Pain (547)
Bipolar Disorder (519)
Nausea (492)
Agitation (488)
Tremor (449)
Dyspnoea (437)
Confusional State (432)
Loss Of Consciousness (403)
Vomiting (395)
Mental Disorder (383)
Blood Glucose Increased (382)
Abdominal Pain (378)
Cardiac Disorder (373)
Cerebrovascular Accident (370)
Asthenia (368)
Aggression (359)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
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Celexa (1342)
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Cipro (8580)
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Medrol (650)
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Prednisone (5926)
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Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
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Tramadol (5054)
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Viagra (5394)
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Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

After taking 300 mgm a day of seroquel, I gained 30 lbs over a period of 3 months with all the symptoms of metabolic syndrome. Now I am unable to lose that weight even though I no longer take the medicati9on

After taking Seroquel for about two weeks, I came down with quite serious laryngitis. I've had it for about a week and it is not getting any better. I don't have a cold or sore throat and can't think of any other reason for this. Could this be cau

Check out my med list; kind like a handbook isn't it?

Doing range of motion exercises on the neck with the head is an excellent way of treating cronic insomonia. >:o O:-)

I also had to increase the weight for my pendulum exercises to make easier to adjust my shoulder. :)

I also had to raise my arms up and down behind my head in order to adjust the top of my neck.

I am having the same experience. I also had been taking Seroquel for about 2 weeks when I began to lose my voice. I am researching today because my laryngitis is practically 100% today.

I Believe Seroquel killed my husband. He tried to get help with depression and suiside and seroquel made him worse. I totally believe this awful drug killed him and he was only 45. I miss him terribly and hope I can help to keep suiside patients off

I had such severe side effects I thought I was going insane. My husband even got out the video camera to show me how bad it was. I rocked and rocked back and forth, my entire body shook involuntarily, I paced, I didn't sleep,I couldn't rest or relax

I have been taking seroquel and zyban. i have two children, and trying for another. When i gave birth to my children i was on other medication. Since on this combination of seroquel and zyban i cannot seem to ovulate.

I have been put on Molipaxin 3 weeks ago, I have dry mouth, hair loss and my panic attacks were showing no signs of improvement. Dr increased it to 100mg and put me onto Lamictin. I am not bi polar nor epileptic. My disorder ist algora phoebia. I a

muscle cramping when in a dead sleep

Does anyone else have insomnia problems, with this drug, was fine before taking it, but now having major trouble getting to sleep and staying asleep.

Had complete hysterectomy in 1999 and developed cystis acne. Was 34 at the time. Prescribed accutane for 9 months. Worked great with the usual side effects-dry lips. Now 11 years later, I am suffering from a severe anxiety disorder with body dimorph

Had patch on for approximate 6 hrs went to bed become very unsettled unable to sleep, rapid heart beat. Ended up removing it as l could hear my heart beat loud & scary. I gave it some time before l tried the next patch - 4 days later l trie

I am taking 2 asacol three times a day and is very difficult sleep and my mouth is dry all the time.

i have couph then i sleep very well but iam ask about the diseffect of this medicine

I took pataday for the first time around 10pm, I was instructed by my optometrist to take 1 drop in each eye every 24 hours, its now 530am, I think this stuff had made it so i cannot sleep! I'm super tired but I just cannot sleep! Thanks pataday...

My symptoms were tired, weak, unable to sleep. Was prescribed half of a 15 MG Mirtazapine nightly to help me sleep. Has this drug been successful used as a sleeping aid?

<b>Describe Your Metaxalone Experience Here:</b> I took it for the firt night last night hoping that it would help my shoulder and knee pains and help me sleep and it had the opposite effect. I feel asleep fast but 2 hour

SLEEP DISORDER Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Pharmacokinetic Study Comparing Topical, Rectal, and Oral Quetiapine
Conditions: Dementia;   Delirium
Interventions: Drug: Quetiapine 25 mg gel applied topically;   Drug: Quetiapine 25 mg tablet by mouth;   Drug: Quetiapine 25 mg rectal suppository
Outcome Measures: Serum quetiapine levels after topical application (Visit 1);   Serum quetiapine levels after oral administration (Visit 2);   Serum quetiapine levels after rectal administration (Visit 3)
2 Unknown  A Study to Evaluate the Efficacy and Safety of Flexible Dose of Quetiapine Fumarate (Seroquel) Switching From Other Drugs in the Treatment of Acute Manic Patients With Bipolar Disorder
Condition: Bipolar Disorder
Intervention: Drug: quetiapine fumarate tablet (Seroquel)
Outcome Measures: The primary efficacy variable for this study is the YMRS total score change from baseline to Day 28 (LOCF).;   To evaluate the effectiveness of quetiapine fumarate;   To evaluate the relationship between the serum brain-derived neurotrophic factor and quetiapine fumarate;   To evaluate the safety and tolerability of quetiapine fumarate
3 Unknown  Effects of 'Seroquel-XR' on the Improvement of Neurocognitive Function in People At-risk Mental States(ARMS)
Conditions: Abnormal Mental State;   Schizophrenia
Intervention: Drug: Quetiapine(Seroquel-XR) 50~800mg a day
Outcome Measures: California Verbal Learning Test;   verbal & spatial 2-back test, Digit Span, 3-7 CPT, WCST, Rey-CFT, TMT A & B, COWAT, SOPS, PANSS, SAS, PAS, AIHQ, BIS
4 Unknown  Efficacy and Safety of Utapine vs. Seroquel in Patients With Bipolar Mania
Conditions: Bipolar, Mania;   Utapine;   Seroquel
Interventions: Drug: Utapine;   Drug: Seroquel
Outcome Measure:
5 Recruiting The Effect of Quetiapine XR in Depressive Patients Showing Aberrant N100 Amplitude Slope
Condition: Major Depressive Disorder
Interventions: Drug: SSRI monotherapy;   Drug: Seroquel XR adjunctive
Outcome Measures: Change from baseline in HDRS scale;   Change from baseline in CGI, BDI, and YMRS scales
6 Unknown  Pilot Study to Evaluate the Efficacy and Safety of Quetiapine Fumarate Instant-Release (Seroquel IR) in Controlling Agitation and Aggressive Symptoms in the Acute Treatment of Patients With Schizophrenia
Condition: Acute Schizophrenia
Interventions: Drug: Quetiapine fumarate;   Drug: Haloperidol
Outcome Measures: The primary objective of this study is to evaluate the efficacy of quetiapine fumarate in improving agitation and aggression symptoms for the schizophrenic patients;   The response rate of quetiapine in improving agitation and aggression symptoms - the efficacy of quetiapine - the safety and tolerability of quetiapine - differences between quetiapine and haloperidol
7 Unknown  Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry
Conditions: Schizophrenia;   Psychosis
Intervention: Drug: Quetiapine XR
Outcome Measures: The primary efficacy variable is the change in aggression between admission and day 8 of treatment with Quetiapine XR as measured by the OAS.;   Measuring psychotic symptomatology change from baseline in BPRS-Total Score in aggressive, psychotic patients managed with Quetiapine XR;   Measuring the incidence of adverse events (including Extrapyramidal symptoms) by the change from baseline in SAS and BAS and subjective reports;   Measuring the incidence of concomitant benzodiazepine and other permitted medication use
8 Unknown  Trial of Quetiapine in Anorexia Nervosa
Condition: Anorexia Nervosa
Intervention: Drug: Quetiapine
Outcome Measures: Primarily we will seek to show that Quetiapine is superior to placebo in terms of reducing core eating disorder symptoms on the Yale-Brown-Cornell Eating Disorder Scale (YBC-EDS) and the Eating Disorders Inventory-2.;   We seek to show that Quetiapine is superior to placebo in reducing anxiety, depression, obsessionality, or weight gain in patients with AN. We also will seek to show that Quetiapine is superior to placebo at reducing positive and negative symptoms.
9 Recruiting Quetiapine Pharmacotherapy for Cannabis Dependence
Condition: Cannabis Dependence
Interventions: Drug: Quetiapine;   Drug: Placebo
Outcome Measures: Marijuana Use;   Marijuana Abstinence;   Urine toxicology;   Marijuana withdrawal symptoms;   Marijuana craving;   Sleep disturbance
10 Unknown  Brain Derived Neurotrophic Factor as a Predictor of Response to Treatment in Bipolar Depression and Mania: 16-weeks Follow-up With Quetiapine XR
Condition: BIPOLAR DISORDER
Intervention: Drug: quetiapine
Outcome Measures: Efficacy of quetiapine as a treatment for acute mania and depression, and of as a manutence treatment.;   Assess the pharmacodynamics of quetiapine by neurotrophins in blood samples.
11 Recruiting Gao Bipolar Spectrum Lithium/Quetiapine Study
Condition: Bipolar Disorder
Interventions: Drug: Lithium;   Drug: Quetiapine
Outcome Measures: Time to study discontinuation;   Lithium vs. Quetiapine effects on general cardiovascular disease risk and role effects on general cardiovascular disease risk and role impairment
12 Not yet recruiting Safety and Tolerability of Quetiapine in Multiple Sclerosis
Condition: Multiple Sclerosis
Intervention: Drug: Extended-release quetiapine fumarate
Outcome Measures: Dose-limiting toxicity;   Adverse events
13 Recruiting Post-Traumatic Stress Disorder (PTSD) and Seroquel
Condition: Post-Traumatic Stress Disorder
Intervention: Drug: Seroquel
Outcome Measures: The primary outcome will be the change from baseline in PTSD symptomatology at the week 8 timepoint.;   The secondary outcome will be the change from baseline in PTSD symptomatology at the Week 8 timepoint.
14 Recruiting European Drug Utilization Study
Condition: Major Depressive Disorder (MDD)
Intervention:
Outcome Measures: Patient age (mean and range);   Patient gender (%);   Diagnosis for which Seroquel XR was prescribed (% of Major Depressive Disorder- MDD);   Patients hospitalized for any psychiatric condition (n, %);   Daily dose of Seroquel XR (mode and range);   Patient referral pathway (%);   Participating psychiatrist practice setting (%);   Percent of patients experiencing psychotic symptoms at initiation of Seroquel XR (n, %)
15 Unknown  Effects of Seroquel XR on Sleep Architecture in Patients With Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Quetiapine Fumarate Extended Release;   Other: healthy control
Outcome Measures: change from baseline Pittsburgh Quality Index total scores at 4 weeks;   change from baseline Pittsburgh Quality Index total scores at 2 weeks;   change from baseline Pittsburgh Quality Index total scores at 4 days;   change from baseline in sleep architecture measured using polysomnography at 4 weeks;   number of participants with adverse events
16 Recruiting Efficacy of Quetiapine for Pediatric Delirium
Condition: Delirium
Interventions: Drug: quetiapine;   Other: Placebo
Outcome Measures: Time to first resolution of delirium;   Total ICU days with delirium
17 Unknown  Heart Rate Changes in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine
Conditions: Schizophrenia;   Bipolar
Intervention: Drug: Aripiprazole; Quetiapine
Outcome Measure:
18 Recruiting Trial Comparing Haloperidol, Quetiapine and Placebo in the Pharmacological Treatment of Delirium
Condition: Delirium
Interventions: Drug: Quetiapine;   Drug: Haloperidol;   Drug: Placebo
Outcome Measures: Time to first resolution of delirium;   Days in delirium during the study;   Duration of delirium;   Severity of delirium (highest Nu-DESC score, mean episode Nu-DESC score);   ICU and hospital mortality;   ICU and hospital length of stay;   Length of mechanical ventilation;   Time spent deeply sedated (RASS <3);   Episodes of subject-initiated device removal;   Use of haloperidol therapy (including total dose in haloperidol equivalents during the study, number of doses, number of days of therapy, use of rescue IV haloperidol);   Average daily and maximum total antipsychotic drug dose in haloperidol equivalents;   Duration of study drug administration;   Use of benzodiazepines;   Use of opioids;   QTc prolongation;   Extrapyramidal symptoms;   Neuroleptic malignant syndrome
19 Recruiting Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania
Condition: Bipolar Disorder
Interventions: Drug: Lithium;   Drug: Valproate;   Drug: Oxcarbazepine;   Drug: Quetiapine;   Drug: Olanzapine;   Drug: Ziprasidone
Outcome Measures: Change from baseline in Young Mania Rating Scale at 2 weeks and 6 weeks;   rate of dropout (treatment discontinuation);   Clinical Global Impressions (CGI) Scale;   Brief Psychiatric Rating Scale;   Global Assessment Scale;   Treatment Emergent Symptom Scale;   Hamilton Anxiety Rating Scale;   Hamilton Depression Rating Scale
20 Unknown  Quetiapine for the Treatment of Insomnia in Alzheimer's Disease
Conditions: Alzheimer's Disease;   Insomnia
Intervention: Drug: quetiapine
Outcome Measures: The primary objective is to determine whether quetiapine can increase total sleep time and reduce time awake in patients with AD and sleep disturbance.;   Dose-response relationship of quetiapine and sleep in AD patients?;   Are there sleep architecture changes from quetiapine?;   Do the primary sleep variables change relative to placebo at any weekly time or dose point?;   Are caregivers, blind to treatment status, able to detect changes in sleep quality in the patients for quetiapine relative to placebo?;   Does quetiapine used at single bedtime dosing for potential nighttime soporific effect have a measurable impact on neuropsychiatric symptoms other than insomnia?