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THROMBOCYTOPENIA and Loratadine

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THROMBOCYTOPENIA Symptoms and Causes

Platelets, also known as thrombocytes, are small pieces of blood cells. They form in your bone marrow, a sponge-like tissue in your bones. Platelets play a major role in blood clotting. Normally, when one of your blood vessels is injured, you start to bleed. Your platelets will clot (clump together) to plug the hole in the blood vessel and stop the bleeding. You can have different problems with your platelets:

  • If your blood has a low number of platelets, it is called Thrombocytopenia. This can put you at risk for mild to serious bleeding. The bleeding could be external or internal. There can be various causes. If the problem is mild, you may not need treatment. For more serious cases, you may need medicines or blood or platelet transfusions.
  • If your blood has too many platelets, you may have a higher risk of blood clots.
    • When the cause is not known, this is called thrombocythemia. It is rare. You may not need treatment if there are no signs or symptoms. In other cases, people who have it may need treatment with medicines or procedures.
    • If another disease or condition is causing the high platelet count, it is thrombocytosis. The treatment and outlook for thrombocytosis depends on what is causing it.
  • Another possible problem is that your platelets do not work as they should. For example, in von Willebrand Disease, your platelets cannot stick together or cannot attach to blood vessel walls. This can cause excessive bleeding. There are different types of in von Willebrand Disease; treatment depends on which type you have.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for THROMBOCYTOPENIA

THROMBOCYTOPENIA treatment research studies

Loratadine clinical trials, surveys and public health registries


Find Drug Side Effect reports



Loratadine Side Effects

Dizziness (40)
Accidental Overdose (37)
Convulsion (37)
Dyspnoea (34)
Somnolence (31)
Headache (28)
Malaise (23)
Nausea (23)
Vomiting (23)
Hypersensitivity (23)
Urticaria (21)
Pain (21)
Pruritus (20)
Loss Of Consciousness (20)
Insomnia (19)
Death (19)
Syncope (19)
Palpitations (19)
Swelling Face (17)
Anxiety (17)
Blood Pressure Increased (16)
Abdominal Pain Upper (15)
Completed Suicide (15)
Rash (14)
Overdose (14)
Depression (14)
Asthenia (13)
Burning Sensation (13)
Fall (13)
Pyrexia (13)
Cholestasis (12)
Cardiac Arrest (12)
Condition Aggravated (12)
Diarrhoea (12)
Vision Blurred (12)
Confusional State (12)
Cough (12)
Abortion Spontaneous (11)
Cerebrovascular Accident (11)
Torsade De Pointes (11)
Feeling Abnormal (11)
Heart Rate Increased (11)
Muscle Spasms (10)
Ventricular Tachycardia (10)
Hyperhidrosis (10)
Agitation (9)
Angioedema (9)
Autoimmune Hepatitis (9)
Chest Pain (9)
Arrhythmia (9)

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Recent Reviews

one 10 mg pill cuased presure in thechest bad muslespasms in the back think past doses has sent me skizzo

Alopecia areata........ anyone else?

Can my one year old take loratadine

Can this medicine cause you to have a very fast heart rate?

Can you take tylenol right after taking a loratadine?

How long should a child of 5 years of age be on Loratadine (liquid form) and will this effect her alertness in school?

I was taking the loratadine 24 hr for about 4 months and past 3 months kept losing a lot of hair. Found bald spot few days ago and doc says alopecia areata. I saw a few postings on the internet of a correlation and wanted to know it anyone else has

Is 30mg too much in 24 hours?? is medical advice needed

My son experienced nightmares, several night wakenings, disorientation, restlessness, night sweats and a few days after stopping the medication had shortness of breath after exercising (with no previous asthmatic experiences)

Can amitriptyline can cause thrombocytopenia ?

Had Fluzone HD Oct.13, 2010, and on Nov. 4, 2010, platelet count was down to 64. Diagnosed with thrombocytopenia purpura Jan. 2011. Have done rounds of steroids and Rituxin and have had roller coaster platelet counts til present with latest count 60.

I have been on Risedronate since 2008 because I have osteoporosis and now I am diagnosed with Immuno thrombocytopeniaI am 60 years old

Patient received clomiphene for 5 days 2 months ago and developed severe anemia, thrombocytopenia with hypocellular marrow.

Sorry, that was ITP or, idiopathic thrombocytopenia purpura...

Thrombocytopenia

THROMBOCYTOPENIA Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Evaluation of Loratadine for Prevention of Pegfilgrastim-Induced Pain
Condition: Pegfilgrastim-induced Back and Leg Pain
Interventions: Drug: Loratadine;   Drug: placebo
Outcome Measures: Prevention of pegfilgrastim-induced back and leg pain by administration of the antihistamine Loratadine;   Identification of adverse events when Loratadine is given to prevent pegfilgrastim-induced back and leg pain;   Incidence of pegfilgrastim-induced back and leg pain
2 Recruiting NOLAN: Naproxen or Loratadine and Neulasta
Condition: Bone Pain in Stage I - III Breast Cancer
Interventions: Drug: Naproxen;   Drug: Loratadine
Outcome Measures: Bone pain (all grade) in cycle 1;   Bone pain (all grade) by cycle (2-4) and across cycles;   Severe (grade 3/4) bone pain by cycle and across cycles;   Subject reported bone pain;   Maximum Subject Reported bone pain;   Area under the Curve for subject-reported bone pain;   Adverse Event and Serious Adverse Events;   Severity of Adverse Events
3 Recruiting Long-Term Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)
Conditions: Rhinitis, Allergic, Perennial;   Rhinitis, Allergic, Nonseasonal
Interventions: Biological: MK-8237 tablets;   Biological: Placebo tablets;   Drug: Rescue Medication: Self-Injectable Epinephrine;   Drug: Rescue Medication: Loratadine tablets;   Drug: Rescue Medication: Olopatadine ophthalmic drops;   Drug: Rescue Medication: Mometasone furoate nasal spray
Outcome Measures: Average Total Combined Rhinitis Score (TCRS);   Number of Participants Who Experience At Least One Adverse Event;   Number of Participants Who Discontinue Study Drug Due to an Adverse Event;   Average Rhinitis Daily Symptom Score (Rhinitis DSS);   Average Total Combined Rhinoconjunctivitis Score (TCS);   Average Rhinitis Daily Medication Score (Rhinitis DMS);   Average Allergic Rhinitis/Rhinoconjunctivitis Symptoms Assessed by Visual Analogue Scale (VAS)
4 Unknown  Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint Replacement
Condition: Arthroplasty, Replacement, Knee
Interventions: Drug: Depodur;   Procedure: sciatic nerve block
Outcome Measures: Postoperative Pain;   Time Required for Placement of Block;   Time to first use of rescue analgesia and PCA;   Total opioid consumption;   Degree of knee flexion (Range of motion);   Day of first ambulation;   Number of days required to achieve a 110° knee flexion;   Number of days of hospitalization;   Need for manipulation of knee joint under general anesthesia;   Secondary effects: nausea and vomiting, pruritus, supplemental oxygen, urinary catheterization;   Satisfaction score