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TINNITUS and Cyclobenzaprine

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TINNITUS Symptoms and Causes

Tinnitus is often described as a ringing in the ears. It also can sound like roaring, clicking, hissing, or buzzing. It may be soft or loud, high pitched or low pitched. You might hear it in either one or both ears.

Millions of Americans have Tinnitus. People with severe Tinnitus may have trouble hearing, working or even sleeping.

Causes of Tinnitus include

  • Hearing loss in older people
  • Exposure to loud noises
  • Ear and sinus infections
  • Heart or blood vessel problems
  • Meniere's disease
  • Brain tumors
  • Hormonal changes in women
  • Thyroid problems
  • Certain medicines

Treatment depends on the cause. Treatments may include hearing aids, sound-masking devices, medicines, and ways to learn how to cope with the noise.

NIH: National Institute on Deafness and Other Communication Disorders

Check out the latest treatments for TINNITUS

TINNITUS treatment research studies

Cyclobenzaprine clinical trials, surveys and public health registries


Find Drug Side Effect reports



Cyclobenzaprine Side Effects

Completed Suicide (160)
Toxicity To Various Agents (127)
Cardiac Arrest (64)
Respiratory Arrest (59)
Overdose (36)
Pain (28)
Cardio-respiratory Arrest (24)
Dizziness (24)
Confusional State (23)
Death (21)
Exposure Via Ingestion (20)
Nausea (18)
Fall (16)
Depression (15)
Convulsion (15)
Constipation (15)
Anxiety (14)
Hallucination (14)
Hypotension (14)
Headache (14)
Vomiting (13)
Fatigue (13)
Dry Mouth (12)
Chest Pain (12)
Deep Vein Thrombosis (12)
Dyspnoea (12)
Loss Of Consciousness (12)
Pulmonary Embolism (12)
Asthenia (11)
Heart Rate Increased (11)
Insomnia (11)
Somnolence (11)
Myoclonus (11)
Delirium (10)
Aspartate Aminotransferase Increased (10)
Coma (10)
Diarrhoea (10)
Intentional Overdose (10)
Hypoaesthesia (10)
Back Pain (9)
Alanine Aminotransferase Increased (9)
Depressed Level Of Consciousness (9)
Gait Disturbance (9)
Tachycardia (9)
Serotonin Syndrome (9)
Hepatic Function Abnormal (8)
Injury (8)
Tremor (8)
Psychotic Disorder (8)
Mental Status Changes (8)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
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Cipro (8580)
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Crestor (18839)
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Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
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Neurontin (6501)
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Prednisone (5926)
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Prozac (1954)
Seroquel (27216)
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Synthroid (4452)
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Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

A constant hissing in both ears, that makes me not hear well and intolerance of some noises also I have a hard time being still in my thoughts...kind of an a.d.d. effect

A constant sound much like the night air sounds of rural Florida woods with crickets, cicadas, frogs and such with their symphony of sound all night long. I have this sound full time and have been taking 2 to 3 Vicoprofen a day for three years. I am

Confusion, ringing of ears, dry (stinging) eyes, nightmares, depression associated with hyper-sensitivity/over-reaction in social events.

Hi, I'm 21 years old, recently released from the hospital for possible brain infection (took a variety of antibiotics and anti-virals). I have possible diabetes and I recently developed tinnitus I think, and the possible causes for it is my prolonged

I have a rumbling , thundering , feeling of pressure in my left ear and it comes n goes ? my right ear has a satbbing pain in it ???????? runny noswe , cough n dry eyes????????? any answers?

Im 16 yrs old and i have a bad lower back and neck so i take cylobenzapr and one time i fell asleep and awoke and was talking but not making no sense

Also having a problem with tinnitus ... and I am on Pravistatin 10mg, along with extreme muscle pain and tiredness. I have quit taking this medication.

Did your tinnitus go away after stopping allpurinol?

Does Amtriptyline help tinnitus. I'm taking it at a low dose for jaw problems and fibromyalgia. the 25 mg dose seems to make my tinnitus worse but my pain better. I don't know what to do?

Extreme tinnitus after 1.5 days of use.

Female, 55. Have taken Aprovel 75 mg for three months. Have experienced confusion and memory problems, itchy skin and tinnitus. General feeling of anxiety and sleepiness.

Have been on Welchol (powder mix) for a month. Bottoms of my feet have become sore, getting rashes on face and experiencing tinnitus now as well. I also noticed that my blood sugars have shot up from 105 (normal) to 195.

Have developed tinnitus with allopurinol (or gabapentin). Up dose of allopurinol to 600mg daily in October 2010, and developed tinnitus in Dec 2010. Planning to stop then re-challenge.

Headaches, tinnitus, ichy rash, twiching muscles, insomnia, I would like to know if these symtoms will go away. I used this drug for about six years & I have been off the drug now for about six weeks.

Hi, I'm 21 years old, recently released from the hospital for possible brain infection (took a variety of antibiotics and anti-virals). I have possible diabetes and I recently developed tinnitus I think, and the possible causes for it is my prolonged

I also I have problem with my ear After taking Levoxyl I increased tinnitus. The sodium Levoxyl is what I think it does increase it. If you know if this is true, please let me know. Thanks

TINNITUS Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Inhibitor Masking Device & SCN9 Gene Expression
Condition: Tinnitus
Intervention: Device: The Inhibitor™ Tinnitus Masking Device
Outcome Measures: To evaluate the effectiveness of the Inhibitor™ Tinnitus Masking Device;   Genetic Sample to look for particular genetic expression.
2 Recruiting Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)
Condition: Tinnitus
Interventions: Procedure: Telephone Tinnitus Education;   Procedure: Wait List Control
Outcome Measure: Tinnitus Handicap Inventory
3 Recruiting Tinnitus Retraining Therapy Trial
Condition: Subjective Tinnitus
Interventions: Device: Conventional sound generator (SG);   Device: Placebo sound generator (placebo SG);   Behavioral: Standard of Care (SC);   Behavioral: Directive Counseling (DC)
Outcome Measures: Change in score on the Tinnitus Questionnaire (TQ);   Change in TQ sub-scale scores;   Change in Tinnitus Handicap Inventory (THI) score;   Change in Tinnitus Functional Index (TFI) score;   Change in TRT Interview Visual Analogue scales;   Change in Digit Symbol Substitution Test (DSST);   Change in psychoacoustic variables;   Hearing Handicap Inventory (HHI)
4 Recruiting rTMS for the Treatment of Chronic Tinnitus: Optimization by Simulation of the Cortical Tinnitus Network
Condition: Chronic Tinnitus
Interventions: Device: rTMS intervention 1;   Device: rTMS intervention 2
Outcome Measures: Number of treatment responders (TQ reduction ≥5, contrast baseline versus day 12);   Change of Tinnitus severity as measured by the Tinnitus Questionnaire of Goebel&Hiller (contrast baseline versus day 12);   Change of depressive symptoms as measured by the Major Depression Inventory (MDI);   Change in quality of life as measured by the WHOQoL;   Change in hyperacusis as measured by the German questionnaire "Geräuschüberempfindlichkeitsfragebogen";   Number of treatment responders (TQ reduction ≥5, contrast Baseline versus day 90);   Change of Tinnitus severity as measured by the Tinnitus Handicap Inventory (THI) and Tinnitus Severity Scale;   Number of treatment responders (TQ reduction ≥5, contrast Baseline versus day 180);   Change of Tinnitus severity as measured by the Tinnitus Questionaire of Goebel&Hiller
5 Recruiting Effect of rTMS on Resting State Brain Activity in Tinnitus
Condition: Tinnitus
Interventions: Device: Repetitive Transcranial Magnetic Stimulation (rTMS) - ACTIVE;   Device: Repetitive Transcranial Magnetic Stimulation (rTMS) - SHAM
Outcome Measures: Change in Tinnitus perception, as measured over time using a subjective visual analog rating scale;   Change in Beck's Depression Inventory (BDI);   Change in Tinnitus Handicap Inventory (THI);   EEG measures of spectral power and coherence
6 Recruiting Tinnitus rTMS 2013
Condition: Tinnitus
Interventions: Device: E-fied navigated rTMS;   Device: non-navigated rTMS;   Device: sham E-field navigated rTMS;   Device: Navigated rTMS
Outcome Measure: The change of loudness and pitch of the Tinnitus is psychophysically measured, VAS questionnaires, Tinnitus Handicap Inventory, Tinnitus diary
7 Not yet recruiting Investigating the Neurobiology of Tinnitus
Conditions: Tinnitus;   Traumatic Brain Injury;   Post Traumatic Stress Disorder
Intervention:
Outcome Measures: Development of Tinnitus;   Mild Traumatic Brain Injury;   Post Traumatic Stress Disorder
8 Recruiting Daily Bi-temporal Transcranial Random Noise Stimulation in Tinnitus
Condition: Chronic Tinnitus
Intervention: Device: Transcranial random noise stimulation (tRNS)
Outcome Measures: Number of treatment responders (response: Tinnitus Questionnaire total score reduction ≥ 5, contrast baseline versus end of treatment/week 12);   Change of Tinnitus severity as measured by the Tinnitus Questionnaire;   Change of Tinnitus severity as measured by the Tinnitus Numeric Rating Scales;   Change of depressive symptoms as measured by the Major Depression Inventory;   Change in quality of life as measured by the WHOQoL-Bref
9 Recruiting AM-101 in the Treatment of Acute Tinnitus 2
Condition: Tinnitus
Interventions: Drug: AM-101;   Drug: Placebo
Outcome Measures: Tinnitus loudness;   Tinnitus questionnaire;   Hearing threshold;   Adverse events and serious adverse events
10 Recruiting Repetitive Transcranial Magnetic Stimulation as a Treatment for Tinnitus
Condition: Tinnitus
Interventions: Device: repetitive transcranial magnetic stimulation (rTMS) 1;   Device: repetitive transcranial magnetic stimulation (rTMS) 2;   Device: repetitive transcranial magnetic stimulation (rTMS) 3;   Device: sham repetitive transcranial magnetic stimulation (rTMS) 4
Outcome Measures: Change of Tinnitus severity as measured by the visual analogue scale (VAS);   Beck's Depression Inventory (BDI);   State-Trait Anxiety Inventory (STAI);   Pittsburgh Sleep Quality Index (PSQI);   Tinnitus Handicap Inventory (THI)
11 Recruiting Commercial Lidocaine Patch as a Treatment for Ear-ringing
Condition: Tinnitus
Intervention: Drug: Transdermal Lidocaine
Outcome Measure: Tinnitus Functional Index (TFI)
12 Unknown  Zinc to Treat Tinnitus
Condition: Tinnitus
Intervention: Dietary Supplement: Zinc sulfate
Outcome Measures: Tinnitus loudness and annoyance;   Tinnitus handicap
13 Recruiting AM-101 in the Treatment of Acute Tinnitus 3
Condition: Tinnitus
Interventions: Drug: AM-101;   Drug: Placebo
Outcome Measures: Tinnitus loudness;   Hearing threshold;   Responders;   Tinnitus questionnaires;   Adverse events and serious adverse events
14 Unknown  Tinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template Development
Condition: Tinnitus
Intervention:
Outcome Measures: Correlated brain activity;   Tinnitus Severity Ratings
15 Not yet recruiting Efficacy of Internet and Smartphone Application-delivered Tinnitus Retraining Therapy
Condition: Tinnitus
Interventions: Drug: Ginkgo biloba;   Behavioral: modified Tinnitus retraining therapy (TRT)
Outcome Measure: Tinnitus Handicap Inventory (THI)
16 Not yet recruiting Deep TMS of the Left Auditory Cortex Using the HMCIPCC Coil, in the Treatment of Patients With Tinnitus.
Condition: Tinnitus
Intervention: Device: Deep Transcranial Magnetic Stimulation
Outcome Measures: TQ - Tinnitus questionnaire;   VAS (100 - worst possible Tinnitus related discomfort; 0 - wellness)
17 Recruiting A Comparison of the Benefits of Mindfulness Based Cognitive Therapy, Relaxation Therapy and a Waiting List Control in the Management of Distress in Chronic Tinnitus Patients
Condition: Tinnitus
Interventions: Other: No treatment waiting period;   Behavioral: Mindfulness Based Cognitive Therapy;   Behavioral: Relaxation Therapy
Outcome Measures: Change in Tinnitus Questionnaire score over time;   Change in Clinical Outcomes in Routine Evaluation (Outcome measure) score over time
18 Recruiting Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus
Condition: Tinnitus
Interventions: Device: VNS Treatment;   Device: VNS Control
Outcome Measures: Number of Serious Adverse Events;   Number of Adverse Events;   Minimum masking level (MML) in units of dB (decibels);   Tinnitus Handicap Inventory (THI);   Tinnitus Handicap Questionnaire (THQ)
19 Recruiting Research Project About Psychological Strain, Quality of Life and Emotional Awareness in Patients With Tinnitus
Condition: Tinnitus
Intervention: Other: observational research
Outcome Measures: Values of PRISM;   TAS;   Quality of life (SF-36), perceived grade of Tinnitus (THI, TF, TBF-12) and the clinical characteristic of Tinnitus.;   comorbidities
20 Not yet recruiting Effectiveness of Cannabis in the Treatment of Tinnitus Patients
Condition: Tinnitus
Interventions: Drug: Cannabis;   Drug: Placebo
Outcome Measure: Tinnitus handicap inventory score