Tired and Diaformin


Tired Symptoms and Causes

Everyone feels Tired now and then. Sometimes you may just want to stay in bed. But, after a good night's sleep, most people feel refreshed and ready to face a new day. If you continue to feel Tired for weeks, it's time to see your doctor. He or she may be able to help you find out what's causing your fatigue and recommend ways to relieve it.

Fatigue itself is not a disease. Medical problems, treatments, and personal habits can add to fatigue. These include

  • Taking certain medicines, such as antidepressants, antihistamines, and medicines for nausea and pain
  • Having medical treatments, like chemotherapy and radiation
  • Recovering from major surgery
  • Anxiety, stress, or depression
  • Staying up too late
  • Drinking too much alcohol or too many caffeinated drinks
  • Pregnancy

One disorder that causes extreme fatigue is chronic fatigue syndrome (CFS). This fatigue is not the kind of Tired feeling that goes away after you rest. Instead, it lasts a long time and limits your ability to do ordinary daily activities.

NIH: National Institute on Aging

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Tired treatment research studies

Diaformin clinical trials, surveys and public health registries

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Diaformin Side Effects

Fatigue (67)
Arterial Disorder (53)
Hunger (46)
Dyspnoea (45)
Blood Glucose Increased (34)
Angioneurotic Oedema (24)
Weight Decreased (21)
Vomiting (19)
Dehydration (18)
Renal Failure Acute (15)
Pernicious Anaemia (15)
Hypoglycaemia (14)

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Recent Reviews

<b>i feel sick all the time im on diaformin 850</b>

Been overdosed over nine months on 5700mg of Diaformin per dayby my GP. Had lost weight, loss of appetite anaemia B12 deficiency vitamin D deficiency lethagy pains in back on exertion etc. Rushed to hospital, no recordable blood sugar, acut

Dosage 3x500mg daily. Nausea, loss of appetite, Possibly also constipation.On Thyroxine,Tritace,Cardizem,Natrilix,Lipitor,Cartia. Because of the nausea myDiet therefore not well balanced any more which affects

Had to increase dosage to 1000mg twice a day. Immediately began to find it difficult to summon any energy to do any normal day to day acttivities eg washing, cooking. Diarhoea, lethargy, increase in thirst ( nothing quen

I am a type 2 diabetic 62 years of age, female,and recently my doctor has increased my Diafomin 1000g from two a day to three times a day...she has also stated me on a new Blood Presssure tablet called Avapro HCT 300/25 since I started them I have

I am diaform 500mg 3 times a day each time two tablets I have running stomach and I am very tired and very stress My diabetic is type 2


I first started with diaformin early August, I now have very bad diarohhea which has now strated for the last 4 days as a very dark green that flows like water. This happins after each meal.

I have been on diaformin for 3 months, I have type 2 diabettes and have an ongoing heart condition. Iam 51, i have noticed excessive sweating and feeling hot continually, also fatigue and the runs. i am on 3 tablets of 500mgs per day. my sugar leve

I have diabetes type 2 and I use 3 or 4 diaformin 500mg tablets daily and I have had great results with them - my blood sugar was about 17 plus after a light meal before using them and now is very slightly above 7 or max 9 after food intake.

since i started novothyral my pulse jumped, and tired,memory problems,my body feels week,unable to do anythyng physical, all in all my life going nowhere since two months ago when i started taking this pill thanks very much a

I am real tired I've been on coreg about two weeks, I don't know if Ican keep taking it. I am so sleepy all the time don't want to do anything my chest hurts. Don't know what to do, if Idon't take it my heart want work right. JUST STUCK

I just started taking lisinopril and am also staying very tired. Dizziness and lightheadness are my biggest problems right now.I am taking this with cardura and zoloft, so it may not count here. But i wanted to share my input and after reading the c

I took pataday for the first time around 10pm, I was instructed by my optometrist to take 1 drop in each eye every 24 hours, its now 530am, I think this stuff had made it so i cannot sleep! I'm super tired but I just cannot sleep! Thanks pataday...

Intersting on the Bicor . i have been on it since march this year , starting with 2.5 , then to 5.0 , 7.5 and 10mg for the last 3 months . always felt tired in the increse dosage as advised . but now have had a fe w joint aches , chest pains and cur

My symptoms were tired, weak, unable to sleep. Was prescribed half of a 15 MG Mirtazapine nightly to help me sleep. Has this drug been successful used as a sleeping aid?

&lt;b&gt;Describe Your Pradaxa Experience Here:&lt;/b&gt;tired and fluid retention

&lt;b&gt;Describe Your Seroxat Experience Here:&lt;/b&gt;Stomach and wierd vision and feeling tired

I feel very ,very (unusually) tired and lethargic, almost as if I'd been drugged - cannot stay awake, feel like a zombie. Cannot concentrate or focus on simple tasks and conversations. Alertness drops to almost zero.

<b>17 year old</b> I've resently just tried the benylin mucus and phlegm pills. They say to only take two but I'm wondering if that's a bit much because I feel tired and a little light headed awhile after to taking them. Is that suppo

Tired Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Acupuncture or MBSR for Patients With Fatigue and MS
Conditions: Fatigue;   Multiple Sclerosis
Interventions: Other: Usual care + acupuncture;   Other: usual care+mbsr;   Other: usual care
Outcome Measures: fatigue severity scale;   modified fatigue impact scale;   therapy response rates;   expanded disability status scale;   multipe sclerosis functional composite scale;   beck depression inventory II;   Body efficacy expectation;   SF-12;   HAQUAMS;   Costs;   overall treatment effect;   immune parameters;   number of serious adverse events;   number of suspected adverse reactions
2 Recruiting Cognitive Behavioral Therapy With or Without Armodafinil in Treating Cancer Survivors With Insomnia and Fatigue After Chemotherapy
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Procedure: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Other: Placebo;   Procedure: Fatigue Assessment and Management;   Procedure: Sleep Disorder Therapy;   Drug: Armodafinil;   Procedure: Quality-of-life assessment;   Procedure: Management of Therapy;   Procedure: Sleep disorder therapy;   Procedure: cognitive assessment;   Procedure: Quality of Life assessment;   Procedure: Fatigue assessment and management;   Procedure: Management of therapy and complications;   Procedure: Cognitive Assessment;   Procedure: Quality of Life Assessment;   Procedure: Fatifue assessment and management
Outcome Measures: Severity of insomnia as assessed by the insomnia severity index and daily sleeep diaries.;   Fatigue as assessed by the brief fatigue index;   Adverse Events;   Fatigue as assessed by the functional assessment of chronic illness therapy-fatigue;   Sleep latency, wake after sleep onset, and total sleep time
3 Not yet recruiting Fatigue Management in HIV
Condition: Fatigue
Interventions: Behavioral: Sleep and Rhythm Intervention;   Behavioral: Dietary Modifications
Outcome Measures: Morning fatigue severity;   Evening fatigue severity;   Lack of energy - frequency;   Lack of energy - severity;   Lack of energy - distress;   Attrition;   Satisfaction with the intervention;   Adherence to intervention;   Objectively measured sleep duration;   Objectively measured sleep quality;   Objectively-measured activity;   Sleep medication use;   Self-reported sleep quality;   Depressed mood;   Anxious mood;   Physical function;   Cognitive function;   Medication adherence;   Daytime sleepiness;   Fatigue interference with daytime function;   Sleep behavior
4 Unknown  Development and Evaluation of a Cancer-Related Fatigue Patient Education Program
Condition: Cancer-Related Fatigue
Intervention: Behavioral: Fatigue Patient Education Program (FIBS)
Outcome Measures: Fatigue;   Quality of Life, Depression and anxiety, physical activity
5 Recruiting Methylphenidate as Treatment Option of Fatigue in Multiple Sclerosis
Conditions: Multiple Sclerosis;   Fatigue
Interventions: Drug: Methylphenidate modified release;   Drug: Maltodextrin
Outcome Measures: Change of Fatigue as measured by Fatigue Severity Scale;   Change of Fatigue as measured by Modified Fatigue Impact Scale (MFIS)
6 Recruiting Treatment of Post-Traumatic Brain Injury (Post-TBI) Fatigue With Light Therapy
Conditions: Traumatic Brain Injury;   Fatigue
Interventions: Device: Bright White Light (BWL);   Device: Dim Red Light (DRL)
Outcome Measures: Multidimensional Assessment of Fatigue (MAF);   TBI-QOL Fatigue;   Neuro-QOL Depression and Sleep;   Epworth Sleepiness Scale (ESS);   CNS Vital Signs TBI Rehab Toolbox;   Cognitive Failures Questionnaire;   Neuro-QOL Anxiety;   Actiwatch Spectrum;   Satisfaction with Life Scale;   Treatment Satisfaction Questionnaire for Medication;   Credibility/Expectancy Questionnaire
7 Recruiting Fire Fighter Fatigue Management Program: Operation Fight Fatigue
Conditions: Shift-Work Sleep Disorder;   Insomnia;   Restless Leg Syndrome;   Obstructive Sleep Apnea;   Impaired Driving
Interventions: Behavioral: Sleep health education provided via a web-based program;   Other: Sleep disorder detection and treatment;   Other: Optimization of Sleep in Fire Station
Outcome Measures: Sleep and health screening of firefighters using a composite of survey instruments;   Composite of firefighter information provided by the participating fire department;   Sleep and performance of firefighters measured by a composite of physiological monitoring;   Documentation of motor vehicle crashes (MVC), and reported injuries;   Employment verification as a firefighter of all participants;   Composite of firefighter health information
8 Recruiting Biomarkers of Fatigue Related to Adjuvant Chemotherapy for Breast Cancer
Conditions: Fatigue;   Breast Cancer
Outcome Measure: Potential biomarkers related to chemotherapy induced fatigue
9 Recruiting PG2 Treatment for Improving Fatigue Among Advanced Cancer Patients Under Standard Palliative Care
Condition: Cancer-related Fatigue
Interventions: Drug: Astragalus Polysaccharides 500 mg;   Drug: Astragalus Polysaccharides 250 mg
Outcome Measures: Fatigue Improvement Response Rate;   The fatigue improvement response rate among patients within and between cycles (by BFI-T);   The fatigue improvement by multiple BFI-T score percentage change levels among patients between two study arms;   The mean of patients' fatigue score change from baseline within and between cycles (by BFI-T);   Symptoms and Quality of Life Assessments: SS11 from EORTC QLQ-C30 (including the evaluation of the quality of sleep, appetite, pain, fatigue, nausea, vomiting and global quality of life);   Karnofsky performance score;   The correlation between Weight change and the related blood c-reactive protein level;   Physical Examination;   Labolatory Safety Examination;   Incidence of Adverse Events as a Measure of Safety and Tolerability;   Vital signs
10 Not yet recruiting Sodium Oxybate in Patients With Chronic Fatigue Syndrome.
Condition: Chronic Fatigue Syndrome
Interventions: Drug: Sodium oxybate;   Drug: Placebo
Outcome Measures: Measurement of the effect of sodium oxybate on fatigue with questionnaires.;   Effect of sodium oxybate on sleepiness.;   Effect of sodium oxybate on sleepiness;   Effect of sodium oxybate on sleep quality.;   Effect of sodium oxybate on general health.;   Effect of sodium oxybate on pain.
11 Recruiting Oral Testosterone for Fatigue in Male Multiple Sclerosis Patients
Conditions: Multiple Sclerosis;   Fatigue
Interventions: Drug: Testosterone undecanoate;   Drug: placebo
Outcome Measures: Change in fatigue (measured with Modified Fatigue Impact Scale [M-FIS]);   Change in fatigue as measured on a visual analog scale (VAS);   Quality of life as measured with the Aging Males' Symptoms (AMS) scale;   Neurological status as measured with the Expanded Disability Status Scale (EDSS);   Number of participants with , type and severity of adverse events
12 Not yet recruiting Yoga Skills Training or Attention Control for Reducing Fatigue and Depressive Symptoms During Chemotherapy in Patients With Stage II-IV Colorectal Cancer
Conditions: Depressive Symptoms;   Fatigue;   Psychosocial Effects of Cancer and Its Treatment;   Stage IIA Colon Cancer;   Stage IIA Rectal Cancer;   Stage IIB Colon Cancer;   Stage IIB Rectal Cancer;   Stage IIC Colon Cancer;   Stage IIC Rectal Cancer;   Stage IIIA Colon Cancer;   Stage IIIA Rectal Cancer;   Stage IIIB Colon Cancer;   Stage IIIB Rectal Cancer;   Stage IIIC Colon Cancer;   Stage IIIC Rectal Cancer;   Stage IVA Colon Cancer;   Stage IVA Rectal Cancer;   Stage IVB Colon Cancer;   Stage IVB Rectal Cancer
Interventions: Behavioral: Yoga Skills Training (YST);   Other: questionnaire administration;   Other: fatigue and depressive symptom assessment and management;   Other: psychological stress assessment;   Other: laboratory biomarker analysis;   Other: Attention Control
Outcome Measures: Changes in fatigue (recalled);   Changes in depressive symptoms (recalled and daily);   Changes in daily fatigue;   Changes in psychological stress (daily and recalled) as assessed by Perceived Stress Scale (PSS);   Regulation of psychological stress (daily and recalled) as assessed by Positive and Negative Affect Schedule-Expanded Form and Cancer Behavior Inventory
13 Recruiting Exercise in Lessening Fatigue Caused by Cancer in Patients Undergoing Chemotherapy
Conditions: Fatigue;   Unspecified Adult Solid Tumor, Protocol Specific
Intervention: Behavioral: exercise
Outcome Measures: Improvement of cancer-related fatigue as assessed by the Brief Fatigue Inventory total score at day 41 (after exercise intervention);   Improvement of aerobic capacity, strength, and quality of life as assessed by the 6-minute walk test, handgrip dynamometry, and Functional Assessment of Chronic Illness Therapy-Fatigue total score at day 41 (after exercise intervention)
14 Recruiting American Ginseng to Improve HIV-Associated Fatigue: A Randomized, Placebo-Controlled, Parallel Design, Multiple-Dose Clinical Trial
Condition: HIV/AIDS-associated Fatigue
Interventions: Drug: American ginseng;   Dietary Supplement: Placebo for American ginseng
Outcome Measures: Change in Fatigue Severity Score;   Additional questionnaire will be used to quantify fatigue, quality of life, symptoms of depression, sleep quality, virologic, immunologic, and inflammatory markers.;   Additional questionnaire will be used to quantify fatigue, inflammatory, immunologic, and virologic markers, and side effects
15 Not yet recruiting Nasal Continuous Positive Airway Pressure (CPAP) in Chronic Fatigue and Sleep-disordered Breathing
Conditions: Chronic Fatigue With OSA;   Chronic Fatigue Syndrome With OSA
Intervention: Procedure: Active CPAP is compared with sham CPAP as a control intervention.
Outcome Measures: Continuous Positive Airway Pressure-responsiveness regarding fatigue after 28 days: baseline evaluation.;   Continuous Positive Airway Pressure-responsiveness regarding fatigue after 28 days: first treatment + effect evaluation.;   Continuous Positive Airway Pressure-responsiveness regarding fatigue after 28 days: second treatment + effect evaluation.;   The Continuous Positive Airway Pressure responsiveness regarding sleepiness and general health in the same target population: baseline evaluation.;   The Continuous Positive Airway Pressure responsiveness regarding sleepiness and general health in the same target population: first treatment + effect evaluation.;   The Continuous Positive Airway Pressure responsiveness regarding sleepiness and general health in the same target population: second treatment + effect evaluation.
16 Recruiting Developing Objective Fatigue Indicators in Colorectal Cancer Survivors.
Condition: Colorectal Cancer
Intervention: Behavioral: exercise education and walking program
Outcome Measure: Developing Objective Fatigue Indicators: Exploring the Relationships Among Fatigue, Muscle Power and Metabolomics Through Fatigue Management and Individualized Exercise Education Program in Colorectal Cancer Survivors
17 Unknown  Acupuncture for the Treatment of Chronic Post-Chemotherapy Fatigue
Condition: Fatigue
Interventions: Procedure: Acupuncture;   Procedure: Placebo Acupuncture
Outcome Measures: To determine whether acupuncture reduces chronic fatigue after chemotherapy more effectively than placebo;   To examine the long term effects of acupuncture treatment on fatigue;   To examine predictors of response to acupuncture treatment in terms of baseline symptoms, hemoglobin, age, sex, time since chemotherapy, and concurrent treatment;   To examine the effect of acupuncture on levels of physical activity and quality of life
18 Recruiting Investigating Molecular-Genetic Correlates of Fatigue Experienced by Cancer Patients Receiving Treatment
Conditions: Cancer;   Fatigue
Outcome Measures: The primary outcomes of this study are self-reported fatigue, depression, and quality of life scores of patients before, at midpoint, and at completion of each cycle of their cancer treatment.;   White blood cell gene expression;   Fatigue, cognitive function, and HRQOL scores;   Physical activity levels;   Skeletal muscle strength
19 Recruiting Fatigue Before and After Exercise in Patients With Advanced Cancer Stage
Condition: Fatigue
Interventions: Other: 10 minute walk;   Other: 20 minute walk;   Other: 30 minute walk
Outcome Measures: Fatigue;   Quality of life;   Anxiety and Depression Evaluation;   Patient impression satisfaction
20 Recruiting Treatment of Post Stroke Fatigue With a Wakefulness Promoting Agent
Conditions: Stroke;   Post Stroke Fatigue
Interventions: Drug: modafinil;   Drug: placebo
Outcome Measures: Multidimensional Fatigue Inventory (MFI- 20);   MFI-20;   Fatigue severity scale (FSS);   FSS