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VISION BLURRED and Clonidine

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VISION BLURRED Symptoms and Causes

What is high blood pressure in pregnancy?

Blood pressure is the force of your blood pushing against the walls of your arteries as your heart pumps blood. High blood pressure, or hypertension, is when this force against your artery walls is too high. There are different types of high blood pressure in pregnancy:

  • Gestational hypertension is high blood pressure that you develop while you are pregnant. It starts after you are 20 weeks pregnant. You usually don't have any other symptoms. In many cases, it does not harm you or your baby, and it goes away within 12 weeks after childbirth. But it does raise your risk of high blood pressure in the future. It sometimes can be severe, which may lead to low birth weight or preterm birth. Some women with gestational hypertension do go on to develop preeclampsia.
  • Chronic hypertension is high blood pressure that started before the 20th week of pregnancy or before you became pregnant. Some women may have had it long before becoming pregnant, but didn’t know it until they got their blood pressure checked at their prenatal visit. Sometimes chronic hypertension can also lead to preeclampsia.
  • Preeclampsia is a sudden increase in blood pressure after the 20th week of pregnancy. It usually happens in the last trimester. In rare cases, symptoms may not start until after delivery. This is called postpartum preeclampsia. Preeclampsia also includes signs of damage to some of your organs, such as your liver or kidney. The signs may include protein in the urine and very high blood pressure. Preeclampsia can be serious or even life-threatening for both you and your baby.
What causes preeclampsia?

The cause of preeclampsia is not known.

Who is at risk for preeclampsia?

You are at higher risk of preeclampsia if you

  • Had chronic high blood pressure or chronic kidney disease before pregnancy
  • Had high blood pressure or preeclampsia in a previous pregnancy
  • Have obesity
  • Are over age 40
  • Are pregnant with more than one baby
  • Are African American
  • Have a family history of preeclampsia
  • Have certain health conditions, such as diabetes, lupus, or thrombophilia (a disorder which raises your risk of blood clots)
  • Used in vitro fertilization, egg donation, or donor insemination
What problems can preeclampsia cause?

Preeclampsia can cause

  • Placental abruption, where the placenta separates from the uterus
  • Poor fetal growth, caused by a lack of nutrients and oxygen
  • Preterm birth
  • A low birth weight baby
  • Stillbirth
  • Damage to your kidneys, liver, brain, and other organ and blood systems
  • A higher risk of heart disease for you
  • Eclampsia, which happens when preeclampsia is severe enough to affect brain function, causing seizures or coma
  • HELLP syndrome, which happens when a woman with preeclampsia or eclampsia has damage to the liver and blood cells. It is rare, but very serious.
What are the symptoms of preeclampsia?

Possible symptoms of preeclampsia include

  • High blood pressure
  • Too much protein in your urine (called proteinuria)
  • Swelling in your face and hands. Your feet may also swell, but many women have swollen feet during pregnancy. So swollen feet by themselves may not be a sign of a problem.
  • Headache that does not go away
  • Vision problems, including blurred vision or seeing spots
  • Pain in your upper right abdomen
  • Trouble breathing
  • Eclampsia can also cause seizures, nausea and/or vomiting, and low urine output. If you go on to develop HELLP syndrome, you may also have bleeding or bruising easily, extreme fatigue, and liver failure.

    How is preeclampsia diagnosed?

    Your health care provider will check your blood pressure and urine at each prenatal visit. If your blood pressure reading is high (140/90 or higher), especially after the 20th week of pregnancy, your provider will likely want to run some tests. They may include blood tests other lab tests to look for extra protein in the urine as well as other symptoms.

    How is preeclampsia treated?

    Delivering the baby can often cure preeclampsia. When making a decision about treatment, your provider take into account several factors. They include how severe it is, how many weeks pregnant you are, and what the potential risks to you and your baby are:

    • If you are more than 37 weeks pregnant, your provider will likely want to deliver the baby.
    • If you are less than 37 weeks pregnant, your health care provider will closely monitor you and your baby. This includes blood and urine tests for you. Monitoring for the baby often involves ultrasound, heart rate monitoring, and checking on the baby's growth. You may need to take medicines, to control your blood pressure and to prevent seizures. Some women also get steroid injections, to help the baby's lungs mature faster. If the preeclampsia is severe, you provider may want you to deliver the baby early.

    The symptoms usually go away within 6 weeks of delivery. In rare cases, symptoms may not go away, or they may not start until after delivery (postpartum preeclampsia). This can be very serious, and it needs to be treated right away.

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Clonidine Side Effects

Blood Pressure Increased (136)
Completed Suicide (121)
Hypotension (117)
Hypertension (95)
Product Adhesion Issue (72)
Headache (68)
Product Substitution Issue (64)
Dizziness (62)
Dyspnoea (55)
Product Quality Issue (54)
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Cardiac Arrest (47)
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Fatigue (41)
Anxiety (40)
Asthenia (39)
Overdose (38)
Pain (35)
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Feeling Abnormal (32)
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Lethargy (31)
Depression (30)
Heart Rate Increased (30)
Sinus Bradycardia (30)
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Hypertensive Crisis (29)
Vomiting (28)
Respiratory Arrest (28)
Chest Pain (26)
Blood Pressure Decreased (25)
Syncope (25)
Convulsion (24)
Cardio-respiratory Arrest (24)
Rash (23)
Application Site Rash (23)
Blood Pressure Inadequately Controlled (22)
Insomnia (22)
Cerebrovascular Accident (22)
Hyperhidrosis (21)
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Tremor (19)
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Recent Reviews

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I find this medication terrible. I dont know aboutanyone else but I have found that my body has become addictived to this drug. I have only been on this drug since June 18, 2010. I am on the patch 2mg plusone 1 mg tablet 2x per da

I just started on Clonidine for excessive sweating of the scalp and face, but also for insomnia. I had to take .3 mg to get sleepy. I woke up this morning with several canker like sores on the inside of my lips. Anyone else had this happen? I als

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My goodness. I believe every one of those persons talking about this medicine. It is so true and I've only been on it not even a month and I have all of those symptoms. I am so tired of falling asleep anywhere.

fROM THE DAY i GOT THE INJECTION aCLASTA, i AM FEELING GIDDY AND HAVE LOST MY VISION. w WHAT IS YOUR RESPONSIBILITY ABOUT THIS fROM THE DAY i GOT aCLASTA INJECTION, i AM FEELING

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VISION BLURRED Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Safety of Clonidine in Infants With Hypoxic Ischemic Encephalopathy During Therapeutic Hypothermia
Condition: Encephalopathy, Hypoxic-Ischemic
Intervention: Drug: Clonidine (Duraclon®)
Outcome Measures: Maximum-tolerated dose of Clonidine;   Clonidine Plasma levels;   Time to onset of shivering after Clonidine;   shivering
2 Not yet recruiting The Effect of Clonidine-enhanced Sedation on Delirium in Ventilated Critically Ill Patients
Condition: Delirium
Interventions: Drug: Clonidine;   Drug: SodiumChloride
Outcome Measures: CAM-ICU (Confusion Assessment Method for the Intesive Care Unit);   Signs of agitation;   Opiate use;   Sedative use;   Anti-psychotic use;   Ventilation free days;   Sedation free days
3 Not yet recruiting Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain
Condition: Labor Pain
Interventions: Drug: Clonidine or Fentanyl;   Drug: Clonidine or fentanyl
Outcome Measures: Pain Score on a VAS scale;   Maternal blood pressure;   Maternal heart rate;   Neonatal Apgar score;   Number of spontaneous vaginal deliveries
4 Recruiting A Comparison of Ropivacaine Alone Versus Combination of Dexamethasone and Clonidine for Block
Condition: Upper Extremity Fracture
Interventions: Drug: Ropivacaine;   Drug: Ropivacaine and dexamethasone;   Drug: Ropivacaine, dexamethasone, Clonidine;   Drug: Ropivacaine and Clonidine
Outcome Measures: Duration of the supraclavicular block;   Postoperative analgesia
5 Recruiting Combination of Dronabinol and Clonidine for Cannabis Dependence in Patients With Schizophrenia
Conditions: Cannabis Dependence;   Marijuana Dependence
Interventions: Drug: Dronabinol;   Drug: Clonidine;   Drug: Placebo
Outcome Measures: Change from baseline in cannabis use at 10 weeks;   Change in withdrawal symptoms from baseline at 10 weeks;   Change from baseline in cannabis use at 14 weeks;   Change in withdrawal symptoms from baseline at 14 weeks
6 Unknown  Use of Transdermal Clonidine in Trauma Patients
Condition: Delirium
Interventions: Drug: Clonidine;   Drug: Placebo
Outcome Measures: Duration of mechanical ventilation following administration of the first dose of Clonidine or placebo;   Incidence and duration in hours of delirium currently used;   Time to pass first SBT following administration of the first dose of Clonidine or placebo;   Mean incidence and duration of delirium
7 Recruiting Effectiveness of Perineural Clonidine as an Adjuvant With Ropivacaine for Popliteal Nerve Block in Patients Undergoing Foot and Ankle Surgery
Condition: Pain
Interventions: Drug: Clonidine;   Drug: ropivacaine
Outcome Measures: Compare the onset of sensory and motor block between the control group and the control group;   Compare the duration of sensory and motor block between the control group and the control group;   Compare the mean VAS scores at 24 hours post procecure to determine the effectiveness of perineural Clonidine on duration of postoperative analgesia;   Compare the number of subjects taking postoperative opioids to determine the effect of perineural Clonidine versus placebo;   Compare the subjects mean blood pressure effect of perineural Clonidine versus placebo;   number of subjects in each group requiring sedation;   Determine the effect of perineural Clonidine versus placebo on time to discharge;   Determine the effect of perineural Clonidine versus placebo on postoperative time to first analgesic intake;   Compare the mean VAS scores at 24 hours post procedure to determine the patient satisfaction of perineural Clonidine on duration of postoperative analgesia
8 Recruiting Solifenacin Compared to Clonidine for Reducing Hot Flashes Among Breast Cancer Patients
Conditions: Hot Flashes;   Breast Cancer
Interventions: Drug: solifenacin;   Drug: Clonidine
Outcome Measures: hot flash composite and frequency scores (daily diary);   number of clinician-rated adverse events;   daily functioning (Hot Flash-Related Daily Interference score);   sleep (Insomnia Severity Index);   quality of life (Illness Cognition Questionnaire, SF-12)
9 Recruiting Efficacy of Clonidine and Propranolol in Dentistry (AAA)
Condition: Anxiety
Interventions: Drug: Clonidine;   Drug: Propranolol;   Drug: Placebo
Outcome Measures: Change from baseline in modified dental anxiety scale(MDAS)and vital signs (blood pressure, heart rate, respiratory rate, oxygen saturation) until four hours post treatment;   Changes in Verbal Numerical Rating Scale (VNRS) at three, six, and twenty-four hours post treatment
10 Unknown  Neonatal Spinal Anesthesia: Effects of the Addition of Clonidine
Conditions: Spinal Anesthesia;   Neonates
Intervention: Drug: Clonidine
Outcome Measures: number of "rescue" general anesthesia;   apnea and desaturation occurrence;   duration of spinal anesthesia
11 Recruiting The Addition of Clonidine to 0.2% Ropivacaine for Wound Instillation After Minor Lower Abdominal Surgery in Children
Conditions: Hernia, Inguinal;   Hydrocele
Intervention: Drug: Clonidine
Outcome Measures: Time to first analgesia after procedure;   continuous pain scores (modified Children's Hospital of Eastern Ontario Pain Score [mCHEOPS], modified Wong-Baker Faces);   sedation scores;   emergence delirium score (Pediatric Anesthesia Emergence Delirium [PAED]);   total analgesics consumed;   total sedation consumed
12 Recruiting Assessment of the Effect of Clonidine for Cataract Surgery
Conditions: Pain;   Arrythmia
Interventions: Drug: Clonidine;   Drug: placebo
Outcome Measures: intensity of pain;   intraocular pressure
13 Recruiting Added Value of Local Clonidine for Spine Postoperative Pain Control, in Addition to Bupivacaine
Condition: Post-operative Pain
Interventions: Drug: Bupivacaine;   Drug: Clonidine
Outcome Measures: Mean Area under curve;   Area under Curve (AUC) of pain;   Daily rescue opiates consumption;   Global subjective patient satisfaction of post-operative wound pain control
14 Not yet recruiting Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery
Conditions: Shoulder Arthroscopy;   Knee Arthroscopy
Interventions: Drug: Sugar pill;   Drug: Gabapentin;   Drug: Clonidine
Outcome Measures: Postoperative Pain using a Verbal Rating Scale (VRS);   Opioid consumption obtained from the recorded data;   postoperative nausea and vomiting using a Verbal Rating Scale;   return to normal activities of daily living using follow up questionnaires;   Patient satisfaction using a verbal rating scale from 0 to 100
15 Recruiting Clonidine for Relapse Prevention in Buprenorphine-Maintenance Patients
Condition: Opioid-Related Disorders
Interventions: Drug: Clonidine;   Drug: Placebo
Outcome Measures: Opiate-negative urine screens;   HIV risk behaviors;   Craving
16 Unknown  Clonidine in Femoral Nerve Block Surgery in Children
Condition: Other Reconstructive Surgery
Interventions: Drug: Ropivacaine;   Drug: Clonidine
Outcome Measures: Pain;   Heart rate;   Blood pressure;   Oxygen saturation
17 Recruiting The Oslo Study of Clonidine in Elderly Patients With Delirium
Condition: Delirium
Interventions: Drug: Clonidine;   Drug: Placebo
Outcome Measures: MDAS (Memorial delirium assessment scale);   Time-to-first delirium;   Incidence of "full-scale" delirium;   Severity of delirium;   Delirium subtype;   The use of "rescue medication";   Length of hospital stay;   Patient distress;   Side effects of Clonidine;   Pharmacokinetic response to Clonidine;   Pharmacodynamic response to Clonidine;   Biomarkers;   Institutionalization;   Survival;   Cognitive function/ independence
18 Recruiting The Value of Adding Either Meperdine or Fentanyl to Clonidine-bupivacaine
Condition: Amputation Stumps
Interventions: Drug: Meperdine;   Drug: Fentanyl
Outcome Measures: the hemodynamic effects .;   the analgesic efficacy.
19 Recruiting Efficacy and Safety Study of Clonidine Lauriad® to Treat Oral Mucositis
Condition: Oral Mucositis
Interventions: Drug: Clonidine Lauriad® 50µg;   Drug: Clonidine Lauriad® 100µg;   Drug: Placebo Lauriad®
Outcome Measures: Percentage of patients with an oral mucositis score≥ 3 using the WHO scale at cumulative radiation dose of 50 Gy;   Percentage of patients with an oral mucositis score≥ 3 using the WHO scale at cumulative radiation doses of 40 Gy and 60 Gy
20 Recruiting Safety and Efficacy Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathy
Conditions: Painful Diabetic Neuropathy;   Diabetic Neuropathy;   Neuropathy
Intervention: Drug: Clonidine Gel 0.1%
Outcome Measures: Change in average pain score over time.;   Mean daily average pain intensity Numeric Pain Rating Scale scores over time.;   Mean daily worst pain intensity Numeric Pain Rating Scale scores