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VISION BLURRED and Concerta

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VISION BLURRED Symptoms and Causes

What is high blood pressure in pregnancy?

Blood pressure is the force of your blood pushing against the walls of your arteries as your heart pumps blood. High blood pressure, or hypertension, is when this force against your artery walls is too high. There are different types of high blood pressure in pregnancy:

  • Gestational hypertension is high blood pressure that you develop while you are pregnant. It starts after you are 20 weeks pregnant. You usually don't have any other symptoms. In many cases, it does not harm you or your baby, and it goes away within 12 weeks after childbirth. But it does raise your risk of high blood pressure in the future. It sometimes can be severe, which may lead to low birth weight or preterm birth. Some women with gestational hypertension do go on to develop preeclampsia.
  • Chronic hypertension is high blood pressure that started before the 20th week of pregnancy or before you became pregnant. Some women may have had it long before becoming pregnant, but didn't know it until they got their blood pressure checked at their prenatal visit. Sometimes chronic hypertension can also lead to preeclampsia.
  • Preeclampsia is a sudden increase in blood pressure after the 20th week of pregnancy. It usually happens in the last trimester. In rare cases, symptoms may not start until after delivery. This is called postpartum preeclampsia. Preeclampsia also includes signs of damage to some of your organs, such as your liver or kidney. The signs may include protein in the urine and very high blood pressure. Preeclampsia can be serious or even life-threatening for both you and your baby.
What causes preeclampsia?

The cause of preeclampsia is not known.

Who is at risk for preeclampsia?

You are at higher risk of preeclampsia if you

  • Had chronic high blood pressure or chronic kidney disease before pregnancy
  • Had high blood pressure or preeclampsia in a previous pregnancy
  • Have obesity
  • Are over age 40
  • Are pregnant with more than one baby
  • Are African American
  • Have a family history of preeclampsia
  • Have certain health conditions, such as diabetes, lupus, or thrombophilia (a disorder which raises your risk of blood clots)
  • Used in vitro fertilization, egg donation, or donor insemination
What problems can preeclampsia cause?

Preeclampsia can cause

  • Placental abruption, where the placenta separates from the uterus
  • Poor fetal growth, caused by a lack of nutrients and oxygen
  • Preterm birth
  • A low birth weight baby
  • Stillbirth
  • Damage to your kidneys, liver, brain, and other organ and blood systems
  • A higher risk of heart disease for you
  • Eclampsia, which happens when preeclampsia is severe enough to affect brain function, causing seizures or coma
  • HELLP syndrome, which happens when a woman with preeclampsia or eclampsia has damage to the liver and blood cells. It is rare, but very serious.
What are the symptoms of preeclampsia?

Possible symptoms of preeclampsia include

  • High blood pressure
  • Too much protein in your urine (called proteinuria)
  • Swelling in your face and hands. Your feet may also swell, but many women have swollen feet during pregnancy. So swollen feet by themselves may not be a sign of a problem.
  • Headache that does not go away
  • Vision problems, including blurred vision or seeing spots
  • Pain in your upper right abdomen
  • Trouble breathing
  • Eclampsia can also cause seizures, nausea and/or vomiting, and low urine output. If you go on to develop HELLP syndrome, you may also have bleeding or bruising easily, extreme fatigue, and liver failure.

    How is preeclampsia diagnosed?

    Your health care provider will check your blood pressure and urine at each prenatal visit. If your blood pressure reading is high (140/90 or higher), especially after the 20th week of pregnancy, your provider will likely want to run some tests. They may include blood tests other lab tests to look for extra protein in the urine as well as other symptoms.

    How is preeclampsia treated?

    Delivering the baby can often cure preeclampsia. When making a decision about treatment, your provider take into account several factors. They include how severe it is, how many weeks pregnant you are, and what the potential risks to you and your baby are:

    • If you are more than 37 weeks pregnant, your provider will likely want to deliver the baby.
    • If you are less than 37 weeks pregnant, your health care provider will closely monitor you and your baby. This includes blood and urine tests for you. Monitoring for the baby often involves ultrasound, heart rate monitoring, and checking on the baby's growth. You may need to take medicines, to control your blood pressure and to prevent seizures. Some women also get steroid injections, to help the baby's lungs mature faster. If the preeclampsia is severe, you provider may want you to deliver the baby early.

    The symptoms usually go away within 6 weeks of delivery. In rare cases, symptoms may not go away, or they may not start until after delivery (postpartum preeclampsia). This can be very serious, and it needs to be treated right away.

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Concerta Side Effects

Aggression (151)
Headache (146)
Suicidal Ideation (145)
Depression (130)
Insomnia (126)
Suicide Attempt (124)
Growth Retardation (119)
Weight Decreased (108)
Tachycardia (106)
Decreased Appetite (102)
Hallucination (94)
Overdose (92)
Chest Pain (91)
Abnormal Behaviour (89)
Psychotic Disorder (85)
Agitation (84)
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Vomiting (76)
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Tic (75)
Hypertension (75)
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Fatigue (63)
Heart Rate Increased (62)
Syncope (57)
Hallucination, Visual (56)
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Feeling Abnormal (46)
Restlessness (44)
Weight Increased (43)
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Psychomotor Hyperactivity (39)
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VISION BLURRED Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting A Study Comparing Long-acting Methylphenidate (ConcertaTM) vs. Placebo in the Treatment of Memory Loss Due to HIV
Condition: HIV Dementia
Interventions: Drug: Long acting methylphenidate;   Drug: Matched placebo
Outcome Measures: Change in rate of reaction time as measured by neuropsychological testing;   Number of Subjects with Adverse Events as Measures of Safety and Tolerability of Concerta in HIV infected adults
2 Recruiting Effects of Methylphenidate (Ritalin®) on the Neural Basis of Anxiety
Condition: PTSD
Interventions: Drug: Methylphenidate;   Drug: Placebo
Outcome Measures: Changes in blood oxygenation level-dependent BOLD signal responses;   Changes in BOLD signal responses;   Changes in skin conductance response;   Latency and accuracy during a interoceptive stimulus task
3 Not yet recruiting The Effect of Ritalin (Methylphenidate Hydrochloride) on Pain and Auditory Sensitivity: an Exploratory Double-blind Randomized Controlled Trial on Healthy Subjects
Condition: Pharmacological Action (PA)
Interventions: Drug: methylphenidate hydrochloride;   Drug: Sugar pill (placebo)
Outcome Measures: Experimental pain intensity measured on a visual analogue scale (0-100);   effect of Ritalin on auditory sensitivity, measured by the response to different auditory stimulations;   pain intensity (NPS 0-100) in response to thermal stimuli and the measures of the auditory tests.
4 Not yet recruiting Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI
Condition: Traumatic Brain Injury
Interventions: Drug: methylphenidate;   Drug: Placebo
Outcome Measures: Relationship between tonic dopamine release (measured by displacement of [11C]-raclopride by oral methylphenidate) and change in processing speed between baseline and after methylphenidate treatment.;   Relationship between D2/D3 receptor availability in ventral striatum and prefrontal cortex and neuropsychologic deficits.;   Relationship between tonic dopamine release in the ventral striatum and prefrontal cortex with neuropsychologic deficits after TBI.;   Relationship between D2/D3 receptor availability and functional connectivity of the prefrontal cortex with nodes of the default mode network.;   Relationship between TMS-induced short-interval cortical inhibition of M1 and tonic dopamine release.;   Test motivation and reward on and off methylphenidate in TBI patients.
5 Recruiting Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study
Conditions: Healthy;   Substance-related Disorder;   Mood Disorder
Interventions: Drug: Methylphenidate;   Drug: Modafinil;   Drug: MDMA;   Drug: Placebo
Outcome Measures: Effect on amygdala and striatum BOLD signal responses to emotional stimuli;   Effects on cognitive performance and associated BOLD signal changes in frontal areas;   Subjective effects;   Neuroendocrine effects;   Empathy and social behavior;   Physiological effects of methylphenidate, modafinil, and MDMA;   Genetic Polymorphisms;   Pharmacokinetics of methylphenidate, modafinil, and MDMA
6 Recruiting Methylphenidate vs. Risperidone for the Treatment of Children and Adolescents With ADHD and Disruptive Disorders
Conditions: Attention Deficit/Hyperactivity Disorder;   Oppositional Defiant Disorder;   Conduct Disorder
Interventions: Drug: Methylphenidate;   Drug: Risperidone
Outcome Measures: Change from baseline of aggressive behaviors.;   Clinical Global Impression - Improvement scale (CGI-I) questionnaire;   ADHD-RS questionnaire;   Children's Depression Rating Scale (CDRS) questionnaire;   Young Mania Rating Scale (YMRS) questionnaire;   Children Sleep Habits Questionnaire (CSHQ);   Clinical Global Impression - Severity (CGI-S) questionnaire
7 Unknown  Study of Methylphenidate as Add on Therapy in Depressed Cancer Patients
Condition: Depression
Interventions: Drug: Methylphenidate;   Drug: Placebo
Outcome Measures: depressive symptoms;   Distress level
8 Recruiting Methylphenidate for Attention Problems After Pediatric TBI
Conditions: Traumatic Brain Injury;   TBI;   ADHD
Interventions: Drug: Methylphenidate;   Drug: Placebo
Outcome Measures: Parent report measures;   Neuropsychological Testing;   Teacher Report Measures
9 Recruiting Methylphenidate to Improve Balance and Walking in MS
Condition: Multiple Sclerosis
Interventions: Drug: Methylphenidate (Ritalin);   Drug: Placebo
Outcome Measures: Timed Up and Go time (TUG time);   Automatic Postural Response (APR) Latency (in sec);   Timed 25 Foot Walk (T25FW in secs);   Pittsburgh Sleep Quality Assessment Questionnaire score;   Modified Fatigue Index Scale score;   Vestibular-Ocular Reflex time (in secs)
10 Not yet recruiting Methylphenidate on Intracortical Inhibition in Methamphetamine Abusers Attention Deficit Hyperactivity Disorder (ADHD)
Condition: Attention Deficit Hyperactivity Disorder
Intervention: Other: methylphenidate tablets and Inter-stimulus Intervals (ISI)
Outcome Measures: Conners ADHD Rating Scale;   Change of Motor Evoked Potential (MEP)
11 Recruiting Methylphenidate as Treatment Option of Fatigue in Multiple Sclerosis
Conditions: Multiple Sclerosis;   Fatigue
Interventions: Drug: Methylphenidate modified release;   Drug: Maltodextrin
Outcome Measures: Change of Fatigue as measured by Fatigue Severity Scale;   Change of Fatigue as measured by Modified Fatigue Impact Scale (MFIS)
12 Recruiting Multimodal Therapy for Treatment of Fatigue
Condition: Prostate Cancer
Interventions: Other: Placebo;   Drug: Methylphenidate;   Behavioral: Counseling Sessions;   Other: Sham Exercise;   Other: Standardized Exercise Intervention Program;   Other: Cognitive Behavioral Therapy (CBT)
Outcome Measure: Change in Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F) subscale scores
13 Recruiting Control of Cognition
Conditions: Healthy;   Attention Deficit Hyperactivity Disorder;   Alcohol Dependence;   Attention Deficit Hyperactivity Disorder and Alcohol Dependence
Interventions: Drug: Methylphendiate;   Drug: Naltrexone;   Drug: Placebo
Outcome Measures: Identify abnormalities in prefrontal control neural circuits underlying attention control, motor control, and appetitive control;   Characterize effects of methylphenidate and naltrexone on neural circuits in prefrontal cortex associated with attention control, motor control, and appetitive control;   Reaction time on the Multi-Source Interference Task;   Accuracy on the Multi-Source Interference Task;   Reaction time variability on the Multi-Source Interference Task
14 Recruiting The Effect of Methylphenidate Treatment in Familial Attention Deficit/Hyperactivity Disorder (ADHD)
Conditions: Attention Deficit/Hyperactivity Disorder Combined Type;   ADHD Predominantly Inattentive Type;   ADHD Predominantly Hyperactivity Type;   ADHD-not Other Specified
Intervention: Drug: Methylphenidate- Ritalin IR (Immediate Release)
Outcome Measures: Clinical Global Impression-Improvement scale;   overall ADHD-Rating Scale (ADHD-RS) score
15 Unknown  Amantadine Versus Ritalin in the Treatment of Attention Deficit Hyperactivity Disorder (ADHD)
Condition: Attention Deficit Hyperactivity Disorder
Interventions: Drug: Amantadine;   Drug: ritalin
Outcome Measure: The mean decrease in ADHD -RS-IV score from baseline will be used as the main outcome measure of response of ADHD treatment.
16 Not yet recruiting Identifying Characteristic Signature of Attention Deficit / Hyperactivity Disorder (ADHD) and Ritalin Treatment
Condition: "Attention Deficit Hyperactivity Disorder"
Interventions: Drug: Ritalin;   Drug: Placebo
Outcome Measure: Resting oscillation activity and Event-related-Potentials in Attention Deficit / Hyperactivity Disorder (ADHD) and healthy subjects.
17 Not yet recruiting Reversal of General Anesthesia With Methylphenidate
Conditions: Post Operative Cognitive Dysfunction;   Emergence From Anesthesia
Intervention: Drug: Methylphenidate
Outcome Measures: Number of Participants with Adverse Events as a Measure of Safety and Tolerability;   Time to emergence from general anesthesia
18 Recruiting A Comparison of Methylphenidate and Cognitive Behavioural Therapy for the Treatment of Binge Eating Disorder
Condition: Binge-Eating Disorder
Interventions: Drug: Methylphenidate;   Behavioral: Cognitive Behavioral Therapy
Outcome Measures: Frequency of binge episodes/days, as assessed by prospective daily binge diary;   Frequency of objective binge episodes and overall illness severity, as assessed by both the Eating Disorder Examination Interview and Questionnaire;   Clinician impression of illness severity and improvement, as assessed by the Clinical Global Impression scale;   Quality of life, as assessed by the Quality of Life Inventory;   Associated features of binge eating as captured by the Dutch Eating Behavior Questionnaire and Binge Eating Scale;   Body Mass Index
19 Recruiting Impact of CES1 Genotype on Metabolism of Methylphenidate
Conditions: Carboxylesterase 1 (CES1) Genotype;   CES1 Activity
Intervention: Drug: Methylphenidate
Outcome Measures: Plasma concentration of methylphenidate and ritalinic acid;   Metabolomic Profile
20 Not yet recruiting Methylphenidate ER Liquid Formulation in Adults With ASD and ADHD
Conditions: Attention-deficit/Hyperactivity Disorder;   Autism Spectrum Disorder
Intervention: Drug: Methylphenidate extended-release liquid formulation
Outcome Measure: Adult ADHD Investigator Symptom Report Scale (AISRS)