Acute and Prednisone


Acute Symptoms and Causes

Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, however, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In Acute myeloid leukemia (AML), there are too many of a specific type of white blood cell called a myeloblast.

AML is the most common type of Acute leukemia in adults. This type of cancer usually gets worse quickly if it is not treated. Possible risk factors include smoking, previous chemotherapy treatment, and exposure to radiation.

Symptoms of AML include:

  • Fever
  • Shortness of breath
  • Easy bruising or bleeding
  • Bleeding under the skin
  • Weakness or feeling tired
  • Weight loss or loss of appetite

Tests that examine the blood and bone marrow diagnose AML. Treatments include chemotherapy, other drugs, radiation therapy, stem cell transplants, and targeted therapy. Targeted therapy uses substances that attack cancer cells without harming normal cells. Once the leukemia is in remission, you need additional treatment to make sure that it does not come back.

NIH: National Cancer Institute

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Prednisone Side Effects

Dyspnoea (309)
Pyrexia (283)
Nausea (273)
Pain (263)
Diarrhoea (255)
Arthralgia (247)
Fatigue (246)
Headache (234)
Pneumonia (231)
Pain In Extremity (210)
Asthenia (210)
Vomiting (205)
Dizziness (201)
Oedema Peripheral (198)
Weight Increased (187)
Weight Decreased (175)
Abdominal Pain (172)
Back Pain (169)
Condition Aggravated (161)
Anaemia (156)
Crohn's Disease (113)
Sepsis (110)
Osteonecrosis (105)
Dehydration (104)
Malaise (104)
Fall (101)
Insomnia (100)
Death (100)
Injection Site Pain (100)
Chest Pain (97)
Cough (96)
Confusional State (96)
Diabetes Mellitus (91)
Rash (89)
Blood Glucose Increased (88)
Anxiety (88)
Pulmonary Embolism (88)
Rheumatoid Arthritis (85)
Pruritus (83)
Hypertension (82)
Hypotension (80)
Depression (80)
Febrile Neutropenia (79)
Erythema (78)
Renal Failure (77)
Neutropenia (74)
Deep Vein Thrombosis (73)
Renal Failure Acute (71)
Hyperglycaemia (69)
Muscular Weakness (69)

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Recent Reviews

>:o :'(

3 weeks after i had been given 120m of predisone in a 24 hour period,i started getting dizzy spells severe enough that initially i blacked out while driving,needless to say i havent been driving my car,but i still am experiencing very bad dizzy spell

66 year old male. Good to excellent health. Non smoker, non drinker. Slowly deteriorated till all joints were swollen and eventually I became 99% immobile. Diagnosis? Spotless, Rocky Mountain Spotted Fever. (erlickiosis chaffnesis) Hospitalized, inf

Chronic pancreatitis on CT scan

Female patient 39 taking prednisone for asthma. Prednisone 20 mg 4 days on and then one day off/one day onfor8 days. Menstrual type bleeding although not during menstrual period. Severe pelvic cramps and urgency of urination. Swol

I am asthmatic (since I was very little) 36yrs old, took 40mg Prednisone for 8 days - two days later I ovulated and then I started bleeding uncontrollably. Gynae said ovaries failed as blood work tested very low and put me on Duphaston to aid drying

I have taken Prednisone for severe asthma on many occassions (including IV in hospital for 7 days) and suffered severe abdominal pain. Three years ago a gastroscopy revealed I had Duodenal ulcers and Gastritis, most likely caused from the Prednisilo

I take it when i get poison oak or ivy really bad and it takes it away in like 3 days if im fully broken out and i am highly allergic poison ivy, oak and all of that other stuff like that and this stuff helps me tremendously :-D

I take prednione 10mg : 3 tablets once daily for 3 days,then 2 tablets once daily for 3 days,then 1 tabletonce daily for 3 days, then hallf tablets for 4 days. Prednisone give more energy because I have Refractory Anemia with Ringed oblast

I was on a higher dosage - 40mg for 8 days and a few days after I stopped, I started with a 'breakthrough' bleed. Had to have blood tests taken and it showed ovarian failure which DR said could be strongly linked to Prednisone... I am not convinced i

<span style='color: #808080;'><b>Describe Your Injection site swelling from INFLUENZA (H1N1) (H1N1 (MONOVALENT) (UNKNOWN)) 2010 Experience Here: I am 46, Female on discharge from hospital 12.6.10 10pm after treatment for acute diverticuli

<span style='visibility: visible;'><span style='visibility: visible;'>After battling with acute insomnia for about 3 months, my GP prescribed Trimipramine 25mg. This still didn't get me much sleep, so he prescribed Purata 30mg. Better, bu

5th Week of Champix, so not smoked now for 3 weeks. Have experienced really bad headaches, mainly in the eyes, like acute sinisitus, will have to go to doctors to see if being caused by champix. Hope I do not have to come off them

Acute lower back pain causing lack of mobility?

Acute psychosis

Acutecontinuous incontinence


Citalopram caused me to suffer acute-closed angle Glaucoma CAG,

Dizziness, full body tremors, body aches, racing heart, acute changes in blood pressure

Doctor had me take amoxicillin 500mg because of sinus infection. I toke 4x500mg for 10days. It cleared up the infection but I have had acute gout attacks for over a month. my feet/hands/wrists/knees have developed terrible pain to the point that I co

Acute Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)
Condition: Acute Coronary Syndrome
Intervention: Drug: Acetylsalicylic acid (Aspirin, BAY 81-8781)
Outcome Measures: The primary efficacy variable will be the TXB2 (Thromboxane B2) concentration at 5 minutes after study drug administration.;   TXB2 (Thromboxane B2) values at 20 minutes;   Platelet aggregation inhibition;   Serum prostacyclin levels;   Incidence of post randomization deaths from all causes, cardiovascular deaths, myocardial re/infarctions and ischemic strokes;   Safety laboratory examinations, vital signs, physical examination, ECG, adverse events collection;   Incidence of all post randomization strokes of unknown etiology;   Incidence of all post randomization bleedings assessed according to the TIMI (thrombolysis in myocardial infarction) classification including hemorrhagic stroke;   Hospital mortality during the hospitalization for ACS (Acute Coronary Syndrome)
2 Recruiting Near Infrared Fluorescence Cholangiography (NIRF-C) During Cholecystectomy -- Use in Acute Cholecystitis Sub-Study
Conditions: Acute Cholecystitis;   Acute Cholangitis
Interventions: Drug: Indocyanine Green (ICG);   Device: Near Infrared Fluorescence Cholangiography (NIRF-C)
Outcome Measures: Adverse events related to use of indocyanine green (ICG);   Anatomic identification with NIRF-C and IOC;   Procedure time
3 Recruiting Clinical Characteristic of Recurrent Acute Rhinosinusitis in Children
Condition: Acute Recurrent Sinusitis
Intervention: Other: Recurrent Acute Rhinosinusitis
Outcome Measures: Presenting symptoms of recurrent Acute rhinosinusitis;   Age of onset
4 Recruiting Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome;   Adult Acute Lymphoblastic Leukemia in Remission;   Adult Acute Myeloid Leukemia in Remission;   Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Chronic Myelomonocytic Leukemia;   de Novo Myelodysplastic Syndromes;   Previously Treated Myelodysplastic Syndromes;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Refractory Anemia With Excess Blasts;   Refractory Anemia With Ringed Sideroblasts;   Refractory Cytopenia With Multilineage Dysplasia;   Secondary Acute Myeloid Leukemia;   Secondary Myelodysplastic Syndromes
Interventions: Drug: fludarabine phosphate;   Drug: cyclophosphamide;   Radiation: total-body irradiation;   Radiation: iodine I 131 monoclonal antibody BC8;   Procedure: allogeneic bone marrow transplantation;   Drug: tacrolimus;   Drug: mycophenolate mofetil;   Other: laboratory biomarker analysis
Outcome Measures: Maximum tolerated dose (MTD) of 131 I-BC8 antibody defined as the dose that is associated with a true dose limiting toxicity (DLT) rate of 25%, graded by the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 3;   Rates of immune reconstitution;   Rates of engraftment;   Rates of donor chimerism;   Rates of Acute GVHD;   Rates of disease-free survival;   Rates of disease relapse;   Disease-free survival;   Overall survival
5 Recruiting Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury
Conditions: Acute Lung Injury;   Acute Respiratory Distress Syndrome
Outcome Measures: Development of ALI;   Quality adjusted survival
6 Recruiting Phase I Study of GNKG168 in Acute Lymphoblastic Leukemia and Acute Myelogenous Leukemia
Conditions: Relapsed Acute Lymphoblastic Leukemia;   Relapsed Acute Myelogenous Leukemia
Intervention: Drug: GNKG168
Outcome Measures: Number of patients with dose limiting toxicity (DLT).;   To measure the reduction of MRD in patients treated with GNKG168.;   To measure the length or remission in patients who receive GNKG168.;   To measure the rate of Graft Versus Host Disease (GVHD) in patient with previous HSCT.;   To measure the rate graft failure in patients who previously had a HSCT and who received GNKG168.
7 Recruiting Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Conditions: Septic Shock;   Severe Sepsis;   Acute Lung Injury;   Acute Respiratory Distress Syndrome
Interventions: Drug: Placebo;   Drug: Hydrocortisone
Outcome Measures: All cause mortality;   Ventilator free day;   Vasopressor free day;   Rate of renal replacement therapy;   Organ support free days
8 Recruiting Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities;   Adult Acute Myeloid Leukemia With Del(5q);   Adult Acute Myeloid Leukemia With Inv(16)(p13;q22);   Adult Acute Myeloid Leukemia With t(15;17)(q22;q12);   Adult Acute Myeloid Leukemia With t(16;16)(p13;q22);   Adult Acute Myeloid Leukemia With t(8;21)(q22;q22);   Chronic Myelomonocytic Leukemia;   Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable;   Previously Treated Myelodysplastic Syndromes;   Recurrent Adult Acute Lymphoblastic Leukemia;   Recurrent Adult Acute Myeloid Leukemia;   Refractory Anemia With Excess Blasts;   Refractory Cytopenia With Multilineage Dysplasia;   Secondary Acute Myeloid Leukemia
Interventions: Biological: pretargeted radioimmunotherapy;   Drug: cyclosporine;   Drug: mycophenolate mofetil;   Radiation: total-body irradiation;   Procedure: nonmyeloablative allogeneic hematopoietic stem cell transplantation;   Procedure: peripheral blood stem cell transplantation;   Drug: fludarabine phosphate;   Other: pharmacological study
Outcome Measures: Incidence of dose-limiting toxicities (DLT) (Grade III/IV Bearman) to determine MTD of radiation delivered to normal organ by pretargeted 90Y-DOTA-biotin;   Rates of engraftment, chimerism, and non-relapse mortality;   Rate of grades III-IV Acute GVHD;   Achievement and duration of response
9 Recruiting Study of ABSORB Stent in Acute Myocardial Infarction
Conditions: Acute Myocardial Infarction;   Artery; Deformity, Coronary (Acquired)
Intervention: Procedure: angioplasty
Outcome Measures: MACE (Death, MI, TLR and TVR);   Acute stent Recoil
10 Recruiting Very Early veRsus Deferred Invasive Evaluation Using Computerized Tomography in Patients With Acute Coronary Syndromes
Condition: Coronary Artery Disease
Interventions: Procedure: Invasive coronary evaluation (Deferred);   Procedure: Invasive coronary evaluation (Acute)
Outcome Measures: Composite clinical endpoint;   Bleeding;   Non-bleeding, invasive procedure related complications;   Death;   Non-fatal Acute myocardial infarction;   Hospital admittance due to refractory myocardial ischemia (Acute coronary syndrome);   Repeat coronary revascularization;   Hospital admittance due to left ventricular heart failure;   GRACE Risk Score
11 Recruiting Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery
Conditions: Acute Kidney Injury;   Cardiac Surgery
Interventions: Drug: Sodium Bicarbonate;   Drug: Sodium Chloride
Outcome Measures: Acute Kidney Injury;   Duration of Acute kidney injury;   Cumulative fluid balance;   Hospital and intensive care unit length of stay;   Need for dialysis;   Incidence of Acute kidney injury according to changes in serum NGAL.;   Length of mechanical ventilation;   Change in acid-base status
12 Recruiting L-Arginine, Symmetrical and Asymmetrical Dimethylarginine (SDMA/ADMA) in Acute Kidney Injury (AKI)
Condition: Acute Kidney Injury
Outcome Measures: Difference in serum ADMA level between Acute kidney injury and renal recovery;   Difference in serum SDMA level between Acute kidney injury and renal recovery;   Associations between ADMA/SDMA serum level and all cause mortality;   Associations between ADMA/SDMA serum level and parameters of arterial stiffness;   Associations between ADMA/SDMA serum level and parameters of renal function
13 Recruiting Air Pollution, Inflammation and Acute Coronary Syndrome
Condition: Patients With Acute Coronary Syndrome
Intervention: Other: Particulate air pollutants
Outcome Measure: Impact of air pollution on inflammation, oxidative stress and 1-year prognosis in patients hospitalized for Acute coronary syndrome.
14 Recruiting Predicting Acute Kidney Injury After Coronary Artery Bypass Graft
Conditions: Coronary Artery Bypass Surgery;   Acute Kidney Injury;   Creatinine;   Mortality
Intervention: Procedure: Coronary artery bypass surgery
Outcome Measures: Acute kidney injury diagnosis defined by RIFLE criteria;   Acute kidney injury as defined by AKIN (Acute kidney injury network) criteria
15 Recruiting Modalities of Renal Replacement Therapy in Pediatric Acute Kidney Injury
Condition: Kidney Failure, Acute
Intervention: Procedure: Acute extra renal replacement therapy
Outcome Measures: extra renal replacement therapy;   Current incidence;   etiologies;   Risk factors of mortality and non recovery of the renal function
16 Not yet recruiting Early Goal Directed Therapy for Acute Kidney Injury
Condition: Kidney Injury, Acute
Intervention: Procedure: Early goal directed therapy during 6 hours after occurence of the early phase of Acute kidney injury
Outcome Measures: Observation of Acute kidney injury;   Organ failure during first 48 hours and during stay on intensive care unit;   Duration of stay on intensive care unit and in hospital;   Mortality during stay on intensive care unit
17 Recruiting China Acute Myocardial Infarction Registry
Condition: Acute Myocardial Infarction
Outcome Measures: In-hospital mortality of the patients with Acute myocardial infarction in different-level hospitals across China;   The rate of the application of thrombolysis and primary percutaneous coronary intervention for Chinese patients with Acute myocardial infarction in different-level hospitals;   provoking factors of Chinese patients with AMI across different areas and different population in China
18 Recruiting Pulmonary And Renal Support During Acute Respiratory Distress Syndrome
Conditions: Acute Respiratory Distress Syndrome;   Acute Renal Failure
Intervention: Device: Combined ECCOR and RRT
Outcome Measures: Arterial carbon dioxide reduction;   Gas transfer measurement;   Arterial blood gases;   carbon dioxide elimination (VCO2);   Respiratory mechanics and hemodynamic parameters;   Safety monitoring
19 Recruiting Echocardiography Predictive of the Inefficacy and/or of the Unsafeness of Recruitment Maneuvers in Patients With Acute Respiratory Distress Syndrome.
Condition: Acute Respiratory Distress Syndrome
Intervention: Device: Echocardiography
Outcome Measures: Efficacy and safety of recruitment maneuvers in patients with Acute Respiratory Distress Syndrome.;   Feasibility of the measurement of Longitudinal Strain and Strain Rate of the right ventricle in patients suffering from Acute Respiratory Distress Syndrome.;   Comparison of the results of echocardiographic measurements between the group CONTROL and the group FAILURE.;   Evaluate the effect of the inefficacy and/or of the unsafeness of the recruitment maneuver on the future of the patient suffering from Acute Respiratory Distress Syndrome.
20 Recruiting Acute Lymphoblastic Leukemia Registry at Asan Medical Center
Conditions: Leukemia, Acute Lymphoblastic;   Precursor B-Cell Lymphoblastic Leukemia;   Leukemia, Biphenotypic, Acute;   Leukemia, Lymphoblastic, Acute, Philadelphia-Positive;   Lymphoblastic Lymphoma
Intervention: Other: Diagnosed as ALL
Outcome Measures: Overall survival;   Event-free survival;   Relapse-free survival