Angina and Tildiem


Angina Symptoms and Causes

Angina is chest pain or discomfort you feel when there is not enough blood flow to your heart muscle. Your heart muscle needs the oxygen that the blood carries. Angina may feel like pressure or a squeezing pain in your chest. It may feel like indigestion. You may also feel pain in your shoulders, arms, neck, jaw, or back.

Angina is a symptom of coronary artery disease (CAD), the most common heart disease. CAD happens when a sticky substance called plaque builds up in the arteries that supply blood to the heart, reducing blood flow.

There are three types of Angina:

  • Stable Angina is the most common type. It happens when the heart is working harder than usual. Stable Angina has a regular pattern. Rest and medicines usually help.
  • Unstable Angina is the most dangerous. It does not follow a pattern and can happen without physical exertion. It does not go away with rest or medicine. It is a sign that you could have a heart attack soon.
  • Variant Angina is rare. It happens when you are resting. Medicines can help.

Not all chest pain or discomfort is Angina. If you have chest pain, you should see your health care provider.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for angina

angina treatment research studies

Tildiem clinical trials, surveys and public health registries

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Tildiem Side Effects

Bradycardia (22)
Musculoskeletal Stiffness (13)
Renal Failure (10)
Atrial Fibrillation (8)
Fall (5)
Malaise (5)
Renal Failure Acute (5)
Arthralgia (5)
Myalgia (4)
Blood Pressure Increased (3)
Headache (3)
Skin Exfoliation (3)
Rash Maculo-papular (3)
Overdose (3)
Nausea (3)
Liver Disorder (3)
Muscle Rigidity (3)
Loss Of Consciousness (3)
Atrioventricular Block First Degree (2)
C-reactive Protein Increased (2)
Blood Pressure Decreased (2)
Cardiac Arrest (2)
Coronary Artery Occlusion (2)
Atrioventricular Block Complete (2)
Cardio-respiratory Arrest (2)
Condition Aggravated (2)
Coronary Artery Stenosis (2)
Dehydration (2)
Dyspnoea (2)
Feeling Abnormal (2)
Syncope (2)
Sinoatrial Block (2)
Aspartate Aminotransferase Increased (2)
Intentional Overdose (2)
Toxic Skin Eruption (2)
Perivascular Dermatitis (2)
Transient Ischaemic Attack (2)
Acute Myocardial Infarction (2)
Alanine Aminotransferase Increased (2)
Traumatic Intracranial Haemorrhage (2)
Face Oedema (2)
Nephritis Interstitial (1)
Nervousness (1)
Neuropathy Peripheral (1)
Metabolic Encephalopathy (1)
Left Ventricular Failure (1)
Left Ventricular Dysfunction (1)
Lichenoid Keratosis (1)
Melaena (1)
Memory Impairment (1)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)

Recent Reviews

Hello, I am a 56 year old woman, married with 2 children. I have had this problem for the last 3 months and my husband is tired of going to the emergency room to be told they do not know what it is. I never know when it is going to hit. When it comes


I am taking mono-tildiem for the relaxation of my oespophagus because it is tight and causing reflux. I have been coughing for some time now. Is that a result of the drug? Thank you.

Tiredness and weakness

Amlodpine is a dihydropyridine group Ca channel blocker usually prescribed to controll hypertension (Males) or prinz metal angina (Females) trade names Norvasac Quvasac ..... Ca channels are universally present in our b

Diagnosed with Angina last week commenced tablets on Wednesday by Friday had nausea and on Saturday was violently sick from 9.30 a.m. to 8 p.m. Stopped tablets and felt fine. At GP's request reintroduced them yesterday now have

Extreme heartburn and abdominal pain.Even hurts to swallow salava.Strong odor when urinate.Angina ocassionally,and swelling of feet and legs.

I developed side effects while taking liothyronine June 2010.Liothyronine discontinued at that time. Five months later still experiencing angina, rapid or irregular heartbeat and fatique. Symptoms have slowly i

I have been on Nicorandil, 10mg morning and night for unstable angina, now increase to 20mg in morning and 10 at night. I am very dizzy, extreme headache. What is worse the side effects or angina. I have had 3 open heart operations with 5 grafts and

I have been taking Isosorb for 08 weeks the first two days were ok just a couple of flare ups with angina shortness of breath restricted breathing was forced to sit and relax for about 30 min each time. how ever over the next week or so the flare up

I was given Nicorandil for Unstable Angina in conjunction with beta blocker,statins and .Isosorbide,and Ramipril,Forhypertention. IDeveloped severe mouth and tongue ulcers.Tongue biopsy was norma.l Nicorandil discontinued mouth h

I was on Isisorbide and switched to Ranexa a couple of weeks ago. I have began having angina pain again and want to ask if it is Ok to go back to the isiorbide immeadiately? I beleive it is angina? I haven't had any problems for a year or so since be

I was prescribed lercanidipine for angina, I persevered with the drug although it made me feel unwell and brought on my atrial fibrillation, caused tiredness and nausea. I tried taking it at a different time of day, so that I could at least

I was taking Exforge in combination with Tekturna and Metoprolol. After a few weeks of the thumping sensation at night and angina and dizziness; I experienced what I thought was food poisoning. Severe vomiting at 2:00 am and diarrhea the next morning

Angina Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control
Conditions: Atrial Fibrillation;   Atrial Flutter
Interventions: Drug: Metoprolol;   Drug: Diltiazem
Outcome Measures: Conversion to sinus rhythm;   Heart rate control;   Home discharges from Emergency Department (ED);   Total hospital cost;   Rehospitalization for Atrial Fibrillation
2 Unknown  Low Dose of Diltiazem for Rate Control of Atrial Fibrillation
Condition: Atrial Fibrillation
Intervention: Drug: low dose diltiazem
Outcome Measure: Success rate of rate control
3 Recruiting Efficacy Study of Cardizem in Pulmonary Arterial Hypertension
Conditions: Idiopathic Pulmonary Arterial Hypertension;   Primary Pulmonary Hypertension;   Pulmonary Arterial Hypertension;   Familial Primary Pulmonary Hypertension
Interventions: Drug: Diltiazem Hydrochloride;   Drug: Sugar Pill
Outcome Measures: Six Minute Walk Distance;   Dyspnea Score;   Quality of Life Score;   Pulse Oximetry
4 Recruiting Effect of Diltiazem on Coronary Artery Ectasia
Condition: Coronary Artery Ectasia
Interventions: Drug: intracoronary administration of diltiazem;   Drug: intracoronary injection of 5 mL saline
Outcome Measures: Myocardial blush grade;   TIMI (Thrombolysis in myocardial infarction) flow grade;   TIMI (Thrombolysis in myocardial infarction) frame count
5 Unknown  A Drug Interaction Study of Boceprevir in Combination With Amlodipine or Diltiazem in Healthy Volunteers
Conditions: Hepatitis C;   Hypertension
Interventions: Drug: Amlodipine;   Drug: Diltiazem
Outcome Measures: pharmacokinetics;   number of participants with adverse events
6 Not yet recruiting Treatment Of Chronic Anal Fissure
Condition: Chronic Anal Fissure
Interventions: Other: Levorag Emulgel;   Drug: Diltiazem
Outcome Measures: Complete healing at week 12;   Complete healing at week 8;   Defecation pain at day 3;   Defecation pain at day 7;   Adverse events
7 Recruiting Regulatory T Cells in Type 1 Diabetes Patients Treated With IL-2
Condition: Type 1 Diabetes
Intervention: Drug: Aldesleukin (Proleukin)
Outcome Measures: The primary endpoint is based upon the percentage of CD4+T regulatory (defined as CD3+CD4+CD25highCD127low) cells within the CD3+CD4+T cell gate following treatment with IL-2.;   T regulatory cell phenotype and stability;   T effector cell number and phenotype;   T cell subset proliferation and populations;   Intracellular T cell and natural killer(NK) cell signalling;   T regulatory cell function;   IL-2 pathway genotype;   Lymphocyte Subsets;   Serum Cytokines;   Glycaemic control;   Number of Participants with Adverse Events as a Measure of Safety and Tolerability
8 Not yet recruiting Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation
Condition: Stable Angina
Interventions: Drug: Diltiazem treated group;   Drug: Bisoprolol treated group;   Drug: Candesartan treated group
Outcome Measures: Wall to lumen ratio of fundus vessel;   lipid parameter;   Serum markers of inflammation;   Change of nitrate need
9 Recruiting Treatment of Supine Hypertension in Autonomic Failure
Condition: Hypertension
Interventions: Drug: Clonidine;   Drug: Nitroglycerin transdermal;   Drug: Dipyridamole/ Aspirin (Aggrenox);   Drug: Desmopressin (DDAVP);   Drug: Sildenafil;   Drug: Nifedipine;   Drug: Hydralazine;   Drug: Hydrochlorothiazide;   Drug: Placebo;   Drug: Bosentan;   Drug: Diltiazem;   Drug: Eplerenone;   Drug: guanfacine;   Dietary Supplement: L-arginine;   Drug: captopril;   Drug: carbidopa;   Drug: losartan;   Drug: metoprolol tartrate;   Drug: nebivolol hydrochloride;   Drug: prazosin hydrochloride;   Drug: tamsulosin hydrochloride;   Other: Head-up tilt.;   Drug: aliskiren;   Other: Local heat stress
Outcome Measures: Decrease in supine systolic blood pressure;   Decrease in pressure natriuresis
10 Unknown  Sevoflurane Versus Intravenous Anaesthetic Agents in Morbid Obese Patients
Condition: Morbid Obesity
Interventions: Drug: Sevoflurane;   Drug: Propofol- Remifentanyl;   Drug: Propofol, Remifentanyl
Outcome Measures: Change from baseline of perioperative haemodynamic measurements (HR, MAP), recovery scores (Aldrete, White,Chung);   Drug Consumption, Drug Cost.
11 Recruiting Ranolazine and Microvascular Angina by PET in the Emergency Department
Condition: Microvascular Angina
Interventions: Drug: Ranolazine;   Drug: Placebo
Outcome Measures: Coronary Flow Reserve;   SAQ(Seattle Angina Questionnaire) Scores
12 Recruiting Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery
Condition: Heart; Dysfunction Postoperative, Cardiac Surgery
Intervention: Other: Atrial fibrillation
Outcome Measures: Freedom from any episode of post operative atrial fibrillation longer than 6 hours duration occurring during the study period.;   Telemetry monitoring strips
13 Recruiting Non Invasive Measurements of Fibrosis, Inflammation and Steatohepatitis in Morbidly Obese Patients
Conditions: Morbid Obesity;   Non Alcoholic Steatohepatitis
Outcome Measures: To validate the use of serum tests, FibroScan / CAP abdominal MRI for the diagnosis of severe steatosis and / or NASH (specificity, sensitivity, positive and negative predictive values);   Histological lesions of liver fibrosis and quantification of abdominal fat by MRI
14 Recruiting Catheter Ablation vs Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial
Conditions: Atrial Fibrillation;   Arrhythmia
Interventions: Device: Left atrial ablation;   Drug: Rate or Rhythm Control Therapy
Outcome Measures: LA catheter ablation is superior to rate or rhythm control drug therapy for decreasing the incidence of the composite endpoint of total mortality, disabling stroke, serious bleeding, or cardiac arrest in patients warranting therapy for AF.;   LA catheter ablation is superior to rate or rhythm control drug therapy for reducing total mortality;   Total mortality or cardiovascular hospitalization;   Cardiovascular death;   Cardiovascular death or disabling stroke;   Arrhythmic death or cardiac arrest;   Heart failure death;   Freedom from recurrent AF;   Cardiovascular hospitalization;   Medical costs, resource utilization, and cost effectiveness;   Quality of Life;   Composite adverse events;   Left atrial size, morphology and function and its relationship to morbidity and mortality