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Bipolar and Effexor

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Bipolar Symptoms and Causes

Bipolar disorder is a serious mental illness. People who have it go through unusual mood changes. They go from very happy, "up," and active to very sad and hopeless, "down," and inactive, and then back again. They often have normal moods in between. The up feeling is called mania. The down feeling is depression.

The causes of Bipolar disorder aren't always clear. It runs in families. Abnormal brain structure and function may also play a role.

Bipolar disorder often starts in a person's late teen or early adult years. But children and adults can have Bipolar disorder too. The illness usually lasts a lifetime.

If you think you may have it, tell your health care provider. A medical checkup can rule out other illnesses that might cause your mood changes.

If not treated, Bipolar disorder can lead to damaged relationships, poor job or school performance, and even suicide. However, there are effective treatments to control symptoms: medicine and talk therapy. A combination usually works best.

NIH: National Institute of Mental Health

Check out the latest treatments for bipolar

bipolar treatment research studies

Effexor clinical trials, surveys and public health registries


Find Drug Side Effect reports



Effexor Side Effects

Dizziness (757)
Nausea (642)
Anxiety (625)
Depression (552)
Feeling Abnormal (546)
Headache (543)
Suicidal Ideation (501)
Condition Aggravated (471)
Paraesthesia (420)
Insomnia (400)
Malaise (400)
Fatigue (339)
Crying (334)
Hyperhidrosis (312)
Confusional State (308)
Agitation (292)
Tremor (286)
Diarrhoea (284)
Asthenia (279)
Convulsion (276)
Completed Suicide (222)
Hypertension (221)
Fall (219)
Disturbance In Attention (207)
Vomiting (204)
Aggression (201)
Blood Pressure Increased (194)
Anger (193)
Withdrawal Syndrome (183)
Somnolence (180)
Pain (177)
Suicide Attempt (175)
Weight Increased (163)
Abnormal Behaviour (151)
Dyspnoea (150)
Amnesia (150)
Intentional Overdose (136)
Irritability (135)
Abnormal Dreams (123)
Tinnitus (118)
Activities Of Daily Living Impaired (117)
Serotonin Syndrome (115)
Loss Of Consciousness (111)
Panic Attack (111)
Arthralgia (110)
Nightmare (109)
Disorientation (108)
Off Label Use (106)
Overdose (106)
Emotional Disorder (105)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

10 years on effexor, weight gain of 20 lbs last 5 years when increased to 300mg., no change in cal or exercise, since getting older realized needed fewre calories so tried to reduce like always could wirhWW and exercise, no success, couldn'

Effexor & Pristiq is poison - I would know, I started taking it at 16 yrs old, instead of counselling I was given Effexor by a 'psychiatrist drug dealer' I was never offered counselling. I spent of $25,000 on this medication in my lifetime. D

Effexor raised my blood presure alot ,I had extreme painful headaches,rash that started on my face which was horrible,then spread to my chest,my neck was beat red I itched so badly.I think docotrs need to be more educated on this med before giveing i

Effexor was horrible for me...as soon as I started it I started having panic attacks worse than ever (supposed to help them) scary bad dreams, waking up in a sweat and not knowing who I was, then depression. The first day I expeirenced the panic atta

Ever since i've been prescribed effexor, my systolic bp measurement is high. is there a correlation between the two.

Had effexor yesterday 75 mg not again nusea,blurred vision and today the worst longest headache I have ever had,GP didn't even check my BP before prescription.I am recovering from a fractured skull think I will deal with my depression without drugs

Headaches BAD and very sleepy and increased anxiety

Hi.. I have been on effexor. I stopped 'cold turkey'. I know this is wrong. I have gained 25 pounds in the past year. I have increasingly became more depressed. I can't sleep. I have strong thoughts of wanting to die. I don't want to kill myself, but

Hi.. actually i have cyclothymia bipolar.. i just started using lithium 3 weeks ago... when do i start to feel a loooot better? thnx

Hi...Im not sure how active this forum is I am sitting here after my latest episode of a non-diagnosed illness fueled by substance abuse. I have spent the last 10 years crumbling and rebuilding my life only to have the same thing happen over and

Abilify for BiPolar Disorder, how does it work for you?

Acording to your list most of my meds combined with my diagnosis with bipolar can cause this and it is also true with alternative meds. The only question that remains is are there any combination of drus that I'm on can seriously complicate it and be

After taking the medication for two weeks I experience a severe allergic reaction to the medication. My side effects were paranoia hallucinations, anxiety, delusions, and psychosis. Due to the medication I was diagnosed bipolar.

Hi.. actually i have cyclothymia bipolar.. i just started using lithium 3 weeks ago... when do i start to feel a loooot better? thnx

I am a 41 year old female diagnosed with BiPolar 2 at age 19. Over the years I have been on several types of anti depressants including prothieden, ciprimil andzoloft. I have been taking Lovan off and on (mostly on) for

I am a 42yr. oldwoman who was prescribed Revia for alcoholic relapse. I am also bipolar and take Welbutrin (150mg) & Lamictal (100mg). I experience the side effects of an intense sensationsof needing to stretch - like when you wake

I am on a bunch of meds, for bipolar, so I have muscle movement or twitches. So when I was on the Geodon it really helped me with my pyschosis, but it made twitch a whole lot more. And one of the risk is TD. I heard drin

I am taking Zyprexor for my bipolar condition. After taking Chaampix for a week I suddenly experienced a total memory loss of most of the important information I had gained over the last couple of months including my new address, telephone number, wh

I guess my main concern is, since I've read how TriNessa affects the emotions of other women, how will this affect my Bipolar type II Disorder? This is where I have more depressive episodes and rarely have manic episodes. I take Citalopram (Celexa -

I have been taking trilipix for 2 weeks and have been getting more depressed I don't see depression as a side effect so I'm not sure whats going on but its the only new med thats been added and my bipolar symptons are and have been in check so it ha

Bipolar Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Repetitive Transcranial Magnetic Stimulation Compared or Associated With Venlafaxine for Depressive Disorder
Condition: Depression
Interventions: Other: active rTMS and active Venlafaxine;   Other: active rTMS and sham Venlafaxine;   Other: sham rTMS and active Venlafaxine
Outcome Measures: The primary outcome measure is remission;   fMRI;   CGI;   QIDS-C30;   UKU Scale
2 Recruiting Venlafaxine PK Following Bariatric Surgery
Conditions: Roux en Y Gastric Bypass;   Sleeve Gastrectomy
Intervention: Drug: Venlafaxine IR and Venlafaxine XR
Outcome Measures: Venlafaxine Plasma Concentrations/Area-Under-the-Curve (AUC);   Secondary PK Characteristics (Composite)
3 Recruiting Study to Examine the Effect of Gastric Bypass Surgery on Venlafaxine ER Blood Levels
Conditions: Bariatric Surgery;   Gastric Bypass;   Roux-en-Y Gastric Bypass
Intervention: Drug: venlafaxine ER (extended-release) 75 mg
Outcome Measure: Venlafaxine levels pre- and post-gastric bypass
4 Recruiting ADAPT: Addressing Depression and Pain Together
Conditions: Depression;   Back Pain
Interventions: Other: Combination Treatment with Higher-dose venlafaxine + PST-DP;   Drug: Higher-dose venlafaxine and supportive management
Outcome Measures: Depression: Patient Health Questionnaire-9;   Pain: 20-Point Numeric Rating Scale;   Self-Efficacy: Chronic Pain Self-Efficacy Scale
5 Recruiting Quality of Life Study Using Gabapentin Versus Venlafaxine in Treating Hot Flashes in Patients With Prostate Cancer
Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin;   Drug: Venlafaxine
Outcome Measures: Changes in quality of life;   compare toxicity rates between the gabapentin and venlafaxine treatment groups;   Assess changes in the hot flash scores for the two arms;   Assess changes in quality of life using the Hot flash related Daily Interference Scale (HFRDIS)
6 Recruiting Effectiveness Study to Compare Venlafaxine With Fluoxetine in the Treatment of Postmenopausal Women With Major Depression
Condition: Major Depression
Intervention: Drug: venlafaxine,fluoxetine
Outcome Measures: change of 24-item Hamilton Rating Scale for Depression total score;   the mean change of HAMD-24 subscale score in items 10, 11, 12, 13 (anxiety and somatizations) at endpoint
7 Recruiting Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks
Condition: Major Depressive Disorder
Interventions: Drug: ketamine venlafaxine;   Drug: Venlafaxine
Outcome Measure: Depressive state
8 Recruiting The HELP PAIN Trial
Condition: Neck Pain
Intervention: Drug: Venlafaxine
Outcome Measures: Average neck pain;   Chronic neck pain
9 Recruiting Venlafaxine for Depression in Alzheimer's Disease (DIADs-3)
Conditions: Alzheimer's Disease;   Depression
Interventions: Drug: Placebo;   Drug: Venlafaxine
Outcome Measures: 225 mg daily dose of venlafaxine over 12 weeks will produce changes in response on the modified AD Cooperative Study-Clinical Global Impression of Change and the Cornell Scale for Depression in Dementia.;   Examine in a proof of concept, 12-week randomized controlled trial, the safety of venlafaxine at a target dose of 225 mg daily for the treatment of Depression in patients with AD.
10 Not yet recruiting Beta-arrestins and Response to Venlafaxine in Major Depressive Disorder (MDD) (DEPARRESTCLIN)
Conditions: Major Depressive Disorder;   Major Depressive Episode
Intervention: Drug: Venlafaxine extended release
Outcome Measure: Change from baseline in depressive symptoms on the Hamilton Depression Rating Scale-17 items
11 Recruiting Venlafaxine Augmentation in Treatment Resistant Depression
Condition: Depression
Interventions: Drug: Venlafaxine;   Drug: Quetiapine
Outcome Measures: Hamilton Depression Rating Scale (HDRS);   Self reported psychopathology (Beck Depression Inventory [BDI], State-Trait Anxiety Inventory [STAI]);   Cognitive function
12 Unknown  Hippocampal Volume in Young Patients With Major Depression Before and After Combined Antidepressive Therapy
Condition: Depressive Disorder, Major
Interventions: Drug: Mirtazapine;   Drug: Venlafaxine
Outcome Measures: Categorial response to the medication. Categorial response is defined on the basis of CGI Improvement scale and 50% reduction in MADR-S score;   Tolerability of treatment as assessed using the DOTES scale;   Cognitive deficits as judged by the SKT system;   Self assessment of depression and anxiety using Beck's Depression/Anxiety Inventory (BDI/BAI);   Changes is blood levels of homocysteine, folate, vit B12, P11
13 Unknown  Pharmacogenomics Studies of Antidepressants
Conditions: Major Depressive Disorder;   Antidepressive Agents;   Pharmacogenetics;   Venlafaxine;   Fluoxetine
Interventions: Drug: Venlafaxine;   Drug: Fluoxetine
Outcome Measures: Hamilton Depression Rating Scale (HDRS);   C-reactive Protein and IL-6;   fasting blood glucose, lipid profiles
14 Recruiting International Study to Predict Optimised Treatment - in Depression
Condition: Major Depressive Disorder
Interventions: Drug: Escitalopram;   Drug: Sertraline;   Drug: Venlafaxine XR
Outcome Measures: To determine whether the genetic-brain-cognition function markers (or combination of markers) 'normalise' with acute drug treatment in MDD;   To determine whether markers of acute treatment prediction are also predictive of functional outcome over 6-12 months.
15 Recruiting A Study of Sustained-Release Desvenlafaxine Hydrochloride for the Treatment of Major Depressive Disorder
Condition: Major Depressive Disorder
Interventions: Drug: Sustained-Release Desvenlafaxine Hydrochloride;   Drug: Sustained-Release Venlafaxine Hydrochloride
Outcome Measures: Change From Baseline on the Hamilton Rating Scale for Depression, 17-item Total Score (HAM-D17);   Change From Baseline on the Clinical Global Impression Scale;   Change From Baseline in Clinical Global Impression-Improvement (CGI-I) Scale;   Change From Baseline in Sheehan Disability Scale (SDS) Total Score at Week 10;   Change From Baseline in Adjusted Mean on Montgomery-Asberg Depression Rating Scale (MADRS);   Change From Baseline on the Visual Analogue Scale-Pain Intensity (VAS-PI);   Number of Participants in Remission Based on the HAM-D17 at Week 10
16 Unknown  Treatment of Mild to Moderate Depression Symptoms in Patients With Spinal Cord Injury
Condition: Spinal Cord Injury
Interventions: Drug: Venlafaxine HCI;   Other: Placebo
Outcome Measures: The Patient Health Questionnaire-9 (PHQ-9);   The Beck Scale for Suicide Ideation (BSS);   16 item Quick Inventory of Depressive Symptomatology (QIDS- SR16);   The SCI Pain Instrument (SCIPI);   The Adherence and Side Effects Checklist;   CAGE & Drug Use;   Generalized Anxiety Disorder-7 (GAD-7);   The Perceived Stress Scale (PSS);   Life Experiences Survey - Disability (LES-D);   The Received Social Support and Social Undermining Scale (RSS/SU);   Measure of the Quality of the Environment;   The Perceived Handicap Questionnaire (PHQ);   Craig Handicap Assessment and Reporting Form - Short Form (CHART-SF);   The SF-12 Health Status Questionnaire - 12
17 Unknown  Electroencephalography (EEG) Signal Processing
Condition: Major Depressive Disorder
Interventions: Drug: Venlafaxine;   Drug: bupropion;   Drug: escitalopram;   Other: Psychotherapy;   Drug: Duloxetine
Outcome Measure: Machine learning
18 Recruiting Efficacy of Repetitive Transcranial Magnetic Stimulation in the Prevention of Relapse of Depression
Condition: Depression
Interventions: Procedure: repetitive Transcranial Magnetic Stimulation (rTMS);   Behavioral: counseling
Outcome Measures: Time for relapse;   Hamilton Depression Rating Scale;   Illness severity change;   subject functioning
19 Recruiting Prolonging Remission in Depressed Elderly (PRIDE)
Condition: Depression
Interventions: Drug: lithium and Venlafaxine;   Procedure: ECT
Outcome Measures: Long-term antidepressant efficacy (Hamilton Rating Scale for Depression);   Level of functioning (SF-36);   Tolerability (Mini Mental State Examination [MMSE]);   Tolerability (California Verbal Learning Test [CVLT-II], Autobiographical Memory Interview-Short Form [AMI-SF]);   Tolerability (Trail Making Tests, DRS-IP and Delis-Kaplan Executive Function System, Verbal Fluency;   Safety (Udvalg for Kliniske Undersogelser [UKU] Side Effects Rating Scale)
20 Recruiting Predict Antidepressant Responsiveness Using Pharmacogenomics
Conditions: Depression;   Depressive Symptoms
Interventions: Drug: SSRI class antidepressant;   Drug: non-SSRI class antidepressant
Outcome Measure: Presences of each individual symptom of depression at 1,2,4,6,12 weeks