Bone and Acyclovir


Bone Symptoms and Causes

Your Bones help you move, give you shape and support your body. They are living tissues that rebuild constantly throughout your life. During childhood and your teens, your body adds new Bone faster than it removes old Bone. After about age 20, you can lose Bone faster than you make Bone. To have strong Bones when you are young, and to prevent Bone loss when you are older, you need to get enough calcium, vitamin D, and exercise. You should also avoid smoking and drinking too much alcohol.

Bone diseases can make Bones easy to break. Different kinds of Bone problems include

  • Low Bone density and osteoporosis, which make your Bones weak and more likely to break
  • Osteogenesis imperfecta makes your Bones brittle
  • Paget's disease of Bone makes them weak
  • Bones can also develop cancer and infections
  • Other Bone diseases, which are caused by poor nutrition, genetics, or problems with the rate of Bone growth or rebuilding

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

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Acyclovir clinical trials, surveys and public health registries

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Acyclovir Side Effects

Renal Failure Acute (111)
Nausea (55)
Confusional State (53)
Neurotoxicity (52)
Blood Creatinine Increased (51)
Pyrexia (48)
Hallucination, Visual (38)
Herpes Zoster (38)
Vomiting (37)
Pain (37)
Fatigue (36)
Somnolence (36)
Renal Failure (35)
Diarrhoea (34)
Agitation (31)
Rash (31)
Renal Impairment (30)
Dyspnoea (30)
Haemodialysis (28)
Neutropenia (28)
Malaise (27)
Encephalopathy (27)
Febrile Neutropenia (27)
Dysarthria (26)
Hallucination (26)
Platelet Count Decreased (26)
Nephropathy Toxic (26)
Back Pain (24)
Alanine Aminotransferase Increased (23)
Insomnia (23)
Abdominal Pain (23)
Headache (22)
White Blood Cell Count Decreased (22)
Aphasia (22)
Pruritus (21)
Disorientation (20)
Hypertension (19)
Dizziness (19)
Pancytopenia (19)
Abdominal Pain Upper (19)
Coma (19)
Paraesthesia (19)
Pneumonia (18)
Sepsis (18)
Blood Pressure Increased (18)
Hepatotoxicity (17)
Anaemia (17)
Ataxia (17)
Hypotension (17)
Multi-organ Failure (17)

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Recent Reviews

After my second revision surgury in 2004 my SMITH AND NEPHEW GENESIS II femoal component came lose to the <a href='mailto:poijim.wehner@yahoo.comnt'>poijim.wehner@yahoo.comnt</a> I had to have my third revision surgery.

Can grafts from cadaver cause immune deceases like Lupus on the transplant patient?

Going to hospital for a bone graft to my ankle they are going to take the bone from my hip. how long will i be in hospital,

Hey plz help m an aircraft maintenance technician. i met a serious accident before 2yrs in which my right hand was broken. in bangalore doctor did the wrong operation due to this my right hand got infected and ostiomylities occur. in my native again

Hi I wont to ask about treartment of bone fragmentation &amp; how much period of time it take to return to normal in adult

Hi, I had neck surgery 6 months a go and approx. a month ago I start using the bone growth stimulator, I felt really sick after meaning a lot of headaches, neck and shoulder pain, didn't think it was related but I stopped using it for a week because

I am curious to know if you had extreme fatigue. I am about a month out from my triple cervical fusion and I just started it 3 days ago. I use it four hours a day and I can not stay awake after using it. It is ridiculous...I am not even taking my

I had a bone graft in my lunate bone 6 weeks ago, they used cadaver bone. I want to find out how long it takes for the occasional pains to go away? I get them shooting down from my left ring finger past my wrist and lots of burning pains. My cast co

I had a Neck operation they used two cadaver bones ever since the operation i have had so much pains in my arms legs and feet it waks me up and im rh negative too but my question is my red platlets been clumping now my red cells are low is this a re

I had bone fusion surgery over a month ago and post operatively was placed on spinalogic bone growth stimulator every twenty four hours at 30 minute intervals. I never had a blood pressure problem in my life, even after the first week of surgery when

When I press down on my stomach, in the lower right side in the pelvic region it hurts. Right by my hip bone. This has been going on for about a week. Could this be really bad? Im scared that I could be pregnant. but i dont think

<span style='color: #808080;'><b>i was given a flu shot on 11/18/10 the medical asst did the injection higher than i have ever had in the past. she injected right on the bone. the pain i have is horrible. i had an exray. (no foreign body)

After 10 days of taking Aclasta serum 5mg i had all the side effects and after 10 days i still have chills and bone pain, what should i do? By the way im having a blood test tomorrow to know about the kidney,liver and glucose. so what should i do??

After 2 and half months of taking boniva i devoped severe shoulder pain that cause tendonitis and bursitis and abnormal bone formation and will have to have surgery now to inprove my pain i have been in severe pain for 5 months now boniva side eff

After the first gardisil shot i started getting a redish brown line following my hip bone then it spread to my upper stomach, just solid around the abdominal area. After i got a small itchy red dot on my back and about a month later it turned into a

Age 58, stage 1 breast cancer a year ago. double mastecomy, by choice. chemo...started aromasin in October 2008. had a bone denstity test in September 2008 and started fosamax.... had another bone denstity test in April 2009 and before the results

Am sorry if my english is bad::::::: my mother hadlymphoma in bone marrors docter give mabthera 600mg is that good for him

Arimidex caused untold joint, bone pain, sleeplessness. Switched to Aromasin,more of the same....talked at length with my Dr. and considering the cancer I had, and the quality of life I now have....I'll risk the posibility without the drugs.

Been diaginosed with this disorderfor 10 months now. have ongioing outbreaks within 1 week off stop taking prednisone. just been diaginosed with humerous bone infarct. have stopped taking predinsone for last 4weeks and have been h

Bone pain, stomach pain, muscle pain, hip and joint pain, rectal sphincter pain, quit taking August 2009, still having pain as of May 2010

Bone Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases
Conditions: Cancer;   Bone Metastases
Interventions: Device: F-18 PET Bone scan;   Device: Tc-99m Bone scan
Outcome Measures: Accurate identification of Bone metastases;   Change in clinical management;   Determine if F-18 PET Bone scans lead to fewer follow-up imaging studies.;   Quantify any adverse events from either type of scan.;   Perform subgroup analyses according to cancer cell type.
2 Recruiting Parallel Study Between BMP-2 and Autologous Bone Graft After Ilizarow Treatment
Conditions: Bone Degenerative Changes;   Osteoarthritis;   Degenerative Disorder of Bone
Interventions: Drug: Bone Morphogenetic Protein 2;   Procedure: Autologous Bone graft
Outcome Measures: Visible radiological signs of healing after 6 months.;   Change in serologic Bone markers
3 Recruiting Interest of Bone Substitute Material in Immediate Complete Denture
Conditions: Alveolar Bone Loss;   Denture Complete Immediate;   Bone Substitute;   Replacement Material;   Bone
Interventions: Device: Conventional protocol;   Device: Bone substitute material group
Outcome Measures: Comparison of Bone ridge height one year after maxillary immediate complete denture placement with or without Bone substitute material in incisive-canine sockets;   Height and width average between day 10th and day 90th after maxillary immediate complete denture placement, and between day 10th and one year
4 Recruiting Prospective Evaluation of Anorganic Bovine Bone Mineral Versus Calcium Phosphosilicate Alloplastic Bone Putty in Direct Sinus Augmentation: a Spilt-mouth Study
Conditions: Sinus Floor Augmentation;   Maxillary Sinus
Interventions: Procedure: Calcium phosphosilicate alloplastic Bone putty in direct sinus augmentation;   Procedure: Anorganic bovine Bone mineral in direct sinus augmentation
Outcome Measures: Percentage of new Bone growth in the maxillary sinus;   Gain in vertical Bone height;   Radiographic Bone density;   Primary implant stability;   Marginal Bone level maintenance
5 Recruiting Monitoring of Bone Free Flaps With Microdialysis
Conditions: Microsurgery;   Head and Neck Reconstructive Surgery;   Head and Neck Cancer;   Head and/or Neck Shotgun Trauma;   Bone Free Flap
Intervention: Device: CMA 70 catheter directly positioned in Bone tissue
Outcome Measures: Feasibility study of monitoring Bone free flaps with microdialysis (catheter directly positioned in Bone tissue);   Evaluation of "flush-out" period;   Compliance of the prescription
6 Recruiting A Migration and Bone Density Study Comparing Hi-Fatigue Bone Cement and Palacos Bone Cement
Condition: Hip Arthritis
Interventions: Device: Hi-Fatigue Bone Cement;   Device: Palacos Bone Cement
Outcome Measure: Femoral component migration (roentgen stereo photogrammetric analysis - RSA)
7 Recruiting F18PET/CT Versus TC-MDP Scanning to Detect Bone Mets
Condition: Bone Metastases
Intervention: Device: Bone Scan: F18-Fluoride PET/CT or TC-MDP
Outcome Measure: Analysis of the diagnostic performance of [18F]NaF fluoride PET/CT scanning
8 Unknown  Use of Adult Bone Marrow Mononuclear Cells in Patients With Long Bone Nonunion
Condition: Long Bone Nonunion
Intervention: Procedure: Osteosynthesis
Outcome Measures: Absence of adverse effects during timeframe as infections or complications related with the intervention;   Improvement and union of the Bone
9 Recruiting Bone Mineral Density Changes of the Acetabulum After Revision Hip Arthroplasty Using Bone Impaction Grafting
Conditions: Disorder of Bone Density and Structure, Unspecified;   Satisfaction
Interventions: Radiation: DEXA: dual energy X-ray absorptiometry;   Other: Short Form Health Survey 12;   Other: VAS-satisfaction;   Other: VAS-pain;   Other: Harris Hip Score
Outcome Measure: Bone mineral density changes
10 Recruiting Effect of Risedronate on Bone Morbidity in Fibrous Dysplasia of Bone
Condition: Fibrous Dysplasia of Bone
Interventions: Drug: risedronate;   Drug: placebo
Outcome Measures: Intensity of Bone pain, assessed by visual analogical scale ranging from 0 to 10, on the most painful site.;   Surface of osteolytic lesions at three years. Radiological improvement.;   Variation of biochemical markers of Bone turnover at three years;   Number of painful sites;   Improvement in quality of life;   Variation in Bone mineral density of the femoral neck at three years
11 Recruiting A Comparison of Bone Formation With Three Different Bone Graft Materials Following Sinus Graft
Condition: Inadequate Bone Height in Maxillary Posterior Area
Interventions: Procedure: Sinus augmentation;   Drug: Equimatrix;   Drug: OSSIF-i sem;   Drug: Bio-oss
Outcome Measures: A histomorphometric measurement of the percentage of vital Bone in a total amount of Bone.;   A histomorphometric measurement of the percentage of non-vital Bone and connective tissue.
12 Recruiting Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute
Condition: Bone Neoplasm
Interventions: Device: Bioactive glass;   Device: Beta-tricalcium phosphate (ChronOs);   Procedure: Autograft;   Procedure: Allograft (frozen femoral head)
Outcome Measures: Stratum I: Hand-grip strength test;   Stratum II: Healing of cortical Bone window based on CT scan evaluation;   Biomaterial incorporation assessed with radiographs;   Pain intensity (VAS);   Stratum I: DASH-questionnaire;   RAND-36;   Surgical wound healing;   Soft tissue complications;   Bone complications
13 Recruiting Outcome Comparison of Allograft and Synthetic Bone Substitute in High Tibial Osteotomy
Condition: Osteoarthritis, Knee
Interventions: Procedure: Allogenic Bone graft;   Procedure: Synthetic Bone substitute (geneX®)
Outcome Measures: Temporal change of postoperative pain;   Pre&postoperative Hemoglobin level;   Total operation time;   Temporal change of weight bearing status;   Temporal change of pain with weight bearing;   Amount of drainage;   Working time for Bone defect filling;   Temporal progression of Bone healing on X-rays
14 Recruiting Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Techniques for the Treatment of Large Long Bone Defects
Condition: Segmental Long Bone Defects
Interventions: Procedure: Iliac crest autogenous Bone grafting;   Procedure: Reamer-Irrigator-Aspirator autogenous Bone grafting
Outcome Measures: Defect Healing;   Functional outcomes
15 Not yet recruiting rhBMP-2 vs Autologous Bone Grafting for the Treatment of Non-union of the Docking Site in Tibial Bone Transport
Conditions: Bone Healing;   Bone Morphogenetic Proteins;   Bone Transport
Intervention: Device: rhBMP-2
Outcome Measures: Bone healing in the docking site;   Infection;   Edema;   cancer
16 Recruiting Bone Quality and Quantity Following Guided Bone Regeneration Prior to Dental Implant Placement
Condition: Resorbed Alveolar Ridge Prior to Dental Implant Insertion
Interventions: Device: Bio-Oss (by Geistlich);   Device: BondBone (by Augma)
Outcome Measures: Volume of the new Bone formed after a GBR procedure;   Bone quality
17 Recruiting Focused Ultrasound Surgery in the Treatment of Pain Resulting From Metastatic Bone Tumors With the ExAblate 2100 Conformal Bone System
Conditions: Bone Cancer;   Bone Metastases;   Pain
Intervention: Device: ExAblate 2100
Outcome Measures: Safety;   Efficacy;   Effectiveness
18 Unknown  Mother Daughter Bone Microarchitecture
Condition: Bone Fragility
Interventions: Radiation: HRpQCT;   Biological: Sampling;   Radiation: Bone absorptiometry
Outcome Measures: Role of Bone microarchitecture in the hereditary determinism of Bone fragility;   Role of Bone mineral density in the hereditary determinism of Bone fragility;   Role of Bone turnover and hormones in the hereditary determinism of Bone fragility
19 Not yet recruiting 18F-NaF PET Imaging for Bone Scintigraphy
Condition: Bone Metastases From Breast or Prostate Cancer
Interventions: Procedure: NaF PET/CT Imaging;   Procedure: 99mTc-medronate whole body Bone scan with SPECT;   Drug: 18F-NaF (185-370 MBq)
Outcome Measures: Accuracy, sensitivity, and specificity of 18F-Sodium Fluoride (18F-NaF) Positron Emission Tomography compared to 99mTc-Methylene Diphosphonate (MDP) Bone SPECT imaging for detection of Bone metastasis.;   The secondary outcome is to monitor the short-term side-effects following 18F-NaF PET/CT to assess for adverse drug reactions
20 Recruiting Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft
Condition: Bone Augmentation
Intervention: Device: Ridge preservation using DFDBA
Outcome Measures: percent new vital Bone formation;   change in ridge width and ridge height