Chest and Isosorbide


Chest Symptoms and Causes

Having a pain in your Chest can be scary. It does not always mean that you are having a heart attack. There can be many other causes, including

  • Other heart problems, such as angina
  • Panic attacks
  • Digestive problems, such as heartburn or esophagus disorders
  • Sore muscles
  • Lung diseases, such as pneumonia, pleurisy, or pulmonary embolism
  • Costochondritis - an inflammation of joints in your Chest

Some of these problems can be serious. Get immediate medical care if you have Chest pain that does not go away, crushing pain or pressure in the Chest, or Chest pain along with nausea, sweating, dizziness or shortness of breath. Treatment depends on the cause of the pain.

Check out the latest treatments for chest

chest treatment research studies

Isosorbide clinical trials, surveys and public health registries

Find Drug Side Effect reports

Isosorbide Side Effects

Product Quality Issue (279)
Dizziness (135)
Chest Pain (85)
Hypotension (80)
Headache (71)
Fall (69)
Dyspnoea (65)
Myocardial Infarction (65)
Asthenia (64)
Blood Pressure Decreased (52)
Syncope (49)
Loss Of Consciousness (42)
Nausea (34)
Diarrhoea (29)
Fatigue (29)
Renal Failure Acute (28)
Vomiting (28)
Incorrect Dose Administered (28)
Cardiac Failure (28)
Cardiac Failure Congestive (27)
Angina Pectoris (26)
Cerebrovascular Accident (25)
Heart Rate Increased (25)
Cardiac Disorder (23)
Cardiac Arrest (23)
Malaise (23)
Myocardial Ischaemia (23)
Condition Aggravated (22)
Arrhythmia (21)
Coronary Artery Disease (20)
Chest Discomfort (20)
Bradycardia (19)
Pain (19)
Renal Failure (19)
Palpitations (19)
Silent Myocardial Infarction (18)
Pneumonia (18)
Pain In Extremity (17)
Completed Suicide (16)
Heart Rate Decreased (16)
Gait Disturbance (16)
Arthralgia (15)
Anxiety (15)
Atrial Fibrillation (15)
Hypertension (15)
Death (15)
Orthostatic Hypotension (15)
Muscle Spasms (15)
Rash (14)
Somnolence (14)

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Common Meds

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Cipro (8580)
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Crestor (18839)
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Effexor (7289)
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Flomax (2177)
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Medrol (650)
Mirena (41254)
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Morphine (5356)
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Recent Reviews

When lying down, become chest congested and must get rid of mucous. No or little problem during day. Is this common? does any one else have this. Should I be scared?

Can someone telll me can a person die with chest pain/heart disesaes

Hello i have a really bad chest pain every time i breath in been going on for months now i just thought it could be indigestion but now getting worse and is now affetcing my roght arm what could it be?

Hi Debbie, We have the same symptoms. I don't know what is this. Did you already figure out what is the problem with you? Thank you.

Hi i went yesterday to Er had chest pain on right side cant lift my right arm up with times.I had 2 weeks ago very bad flue.They did ecg was normal.Wake up this morning with severe burning chest pain cant breath in or out. Just not feeling well.

Hi there I would like some info on chest pain or a phone number where I can book to see Acupuncture. Thank you for your time

Hi: My symptoms started about two weeks ago with one day of severe diarrhea. Since then I have been having severe chest pain along with symptoms of feeling so dizzy that I cannot even do anything. The pain is so bad that it causes dizziness and ligh

I also have several chest pain, heart burn and vomitting issue and other disorders in my stomach. I'm not really sure what's going on, i've been to different kinds of meds and alternative including natural food alternatives. However still the chest p

I am having chest pains that feel tightness and burning on my left side and my left leg,left side of my neck hurts too,what can I do to get relieve from the pain,I tried an muscle relaxer and asprin but those didn't help me?what can u do to help me?

I dont know but i started having pain on my left side above my left breast,it really doesnt hurt bad i just know its there.and it does feel strange.thanks joe

After using Clobetasol for a two week cycle, my doctor suggested I use it one day during the week, applying it twice that day. Since that time, I have experinced severe chest pain. I recently saw my doctor for heart attack symptoms before I reali

After the second day taking Lekoklar XL chest pains started and have not let up (I am on 4th day of medication). My cough has gotten better but temperature is still up and am feeling weaker now than ever.

I am real tired I've been on coreg about two weeks, I don't know if Ican keep taking it. I am so sleepy all the time don't want to do anything my chest hurts. Don't know what to do, if Idon't take it my heart want work right. JUST STUCK

When I eat or drink this burning feeling in my chest going up like I am about vomiting.what is happening? And something I and chest pain too! And I am 14 and a girl

Emotional Anxciety then chest pain, jaw pain on left side and headaches, I am not taking it no more. there has to be something else less tramatising to my system. It was bad enugh that i was at work when the emotional anxiety hit. not cool at all.

Intersting on the Bicor . i have been on it since march this year , starting with 2.5 , then to 5.0 , 7.5 and 10mg for the last 3 months . always felt tired in the increse dosage as advised . but now have had a fe w joint aches , chest pains and cur

>:o Took my first dose today,it left me covered in a red itchy rash on neck,chest,back and sides within 10 minutes of consuming.This product is now sitting in the trash can. :(

When lying down, become chest congested and must get rid of mucous. No or little problem during day. Is this common? does any one else have this. Should I be scared?

one 10 mg pill cuased presure in thechest bad muslespasms in the back think past doses has sent me skizzo

syptoms nausea, sweating dilated pupils unable to sleep, fever, tight chest,high white blood cells, high levels of creatine phosphokinase and myoglobin. what the hell is worng with me?

Chest Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma
Conditions: Trauma;   Flail Chest;   Rib Fractures;   Surgery
Interventions: Drug: NSAID;   Drug: Opioids;   Drug: Thoracic Epidural anaesthesia;   Drug: Paracetamol;   Procedure: Surgical management
Outcome Measures: Respiratory insufficiency;   Hospital stay
2 Unknown  LUCAS Chest Compressor Versus Manual Chest Compression in Out-of-hospital Sudden Cardiac Arrest. LUCAT Trial
Condition: Sudden Cardiac Arrest
Interventions: Device: LUCAS (Lund University Cardiac Assist Sysrem);   Other: Manual Chest compressions
Outcome Measures: Survival at hospital admittance;   Survival on discharge from hospital (or 30 days if not applicable) in acceptable neurological state (CPC scale 1 or 2);   Restoration of spontaneous circulation;   EndTidal CO2 values;   SOFA scale values;   Days before discharge from Intensive Care Unit (ICU) / Coronary Care Unit (CCU);   Metabolic (pH, lactate) and inflamatory (leukocytes, C reactive protein) parameters;   Epidemiology of Out-of-Hospital Cardiac Arrest;   To obtain a blood sample for genetic and biological studies;   Left ventricular function
3 Recruiting Treatment of Acute, Unstable Chest Wall Injuries
Conditions: Blunt Injury of Thorax;   Flail Chest;   Chest Wall Injury Trauma;   Rib Fracture
Intervention: Procedure: Surgical fixation
Outcome Measures: Ventilator-free days (VFD);   Number of days in the Intensive Care Unit (ICU);   Amount of pain medication administration, converted to oral morphine equivalence;   Rate of Pneumonia;   Pulmonary function assessment;   Rate of return to work;   assessment of functional health and well being
4 Unknown  Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection
Conditions: Lung Diseases, Interstitial;   Pulmonary Nodule, Solitary
Interventions: Procedure: Do not leave a Chest tube in the pleural cavity.;   Procedure: Do leave a Chest tube in the pleural cavity.
Outcome Measures: Pneumothorax >10% / Hemothorax;   Pain (Visual analogue scale);   Surgical procedure duration;   Hospital stay
5 Recruiting KatGuide Method Versus Conventional Method at Insertion of Chest Tube
Conditions: Pneumothorax;   Hydrothorax;   Hemothorax;   Empyema;   Chylothorax
Interventions: Device: KatGuide versus conventional method (forceps);   Procedure: Chest tube insertion
Outcome Measures: Chest tube placement;   Length of hospital stay;   Time with Chest tube;   Infection in wound;   Number of Chest tubes
6 Recruiting Home Hypnotherapy for Refractory Functional Chest Pain: A Pilot Study
Condition: Functional Chest Pain
Interventions: Behavioral: Home Hypnotherapy;   Behavioral: Educational
Outcome Measures: Global change in Chest pain at the 12 week mark.;   Global change in Chest pain at the 4-6 week and 3 month follow-up marks, as well as change in symptom, psychometric, and HRQOL scores at each assessment
7 Recruiting Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)
Condition: Thoracic Aortic Aneurysms
Intervention: Device: Talent Thoracic Stent Graft System
Outcome Measure: Freedom from aneurysm-related mortality at 5 years
8 Recruiting Shared Decision Making in the Emergency Department: Chest Pain Choice Trial
Conditions: Chest Pain;   Acute Coronary Syndrome
Intervention: Other: Chest Pain Choice Decision Aid
Outcome Measures: Test if Chest Pain Choice safely improves validated patient-centered outcome measures.;   Test if the decision aid has an effect on healthcare utilization within 30 days after enrollment.;   Test if the decision aid safely improves additional validated patient outcome measures.
9 Recruiting Valiant Thoracic Stent Graft With the Captivia Delivery System in the Treatment of Descending Thoracic Aortic Diseases (VALIANT CAPTIVIA France)
Conditions: Aortic Aneurysm, Thoracic;   Descending Thoracic Aortic Dissection;   Penetrating Ulcer;   Aorta Thoracic; Traumatic Rupture;   Aortic Diseases
Intervention: Device: DTA patients (Valiant)
Outcome Measures: All-cause mortality;   Exclusion of aneurysm, penetrating aortic ulcer (PAU), false lumen or rupture site;   Major Adverse Events;   Conversion to open repair;   Endovascular or surgical secondary procedures;   Adverse device effects;   Thoracic disease-related mortality
10 Recruiting Objective and Subjective Outcomes of an Electronic Chest Drainage System
Condition: Lung Cancer
Intervention: Device: electronic Chest drainage system
Outcome Measures: Duration of Chest tubes;   total distance of ambulation in the first 48 postoperative hours
11 Recruiting Improving Search Strategy for Identifying Urgent Conditions on the Chest X-ray
Condition: Using Expert Visual Search Strategy to Train Students to Read the Chest X-ray
Interventions: Other: training in visual search strategy;   Other: access to a library of Chest x-rays without search strategy
Outcome Measure: Improvement in medical student's visual search strategy at reading a Chest x-ray
12 Not yet recruiting Chest Physiotherapy and Lung Function in Primary Ciliary Dyskinesia
Condition: Primary Ciliary Dyskinesia
Intervention: Procedure: Chest physiotherapy
Outcome Measures: Difference in FEV1 before and after treatment;   Difference in LCI before and after Chest physiotherapy
13 Recruiting Early Aggressive Pain Management is Associated With Improved Outcomes in Blunt Thoracic Trauma
Conditions: Thoracic Injury;   Rib Fracture;   Sternal Fracture
Outcome Measure: Hospital Length of stay
14 Unknown  The First Therapeutic Intervention in Malignant Pleural Effusion Trial
Conditions: Malignant Pleural Effusion;   Pleural Effusion
Interventions: Other: Large bore Chest drain + NSAID based analgesic regimen;   Other: Small bore Chest drain + NSAID based analgesic regimen;   Other: Large bore Chest drain + opiate based analgesic regimen;   Other: Small bore Chest drain + opiate based analgesic regimen
Outcome Measures: An average pain score over 72 hours post pleurodesis for malignant pleural effusion;   Pleurodesis success at 3 months post randomization (time to relapse of pleural effusion);   Presence of chronic Chest pain on the side of the pleurodesis
15 Not yet recruiting Chest Physiotherapy Technique Increasing Inspiratory Flow on Weaning From Non Invasive Ventilation
Conditions: Neonatal Respiratory Distress Syndrome;   Intubation, Intratracheal
Interventions: Procedure: Chest physiotherapy;   Procedure: Usual surveillance
Outcome Measures: Number of days of non invasive respiratory support post extubation;   Duration of oxygen dependence.;   Duration of hospitalisation of the premature infant on the special care unit;   bronchopulmonary dysplasia as established by the WALSH test as well as the presence of atelectasis on the Chest X ray done within the 7 days following extubation;   Pain score realised during the session
16 Recruiting Evaluation of the Lung Nodule Sensitivity of Stationary Chest Tomosynthesis in Patients With Known Lung Nodules
Condition: Signs and Symptoms
Intervention: Device: Stationary Digital Chest Tomosynthesis
Outcome Measures: Specificity (percentage);   Specificity of s-DCT (percentage);   Reader preference (arbitrary units)_
17 Recruiting Pre-Operative Assessment of Chest Wall Invasion in NSCLC Using Pre-Operative, Surgeon Performed Ultrasound
Condition: Non Small Cell Lung Cancer
Intervention: Procedure: Transthoracic Ultrasound
Outcome Measure: The primary outcome will be the accuracy of real-time Chest ultrasonographic in assessing Chest wall invasion compared to Ultrasound
18 Not yet recruiting Effect of Thoracic Paravertebral Block on Heart Rate Variability (HRV)
Conditions: Breast Surgery;   Thoracic Paravertebral Block;   HRV;   Autonomic Nervous System
Interventions: Other: Left thoracic paravertebral block;   Other: Right thoracic paravertebral block
Outcome Measure: Effect of thoracic paravertebral block on Heart Rate Variability (HRV)
19 Recruiting Thoracic Spine Manipulation for Patients With Thoracic Spine Pain
Condition: Pain
Intervention: Other: Manipulation of thoracic spine compared to sham TNS treatment
Outcome Measures: Thoracic spine pain (Visual analogue scale);   Thoracic spine mobility (computer controllod spine PA measurement, tape measurements, inclinometer)
20 Unknown  Coronary CT Angiography in Acute Chest Pain is a Cost Effective Risk Stratification Strategy
Condition: Acute Chest Pain
Intervention: Procedure: Coronary CT Angiogram
Outcome Measures: Determine if the cumulative costs over 90-days of providing treatment services are reduced when adding coronary CTA to the standard-of-care (CTA + SOC) in patients with acute Chest pain compared to SOC alone.;   Determine if the rate of hospitalizations, nuclear perfusion scans and interventional cardiac catheterizations will be reduced by adding the coronary CTA to the SOC (CTA + SOC) compared to the SOC alone.;   Compare the rate of death, myocardial infarct (MI), acute coronary syndrome (ACS), and recidivism to the ED over 90-days when adding coronary CTA to the SOC (CTA + SOC) in ED patients with acute Chest pain compared to the SOC alone group.