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Migraine and Thyroid

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Migraine Symptoms and Causes

What are Migraines?

Migraines are a recurring type of headache. They cause moderate to severe pain that is throbbing or pulsing. The pain is often on one side of your head. You may also have other symptoms, such as nausea and weakness. You may be sensitive to light and sound.

What causes Migraines?

Researchers believe that Migraine has a genetic cause. There are also a number of factors that can trigger a Migraine, including

  • Stress
  • Anxiety
  • Hormonal changes in women
  • Bright or flashing lights
  • Loud noises
  • Strong smells
  • Medicines
  • Too much or not enough sleep
  • Sudden changes in weather or environment
  • Overexertion (too much physical activity)
  • Tobacco
  • Caffeine or caffeine withdrawal
  • Skipped meals
  • Medication overuse (taking medicine for Migraines too often)
  • Certain foods and food additives such as
    • Alcohol
    • Chocolate
    • Aged cheeses
    • Monosodium glutamate (MSG)
    • Some fruits and nuts
    • Fermented or pickled goods
    • Yeast
    • Cured or processed meats
Who is at risk for Migraines?

About 12 percent of Americans get Migraines. They can affect anyone, but you are more likely to have them if you

  • Are a woman. Women are three times more likely than men to get Migraines.
  • Have a family history of Migraines. Most people with Migraines have family members who have Migraines.
  • Have other medical conditions, such as depression, anxiety, bipolar disorder, sleep disorders, and epilepsy.
What are the symptoms of Migraines?

There are four different phases of Migraines. You may not always go through every phase each time you have a Migraine.

  • Prodome. This phase starts up to 24 hours before you get the Migraine. You have early signs and symptoms, such as food cravings, unexplained mood changes, uncontrollable yawning, fluid retention, and increased urination.
  • Aura. If you have this phase, you might see flashing or bright lights or zig-zag lines. You may have muscle weakness or feel like you are being touched or grabbed. An aura can happen just before or during a Migraine.
  • Headache. A Migraine usually starts gradually and then becomes more severe. It typically causes throbbing or pulsing pain, which is often on one side of your head. But sometimes you can have a Migraine without a headache. Other Migraine symptoms may include
    • Increased sensitivity to light, noise, and odors
    • Nausea and vomiting
    • Worsened pain when you move, cough, or sneeze
  • Postdrome (following the headache). You may feel exhausted, weak, and confused after a Migraine. This can last up to a day.

Migraines are more common in the morning; people often wake up with them. Some people have Migraines at predictable times, such as before menstruation or on weekends following a stressful week of work.

How are Migraines diagnosed?

To make a diagnosis, your health care provider will

  • Take your medical history
  • Ask about your symptoms
  • Do a physical and neurological exam

An important part of diagnosing Migraines is to rule out other medical conditions which could be causing the symptoms. So you may also have blood tests, an MRI or CT scan, or other tests.

How are Migraines treated?

There is no cure for Migraines. Treatment focuses on relieving symptoms and preventing additional attacks.

There are different types of medicines to relieve symptoms. They include triptan drugs, ergotamine drugs, and pain relievers. The sooner you take the medicine, the more effective it is.

There are also other things you can do to feel better:

  • Resting with your eyes closed in a quiet, darkened room
  • Placing a cool cloth or ice pack on your forehead
  • Drinking fluids

There are some lifestyle changes you can make to prevent Migraines:

  • Stress management strategies, such as exercise, relaxation techniques, and biofeedback, may reduce the number and severity of Migraines. Biofeedback uses electronic devices to teach you to control certain body functions, such as your heartbeat, blood pressure, and muscle tension.
  • Make a log of what seems to trigger your Migraines. You can learn what you need to avoid, such as certain foods and medicines. It also help you figure out what you should do, such as establishing a consistent sleep schedule and eating regular meals.
  • Hormone therapy may help some women whose Migraines seem to be linked to their menstrual cycle
  • If you have obesity, losing weight may also be helpful

If you have frequent or severe Migraines, you may need to take medicines to prevent further attacks. Talk with your health care provider about which drug would be right for you.

Certain natural treatments, such as riboflavin (vitamin B2) and coenzyme Q10, may help prevent Migraines. If your magnesium level is low, you can try taking magnesium. There is also an herb, butterbur, which some people take to prevent Migraines. But butterbur may not be safe for long-term use. Always check with your health care provider before taking any supplements.

NIH: National Institute of Neurological Disorders and Stroke

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Product Formulation Issue (23)
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Recent Reviews

Hello, over the past one or two years i have been suffering from VERY bad miagrains. I have been to my docter about it however he says quote ' its like finding a needle in a hay stack to narrow it down to what could be wrong' therefore i would real

I am told I have miagraines I feel my ead is going to explode feel very sick but am not light sensitive can it still be miagraine. I can not walk as in to much pain and noise really affects me!! this is the first time its happened and am a fit 20 ye

I have been getting these little blister sores that bust and turn into scap little sores. I have noticed it since about a month or so after found out my thyroid is not working right. Could this be a side effect from the medication

I have only been on it five days, it is better than nothing so far. My own thyroid production took a downfall and I am used to Armour Thyroid which has been my doctor's first choice for years. I was told by my European Doctor that Synthyroid is jus

I'm losing a lot of weight. Was 110 when started on Armour. Lost 15 lbs in one year. Take 90

In the Spring of 2008 I went to my PCP for allergy symptoms, and when he felt my neck glands to make sure that I didn't have something similiar to strept throat, he said that's the biggest Thyrioid I've ever felt, well 2 weeks later the surgeon was r

My husbadn is almost 52, and he has been very ill with a chronic GI condition for the last 12 months. He has been in and out of the hospital and had his gull bladder and appendix removed. They still have no diagnosis for the GI problems. Now last wee

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Since starting levothyroxine (11 days) I have had two migraines and three occular migraines. I'm thinking I should get off the medication and suffer with being cold.

When i used to cry i got migrain aatack nd this is often takes place is dis normal ?

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Is it effective for cases of migraine

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At first I just felt tired for about 5 hours, then horrible flu like symptoms. Pain, migraine headache, fever, muscle aches, general feeling of pain and discomfort and fever, worsening of colitis symptoms. It was a horrible experience. I had to deba

Been on symbicort for three weeks, experiencing headaches and today have migraine, also leg (calf) cramps. for last two days have been having what feels like bronchospasms. Interestingly symptoms have worsened since increasing dose frequency under Dr

Did panandeine can use for migraine??? can get it at pharmacy??

Migraine Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Thyroid Hormone Dose Adjustment in Pregnancy
Conditions: Pregnancy;   Hypothyroidism
Interventions: Drug: Anticipatory dose increase of levothyroxine;   Drug: levothyroxine
Outcome Measures: proportion of patients in each treatment arm euthyroid through gestation;   the proportion of patients in each arm who required, and the gestation week at which, levothyroxine dose adjustments (either increased or decreased) occurred to maintain a euthyroid state;   Determination of the necessary frequency of serum evaluation of TSH during the first half of gestation.
2 Recruiting Study of Optimal Replacement of Thyroxine in the Elderly
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Participant's acceptability of study design and willingness to enter study;   Participant recruitment rate;   Time to achieve desired TSH levels;   Medication compliance;   The acceptability of three patient completed questionnaires;   Assessment of mobility;   Change in specific cardiovascular risk factors;   Measure of risk of falls
3 Recruiting Study of Dose Adjustment From Levothyroxine to a New Levothyroxine Sodium Test Formulation.
Condition: Hypothyroidism
Intervention: Drug: Levothyroxine sodium new formulation
Outcome Measures: The proportion of patients that do not need a change of dose.;   The magnitude of the change in daily dose needed.;   Proportion of patients that obtained a thyroid stimulating hormone between 0.4-2.5 mU/L;   Change from baseline serum thyroid stimulating hormone (in mIU/L and percentage).
4 Unknown  Thyroxin Treatment in Sub Clinical Hypothyroidism, on the Apnea Hypopnea Index Score, Lipids and Highly Sensitive CRP
Condition: Dyslipidemia
Interventions: Drug: levothyroxine;   Drug: sugar pill
Outcome Measures: Effect of the treatment of subclinical hypothyroidism on the apnea hypopnea index (AHI) score.;   Effect of the treatment of subclinical hypothyroidism on the lipid profile in patient with dyslipidemia and on hs-CRP
5 Recruiting Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: Rate of First CVD Events, CVD Mortality and All-cause Mortality;   Change in Serum Lipid Levels;   Change in Thickness of Blood Vessel Wall;   Change in Oxidative Stress and Chronic Inflammatory Factors Associated with Atherosclerosis
6 Recruiting Desiccated Thyroid Extract and Levothyroxine for Hypothyroidism Treatment
Condition: Primary Hypothyroidism.
Interventions: Drug: Levothyroxine;   Drug: Desiccated thyroid extract
Outcome Measures: thyroid-symptom questionnaire;   Wechsler Memory Scale-Version IV (WMS-IV);   Biochemical measures
7 Recruiting Thyroid Hormone Replacement for Subclinical Hypothyroidism
Condition: Subclinical Hypothyroidism
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measures: Fatal and non-fatal cardiovascular events;   Thyroid-specific quality of life;   Health-related quality of life;   Handgrip strength;   Executive cognitive function;   Total mortality;   Basic Activities of Daily Living;   Extended activities of daily living;   Haemoglobin
8 Recruiting Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Conditions: Down Syndrome;   Subclinical Hypothyroidism
Intervention: Drug: Levothyroxine
Outcome Measures: Change in non-HDL cholesterol from baseline at 6, 12 and 18 months.;   Change in quality of life from baseline at 6, 12 and 18 months.
9 Recruiting L-Thyroxine Supplementation for Preterm Newborns Less Than 32 Weeks of Gestation With Hypothyroxinemia
Condition: Hypothyroxinemia
Interventions: Drug: L-Thyroxine;   Drug: water
Outcome Measures: Neurodevelopmental outcome;   Morbidity associated with management of newborns < 32 WG with hypothyroxinemia
10 Recruiting Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism
Conditions: Hypothyroidism;   Thyroid Diseases;   Endocrine System Diseases
Intervention: Drug: L-thyroxine
Outcome Measures: change in lipid profile;   change in thickness of blood vessel wall;   change in endothelial function;   change of adipocytokines;   Change of Oxidative Stress and Chronic Inflammatory Factors Related with Atherosclerosis
11 Recruiting Thyroid Study Type 2 Diabetes Mellitus (T2DM)
Conditions: Diabetes;   Hypothyroidism
Intervention: Drug: Euthyrox (levothyroxine)
Outcome Measures: Thyroid hormone-induced change in whole body insulin sensitivity (change in insulin-stimulated glucose disposal) and muscle mitochondrial function;   Thyroid hormone-induced change of lipid content in skeletal muscle and liver and brown adipose tissue activity
12 Recruiting Early Levothyroxine Post Radioactive Iodine
Condition: Graves' Disease
Intervention: Drug: Levothyroxine
Outcome Measures: Prevention of overt hypothyroidism;   Quality of Life
13 Recruiting Antithyroid Drug Treatment of Thyrotoxicosis in Young People
Condition: Paediatric Thyrotoxicosis
Interventions: Procedure: Block and Replace;   Procedure: Dose Titration;   Drug: carbimazole;   Drug: propylthiouracil;   Drug: thyroxine
Outcome Measures: Remission rate as defined by patients who are biochemically euthyroid at the end of the 6 year study period.;   Biochemical control as reflected by blood TSH and thyroxine levels;   The frequency of adverse events on the 2 treatment regimens.
14 Recruiting The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma
Conditions: Thyroid Carcinoma;   Hypothyroidism
Interventions: Other: Black Coffee;   Other: Coffee with Milk;   Other: Black Tea;   Other: Water
Outcome Measures: Change in TSH (thyrotropin-stimulating-hormone) with each beverage type;   Change in TSH with various beverages;   Change in total T4 with each beverage type;   Change in free T4 with each beverage type;   Change in total T3 with each beverage type
15 Not yet recruiting Thyroid Hormones Treatment in Asthma Exacerbation
Condition: Asthma
Interventions: Drug: IV thyroxin;   Drug: Placebo
Outcome Measures: time to normalization of PEF (peak expiratory flow);   Length of stay;   Time to oxygenation;   heart rate;   respiratory rate
16 Recruiting Selenium Supplementation in Pregnancy
Conditions: Pregnancy;   Infertility;   Auto-immune Thyroiditis
Interventions: Dietary Supplement: Selenium;   Other: Sugar Pill Placebo;   Other: Selenium + L-Thyroxine (LT4);   Other: Sugar Pill Placebo + L-Thyroxine (LT4)
Outcome Measures: Changes in TPOab and/or Tgab;   Changes in thyroid volume and echogenicity;   Changes in thyroid hormones (TSH, FT4, FT3);   Evaluation of Maternal risks;   Evaluation of Infant risks;   Changes in of quality of life;   Evaluation of Health Services:;   Changes in the selenium-dependent antioxidant enzyme glutathione peroxidase;   Changes in implantation and pregnancy rates
17 Recruiting The TRUST Study - Depression Substudy
Conditions: Subclinical Hypothyroidism;   Depression
Interventions: Drug: Levothyroxine;   Drug: Placebo
Outcome Measure: Change from baseline in 15-items Geriatric Depression Scale
18 Recruiting Preconceptional Thyroid Screening and Childhood Nerocognitive Function
Condition: Hypothyroidism
Intervention: Procedure: levothyroxine
Outcome Measures: Offspring neurocognitive assessment at 0-3 yrs;   Offspring IQ assessment at 0-3 yrs;   Incidence of neonatal hypothyroid and complications
19 Unknown  The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children
Conditions: Child Development Disorders;   Pregnancy;   Subclinical Hypothyroidism
Intervention:
Outcome Measure:
20 Recruiting Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children
Condition: Down Syndrome
Intervention: Drug: thyroid hormone and folinic acid
Outcome Measures: GMDS ( Griffiths Mental Development Scale);   BL (Brunet Lezine revised scale)