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Muscle and Flexeril

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Muscle Symptoms and Causes

Your Muscles help you move and help your body work. Different types of Muscles have different jobs. There are many problems that can affect Muscles. Muscle disorders can cause weakness, pain or even paralysis.

Causes of Muscle disorders include

  • Injury or overuse, such as sprains or strains, cramps or tendinitis
  • A genetic disorder, such as muscular dystrophy
  • Some cancers
  • Inflammation, such as myositis
  • Diseases of nerves that affect Muscles
  • Infections
  • Certain medicines

Sometimes the cause is not known.

Check out the latest treatments for muscle

muscle treatment research studies

Flexeril clinical trials, surveys and public health registries


Find Drug Side Effect reports



Flexeril Side Effects

Pain (103)
Pulmonary Embolism (74)
Fatigue (71)
Nausea (70)
Fall (68)
Pain In Extremity (66)
Dyspnoea (66)
Oedema Peripheral (65)
Feeling Abnormal (65)
Depression (65)
Somnolence (64)
Headache (64)
Muscle Spasms (64)
Overdose (63)
Dizziness (61)
Deep Vein Thrombosis (54)
Anxiety (50)
Convulsion (48)
Confusional State (46)
Asthenia (44)
Back Pain (13)
Loss Of Consciousness (11)
Hypertension (11)
Heart Rate Increased (11)
Abdominal Pain Upper (10)
Amnesia (10)
Malaise (10)
Injury (10)
Blood Pressure Increased (10)
Cerebrovascular Accident (9)
Cardiac Failure (9)
Death (9)
Injection Site Pain (9)
Weight Increased (9)
Pneumonia (9)
Lethargy (9)
Diarrhoea (8)
Completed Suicide (8)
Muscular Weakness (8)
Urinary Tract Infection (8)
Vision Blurred (8)
Vomiting (8)
Incorrect Dose Administered (7)
Hallucination (7)
Liver Disorder (7)
Hypotension (7)
Paraesthesia (7)
Suicidal Ideation (7)
Rhabdomyolysis (7)
Myocardial Infarction (7)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)
Zoloft(6792)
Zyrtec(1669)

Recent Reviews

Anxiety, anger, and exhaustion

Calf twitches

Calfs constly twitching

I broke my back as a child (I am now 32) and have had two back surgeries and I have been visiting doctors my whole life. I rarely take any medications but I recently had a severe set back. My job requires me to travel and work frequently. My back d

I have a problem with the muscles right under my eye twitching, then the whole eyelid twitching, even winking sometimes, and spasms where my lower legs will just jump all of a sudden.

I have been taking Metoprolol tar 25mg for the past six year my muscles have been hurting. If I set for a while its hard for me to get up and get moving. But Im in constant pain daily. It's been eight month since I stop taking them and im s

I have muscle twiching all over. Legs, arms, thighs, ankel, back and butt

I just had my first shots of xolair 2wks ago. within the first few days I had some spasms in the right side of my back. i also exoerienced spasms in my left hand within those same few days. since then my left eye has been twitching every day.

I was admitted to hospital with a suspected blood clot on my lung left side, i was getting bad pains there and dizzyness ,when i got to hospital they put me on oxygen coz it was reel low in a blood test then started injecting me in the stomac was kle

I was taking Flexeril after I was diagnosed with a rib contusion following heavy lifting. I am taking Lexapro, Adderall and Trazadone already for A.D.D. depression and sleep deprivation. The Flexeril made me extremely tired, irrit

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

muscle cramping when in a dead sleep

I just had the infusion two days ago (1/19/10) and was surprised with the intensity of muscle pain the day after the treatment. My pain was localized to my rib cage, neck, shoulders and upper back. In addition I was very fatiqued...slept most of

I started taking this medicine geodon 40 mg once a day. Then i notice i was blinking a lot. Then i started having eye muscle spasms several times a day.Now i have to go to the eye dr.I stop taking the medicine. Til I see what the dr.says.

I was having frequent leg cramps. They worked their way from my foot up to my thigh. I just thought it was from stopping the use of muscle relaxers ( for a serious back and neck problem). I had forgotten about them and never mentioned it to either

I am having cramps, muscle pain, memory loss, I have been on Revlmid for about 1 year. Does anybody else my age have this disease, I am only 46 yr woman.

<b>Describe Your Pravastatin Experience Here:</b> I have been on 20 mg since Jan. And have been having muscle pain in the back of the thighs? Has anyone felt muscle pain in that area. Don't know if it is from medication or exercise

I received an injection close to my shoulder blade June 16, 2010. Three months later, I have an indentation and my health care provider has indicated that perhaps the muscle has scare tissue and the indentation and disc

I have been taking Ezetrol for 6 months without any side effects but now i have developed muscle pain in my right leg and my skin is very itchy. I have also reported pains in the stomach and under my right side ribs but she said

<strong></strong><span style='color: #ffa500;'>I am experiencing severe muscular <span style='color: #0000ff;'>pain/muscle tighteningin the diaphragm and sometimes &

Muscle Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Muscle Injury Prevention & Rehabilitation in Military Personnel
Condition: Muscle Injury
Interventions: Procedure: Healthy Muscle Group;   Procedure: Stretch-Contract Pre-rehabilitation Group;   Procedure: Stretch-Contract Control Group;   Procedure: Muscle Atrophy
Outcome Measures: Change from Baseline in T2 relaxation time of skeletal Muscle in the lower leg;   Change from Baseline in Creatine Kinase levels;   Change from Baseline in Muscle water proton T2;   Change from Baseline in Muscle contractile area;   Change from Baseline in Isometric Muscle strength of the ankle dorsiflexors;   Change from Baseline in Pain scores on a visual analog scale;   Change from Baseline in ankle Range of Motion (ROM)
2 Unknown  The Effects of the Inspiratory Muscle Plus Aerobic Training Compare to Aerobic Training Alone in Heart Failure Patients.
Condition: Heart Failure
Intervention: Other: Inspiratory Muscle added by aerobic to aerobic alone
Outcome Measures: To compare effects of inspiratory Muscle training added by aerobic training to aerobic training alone in heart failure patients with inspiratory Muscle weakness.;   To compare effects between the training groups evaluating strength and endurance of inspiratory Muscles; functional capacity; the physical and psychological perceptions of quality of life and heart rate variability and sleep apnea.
3 Recruiting Musculoskeletal Ultrasound Study in Critical Care: Longitudinal Evaluation
Conditions: Critical Illness;   Septic Shock;   Trauma;   Organ Failure
Intervention:
Outcome Measure: Cross sectional area of Rectus Femoris
4 Unknown  Inspiratory Muscle Training in Patients Receiving Allogenic Stem Cell Transplantation
Conditions: Inspiratory Muscle Training;   Stem Cell Transplantation;   Respiratory Muscle Training
Interventions: Procedure: Inspiratory Muscle Training;   Other: inspiratory Muscle training
Outcome Measures: Change of PI max-value from baseline at 30 days after stem cell transplantation;   Change of MVV-value from baseline at 30 days after transplantation;   inpatient days;   Incidence of pneumonia
5 Recruiting Endomysial Fibrosis, Muscular Inflammatory Response and Calcium Homeostasis Dysfunction in Duchenne Muscular Dystrophy
Condition: Duchenne Muscular Distrophy (DMD)
Intervention: Other: Muscle biopsy
Outcome Measures: Quantification of endomysial fibrosis;   quantification of the Muscle inflammation
6 Recruiting Effects of Inspiratory Muscle Training on Dyspnea Perception During Exercise in Patients With COPD
Conditions: COPD;   Severe Systemic Illness-induced Respiratory Muscle Wasting
Interventions: Device: Inspiratory Muscle Strength Training;   Device: Inspiratory Muscle Endurance Training
Outcome Measures: Dyspnea (Borg CR-10 scale);   Maximal inspiratory pressure (Pi,max);   Inspiratory Muscle Endurance during a constant load breathing task;   Endurance capacity during a constant load cycling exercise test;   Pulmonary Function;   Daily Physical Activity;   Health related Quality of Life
7 Recruiting Respiratory Muscle Training in Subacute Stroke Patients
Condition: Muscle Weakness
Interventions: Other: Inspiratory Muscle Training (IMT);   Other: High-intensity IMT
Outcome Measures: Respiratory Muscle strength;   Handgrip strength assessment;   Lower limb strength measurement;   Serum aminoacids analysis;   Adverse events as a measure of safety and tolerability
8 Recruiting Congenital Muscle Disease Study of Patient and Family Reported Medical Information
Conditions: Muscular Dystrophy;   Congenital Muscular Dystrophy;   Fukutin-related Protein Gene;   Limb Girdle;   FKRP Gene;   Childhood Onset LGMD;   Adult Onset LGMD;   POMT1;   POMT2;   POMGnT1;   LARGE;   Alpha Dystroglycan;   Dystroglycanopathy;   Centronuclear;   Multiminicore;   Multicore;   Minicore;   Congenital Fiber Type Disproportion;   Myotubular;   Nemaline;   Congenital Myopathy;   Neuromuscular;   Rigid Spine;   Phenotype-Genotype Correlation;   Cough Assisted Device;   Neuromuscular Disease;   Respiratory Exacerbation;   Invasive Ventilation;   Chest Physiotherapy;   Congenital Myopathies;   Genetic Mutations;   Hypertrophic Cardiomyopathy;   Wheelchair Use;   Cataract;   Opthalmoplegia;   Ullrich Congenital Muscular Dystrophy;   Intermediate Collagen VI Myopathy;   Laminin Alpha 2 Related Congenital Muscular Dystrophy;   MDC1A;   Merosin Deficient Congenital Muscular Dystrophy;   Congenital Muscular Dystrophy Undiagnosed;   Congenital Muscular Dystrophy Merosin Positive;   Walker Warburg Syndrome;   Muscle Eye Brain Disease;   Fukuyama;   Integrin Alpha 7 Deficiency;   Integrin Alpha 9 Deficiency;   Laminopathy;   Lamin AC;   SEPN 1 Related Myopathies;   Bethlem Myopathy;   Dystroglycanopathies;   LGMD2K;   LGMD2I;   LGMD2L;   LGMD2N;   Actin Aggregation Myopathy;   Cap Disease;   Central Core Disease;   Centronuclear Myopathy;   Core Rod Myopathy;   Hyaline Body Myopathy;   Multiminicore Myopathy;   Myotubular Myopathy;   Nemaline Myopathy;   Tubular Aggregate Myopathy;   Zebra Body Disease Myopathy;   Congenital Myopathy Other;   Reducing Body Myopathy;   Sarcotubular Myopathy;   Spheroid Body Myopathy
Intervention:
Outcome Measure:
9 Recruiting Effects of Inspiratory Muscle Training After Lung Cancer Surgery, a Randomized Controlled Trial
Conditions: Lung Cancer;   Surgery
Interventions: Other: Inspiratory Muscle training;   Other: Placebo comparator: standard physiotherapy
Outcome Measures: Change in inspiratory Muscle strength;   Change in expiratory Muscle strength;   Incidence of postoperative pulmonary complications
10 Recruiting Muscular Electrostimulation of the Sedated and Mechanically Ventilated Critically Ill Patient. Analysis of the Effect on Acquired Muscular Weakness and Its Clinical Consequences.
Condition: Polyneuropathy
Intervention: Procedure: Muscular electrostimulation and percutaneus muscular biopsy.
Outcome Measures: muscular weakness;   time of weaning
11 Recruiting Trial Study of the Efficacy of Intensive Preoperative Pelvic Floor Muscle Training to Decrease Post-prostatectomy Urinary Incontinence
Condition: Urinary Incontinence
Interventions: Behavioral: Pelvic floor Muscle training 3 weeks before radical prostatectomy;   Behavioral: Intensive preoperative pelvic floor Muscle training
Outcome Measures: Change in grams of urine loss at different intervals post surgery;   Change in patients' sense of self control in urination and quality of life at different intervals post surgery
12 Recruiting Transforming Growth Factor Beta Signalling in the Development of Muscle Weakness in Pulmonary Arterial Hypertension
Conditions: Muscle Weakness;   Pulmonary Arterial Hypertension
Intervention:
Outcome Measures: Plasma growth and differentiation factor 15 levels in participants with and without Muscle wasting;   Correlation of plasma Growth and differentiation factor 15 levels with Muscle strength;   Change in fibre type in Muscle biopsy;   GDF-15 levels in biopsy specimens;   Correlation of plasma Growth and differentiation factor 15 levels with brain natriuretic protein levels;   Correlation of plasma Growth and differentiation factor 15 levels with fat free mass index;   Correlation of plasma Growth and differentiation factor 15 levels with quality of life;   Correlation of plasma Growth and differentiation factor 15 levels with exercise tolerance;   Correlation of plasma Growth and differentiation factor levels 15 with physical activity levels;   Correlation of plasma Growth and differentiation factor levels 15 with echocardiographic measures of severity of pulmonary hypertension;   Correlation of GDF-15 levels in biopsy specimens with Muscle wasting and weakness;   Determine the contribution of atrophy and autophagy to Muscle wasting in PAH;   Determine the contribution of SMAD and non-SMAD signalling pathways to the development of Muscle weakness and wasting in PAH
13 Recruiting Muscle Training Induced Angiogenesis in COPD
Conditions: Peripheral Muscle Dysfunction;   COPD
Interventions: Procedure: Muscular biopsy;   Other: 5-10 weeks sport training
Outcome Measures: Capillary-o-fiber ratio assessed by immunochemistry on a Muscle biopsy of the vastus lateralis of the quadriceps;   quadriceps endurance;   mitochondrial density;   Muscle citrate synthase activity
14 Unknown  Effects Antioxidants Supplementation on Muscular Function Patients Facioscapulohumeral Dystrophy (FSHD)
Condition: Facioscapulohumeral Muscular Dystrophy
Interventions: Procedure: Taking of blood;   Dietary Supplement: needle biopsy of the vastus lateralis Muscle;   Dietary Supplement: Vit C Vit E Zn Se;   Dietary Supplement: Placebo Vit E Placebo Vit C Zn Se
Outcome Measures: Improvement of Muscle effort tolerance after antioxidant supplementation;   Changes in inflammatory and oxidative stress parameters after antioxidant supplementation;   Changes in muscular function after antioxidant supplementation
15 Recruiting Low Level Laser Therapy in Muscle Fatigue and Muscle Recovery
Conditions: Muscle; Fatigue, Heart;   Skeletal Muscle Recovery
Intervention: Device: Low Level Laser (LLL)
Outcome Measures: Exercise performance (MVC and peak torque);   Blood tests (composite measures)
16 Recruiting Effect of Different Electric Muscle Stimulation in Patients With Severe Sepsis and Respiratory Failure
Conditions: Severe Sepsis;   Acute Respiratory Failure;   Muscle Hypotonia;   Inflammation;   Weakness
Intervention: Device: EMS
Outcome Measures: ventilator-dependant days;   Muscle strength improvement
17 Recruiting Muscle Ultrasound Signifies Condition Upgrade Leading Approach to Recovery
Conditions: Acute Respiratory Failure;   Critical Illness
Intervention: Procedure: Ultrasound
Outcome Measure: Days of Hospitalization
18 Recruiting Whole Body Vibration Therapy in Boys With Duchenne Muscular Dystrophy
Condition: Duchenne Muscular Dystrophy
Intervention: Device: Whole Body Vibration Therapy
Outcome Measures: Assess the safety of using whole body vibration therapy in boys with Duchenne muscular dystrophy. To assess whether whole body vibration therapy can improve Muscle strength and prolong ambulation from baseline to 8 weeks of therapy. To asses.;   Does WBVT result in any change in Muscle strength.;   Does WBVT result in any Muscle function change.;   Does WBVT result in any measurable change in Muscle endurance.;   Quality of life changes.;   Gait changes.;   Bone health
19 Recruiting Measurement of the Distribution of Optical Properties in Adult Human Muscle
Conditions: Muscle Weakness Conditions;   Cachexia;   Hypothermia;   Vascular Occlusion
Intervention: Device: Diffuse Optical Spectroscopy
Outcome Measure: Measurement of the Distribution of Optical Properties in Adult Human Muscle
20 Recruiting Effects of Inspiratory Muscle Training in COPD
Conditions: COPD;   Inspiratory Muscle Weakness
Intervention: Procedure: Inspiratory Muscle Training
Outcome Measure: 6-Minute Walking Distance