Nerve and Oxycontin


Nerve Symptoms and Causes

The brain, spinal cord, and Nerves make up the nervous system. Together they control all the workings of the body. When something goes wrong with a part of your nervous system, you can have trouble moving, speaking, swallowing, breathing, or learning. You can also have problems with your memory, senses, or mood.

There are more than 600 neurologic diseases. Major types include

  • Diseases caused by faulty genes, such as Huntington's disease and muscular dystrophy
  • Problems with the way the nervous system develops, such as spina bifida
  • Degenerative diseases, where Nerve cells are damaged or die, such as Parkinson's disease and Alzheimer's disease
  • Diseases of the blood vessels that supply the brain, such as stroke
  • Injuries to the spinal cord and brain
  • Seizure disorders, such as epilepsy
  • Cancer, such as brain tumors
  • infections, such as meningitis

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nerve treatment research studies

Oxycontin clinical trials, surveys and public health registries

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Oxycontin Side Effects

Anxiety (606)
Pain (554)
Depression (486)
Nausea (432)
Overdose (409)
Constipation (367)
Back Pain (360)
Death (321)
Arthralgia (314)
Vomiting (309)
Substance Abuse (306)
Headache (292)
Asthenia (278)
Diarrhoea (272)
Inadequate Analgesia (270)
Abdominal Pain Upper (251)
Abdominal Pain (238)
Polysubstance Abuse (233)
Coma (231)
Somnolence (227)
Confusional State (208)
Malaise (205)
Agitation (189)
Hyperhidrosis (180)
Accidental Overdose (180)
Chest Pain (174)
Product Formulation Issue (174)
Insomnia (170)
Loss Of Consciousness (167)
Amnesia (165)
Fall (159)
Dyspnoea (157)
Suicidal Ideation (152)
Anorexia (140)
Chills (140)
Dizziness (138)
Aggression (136)
Feeling Abnormal (125)
Euphoric Mood (124)
Decreased Appetite (123)
Condition Aggravated (123)
Fatigue (121)
Anger (121)
Completed Suicide (120)
Abdominal Discomfort (113)
Road Traffic Accident (113)
Blood Pressure Increased (112)
Lethargy (109)
Pruritus (102)
Myocardial Infarction (97)

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Recent Reviews

have been taking dulotine 90mg and oxycontin 40mg pregablin 75mg would this damage my kidneys


Had left half of an 40mg Oxycontin pill on my night stand! Came back about an hour later and was unable to locate pill! Time was approximately 5:00 PM! 4 to 4 1/2 hours later, younger stepsister, age 8, strangely says she took pill by accident! What

Have gotten Phrenic nerve paralysis since taking Chantix...

Hi, I'm not exsperiencing this first hand, but I am second hand. My bestfriend is. Let me tell you, I feel like I am. She has 7 days under he belt offically. I am so proud of her, considering how she was day 5 and 7, I don't think many people would s

How does it affect ur families

I have lost (broken off) seven lower teeth in last 60 days. Dentist say because OXYICONTIN causes severe dry mouth which creates optimal conditions for getting cavities and super fast (No cavities needing feeling at cleaning and NINE six months later

Like to talk to anyone who had nerve damage (pne) after senergy ez was put in thanks liz

Severe back pain that goes throught to my stomach. i also feel very lehargic and i have wet myself a few times

<b>Exacerbating Lumbo-Sacral pain leading to current dissability. Hundreds of 'granules' of oil remained inside the spinal canal and cauda equina causing excruciating nerve pain leading to arachnoidtis :</b>

46-yr old healthy female approx 110 lbs. injected with Carbocaine during routine dental visit. Jolt of pain felt when needle hit the lingual nerve and the following have resulted: continual burning dysthestetic pain on one side of tongue, debilitatin

A filling from 1 of my front teeth came out a couple days ago. the next day the pain got worse because the nerve was i applied orajel max strength to the tooth the pain went away quick i applied it to the tooth and the gum around it.nex

A friend of mine has cancer and the doctors are talking about having surgery and removing the sciatica nerve. My question is will he be a function with this removal.

After a few months on serostim I have noticed much pain in my hands and fingers. It almost feels as though I have a pinched nerve in my neck and it is effecting my arms, hands and fingers. Is this one of the side effects?

Can I use Tizanidine for sciatic nerve in my left leg it hurts

Due to my nervous system disorer, doctor gave me two nerve medicines. I couldn't take the first one which caused me total weakness and disorientation. I take the 2nd one, Sertaline, half a tablet daily. I have one kidney only, so I take everything in

During posterior fossa craniectomy, while my head was stablilized in cranial tongs, the lower half of the Skytron OR table collasped to the floor.As my legs were strapped to the fallen end of the table I sustained nerve injury 'overstretch'

For the last two weeks I have been taking a lowish dose of Gabapentin for night-time nerve pain (100gm three times a day and then 200mg at night.) It has worked brilliantly for the pain and I was ecstatic BUT I have now wet the bed two nights in a r

Have been on Eutirox for the past 6 months, during my pregnancy everything seemed fine but nowI am havinglots of joint pains, heavy tongue feeling, nerve problems e.g. holding my pen to write. I am also worried because a friend di

Nerve Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Registry of Avance Nerve Graft Evaluating Utilization and Outcomes for the Reconstruction of Peripheral Nerve Discontinuities
Condition: Peripheral Nerve Injuries
Interventions: Other: Processed Human Nerve Tissue Scaffold;   Other: Standard Treatment, Autogenous Nerve Graft, Direct Suture, etc.
Outcome Measures: Incidence of Avance Nerve Graft Related Adverse Events;   Improvement in Function in Injured Peripheral Nerve;   Rate of Return of Meaningful Recovery Following Peripheral Nerve injury
2 Not yet recruiting Comparison of Two Techniques of Sciatic Nerve Block With Levobupivacaine 0.5% in Orthopedic Surgery
Condition: Anesthesia
Interventions: Procedure: Sciatic Nerve anesthesia blockade at bifurcation.;   Procedure: Sciatic Nerve blockade 2 cm beyond the bifurcation;   Drug: Levobupivacaine 0.5%: 20 ml;   Device: Portable Ultrasound Machine: Sonosite, M-Turbo, Bothell, WA;   Device: Insulated Needle, (Stimuplex; Braun, Melsungen, Germany);   Drug: supplemental oxygen;   Drug: Midazolam;   Drug: Intravenous analgesics;   Procedure: Saphenous Nerve block
Outcome Measures: Latency period of sciatic Nerve block.;   Success of sciatic Nerve block;   Patient satisfaction;   Sensory block;   Motor block;   First analgesic;   Visual analog scale at rest;   Dynamic visual analog scale;   Intraneural injection;   Vascular puncture;   Paresthesia during the procedure;   Systemic toxicity of local anesthetics;   Hematoma;   Muscle weakness;   Altered sensitivity;   Cramps postoperative;   Punctures;   Time for the execution of Nerve block
3 Not yet recruiting Comparison of Processed Nerve Allograft and Collagen Nerve Cuffs for Peripheral Nerve Repair
Condition: Peripheral Nerve Discontinuities
Interventions: Biological: Processed Nerve Allograft (human);   Device: Collagen Nerve Cuff
Outcome Measure: Recovery of Static Two Point Discrimination Assessed by Discriminator (in mm)
4 Not yet recruiting Evaluation of Use of Ultrasound for Greater Palatine Nerve Block and Inferior Alveolar Nerve Blocks: An Open Label Feasibility Study
Conditions: Greater Palatine Nerve Block;   Inferior Alveolar Nerve Block
Intervention: Procedure: US guided block
Outcome Measure: Success rate of Nerve blocks
5 Unknown  Anatomy Study in Control Nerve From Normal Human
Conditions: Anatomy of Normal Human Nerves;   Microscopic Study;   Myelinated Nerve and Unmyelinated Nerve Study
Intervention: Procedure: harvest Nerve
Outcome Measure:
6 Unknown  Preventing the Obturator Nerve Reflex
Condition: Bladder Injury
Intervention: Procedure: Obturator Nerve block
Outcome Measure: Nerve conduction velocity
7 Recruiting Autologous Peripheral Nerve Grafts Into the Substantia Nigra of Subjects With PD Undergoing Deep Brain Stimulation
Condition: Parkinson's Disease
Intervention: Procedure: Implantation of the Peripheral Nerve Graft
Outcome Measures: Safety and Tolerability of Nerve Graft Implantation;   Peripheral Nerve Graft Efficacy -- clinical improvement;   Peripheral Nerve Graft Efficacy -- Therapy Reduction;   Peripheral Nerve Graft Efficacy -- Quality of Life
8 Recruiting Ultrasound Guided Obturator Nerve Block for Total Knee Replacement (TKR)
Conditions: Total Knee Replacement;   Surgery
Interventions: Other: Sciatic, femoral, obturator Nerve blocks;   Other: Sciatic Nerve block, posterior lumbar plexus block
Outcome Measures: Feasibility of TKR surgery under ultrasound guided sciatic Nerve block plus femoral Nerve block plus obturator Nerve block measured with Pain Score on the Visual Analog Scale;   Intraoperative opioid consumption for TKR surgery under ultrasound guided sciatic Nerve block plus femoral Nerve block plus obturator Nerve block
9 Recruiting Ultrasound Plus Nerve Stimulator Versus Nerve Stimulator Guided Lumbar Plexus Block
Condition: Knee Arthroscopy Surgery
Interventions: Procedure: Ultrasound and Nerve stimulator guided lumbar plexus block;   Procedure: Nerve stimulator guided lumbar plexus block;   Procedure: Nerve stimulator guided sciatic Nerve block
Outcome Measures: Time required to a complete lumbar plexus block;   Total ultrasound visibility score (UVS);   Hemodynamic changes after skin incision;   Performance time of block;   Number of needle passes during block;   Minimal stimulating current of the needle;   Onset time of sensory block to cold and pinprick;   Onset time of motor block;   Incidence of paresthesia during and after block;   Incidence of accidental vascular puncture;   Postoperative pain score;   Patient acceptance
10 Not yet recruiting Electrical Nerve Stimulation for Overactive Bladder a Comparison of Treatments
Conditions: Overactive Bladder;   Urge Urinary Incontinence
Interventions: Device: PTNS (Percutaneous Tibial Nerve Stimulation;   Device: TENS (Transcutaneous Electrical Nerve Stimulation)
Outcome Measure: Percutaneous Tibial Nerve Stimulation vs. Transcutaneous Electrical Nerve Stimulation for Overactive Bladder: A Randomized Trial
11 Not yet recruiting Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair
Condition: Injury of Anterior Cruciate Ligament
Interventions: Drug: bupivacaine;   Device: continuous perineural infusion catheter
Outcome Measures: opioid pain medication;   duration of analgesia in the single injection Nerve block and the continuous peripheral neural infusion group
12 Unknown  Can the Femoral Nerve Block be Improved by Ultrasound Guidance?
Condition: Pain
Interventions: Procedure: determination of method with highest efficacy (ultrasound or Nerve stimulator);   Procedure: Nerve stimulator;   Procedure: loss of resistance
Outcome Measures: percentage of patients with effective regional analgesia;   hospital mortality;   sensory function in lateral cutaneous Nerve;   sensory function of femoral Nerve;   sensory function of obturator Nerve;   motor function of obturator Nerve;   motor function of femoral Nerve;   acute mental test scores;   total morphine dose administered;   day first mobilise post operatively;   patient satisfaction scores
13 Recruiting Nerve Decompression for Ulcer Recurrence Avoidance (DURA)
Conditions: Diabetic Ulcer of Plantar Aspect of Left Foot;   Diabetic Ulcer of Plantar Aspect of Right Foot;   Diabetic Polyneuropathy
Intervention: Procedure: Nerve decompression
Outcome Measures: occurrence of plantar foot ulceration wound;   occurrence of delayed wound healing;   Visual Analog Pain Score
14 Recruiting Continuous Popliteal Nerve Blocks: Effect of Perineural Catheter Tip Location Relative to the Sciatic Nerve Bifurcation on Postoperative Analgesia
Conditions: Popliteal Nerve Block;   Foot Surgery;   Ankle Surgery;   Popliteal Bifurcation
Interventions: Procedure: Catheter Placed At Bifurcation;   Procedure: Catheter Placed 5cm Above Bifurcation
Outcome Measures: Average Pain;   Analgesic Use;   Sleep Disturbances;   Infusion Side Effects;   Satisfaction of pain control
15 Unknown  Can Ultrasound Predict Nerve Injury Following Posterior Tibial Nerve Block in Patients With Peripheral Neuropathy?
Condition: Diabetic Neuropathy
Intervention: Procedure: Nerve conduction study and Ultrasound of the PTN
Outcome Measures: Interval worsening of the severity of neuropathy;   New functional neuropathy defined as any new sensory or motor deficit compared to preoperatively.
16 Recruiting Simple Decompression Versus Anterior Transposition of the Ulnar Nerve
Conditions: Humeral Fractures;   Ulnar Nerve Compression
Interventions: Procedure: Simple decompression;   Procedure: anterior subcutaneous transposition
Outcome Measures: The primary outcome will be signs of ulnar neuropathy, measured using two clinical staging systems to assess the degree of dysfunction of the ulnar Nerve (the classification system of Gabel and Amadio13).;   Secondary outcome measurement will include a patient-oriented, limb-specific, functional measurement questionnaire (Disabilities of the Arm, Shoulder and Hand Instrument-DASH)
17 Not yet recruiting Prospective Post-market Evaluation of an Echogenic Catheter
Condition: Peripheral Nerve Block Procedure
Interventions: Device: EchoGlo Nerve Block Catheter;   Device: Pajunk® Nerve Block Catheter
Outcome Measures: Visibility of entire catheter length;   Visibility of catheter tip;   Quality of the block;   Block failure rate
18 Recruiting The Efficacy and Safety of Nerve-sparing Radical Hysterectomy in Cervical Cancer
Condition: Cervical Cancer
Intervention: Procedure: Nerve sparing radical hysterectomy
Outcome Measures: Incidence of bladder dysfunction after surgery;   rectal & anal function after surgery;   Sexual function;   Quality of life;   operative time;   amount of bleeding in operation;   frequency of blood transfusion;   amount of blood transfusion;   postoperative complication;   time from surgery to return to work;   management cost;   size of resected parametrial tissue;   2year disease free survival
19 Unknown  Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients With Symptomatic Diabetic Neuropathy With Chronic Nerve Compression
Condition: Painful Diabetic Neuropathy
Intervention: Procedure: Nerve Decompression
Outcome Measures: To determine if Nerve decompression of lower extremities in patients suffering from painful symptomatic diabetic neuropathy with chronic Nerve compression, has a significant impact on alleviation of pain, and improvement in quality of life.;   To measure changes in quality of life. This includes medication changes, pain relief, restoration of sensation, etc.
20 Recruiting Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
Conditions: Total Knee Arthroplasty;   Total Knee Replacement;   Femoral Nerve Block;   Adductor Canal Block
Interventions: Procedure: Femoral Nerve Block. Adductor Canal Block;   Drug: Ropivacaine
Outcome Measures: Morphine consumption;   Pain scores;   Side effects of opioids- sedation, nausea and vomiting;   Quadriceps strength, ability to mobilise