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Neuralgia and Gabapentin

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Neuralgia Symptoms and Causes

What is shingles?

Shingles is an outbreak of rash or blisters on the skin. It is caused by the varicella-zoster virus - the same virus that causes chickenpox. After you have chickenpox, the virus stays in your body. It may not cause problems for many years. But as you get older, the virus may reappear as shingles.

Is shingles contagious?

Shingles is not contagious. But you can catch chickenpox from someone with shingles. If you've never had chickenpox or the chickenpox vaccine, try to stay away from anyone who has shingles.

If you have shingles, try to stay away from anyone who has not had chickenpox or the chickenpox vaccine, or anyone who might have a weak immune system.

Who is at risk for shingles?

Anyone who has had chickenpox is at risk for getting shingles. But this risk goes up as you get older; shingles is most common in people over age 50.

People with weakened immune systems are at higher risk of getting shingles. This includes those who

  • Have immune system diseases such as HIV/AIDS
  • Have certain cancers
  • Take immunosuppressive drugs after an organ transplant

Your immune system may be weaker when you have an infection or are stressed. This can raise your risk of shingles.

It is rare, but possible, to get shingles more than once.

What are the symptoms of shingles?

Early signs of shingles include burning or shooting pain and tingling or itching. It is usually on one side of the body or face. The pain can be mild to severe.

One to 14 days later, you will get a rash. It consists of blisters that typically scab over in 7 to 10 days. The rash is usually a single stripe around either the left or the right side of the body. In other cases, the rash occurs on one side of the face. In rare cases (usually among people with weakened immune systems), the rash may be more widespread and look similar to a chickenpox rash.

Some people may also have other symptoms:

  • Fever
  • Headache
  • Chills
  • Upset stomach
What are the complications of shingles?

Shingles can cause complications:

  • Postherpetic Neuralgia (PHN) is most common complication of shingles. It causes severe pain in the areas where you had the shingles rash. It usually gets better in a few weeks or months. But some people can have pain from PHN for many years, and it can interfere with daily life.
  • Vision loss can happen if shingles affects your eye. It may be temporary or permanent.
  • Hearing or balance problems are possible if you have shingles within or near your ear. You may also have weakness of the muscles on that side of your face. These problems can be temporary or permanent.

Very rarely, shingles can also lead to pneumonia, brain inflammation (encephalitis), or death.

How is shingles diagnosed?

Usually your health care provider can diagnose shingles by taking your medical history and looking at your rash. In some cases, your provider may scrap off tissue from the rash or swab some fluid from the blisters and send the sample to a lab for testing.

What are the treatments for shingles?

There is no cure for shingles. Antiviral medicines may help to make the attack shorter and less severe. They may also help prevent PHN. The medicines are most effective if you can take them within 3 days after the rash appears. So if you think you might have shingles, contact your health care provider as soon as possible.

Pain relievers may also help with the pain. A cool washcloth, calamine lotion, and oatmeal baths may help relieve some of the itching.

Can shingles be prevented?

There are vaccines to prevent shingles or lessen its effects. The Centers for Disease Control and Prevention recommends that healthy adults 50 years and older get the Shingrix vaccine. You need two doses of the vaccine, given 2 to 6 months apart. Another vaccine, Zostavax, may be used in certain cases.

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Gabapentin Side Effects

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Myoclonus (108)
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Amnesia (104)
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Oedema Peripheral (83)
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Rash (80)
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Hallucination (72)
Muscular Weakness (71)
Sedation (71)
Myalgia (70)
Loss Of Consciousness (70)
Renal Failure Acute (69)
Hypoaesthesia (66)
Muscle Spasms (66)

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Recent Reviews

Be careful! Avoid Gabapentin at all costs! My mother's doctor ordered a 900 mg/day dose. In the 2 years she was under this dose, she fell 5 times! No doctor 'suspected' this drug! Then, he increased the dose to...1800 mg/day! I almost lost her! I am

Dose Gabapantin have any ting to do with the nearves in your body

For the last two weeks I have been taking a lowish dose of Gabapentin for night-time nerve pain (100gm three times a day and then 200mg at night.) It has worked brilliantly for the pain and I was ecstatic BUT I have now wet the bed two nights in a r

GABAPENTIN noticed that medication got worsen n Nurgloist n don't listin. My problem n even rash n stomach ach n was getting stress out n decided go different doctor n was. Going take that chance with my n stop going to Nurgloist n been two.n bo

Great so far for my anxiety... just side effects has ... sexually saticfied,nausea little bit.. dizzynezz! lolz.. but great medication/ i think..

Having racing thoughts and unmotivated *DONT_KNOW*

Hear voices

Hello, I've been taking a cocktail of meds for 9 years to help treat acute nerve pain from a severe Brachial Plexus nerve avulsion C 7, 8, T1 and Spinal cord injury. Medications: Gabapentin 3600 mg., Methadone 100 mg. , Baclofen 20 mg. every 8 hour

I am having trouble falling to sleep, and I feel like I' having anxiety attacks I stopped the 400 Mg and I am taking 2 100 MGS now. I am doing this on my own , until I see my Dr next week. .

I am just starting Gabapentin to help with phantom pain from a BKA (below-knee-amputation). I am taking 600 mg and am scheduled to increase to 900 mg, then review results with my doctors. One of the side effects I seem to have is

<b>Describe Your Bisoprolol Experience Here:&lt;/b Trigeminal neuralgia. , left neurological chest pain Dose 1.25 twice daily</b>

Gleevec aggravating trigeminal neuralgia

Hi I take Oxcarbazepine for trigeminal neuralgia and i am having difficulty concentrating and seeing clearly, does anyone else have the same or similar experience

Hi Joe - if you already have heart failure, DO NOT take Lyrica. Warnings are on the leaflet within the tablet package. My husband increased his dosage (ignoring my warnings) to 750mg/day for severe trigeminal neuralgia, way above the recommended maxi

I am a homeopath.I am treating a patient, who is suffering from trigeminal neuralgia since 2 yrs.Previously he was a victim of repeated attacks of colds &amp; cough, &amp; he was using Actifed oral, half tablet twice/week,for 20 yrs.RCC stopp

I have an AVM. I was born with this, and it was first found in an MRI 13 years ago. While testing for my symptoms of facial pain (Neuralgia They didnt know it at the time) 2-1/2 years ago, I had another MRI. These results were compared to t

I was prescribed Lyrica by my doctor right after my 18th birthday. I was diagnosed with Post Herpetic Neuralgia (after pain from Shingles) when I was seventeen. Lyrica was the most horrible thing I've ever taken. While taking Lyrica, I was taking 18

James, I realised yours is an old posting, but 3 x 300mg a day is WAY over the maximum recommended dosage! My husband has trigeminal neuralgia and was so desperate to relieve the pain he put himself on 750mg a day (maximum is 600mg). As a direct resu

My husband died in Dec 2007 due to a contradiction of taking Lyrica with Effexor XR. He was taking Lyrica for post herpetic neuralgia. His doc decided in Noc '07 to have him take it daily (ie prophlactically), 2 weeks before his death the doc ha

Trigeminal neuralgia and Chantix. hs anyone been diagonoised with since stopping Chantix.

Neuralgia Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome
Condition: Restless Leg Syndrome
Interventions: Drug: Gabapentin immediate release (Neurontin);   Drug: Gabapentin enacarbil extended release (Horizant)
Outcome Measures: International Restless Leg Syndrome Rating Scale (IRLS);   Restless Leg Syndrome Quality of Life Scale (RLSQoL)
2 Not yet recruiting Pain Control in Pediatric Posterior Spine Fusion Patients: The Effect of Gabapentin
Condition: Pain, Postoperative
Interventions: Drug: Gabapentin;   Drug: Simple Syrup
Outcome Measures: Difference in pain control when adding Gabapentin to a multimodal pain management protocol in pediatric post-operative posterior spinal fusion patients.;   Determine if opiate usage is less in the Gabapentin group versus control.
3 Recruiting Effectiveness of Gabapentin on Chronic Irritability in Neurologically Impaired Children
Conditions: Neurologically Impaired;   Irritable Mood;   Signs and Symptoms, Digestive;   Sleeplessness;   Chronic Pain
Interventions: Drug: Gabapentin;   Drug: placebo
Outcome Measures: Symptom relief for chronic irritability in neurologically impaired children using Gabapentin.;   Prevalence of associated gastrointestinal and sleep problems in neurologically impaired children and improvement using Gabapentin.
4 Recruiting The Effect of Gabapentin on Thoracic Epidural Analgesia Following Thoracotomy
Condition: Pain, Postoperative
Interventions: Drug: Gabapentin;   Drug: Placebo
Outcome Measures: Persistent post surgical pain;   Acute postoperative pain;   Usage of epidural infusion of local and opioid analgesics (ml);   Early postoperative pain;   Consumption of opioid analgesics;   Time to first request for additional analgesics;   Analgesia related side-effects;   Convalescence of gastrointestinal function;   Health related quality of life;   Patient satisfaction;   Intensity of preoperative anxiety;   Convalescence of lung function (spirometry);   Sleep quality;   Walking distance (meters);   Fatigue;   Hospital length of stay (days);   Use of a vasopressor agent to correct hypotension
5 Recruiting Postoperative Tramadol/Gabapentin/Acetaminophen Versus Tramadol/Placebo/Acetaminophen
Condition: Pain
Interventions: Drug: Gabapentin;   Drug: Tramadol;   Drug: Ibuprofen
Outcome Measures: Efficacy of scheduled tramadol + PRN ibuprofen vs. scheduled tramadol + scheduled Gabapentin + PRN ibuprofen;   Side effects of scheduled tramadol + PRN ibuprofen vs. scheduled tramadol + scheduled Gabapentin + PRN ibuprofen
6 Recruiting Does a Perioperative Course of Gabapentin Improve Analgesia After Cesarean Delivery?
Condition: Pain
Interventions: Drug: Gabapentin;   Drug: lactose
Outcome Measures: VAS score (VAS 0-100 mm) for maternal pain on movement at 24 hours after surgical incision.;   VAS score on movement at 48 hours after surgical incision;   VAS scores at rest at 24 and 48 hours after surgical incision;   Maternal satisfaction scores at 24 and 48 hours after surgical incision.;   Opioid use in the first 48 hours after surgical incision;   Time to first analgesic;   Sedation;   Neonatal apgar scores;   Breastfeeding issues;   NICU admission
7 Recruiting Quality of Life Study Using Gabapentin Versus Venlafaxine in Treating Hot Flashes in Patients With Prostate Cancer
Condition: Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Interventions: Drug: Gabapentin;   Drug: Venlafaxine
Outcome Measures: Changes in quality of life;   compare toxicity rates between the Gabapentin and venlafaxine treatment groups;   Assess changes in the hot flash scores for the two arms;   Assess changes in quality of life using the Hot flash related Daily Interference Scale (HFRDIS)
8 Recruiting Gabapentin for Insomnia Symptoms and Nighttime Vasomotor Symptoms in Peri- and Postmenopausal Women
Conditions: Menopause;   Hot Flashes;   Vasomotor Disturbance
Intervention: Drug: Gabapentin
Outcome Measures: Tolerability of Gabapentin;   VMS frequency, severity, and bothersomeness;   Subjective sleep quality;   Anxiety;   Depressed mood
9 Recruiting A Trial of Gabapentin in Vulvodynia: Biological Correlates of Response
Condition: Vulvodynia
Intervention: Drug: Gabapentin extended-release
Outcome Measures: The primary outcome measure of this project are to test the prediction that pain from tampon insertion is lower in PVD patients when treated with Gabapentin compared to when treated with placebo.;   The secondary outcome measure is to perform a mechanism-based analysis of Gabapentin effectiveness, and to gain insight into the underlying pathophysiology of subtypes of PVD that may lead to more specific treatment options.
10 Recruiting Clinical Trial of Gabapentin to Improve Postoperative Pain in Surgical Patients
Condition: Postoperative Pain
Intervention: Drug: Gabapentin
Outcome Measures: Postoperative delirium and cognitive decline;   Postoperative opioid doses and pain scores
11 Unknown  Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy
Condition: Postoperative Pain
Interventions: Drug: Gabapentin;   Drug: pregabalin
Outcome Measure: Decreased overall pain score as measured by the visual analogue scale
12 Recruiting Safety and Efficacy of Gabapentin for Neuropathic Pain in Fabry Disease
Conditions: Fabry Disease;   Neuropathic Pain
Interventions: Drug: Gabapentin;   Drug: placebo
Outcome Measures: average reduction in hydrocodone-acetaminophen use;   Number and type of adverse events;   Pain levels;   Define therapeutic level for Gabapentin
13 Unknown  Gabapentin in Functional Dyspepsia Refractory to Proton Pump Inhibition
Condition: Functional Dyspepsia
Interventions: Drug: Gabapentin;   Drug: Placebo
Outcome Measures: The primary outcome will be the adequacy of symptom control during the last week of the study.;   Secondary outcomes equate dyspepsia symptoms with quality of life. The Nepean Dyspepsia Index scores patients on five categories while the Global Overall Symptom Scale measures the severity of dyspepsia on a 1-7 scale.
14 Recruiting Efficacy and Safety of Gabapentin in Treating Overactive Bladder
Conditions: Urinary Frequency;   Urinary Urgency;   Nocturia;   Incontinence;   Detrusor Uninhibited Activity;   Quality of Life
Interventions: Drug: Gabapentin;   Drug: Solifenacin Succinate;   Drug: Placebo drugs
Outcome Measures: improvement of symptom domain means decreased frequency to less than 8 micturitions per 24 hours, no urgency noted per 24 hrs and less that 3 wakening at bedtime for micturation.;   Improvement of bladder function domain means increased bladder capacity and decreased overactive detrusor as recorded in urodynamic study.;   Improvement in quality of life domain means increased overall quality of life as perceived and result in OAB-q
15 Not yet recruiting Effect of Gabapentin on Pain of the Second Cataract Surgery
Condition: Hyperalgesia
Interventions: Drug: Gabapentin;   Drug: placebo
Outcome Measures: proportion of subjects who answer that "pain was greater" in the second eye surgery;   perioperative pain
16 Recruiting Preoperative Gabapentin for Post-tonsillectomy Pain in Children
Condition: Post Operative Pain Management in Children With Tonsillectomy/Adenoidectomy
Interventions: Drug: Gabapentin;   Drug: liquid placebo
Outcome Measures: Total oral analgesia consumption;   Self-report pain score
17 Recruiting Gabapentin Treatment of Cannabis Dependence
Conditions: Cannabis Dependence;   Cannabis Withdrawal;   Cognitive Deficits
Interventions: Drug: Gabapentin 1200mg/day;   Drug: Placebo
Outcome Measure: Cannabis Use
18 Recruiting Steroids Versus Gabapentin
Conditions: Sciatica;   Radiculopathy
Interventions: Procedure: epidural steroid injection;   Procedure: Sham epidural steroid injection;   Drug: Gabapentin;   Drug: Placebo Gabapentin
Outcome Measures: leg pain;   Back pain;   Oswestry disability index;   satisfaction
19 Recruiting GRASSP: Gralise® for Spine Surgery Pain
Condition: Post-laminectomy Pain Syndrome
Interventions: Drug: Gralise®;   Drug: Placebo
Outcome Measures: Numeric Rating Scale (NRS);   Visual Analog Scale (VAS);   Patient Global Assessment (PGA);   McGill Pain Questionnaire-2 (MPQ-2);   Modified Brief Pain Inventory- short form (mBPI-sf);   Insomnia Severity Index (ISI)
20 Recruiting Maintenance Gabapentin to Prolong Pregnancy.
Condition: Preterm Labor, Premature Birth
Intervention: Drug: Gabapentin
Outcome Measure: Rate of premature birth (before 37 weeks gestation)