Osteoarthritis and Bystolic


Osteoarthritis Symptoms and Causes

Osteoarthritis is the most common form of arthritis. It causes pain, swelling, and reduced motion in your joints. It can occur in any joint, but usually it affects your hands, knees, hips or spine.

Osteoarthritis breaks down the cartilage in your joints. Cartilage is the slippery tissue that covers the ends of bones in a joint. Healthy cartilage absorbs the shock of movement. When you lose cartilage, your bones rub together. Over time, this rubbing can permanently damage the joint.

Risk factors for Osteoarthritis include

  • Being overweight
  • Getting older
  • Injuring a joint

No single test can diagnose Osteoarthritis. Most doctors use several methods, including medical history, a physical exam, x-rays, or lab tests.

Treatments include exercise, medicines, and sometimes surgery.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for osteoarthritis

osteoarthritis treatment research studies

Bystolic clinical trials, surveys and public health registries

Find Drug Side Effect reports

Bystolic Side Effects

Fatigue (99)
Dizziness (84)
Headache (75)
Dyspnoea (63)
Blood Pressure Increased (53)
Heart Rate Decreased (47)
Oedema Peripheral (46)
Insomnia (46)
Nausea (42)
Asthenia (39)
Chest Pain (36)
Bradycardia (34)
Diarrhoea (34)
Rash (31)
Pruritus (29)
Alopecia (29)
Pain In Extremity (27)
Paraesthesia (25)
Chest Discomfort (21)
Arthralgia (20)
Palpitations (19)
Hypotension (19)
Abdominal Pain Upper (19)
Depression (18)
Fall (18)
Weight Increased (18)
Vision Blurred (17)
Abdominal Distension (17)
Hypertension (16)
Cough (16)
Abnormal Dreams (15)
Abdominal Discomfort (15)
Heart Rate Increased (15)
Pain (15)
Hypoaesthesia (15)
Muscle Spasms (15)
Blood Glucose Increased (14)
Joint Swelling (14)
Myalgia (14)
Migraine (13)
Erythema (13)
Anxiety (13)
Convulsion (12)
Hyperhidrosis (12)
Unevaluable Event (12)
Tremor (12)
Weight Decreased (12)
Heart Rate Irregular (11)
Vomiting (11)
Malaise (11)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)

Recent Reviews

Started taking Bystolic 5mg on Thursday for tachycardia. Sunday, had blurred vision. (Was driving and it was so bad that the interstate signs were blurred!) Stopped medicine and called doctor on Monday. Tuesday, called back because nobody saw f

Ok,So My Doctor just gave Bystlic to me I was on a different one and now this Im so so afriad to take this im only 33 yrs old and the blood pressure meds Im on it not lowering it enought..... I guess I will not take this med..</span>

<strong>I have been taking Bystolic for about a month, my right leg has been 'killing' me ever since, I have alot of knee pain, and constant cramps in my right calf. The pain just seems to travel up and down my leg,can this be caused by Bystoli

<strong>I took Bystolic 5 mg for 3 days. Immediately started feeling bad.Heartrate is still 117 to 125, and blood pressure went up.It is 168/125.He gave me Bumex 1 mg with this. I take the KLOR 40 potasium with it. I am quiting both. Can not sl

64 years old. Good health, high BP extreme tension stress from work. Started lisinopril didn't lower BP, changed to Bystolic 10mg, lowered BP quickly, Constantly tired feeling, vey dizzy mostly in the morning constant coughing up mucus, lungs clear

8-) 8-) 8-)

About a month ago I had a dr. appt and my blood pressure was a little elevated although I am taking 300mg of cartia xt and hctz 37.5/triam25mg.My M.D.,thought that I should also take 10mg of bystolic, about 3 to 4 weeks into takin

After two week my chest got tight. Couldn't breath right. And my back by my shoulder blade hurt. I was on 5 mg. I'm going to try some natural ways celery magnesium garlic.

Bystolic caused weight gain and gout

Bystolic has dropped my bp but my pulse still remains pretty fast.

How long should one remain off work with lower leg (both legs) cellulitis? It is my 4th bout of this in past few years. I also have osteoarthritis in my knees.

I am on 20mg side effect sever sweatingi suffer from osteoarthritis in lower back

I am unable to walk following my Lupron treatment. I experienced extreme muscle weakness and loss of function in my right quad muscles. I also had prominent loss of fatty bopne marrow, joint degenerative disease, osteoarthritis, vitamin D deficienc

I got infusion of Reclast in December 2008 and experienced no side affects until a few weeks ago. Now I know I have some osteoarthritis &amp;amp; scoliosis, but have never experienced pain so severe &amp;amp; disabling. I haven't altered my r

I had my infusion in March 2008 and I'm still suffering with shoulder, wrist, fingers, hip and ankle pain. My fingers and wrists are swollen and it is very hard to use my fingers. Reclast has ruined my quality of life. Now I have osteoarthritis th

I have been taking Fenac for Osteoarthritis for a few weeks this time. Every time I take 50-100 I begin to get feel bloated, then I begin to have pain in my feet and hands and they feel tight as though I am retaining fluid in them. In the mornings wa

I have deveolped cellulitis toe nail and funger nails and believe it is because of taking Mobic I have osteoarthritis knee (macerated meniscus)

I have osteoarthritis in both knees and one hip. I do supervised weight-training 3 times a week to strengthen muscles around these joints and for general fitness. This helps immensely but I still experience a lot of pain and stifness most days, espec

I just have had a tooth extraction and implant for a left molar. The dentist asked me if I was taking anything for osteoarthritis. I said Boniva. He stated that boniva and Fosomax was detrimental to wound healing and that it opened the osteoblast

I was taking Mobic for Osteoarthritis in both knees, I am a nurse and by the end of the day I have a great deal of pain from walking all day. My doctor prescribed Celebrex in the hopes it would help, after 1 week on Celebrex I did not have any addit

Osteoarthritis Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Comparative Effects of Nebivolol and Metoprolol on Femal Sexual Function
Conditions: Hypertension;   Female Sexual Dysfunction
Interventions: Drug: nebivolol and metoprolol succinate;   Drug: metoprolol succinate and nebivolol
Outcome Measures: Change in FSF and CSFQ, two validated questionnaires for assessment of sexual function.;   The effects of nebivolol and metoprolol on sexual function and to compare the effects of both drugs on vitality, work and life performance, and work and life satisfaction.
2 Unknown  Comparative Effects of Nebivolol Versus Placebo on Sodium Sensitivity of Blood Pressure in Hispanic Postmenopausal Women With Hypertension
Condition: Hypertension
Interventions: Drug: nebivolol;   Drug: Nebivolol
Outcome Measures: Change and percentage change in systolic, diastolic and mean blood pressure by ABPM from final day of low sodium to the final day of high sodium in nebivolol versus placebo;   Differences in renal sodium excretion in response to an acute sodium load during treatment with either nebivolol or placebo.
3 Recruiting Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
Condition: Hypertension
Interventions: Drug: Metoprolol succinate;   Drug: Nebivolol;   Drug: Hydrochlorothiazide;   Drug: DEFINITY®;   Procedure: Non-invasive measurement of Cardiac Output (CO);   Procedure: Flow mediated vasodilation;   Procedure: Endothelial cell collection;   Procedure: Microvascular perfusion assessment using Definity
Outcome Measures: Endothelial cell protein expression;   Microvascular blood flow;   Flow mediated dilation (FMD)
4 Unknown  Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients
Condition: Marfan Syndrome
Interventions: Drug: Losartan and nebivolol;   Drug: Losartan;   Drug: Nebivolol
Outcome Measures: BSA and age-adjusted aortic root diameter (sinuses of Valsalva);   The pharmacokinetics of the two drugs by age and dosages;   Comparative evaluation of the serum levels of total and active TGFb;   Quantitative assessment of the expression of the mutated gene (FBN1, both 5' and 3');   Pharmacogenetic bases of drug responsiveness (Losartan: CYP2C9 gene) (Nebivolol: CYP2D6 gene);   Aortic valve regurgitation severity;   Left ventricular end-diastolic diameter;   Left ventricular ejection fraction;   Spirometric lung volumes and flows;   QoL evaluation basing on SF-36 questionnaire;   Arterial stiffness (carotids)
5 Recruiting Nebivolol Effects on Endothelial Function and Erectile Function
Condition: Erectile Dysfunction
Interventions: Drug: Nebivolol;   Drug: Sugar Pill
Outcome Measures: Primary objective is to determine if treatment with nebivolol improves endothelial function and erectile function in men with pre-hypertension and stage 1 hypertension. This will be assessed by change in IIEF-5 at baseline, 2 and 3 months;   Change in Endopat score;   Change in SphygmoCor results;   Change in SQOLM score
6 Recruiting Study to Evaluate Effect of Nebivolol on Angina in Women With Microvascular Disease
Condition: Microvascular Angina
Intervention: Drug: Nebivolol
Outcome Measures: Seattle Angina Questionnaire Score;   peak VO2 measured by cardiopulmonary exercise testing;   resource utilization questionnaire;   SF36
7 Recruiting Comparative Study of the Effects of Telmisartan and Nebivolol
Condition: Hypertension
Interventions: Drug: TELMISARTAN;   Drug: NEBIVOLOL
Outcome Measures: Change from baseline in 24h blood pressure;   Change from baseline in arterial stiffness
8 Unknown  Regression of Myocardial Steatosis by Nebivolol
Condition: Cardiac Steatosis and Lipotoxicity
Intervention: Drug: Nebivolol
Outcome Measures: Myocardial triglyceride content;   Cardiac function;   Regression of concentric cardiac remodeling;   Regression of steatosis in other non-adipocyte tissue;   Regression of subcutaneous fat
9 Unknown  Nebivolol and Endothelial Regulation of Fibrinolysis (NERF)
Conditions: Prehypertension;   Hypertension
Interventions: Drug: Nebivolol;   Drug: Metoprolol;   Drug: Placebo
Outcome Measure: Changes from baseline in endothelial t-PA release
10 Recruiting A Study Examining the Effects of Nebivolol Compared to Atenolol on Endothelial Function
Condition: Hypertension
Interventions: Drug: Nebivolol;   Drug: atenolol;   Drug: placebo
Outcome Measures: Comparing effects of nebivolol against atenolol and placebo on endothelial function;   Evaluate effects of nebivolol as compared to atenolol and placebo
11 Recruiting Nebivolol for the Prevention of Left Ventricular Systolic Dysfunction in Patients With Duchenne Muscular Dystrophy
Conditions: Duchenne Muscular Dystrophy;   Cardiomyopathy;   Heart Failure
Interventions: Drug: Nebivolol;   Drug: Placebo
Outcome Measures: Left ventricular systolic dysfunction;   Right ventricular ejection fraction;   NT-ProBNP;   Left ventricular dysfunction;   Hospitalizations;   Mortality
12 Not yet recruiting CPAP and Nebivolol in Hypertensive Obstructive Sleep Apnea (OSA) Patients.
Conditions: Hypertension;   Endothelial Dysfunction;   Obstructive Sleep Apnea
Interventions: Drug: Nebivolol;   Device: Continuous positive airway pressure (CPAP)
Outcome Measures: change in mean arterial blood pressure;   change in endothelial function
13 Unknown  Nebivolol and the Endothelin (ET)-1 System
Conditions: Prehypertension;   Hypertension
Interventions: Drug: Nebivolol;   Drug: Metoprolol;   Drug: Placebo
Outcome Measure: ET-1-mediated vasoconstrictor tone
14 Recruiting Comparison of 2 Beta Blocker Drugs on Peripheral Arterial Disease in Patients With High Blood Pressure
Conditions: Peripheral Artery Disease;   Hypertension
Interventions: Drug: nebivolol;   Drug: Metoprolol succinate
Outcome Measures: Peak Walking Time;   Walking Impairment Questionnaire;   Ankle-brachial index;   markers of inflammation.;   Claudication Onset Time
15 Recruiting Effect of Nebivolol on the Blood Flow in Hearts of Adults With High Blood Pressure and Abnormal Filling of Heart
Conditions: Hypertension;   Left Ventricular Diastolic Dysfunction
Intervention: Drug: Nebivolol
Outcome Measures: Improvement in exercise tolerance;   E velocity indexed to e' (E/e' ratio) of the left ventricle;   Untwist rate of the left ventricle
16 Recruiting Safety Study of Nebivolol for COPD Patients
Condition: High Blood Pressure
Interventions: Drug: Placebo;   Drug: Nebivolol
Outcome Measures: to assess blood pressure control;   to assess pulmonary function tests
17 Unknown  Influence of Nebivolol on Postmenopausal Women
Conditions: Hot Flashes;   Heart Rate;   Blood Pressure;   Endostatin;   Sexual Function
Outcome Measures: Number of hot flashes/palpitations;   Hemodynamic changes;   Sexual function;   Endostatin;   Quality of life
18 Recruiting Nebivolol Versus Sustained Release Metoprolol Succinate in Patients With Chronic Kidney Disease
Condition: Chronic Kidney Disease
Outcome Measures: Primary Efficacy;   Secondary Efficacy
19 Recruiting Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failure
Conditions: Pulmonary Hypertension;   Diastolic Heart Failure;   Heart Failure With Preserved Ejection Fraction
Intervention: Drug: Nebivolol
Outcome Measures: Changes in pulmonary vascular pressure;   Changes in 6-minute walk distance
20 Recruiting Treatment of Supine Hypertension in Autonomic Failure
Condition: Hypertension
Interventions: Drug: Clonidine;   Drug: Nitroglycerin transdermal;   Drug: Dipyridamole/ Aspirin (Aggrenox);   Drug: Desmopressin (DDAVP);   Drug: Sildenafil;   Drug: Nifedipine;   Drug: Hydralazine;   Drug: Hydrochlorothiazide;   Drug: Placebo;   Drug: Bosentan;   Drug: Diltiazem;   Drug: Eplerenone;   Drug: guanfacine;   Dietary Supplement: L-arginine;   Drug: captopril;   Drug: carbidopa;   Drug: losartan;   Drug: metoprolol tartrate;   Drug: nebivolol hydrochloride;   Drug: prazosin hydrochloride;   Drug: tamsulosin hydrochloride;   Other: Head-up tilt.;   Drug: aliskiren;   Other: Local heat stress
Outcome Measures: Decrease in supine systolic blood pressure;   Decrease in pressure natriuresis