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Polyarthritis and Ebetrexat

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Polyarthritis Symptoms and Causes

Juvenile arthritis (JA) is arthritis that happens in children. It causes joint swelling, pain, stiffness, and loss of motion. It can affect any joint, but is more common in the knees, hands, and feet. In some cases it can affect internal organs as well.

The most common type of JA that children get is juvenile idiopathic arthritis. There are several other forms of arthritis affecting children.

One early sign of JA may be limping in the morning. Symptoms can come and go. Some children have just one or two flare-ups. Others have symptoms that never go away. JA can cause growth problems and eye inflammation in some children.

No one knows exactly what causes JA. Most types are autoimmune disorders. This means that your immune system, which normally helps your body fight infection, attacks your body's own tissues.

JA can be hard to diagnose. Your health care provider may do a physical exam, lab tests, and x-rays. A team of providers usually treats JA. Medicines and physical therapy can help maintain movement and reduce swelling and pain. They may also help prevent and treat complications.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

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Ebetrexat Side Effects

Multi-organ Failure (15)
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Death (4)
Acute Coronary Syndrome (4)
Alopecia (3)
Dyspnoea (3)
Thrombocytopenia (3)
Device Dislocation (2)
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Cardiac Failure (1)
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Pneumonia (1)
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Radius Fracture (1)
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Mouth Ulceration (1)
Mucosal Inflammation (1)
Ulna Fracture (1)

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Recent Reviews

Polyarthritis Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.