Procedural and Oxycontin


Procedural Symptoms and Causes

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Procedural Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults
Conditions: Fracture;   Dislocation
Interventions: Drug: Procedural sedation with ketamine-propofol combination;   Drug: Procedural sedation with ketamine alone
Outcome Measures: Proportion of recovery agitation;   Time from first injection to optimal sedation;   Proportion of respiratory depression;   Proportion of arterial hypotension;   Proportion of vomiting;   Recovery time;   Proportion of Procedural failures;   Level of patient's satisfaction;   Level of care giver's satisfaction
2 Recruiting Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation
Condition: Procedural Sedation
Interventions: Drug: Propofol;   Drug: 1:1 Propofol/Ketamine;   Drug: 4:1 Propofol/Ketamine
Outcome Measures: Clinical interventions during sedation;   Hypoxia;   Respiratory depression;   Procedural pain and recall
3 Recruiting DAPPAR AF Dabigatran for Peri Procedural Anticoagulation During Radiofrequency Ablation of Atrial Fibrillation
Condition: Atrial Fibrillation
Intervention: Drug: dabigatran
Outcome Measure: The incidence of peri-Procedural major bleeding complications
4 Unknown  Analgesic Effect of Breastmilk for Procedural Pain in Preterm Infants
Condition: Procedural Pain
Interventions: Other: Breastmilk;   Other: Oral Sucrose
Outcome Measure: Decrement from 80 to 40% of frequency of DAN's scale score superior to 1 using breastmilk instead of oral sucrose
5 Unknown  The Effectiveness of Information and Relaxation on Pre-Procedural Block Anxiety and Procedural Discomfort During Medial Branch Block
Condition: Chronic Pain
Intervention: Behavioral: Relaxation and information session
Outcome Measures: Change in the anxiety level prior to the nerve block as per the state trait anxiety questionnaire;   Perceived pain as measured by NRS;   Unchanged catastrophization level;   Satisfaction level of the overall experience;   Ease of performing the nerve block
6 Recruiting Inhaled Nitrous Oxide for the Prevention of Emergence Reaction During Ketamine Administration in Adults, a Pilot Study
Conditions: Emergence Reaction;   Procedural Sedation
Intervention: Drug: Inhaled Nitrous Oxide
Outcome Measures: Emergence reaction;   Physiologic Measure;   Vitals;   Physician interventions;   Level of sedation;   Patient recall of procedure;   Total Ketamine dose;   Total time of nitrous use;   Physician procedure satisfaction score;   Patient procedure satisfaction score;   Nurse procedure satisfaction score;   Length of ED stay
7 Not yet recruiting Ketofol Versus Fentofol for Procedural Sedation in the Pediatric Emergency Department
Conditions: Emergency Department Procedural Sedation;   Fracture Reduction
Interventions: Drug: Ketofol;   Drug: Fentofol
Outcome Measures: Duration of Sedation;   Recovery Time;   Additional analgesia or sedation medications;   Efficacy of sedation for completion of procedure;   Satisfaction with sedation;   Incidence of adverse events
8 Recruiting Oral Sucrose Versus Glucose for Procedural Pain in Premature Neonates
Condition: Neonatal Procedural Pain
Interventions: Other: 24% oral sucrose;   Other: 30% oral glucose
Outcome Measure: We will determine the relationship between oral sucrose or glucose on urinary markers of ATP utilization, oxidative stress and cell injury compared to multiple doses of oral glucose (30%) or to control group
9 Recruiting Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation
Condition: Sedation
Interventions: Drug: Propofol;   Drug: Alfentanil;   Drug: Nitrous Oxide
Outcome Measures: Sub-clinical respiratory depression and clinical events associated with respiratory depression;   Time to return of baseline mental status;   Depth of sedation;   Patient reported pain;   Patient reported recall of the procedure
10 Recruiting Pre-Procedural Information Sheet Reduces Anxiety of Patients Before Urodynamic Studies
Condition: Anxiety
Interventions: Other: Information sheet;   Other: No information sheet
Outcome Measure: State Anxiety Inventory
11 Recruiting Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental Disability
Condition: Dental Care for Disabled
Interventions: Drug: Midazolam Mylan;   Drug: Lorazepam Mylan;   Drug: Valium + Akineton + Dehydrobenzperidol + Atropine sulfate
Outcome Measures: Level of cooperation of patient when receiving regular dental care;   Recording of vital parameters during regular dental care delivery;   Level of patient comfort and possible side-effects after dental treatment session
12 Unknown  Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation
Conditions: Pain;   Conscious Sedation
Intervention: Drug: ketamine
Outcome Measures: pain score;   necessity of cardiopulmonary intervention (Oxygen requirements)
13 Recruiting A Parental Educational Intervention to Facilitate Informed Consent for Pediatric Procedural Sedation in the Emergency Department
Condition: Informed Consent Process
Intervention: Other: computed-assisted information program
Outcome Measure: structured questionnaire
14 Recruiting Can Dexmedetomidine For Procedural Sedation In Knee Arthroplasty Reduce Postoperative Pain? A Randomized Control Study
Condition: Total Knee Arthroplasty
Interventions: Drug: Dexmedetomidine;   Drug: Normal Saline Placebo
Outcome Measures: morphine consumption;   time of first analgesia request
15 Unknown  Ulnar Nerve Block for Procedural Anesthesia - Wrist Versus Palm
Condition: Hand Surgery
Intervention: Procedure: Local Block
Outcome Measures: Primary outcome is efficacy of sensory anesthesia and analgesia;   Secondary outcome is patient perceived discomfort with block
16 Recruiting Efficacy of Breast Milk Expressed and Sucrose in Procedural Pain in Preterm
Conditions: Pain;   Premature Infant;   Human Milk;   Breastfeeding
Interventions: Other: expressed breast milk;   Behavioral: sucrose 24% oral
Outcome Measures: Pain neonatal;   Percentage of crying
17 Unknown  Index of Microcirculatory Resistance After Drug-Eluting Stent Implantation With High Dose Atorvastatin Loading
Condition: Acute Coronary Syndrome
Interventions: Drug: Pre-Procedural High dose atorvastatin loading;   Drug: No pre-Procedural high-dose atorvastatin loading
Outcome Measures: Index of microcirculatory resistance (IMR);   Major Adverse Cardiovascular Events (death, myocardial infarction, target vessel failure
18 Unknown  Safety and Efficacy of Propofol Only Sedation in Oral and Maxillofacial Surgery
Conditions: Procedural Sedation;   Propofol
Intervention: Drug: Propofol
Outcome Measures: Pre-Sedation Behavioral Sate;   Efficacy of Sedation;   Adverse outcome;   Adverse outcomes;   Patient Satisfaction;   Level of sedation;   Surgeon satisfaction
19 Recruiting Study to Find the Dose of Rapidly Administered Ketamine for Brief Painful Procedures in Children
Conditions: Abscess;   Fracture
Intervention: Drug: Ketamine
Outcome Measures: to find the mean effective dose (ED95)of ketamine;   adverse effects during Procedural sedation and after discharge
20 Recruiting Anti-inflammatory Effects of Colchicine in PCI
Condition: Coronary Artery Disease
Interventions: Drug: Colchicine;   Drug: Placebo
Outcome Measures: Post-Procedural IL-6 level;   Other relevant inflammatory markers;   30-day MACE;   post-Procedural myonecrosis