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Pulmonary fibrosis and Seretide

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Pulmonary Fibrosis Symptoms and Causes

Pulmonary fibrosis is a condition in which the tissue deep in your lungs becomes scarred over time. This tissue gets thick and stiff. That makes it hard for you to catch your breath, and your blood may not get enough oxygen.

Causes of pulmonary fibrosis include environmental pollutants, some medicines, some connective tissue diseases, and interstitial lung disease. Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. In most cases, the cause cannot be found. This is called idiopathic pulmonary fibrosis.

Symptoms include

  • Shortness of breath
  • A dry, hacking cough that doesn't get better
  • Fatigue
  • Weight loss for no known reason
  • Aching muscles and joints
  • Clubbing, which is the widening and rounding of the tips of the fingers or toes

Your doctor may use your medical history, imaging tests, a biopsy, and lung function tests to diagnose pulmonary fibrosis. There is no cure. Treatments can help with symptoms and improve your quality of life. They include medicines, oxygen therapy, pulmonary rehabilitation, or a lung transplant.

NIH: National Heart, Lung, and Blood Institute

Check out the latest treatments for pulmonary fibrosis

pulmonary fibrosis treatment research studies

Seretide clinical trials, surveys and public health registries


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Seretide Side Effects

Dyspnoea (293)
Asthma (266)
Death (247)
Cough (140)
Pneumonia (125)
Product Quality Issue (119)
Asthmatic Crisis (85)
Lower Respiratory Tract Infection (72)
Overdose (71)
Respiratory Failure (69)
Fatigue (62)
Chronic Obstructive Pulmonary Disease (61)
Chest Discomfort (61)
Dysphonia (56)
Adrenal Insufficiency (50)
Chest Pain (43)
Tachycardia (40)
Malaise (39)
Dizziness (37)
Headache (36)
Pain (35)
Pyrexia (35)
Condition Aggravated (33)
Cushing's Syndrome (33)
Asthenia (33)
Pruritus (31)
Hypertension (30)
Bronchitis (30)
Tremor (29)
Lung Neoplasm Malignant (29)
Convulsion (28)
Blood Cortisol Decreased (28)
Pulmonary Fibrosis (27)
Wheezing (26)
Myocardial Infarction (26)
Back Pain (26)
Nasopharyngitis (26)
Oedema Peripheral (26)
Pulmonary Embolism (24)
Emphysema (23)
Gait Disturbance (22)
Palpitations (22)
Osteonecrosis (22)
Productive Cough (22)
Bronchospasm (22)
Loss Of Consciousness (21)
Cardiac Failure (21)
Rash (20)
Infarction (20)
Infection (20)

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Common Meds

Abilify (10132)
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Amlodipine (6664)
Amoxicillin (4387)
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Doxycycline (1757)
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Recent Reviews

i had suffering asthma since abaut 15 years. but since use seretide inhaler i am feeling more better. but i am affraid seretide inhaler 125 mg for along time. now iam still breast feeding for my third baby. and also iam affraid also increase m

My father is suffrering from idiotypic Pulmonary Fibrosis. In medication he is taking Prednisone,Perfenodone and azathropine. he is now geeting bleeding from his nose.Can anybody inform me that this is just a side effect of any d

9 yr old son put on Seretide. Psychotic nightmares from day 2. Waking up very distressed. Shakes. fits. Saying 'Help me hlpe me please. I am going to die. Help me please. I am going to kill myself. Oh No. I died. Help me . Help me. There is

After taking Seretide, 9 yr old also complains of stuff stuck in the throat and finding it hard to breath. (As well as pyshcotic nightmares). A disaster of a drug for us. No problems when on flixotide.

After use of Seretide 5 months I get myocardii infarct. I am 63 old man, and I never be ill in past. *DONT_KNOW* *DONT_KNOW*

Been on Seretide for 4 years 125mg 1 puff per day just before bed. For 2.5 years I've been suffering with pain just below my left cage on the side of my torso, panic attacks started 2 years ago only to have been really bad earlier this week. I've jus

Breathing easier but acid indigestion and reflux. Cramp. I stopped taking the seretide evohaler and the terrible acid continued but got easier. The cramp has gone, thank goodness as one muscle would cramp one way and the other would cramp the other,

Developed Asthma after contacting a very bad chest infection. Was hospitalised and prescribed antibiotic and Seride 250 evohaler. Have since developed palpitations and my heart is definitely missing beats particularly when I am in bed. Also have deve

Gain weight

Has anyone noticed any behavioural or mood changes with the use of seretide? My 6 year old son uses it and, following his asthma plan, we increased his dosage from 1 puff morning and night to 2 and he has been very prone to crying, throwing tantrums,

My father is suffrering from idiotypic Pulmonary Fibrosis. In medication he is taking Prednisone,Perfenodone and azathropine. he is now geeting bleeding from his nose.Can anybody inform me that this is just a side effect of any d

<span style='color: #808080;'>&iquest;En qu&eacute; est&aacute;s pensando...?I'm a Spanish teenagerpatient of Cystic Fibrosis but I've never been very affected by the illness. In fact, I have quite normal living standards

After being discharged from eER I saw in my file that the doppler impression shows mild tricuspid regurgitation and mild pulmonary hypertension =-O scared should I be worried

After taking cabaser for 4 years for restless legs . I found outI had to have two heart valves replaced my mitral and my aorta valves and also I havefibrosis of the lungs . My heart specialist has put it down to taking cabaser , t

Completed course of interferon and ribavirn for Hepititis C. Fell pregnant 5 months after completion of treatment and gave birth to a baby boy weighing 7.6 lbs. He has Trisomy 21. He was born with Persisitant Pulmonary hypertension and a VSD. I do no

Female 39 years old from Denmark. Was treated with Octostim as a test. After drug was administred i experience this: <span style='font-weight: bold;'><a href='http://sideeffects101.com/drug-side-effects/o/octostim-pulmonary-oedema.htm' rel='

Had RhoGAM after childirth in 1972 and 1975. In 1992 I was diagnosed with hepatitis C. I now have stage 3 liver fibrosis and inflammation. I went through interferon-ribavirin treatment for hepatitis C recently, but did n

Has any one found legal representation willing to pursue pulmonary embolis caused by avandia

Having suffered 3 dvt's, 1 pulmonary embolism, 1 stroke and 2 tis's, I was given Fragmin. I previously had been taking warfarin for about 20 yrs, this ceased to work. I am now told that I have Osteoporosis... I seem to remember along the way that

Hello my nice has cystic fibrosis and is on Ceftazidine and Tobramyacin . She asked me to help her and since i practice shamanism. I Am searching for knowledge on the side effects for such western medicine. Thanks for your time. Uncle Bob.

Pulmonary Fibrosis Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  An Investigation of the Mechanism of Action of Seretide in Chronic Obstructive Pulmonary Disease
Condition: Chronic Obstructive Pulmonary Disease
Intervention: Drug: Seretide 500 Accuhaler
Outcome Measures: The primary outcome measures are change in cell type and activation status;   Change in sputum and serum cytokines Change in bacterial colonization
2 Not yet recruiting A Randomized Comparative Effectiveness Research Trial of Three Treatments for COPD Patients
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Salbutamol (Ventolin®);   Drug: Formoterol (Oxis Turbuhaler®);   Drug: Salmeterol / fluticasone (Seretide®);   Drug: Bufei granule;   Drug: Bufeijianpi granule;   Drug: Bufeiyishen granule;   Drug: Yiqizishen granule;   Drug: conventional medicine + TCM
Outcome Measures: the frequency of exacerbation;   Forced expiratory volume in one second;   Dyspnea;   6 Minutes Walking Distance Test(6MWD);   Quality of life;   Economic Evaluation
3 Recruiting Individualized Dosing Schedule of Inhaled Bronchodilator for Endotracheally Intubated COPD Patients
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: salmeterol/fluticasone;   Drug: ipatropium/salbutamol;   Drug: Methylprednisolone;   Drug: Additional broncho-dilators inhalation;   Other: Determining personal target airway resistance;   Device: Ventilator support
Outcome Measures: ∆Raw (the difference between measured and target airway resistance);   Rapidity of ∆Raw change;   number of ventilator-free days from day 1 to 28;   Percentage of breathing without assistance by day 28;   number of episode of nosocomial pneumonia;   Number of total puff of rescue short-acting bronchodilator;   number of drug-related adverse effect;   Mortality rate
4 Recruiting Comparison of Indacaterol 150 μg Once Daily (o.d.) With Salmeterol/Fluticasone Propionate 50 μg/500 μg Twice Daily (b.i.d.)
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: Indacaterol;   Drug: Salmeterol
Outcome Measures: Trough forced expiratory volume in one second (FEV1) at 12 weeks;   Trough FEV1;   FEV1;   FVC;   Standardized AUC (5min-4h) for FEV1;   Transition Dyspnea Index;   COPD Exacerbations;   Mean daily rescue medication use;   Percentage of days with no rescue medication use;   St Georges Respiratory Questionnaire for COPD;   Adverse event data;   ECG;   Vital signs;   Biochemistry, haematology, urinalysis data
5 Unknown  Comparing Treatment Efficacy With HD/MD Flu Plus Sal in Chronic Obstructive Pulmonary Disease (COPD) Patients
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Drug: fluticasone/ salmeterol 125/25 mcg/puff;   Drug: fluticasone/ salmeterol 250/25 mcg/puff
Outcome Measures: The change of lung function parameters(FEV1&FVC) at different time points;   Annual rate of acute exacerbations;   Life quality evaluation;   Annual incidence of community-acquired pneumonia
6 Unknown  Efficacy and Safety Study of Formoterol/Fluticasone and Salmeterol/Fluticasone in Patients With Moderate-to-severe COPD
Conditions: Chronic Obstructive Pulmonary Disease;   COPD
Interventions: Drug: Combination Fluticasone /Formoterol 12/250 μg;   Drug: Seretide Diskus (salmeterol/fluticasone) 50/250 μg
Outcome Measures: Changes in pre-bronchodilator forced expiratory volume in first second (FEV1);   Changes in forced expiratory volume in first second, without bronchodilator;   Safety descriptive about occurence of adverse events, evaluation of results of clinical/physical examination and laboratory tests results;   Changes in COPD Assessment Test (CAT)
7 Recruiting Study of Aclidinium Bromide/Formoterol Fumarate Compared With Salmeterol/Fluticasone Propionate in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Aclidinium Bromide / Formoterol Fumarate;   Drug: Salmeterol / Fluticasone
Outcome Measures: Peak forced expiratory volume in one second (FEV1) at week 24;   Transition Dyspnoea Index (TDI) focal score at week 24
8 Not yet recruiting Long-Term Safety Evaluation of Dupilumab in Patients With Asthma
Condition: Asthma
Interventions: Drug: dupilumab SAR231893 (REGN668);   Drug: fluticasone propionate and salmeterol;   Drug: budesonide and formoterol;   Drug: mometasone furoate and formoterol
Outcome Measures: Number of participants with adverse events;   Assessment of safety parameters (laboratory data, electrocardiogram and vital signs) - clinically significant changes from baseline;   Forced expiratory volume in one second - clinically significant changes from baseline;   Asthma control questionnaire - clinically significant changes from baseline;   Asthma symptom scores - clinically significant changes from baseline;   Asthma Quality of Life Questionnaire (AQLQS) - clinically significant changes from baseline;   Anti-drug antibodies - changes from baseline;   Biomarkers - changes from baseline
9 Recruiting Stepping Down of Asthma Medication in Controlled Asthma
Condition: Asthma
Intervention: Drug: Asthma medication reduction
Outcome Measures: Asthma exacerbation;   The proportion of asthma patients able to reduce their medication
10 Unknown  The Efficacy and Safety of Salmeterol/Fluticasone Propionate vs Atropium/Albuterol in Patients COPD
Condition: Chronic Obstructive Pulmonary Disease (COPD)
Intervention: Drug: Salmeterol/Fluticasone Propionate
Outcome Measures: pre-broncholidator FEV1;   post-broncholidator FEV1;   Morning PEF, inspiration capacity (IC) and Residual Volume (RV);   Overall daytime symptom score, reliever medication use,SGRQ and BODY index;   Percent of symptom-free nights, sleep symptoms, nighttime awakenings due to respiratory symptoms;   Biomarkers: serum Clara cell 16 (CC-16) protein and serum surfactant protein D (SPD);   participants with adverse events and COPD exacerbations
11 Not yet recruiting Beta Blocker Therapy in Moderate to Severe COPD
Condition: Chronic Obstructive Pulmonary Disease
Interventions: Biological: Carvedilol;   Biological: Bisoprolol;   Biological: Beclometasone/formoterol;   Biological: Tiotropium;   Biological: Beclometasone
Outcome Measures: Change in airway resistance at 5HZ (R5) using impulse oscillometry from baseline.;   Change in remaining impulse oscillometry measurements from baseline;   Change in spirometry measurements from baseline;   Change in echocardiogram parameters from baseline;   Change in vital signs from baseline;   Change in six minute walk test distance from baseline;   Change in St George's Respiratory Questionnaire score from baseline