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Rosacea and Doxycycline

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Rosacea Symptoms and Causes

Rosacea is a long-term disease that affects your skin and sometimes your eyes. It causes redness and pimples. Rosacea is most common in women and people with fair skin. It most often affects middle-aged and older adults.

In most cases, Rosacea only affects the face. Symptoms can include

  • Frequent redness of the face, or flushing
  • Small, red lines under the skin
  • Acne
  • A swollen nose
  • Thick skin, usually on the forehead, chin, and cheeks
  • Red, dry, itchy eyes and sometimes vision problems

No one knows what causes Rosacea. You may be more likely to have it if you blush a lot or if Rosacea runs in your family. Rosacea is not dangerous. There is no cure, but treatments can help. They include medicines and sometimes surgery.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for rosacea

rosacea treatment research studies

Doxycycline clinical trials, surveys and public health registries


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Doxycycline Side Effects

Headache (186)
Nausea (176)
Rash (131)
Dizziness (126)
Vomiting (125)
Dyspnoea (125)
Pain (125)
Haemorrhage (116)
Malaise (114)
Diarrhoea (111)
Oesophageal Ulcer (100)
Pyrexia (97)
Fatigue (95)
Chest Pain (95)
Anxiety (94)
Pruritus (92)
Abortion Incomplete (91)
Photosensitivity Reaction (88)
Asthenia (82)
Abdominal Pain Upper (71)
Depression (41)
Abdominal Pain (40)
Anaemia (38)
Stevens-johnson Syndrome (35)
Suicidal Ideation (34)
Muscle Spasms (32)
Confusional State (32)
Vision Blurred (31)
Oesophagitis (31)
Oedema Peripheral (31)
Dyspepsia (30)
Hypotension (30)
Pancreatitis (30)
Syncope (30)
Benign Intracranial Hypertension (29)
Paraesthesia (28)
Palpitations (28)
Arthralgia (27)
Erythema (27)
Visual Impairment (27)
Intracranial Pressure Increased (27)
Pulmonary Embolism (27)
Dysphagia (26)
Blister (26)
Abdominal Discomfort (25)
Pancreatitis Acute (25)
Renal Failure Acute (25)
Panic Attack (25)
Hypersensitivity (24)
Swollen Tongue (24)

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Recent Reviews

I am 11 days into a 20 day regime of Doxycycline for Staph. I am 51 and have not had a period in 2 years. 2 days ago I had some breast tenderness and this morning I woke to classic menstrual bleeding with abdominal cramps. Could the Doxycyclin

I am a 45 year old women who developed acne 4 years agao after my hysterectomy.Ihave been using doxycycline for the last 10 months......the only side effects I have experienced are nausea if pill tkn in empty stomach and weight gain ( which

I am anaemic and i've been treating my acne with doxycycline but instead my anaemia got worse i'm drowzy,my head feels heavy and i have a headache from hell.

I had these 100mg tablets for a sinus infection its gone now i take the last 1 tomorrow but after the few few days on them i ad to take 8 2 to start with then 1 a day. so after a few days on them i got 2 complaints my anus was a bit sore and neck an

I have been using Prosacea gel since Sunday evening. This morning, I starting itching at my jawliine on the left side and it moved over to the right side. Is this a side effect?

I have just taken myself off Doxycycline. I had so much pressure in my skull - unable to stand for very long, felt really weak and thought I was going to pass out..A Few pains in my kidney area.

I have Rosacea and just started using Prosacea topical cream yesterday. My eyes are burning a little and I was wondering if that was a side effect or am I just tired?

I took doxycycline for 10 days for perioral dermatitis. A week after completing the medicine I went to the ER with a burning in my chest. Then I lost my appetite, was nauseousand started losing weight. Three weeks later I was diagnosed with

I was taking doxycycline for an MRSA staph infection. I had tightness in my chest and worsening difficulty breathing, sore tongue, burning palms and soles of my feet, and extreme exhaustion. At the end of my 9th day on the medication, I had excruti

I was taking doxycycline for meibomitis and a little over 2 weeks after I started I came ill with severe head pressure,tinnitus,chills,nausea,flulike symptoms and after 2 emergency room visits and 6 different doctors (who were trying to treat me for

Acne or rosacea affecting the nose 8-)

I have Rosacea and just started using Prosacea topical cream yesterday. My eyes are burning a little and I was wondering if that was a side effect or am I just tired?

I was on Oracea for 18 months for Rosacea and have been diagnosed with Colitis. I am now on Flagyl for one week and it has helped . I am not able to take Oracea anymore

Im only 14. I think I have rosacea I probably do. But what kind of guy wants a girl like this? My favorite food is hot cheetos and coffee. I wash my face everynight and I do wear make up. But all my friends hardly wear it and I dont like to wear it.

Same here. It made my rosacea worse (and more veins, even scars)

While taking Arimidex for breast cancer, has anyone developed rosacea?

Rosacea Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Photodynamic Therapy for Papulopustular Rosacea
Conditions: Rosacea;   Papulopustular Rosacea
Interventions: Drug: Aminolevulinic acid topical solution 20%;   Device: Blu-U Light Therapy
Outcome Measures: Improvement of the inflammatory lesions (papules, pustules, nodules), erythema, and telangiectasia of Rosacea as assessed by the Investigator's Global Assessment (IGA);   Improvement of the inflammatory lesions (papules, pustules, nodules) of Rosacea as assessed by the Inflammatory Lesion Investigator's Global Assessment (ILIGA);   Evaluate improvement of Rosacea associated erythema as assessed by the Clinical Erythema Assessment (CEA) scale;   Evaluate improvement of the inflammatory lesions (papules, pustules, nodules) of Rosacea as measured by a difference in inflammatory lesion count;   Evaluate improvement of Rosacea as assessed by the Patient Overall Assessment Scale
2 Recruiting A Study to Evaluate the Safety and Clinical Study of Azelaic Acid Gel 15% in Patients With Moderate Facial Rosacea
Condition: Rosacea
Intervention: Drug: Azelaic acid
Outcome Measures: The primary endpoint is the percent change from baseline to Week 12 in the inflammatory (papules and pustules) lesion counts.;   The proportion of subjects with a clinical respsoense of "success" at Week 12 using Investigator Global Evaluation (IGE)
3 Recruiting An Analysis of the Effect of Topical Cromolyn Sodium on Rosacea-associated Erythema
Condition: Papulopustular Rosacea
Interventions: Drug: Cromolyn Sodium;   Drug: Normal Saline
Outcome Measures: Facial erythema;   Change in facial erythema;   Matrix Metalloproteinase levels;   Change in matrix metalloproteinase levels
4 Recruiting Intense Pulsed Light (IPL) and Meibomian Gland Expression to Treat Ocular Rosacea Secondary to Inactive Chronic Ocular GVHD
Conditions: GVHD;   Ocular Rosacea
Intervention: Device: IPL
Outcome Measures: Number of participants who respond to IPL;   Number of participants who experience adverse events
5 Recruiting Ultherapy® for the Treatment of Erythematotelangiectatic Rosacea
Conditions: Erythematotelangiectatic Rosacea;   Rosacea
Intervention: Device: Ulthera System Treatment
Outcome Measures: Clinician Erythema Assessment at 90 days post-treatment compared to baseline;   CEA scale at 180 days post-treatment compared to baseline.;   CEA scale at 365 days post-treatment compared to baseline.;   Patient Self-Assessment (PSA) of erythema at 90 Days compared to baseline.;   Patient Self-Assessment (PSA) of erythema at 180 Days compared to baseline.;   Patient Self-Assessment (PSA) of erythema at 365 Days compared to baseline.;   Dermatology Life Quality Index (DLQI) Assessment at 90 Days post-treatment;   Dermatology Life Quality Index (DLQI) Assessment at 180 Days post-treatment;   Dermatology Life Quality Index (DLQI) Assessment at 365 Days post-treatment;   Colorimeter at 90 Days post-treatment;   Colorimeter at 180 Days post-treatment;   Colorimeter at 365 Days post-treatment
6 Not yet recruiting Safety and Efficacy of AGN-199201 in Patients With Persistent Erythema Associated With Rosacea
Conditions: Erythema;   Rosacea
Interventions: Drug: AGN-199201;   Drug: Vehicle to AGN-199201
Outcome Measures: Percentage of Participants with at Least a 2-Grade Decrease from Baseline on Both Clinician Erythema Assessment (CEA) and Subject Satisfaction Assessment (SSA) 5-point Scales;   Percentage of Participants with at Least a 2-Grade Decrease from Baseline on SSA Using a 5-Point Scale;   Change from Baseline in Rosacea Facial Redness as Measured by Digital Imaging Analysis (DIA);   Satisfaction Assessment for Rosacea Facial Redness Using a 5-Point Scale;   Symptom Assessment for Rosacea Facial Redness (Skin Sensation Domain Score) Using a 5-Point Scale;   Percentage of Participants with at Least a 1-Grade Decrease from Baseline on SSA Using a 5-Point Scale
7 Not yet recruiting Efficacy and Safety of AGN-199201 in Patients With Persistent Erythema Associated With Rosacea
Conditions: Erythema;   Rosacea
Interventions: Drug: AGN-199201;   Drug: Vehicle to AGN-199201
Outcome Measures: Percentage of Participants with at Least a 2-Grade Decrease from Baseline on Both Clinician Erythema Assessment (CEA) and Subject Satisfaction Assessment (SSA) 5-point Scales;   Percentage of Participants with at Least a 2-Grade Decrease from Baseline on SSA Using a 5-Point Scale;   Change from Baseline in Rosacea Facial Redness as Measured by Digital Imaging Analysis (DIA);   Satisfaction Assessment for Rosacea Facial Redness Using a 5-Point Scale;   Symptom Assessment for Rosacea Facial Redness (Skin Sensation Domain Score) Using a 5-Point Scale;   Percentage of Participants with at Least a 1-Grade Decrease from Baseline on SSA Using a 5-Point Scale
8 Recruiting Finacea 15% and Brimonidine 0.33% Gel in the Treatment of Rosacea - A Pilot Study
Condition: Acne Rosacea
Interventions: Drug: Azelaic acid 15%;   Drug: Brimonidine 0.33%
Outcome Measures: Change in Investigator Global Assessment;   Lesion counts;   Clinician's Erythema assessment;   Erythema VAS Assessment (Subject);   Dermatology Life Quality Index (DLQI)
9 Not yet recruiting A Long-Term Safety and Efficacy Study of AGN-199201 in Patients With Persistent Erythema Associated With Rosacea
Conditions: Erythema;   Rosacea
Intervention: Drug: AGN-199201
Outcome Measures: Percentage of Participants with Treatment-Related Adverse Events;   Percentage of Participants with at Least a 2-Grade Decrease from Baseline on Both Clinician Erythema Assessment (CEA) and Subject Satisfaction Assessment (SSA) Using 5-Point Scales
10 Recruiting Potential Research Study Participant Registry
Conditions: Acne;   Actinic Keratosis;   Dysplastic Nevi;   Eczema;   Psoriasis;   Skin Cancer;   Rosacea;   Leg Ulcers;   Foot Ulcers;   Atopic Dermatitis
Intervention:
Outcome Measure: Identify Dermatology Clinical research topics of interest in the community.
11 Not yet recruiting Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis
Conditions: Demodex;   Demodicidosis;   Topical Ivermectin
Intervention: Drug: ivermectin cream 0.5%
Outcome Measures: A decrease in mite density in skin surface biopsy after treatment with topical ivermectin (≤5 mites/cm2 for skin lesions).;   Clinical improvement;   A comparable dermoscopic improvement in the demodicidosis features
12 Recruiting Efficacy of Pulsed Light Therapy for Meibomian Gland Dysfunction and Dry Eye Syndrome
Conditions: Meibomian Gland Dysfunction;   Dry Eye Syndrome
Interventions: Device: Cutera Xeo Platform-Limelight;   Device: Sciton BroadBand Light
Outcome Measure: Anatomical improvement of the meibomian glands and their secretions.
13 Not yet recruiting Intralesional Tetracycline Injection in the Treatment of Chalazia
Conditions: Chalazia;   Chalazion
Intervention: Drug: Tetracycline
Outcome Measure: Lesion size