Soft tissue disorder and Fascia


Soft Tissue Disorder Symptoms and Causes

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

  • Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
  • Autoimmune disorders, such as lupus and scleroderma
  • Cancers, like some types of soft tissue sarcoma

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Check out the latest treatments for soft tissue disorder

soft tissue disorder treatment research studies

Fascia clinical trials, surveys and public health registries

Find Drug Side Effect reports

Fascia Side Effects

Vaginal Infection (8)
Graft Infection (8)
Urinary Tract Infection (2)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)

Recent Reviews

I have been put on Molipaxin 3 weeks ago, I have dry mouth, hair loss and my panic attacks were showing no signs of improvement. Dr increased it to 100mg and put me onto Lamictin. I am not bi polar nor epileptic. My disorder ist algora phoebia. I a

Had complete hysterectomy in 1999 and developed cystis acne. Was 34 at the time. Prescribed accutane for 9 months. Worked great with the usual side effects-dry lips. Now 11 years later, I am suffering from a severe anxiety disorder with body dimorph

Endosulfan can causes genetic disorder,body disability, impotency in Male & Female both.. So be careful say no to Endosulfan & other pesticides

I received an injection close to my shoulder blade June 16, 2010. Three months later, I have an indentation and my health care provider has indicated that perhaps the muscle has scare tissue and the indentation and disc

I took Champix in March of '08 and I am still suffering from most of the side effects of this poisonous drug. To name a few Psychosis NOS, Major Depressive Disorder, suicidal, Emotional instability, agression, rage, Somatoform Di

I was diagnosed with hypothyroidism about 2 years ago. I have been prescribed just about every brand of medication for my disorder and have never successfully gotten my symptoms under control, even with some of the more

<span style='color: #808080;'><b>Describe Your Schizophrenia from HPV (GARDASIL) 2007 Experience Here:My 15 year old sonjust received first vaccination for HPV, nine days later experienced a psychotic disorder for one week, now

<span style='font-weight: bold;'><a href='' rel='nofollow'>cardiac disorder</a>, <a href='' r

A doctor subscribed this medication to me for a flu. On the 3rd day I had soft tissue blisters in my nose and my nose was swollen. Also my glands under my neck/jaw were sore. The 4th day my checks and jaws also swole up. *DONT_KNOW*

A friend was given a Vivitrol shot a month ago and go an abcess at the site, was treated with antibiotics to no avail... went to emergency room ended up in surgury with lots of necrotic tissue. will be on IV antibiotics and in home wound ca

Soft Tissue Disorder Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Radial Extracorporeal Shock Wave Treatment (rESWT) of Myofascial Pain Syndrome in Low Back Pain
Conditions: Myofascial Pain Syndromes;   Myofascial Trigger Point;   Low Back Pain;   Lumbago
Interventions: Device: Radial Extracorporeal Shock Wave;   Device: Placebo
Outcome Measure: Evidence of pain relief by visual analogue scale (VAS) of radial extracorporeal shock waves in Myofascial pain syndrome in the lumbar and gluteal region compared to placebo
2 Unknown  Dose Response Effects of Cervical Spinal Manipulative Therapy (SMT) on Pressure Sensitivity of Myofascial Trigger Points
Conditions: Trigger Points, Myofascial;   Myofascial Trigger Points;   Myofascial Pain Syndrome
Intervention: Other: cervical spinal manipulative therapy
Outcome Measures: Change scores of the pressure algometry;   The perception by subjects as to whether they received a real treatment
3 Unknown  Traditional Acupuncture and Myofascial Trigger Point Dry Needling and Acupressure for Chronic Low Back Pain
Condition: Low Back Pain
Interventions: Procedure: Traditional needle acupuncture;   Procedure: Myofascial trigger point dry needling;   Procedure: Myofascial trigger point acupressure
Outcome Measure:
4 Unknown  Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome
Conditions: Cervicobrachial Neuralgia;   Myofascial Pain Syndromes
Intervention: Drug: Botulinum toxin serotype A
Outcome Measures: Numerical pain rating;   Brief Pain Inventory;   Neck Disability Index;   Cervical range of motion;   Number of trigger points;   Postural exam;   Pain Diary and medications use;   Short Form (SF)-36
5 Not yet recruiting Injection With OnabotulinumtoxinA (Botox) for the Treatment of Chronic Pelvic Pain
Conditions: Myofascial Pain Syndromes;   Myofascial Trigger Point Pain;   Trigger Point Pain, Myofascial
Interventions: Drug: OnabotulinumtoxinA;   Drug: Placebo
Outcome Measures: efficacy;   Duration of effect;   quality of life;   bladder/bowel/sexual functions;   complications of therapy
6 Unknown  Effects of Myofascial Release on Pain, Disability and Electromyography of Erector Spinae in Chronic Low Back Pain
Conditions: Low Back Pain;   Disability;   Motor Activity;   Range of Motion
Interventions: Other: Myofascial treatment;   Other: Placebo
Outcome Measures: Lumbar Pain;   Disability;   Fear Avoidance Beliefs;   EMG Erector Spinae;   Lumbar ROM
7 Recruiting Using Saline for Myofascial Pain Syndromes (USAMPS)
Condition: Myofascial Pain Syndrome
Interventions: Drug: Lidocaine;   Drug: Triamcinolone Acetonide;   Drug: Saline
Outcome Measures: Change of Pain Intensity before and at two weeks after treatment;   Duration of Pain;   Change of Pain Intensity before and 2 - 5 minutes after treatment
8 Not yet recruiting Diagnosis and Management of Myofascial Pain Syndrome in Women With Mastectomies
Conditions: Breast Cancer;   Myofascial Trigger Point
Interventions: Other: Kinesiotherapy;   Other: Isquemic compression;   Other: High voltage electrical stimulation
Outcome Measures: Pain;   Quality of life;   Skin Temperature;   Posture
9 Not yet recruiting Effectiveness of Physical Therapy Treatments of Myofascial Trigger Points in Subjects With Neck Pain
Conditions: Neck Pain;   Myofascial Pain Syndrome
Interventions: Other: Kinesiotherapy;   Other: Ultrasound;   Other: Diadynamic currents
Outcome Measures: Pain;   Cervical range of motion;   Skin temperature;   Muscle activity
10 Not yet recruiting Radial Shock Wave and Acupuncture for Myofascial Pain
Condition: Myofascial Pain
Interventions: Device: Radial shock wave;   Device: Acupuncture
Outcome Measures: VAS for pain;   Pain threshold;   neck disability index;   patient global assessment
11 Recruiting Multicenter Randomized Double-blind Study Evaluating the Effects of Botulinum Toxin A Associated With ropivacaïne Versus ropivacaïne Alone in the Treatment of the Myofascial Pelviperineal Pain
Condition: Myofascial Pelviperineal Pain
Interventions: Drug: botulinum toxin A + ropivacaïne;   Drug: Ropivacaïne
Outcome Measures: Evolution of the PGI-I (Patient Global Impression of Improvement);   Evaluation of pain on digital scale (EN);   To assess the changing parameters of quality of life: global improvement score / treatment satisfaction assessed by digital scale, international pain scales (MPI, QDSA, QCD) / Beck and HAD score;   To assess the evolution of analgesics consumption (score MQS)
12 Unknown  Efficacy of Botulinum Toxin Versus Lidocaine in Treating Masticatory Myofascial Face Pain Using Ultrasound and EMG Guided Techniques
Condition: Face Pain
Interventions: Drug: lidocaine;   Drug: chemodenercation
Outcome Measure: clinical response
13 Not yet recruiting Botox for Treatment of TMJ Disorder With Bruxism
Conditions: Temporomandibular Joint Disorders;   Bruxism;   Temporomandibular Joint Dysfunction Syndrome;   Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint
Intervention: Drug: onabotulinumtoxinA
Outcome Measures: 50% reduction in pain;   25% increase in maximal opening at incisors
14 Recruiting Botulinum Toxin Type A Versus Saline Trigger Point Injections for Myofascial Pelvic Pain
Condition: Myofascial Pelvic Pain
Interventions: Drug: Intervention-Botulinum Toxin Type A;   Drug: placebo
Outcome Measures: To evaluate the change in patient-reported pelvic pain following pelvic floor injections of 200 units of Botox compared with 20cc of normal saline.;   To evaluate the change in patient-reported pelvic pain following Botox injections in conjunction with pelvic floor physical therapy compared to saline injections with physical therapy.
15 Recruiting Effects of Thai Massage on Patients With Wrist Extensor Muscles Latent Myofascial Trigger Points
Condition: Patients With Latent Myofascial Trigger Point
Intervention: Other: Thai massage
Outcome Measures: Pressure Pain Threshold as a measure by algometry;   Pain scores on visual analog scale;   Wrist Range of motion as a Measure by goniometer;   Grip strength as a measure by hand-held dynamometer;   Patient satisfaction level
16 Recruiting rTMS Effects in the Neuromodulation and Pain Threshold of Chronic Myofascial Pain Patients
Condition: Chronic Pain
Interventions: Device: rTMS;   Device: Sham rTMS
Outcome Measures: Pain threshold;   Cortical excitability parameters (MEP, ICF, CSP and SICI)
17 Recruiting Interstitial Cystitis: Elucidation of the Psychophysiologic and Autonomic Characteristics (ICEPAC) Study
Conditions: Interstitial Cystitis/Painful Bladder Syndrome;   Myofascial Pelvic Pain
Intervention: Drug: Bupivacaine
Outcome Measures: Interstitial Cystitis;   Myofascial Pelvic Pain;   Depression Symptoms;   Stress Symptoms
18 Unknown  Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel
Conditions: Muscular Atrophy;   Sprains;   Tendonitis
Interventions: Drug: Ibuprofen;   Drug: Profenid
Outcome Measures: Clinical study evaluating the efficacy and safety of Ibuprofen 50mg / g gel in the treatment of patients with muscle pain, joint, or pain caused by sprains, contusions, tendinitis, or Myofascial compared to Profenid ® 25mg / g gel. ";   Clinical study evaluating the tolerability of Ibuprofen 50mg / g gel in the treatment of patients with muscle pain, joint, or pain caused by sprains, contusions, tendinitis, or Myofascial compared to Profenid ® 25mg / g gel. "
19 Recruiting Paraspinal Stimulation in Treating MPS
Condition: Clinical Study - RCT
Intervention: Procedure: DIMMST
Outcome Measures: Pain severity;   Pain threshold;   Sleep quality - how did you feel when you woke up;   Sleep quality - compared to your habitual sleep;   Sleep quality -last night
20 Unknown  Massage of the Low Back Muscles Assessed With Ultrasound Scanning
Condition: Myofascial Pain Syndrome
Interventions: Procedure: Specific massage for fascial release;   Other: Quiet non-instructed rest for 3 minutes
Outcome Measure: Thickness of lumbodorsal fascia determined by ultrasound imaging