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Therapeutic and Chloraprep

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Therapeutic Symptoms and Causes

What is cholesterol?

Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries and narrow or even block them. This puts you at risk for coronary artery disease and other heart diseases.

There are two main types of cholesterol. LDL is the "bad" cholesterol. A high LDL level leads to a buildup of cholesterol in your arteries. HDL is the "good" cholesterol. It carries cholesterol from other parts of your body back to your liver. Then your liver removes the cholesterol from your body.

What are the treatments for high cholesterol?

The treatments for high cholesterol are heart-healthy lifestyle changes and medicines. The lifestyle changes include healthy eating, weight management, and regular physical activity.

How can I lower cholesterol with diet?

Heart-healthy lifestyle changes include a diet to lower your cholesterol. The DASH eating plan is one example. Another is the Therapeutic Lifestyle Changes diet, which recommends that you

Choose healthier fats.You should limit both total fat and saturated fat. No more than 25 to 35 percent of your daily calories should come from dietary fats, and less than 7 percent of your daily calories should come from saturated fat. Depending upon how many calories you eat per day, here are the maximum amounts of fats that you should eat:

Calories per DayTotal FatSaturated Fat1,50042-58 grams10 grams2,00056-78 grams13 grams2,50069-97 grams17 grams

Saturated fat is a bad fat because it raises your LDL (bad cholesterol) level more than anything else in your diet. It is found in some meats, dairy products, chocolate, baked goods, and deep-fried and processed foods.

Trans fat is another bad fat; it can raise your LDL and lower you HDL (good cholesterol). Trans fat is mostly in foods made with hydrogenated oils and fats, such as stick margarine, crackers, and french fries.

Instead of these bad fats, try healthier fats, such as lean meat, nuts, and unsaturated oils like canola, olive, and safflower oils.

Limit foods with cholesterol. If you are trying to lower your cholesterol, you should have less than 200 mg a day of cholesterol. Cholesterol is in foods of animal origin, such as liver and other organ meats, egg yolks, shrimp, and whole milk dairy products.

Eat plenty of soluble fiber. Foods high in soluble fiber help prevent your digestive tract from absorbing cholesterol. These foods include

  • Whole-grain cereals such as oatmeal and oat bran
  • Fruits such as apples, bananas, oranges, pears, and prunes
  • Legumes such as kidney beans, lentils, chick peas, black-eyed peas, and lima beans

Eat lots of fruits and vegetables. A diet rich in fruits and vegetables can increase important cholesterol-lowering compounds in your diet. These compounds, called plant stanols or sterols, work like soluble fiber.

Eat fish that are high in omega-3 fatty acids. These acids won't lower your LDL level, but they may help raise your HDL level. They may also protect your heart from blood clots and inflammation and reduce your risk of heart attack. Fish that are a good source of omega-3 fatty acids include salmon, tuna (canned or fresh), and mackerel. Try to eat these fish two times a week.

Limit salt. You should try to limit the amount of sodium (salt) that you eat to no more than 2,300 milligrams (about 1 teaspoon of salt) a day. That includes all the sodium you eat, whether it was added in cooking or at the table, or already present in food products. Limiting salt won't lower your cholesterol, but it can lower your risk of heart diseases by helping to lower your blood pressure. You can reduce your sodium by instead choosing low-salt and "no added salt" foods and seasonings at the table or while cooking.

Limit alcohol. Alcohol adds extra calories, which can lead to weight gain. Being overweight can raise your LDL level and lower your HDL level. Too much alcohol can also increase your risk of heart diseases because it can raise your blood pressure and triglyceride level. One drink is a glass of wine, beer, or a small amount of hard liquor, and the recommendation is that

  • Men should have no more than two drinks containing alcohol a day
  • Women should have no more than one drink containing alcohol a day

Nutrition labels can help you figure out how much fat, saturated fat, cholesterol, fiber, and sodium is in the foods that you buy.

NIH: National Heart, Lung, and Blood Institute

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Chloraprep Side Effects

Skin Irritation (75)
Application Site Rash (39)
Rash (23)
Blister (19)
Erythema (17)
Anaphylactic Reaction (17)
Pruritus (16)
Application Site Reaction (13)
Application Site Erythema (13)
Application Site Pruritus (12)
Procedural Complication (12)
Burns Second Degree (11)
Scratch (8)
Application Site Vesicles (8)
Thermal Burn (8)
Burns First Degree (8)
Rash Papular (8)
Scab (7)
Chemical Injury (7)
Post Procedural Infection (6)
Caustic Injury (5)
Accidental Exposure (5)
Application Site Burn (5)
Staphylococcal Infection (5)
Rash Pruritic (5)
Rash Erythematous (5)
Chemical Burn Of Skin (4)
Application Site Scar (3)
Application Site Pain (3)
Bacterial Infection (3)
Culture Positive (3)
Dermatitis Contact (3)
Feeling Abnormal (3)
Condition Aggravated (3)
Burning Sensation (3)
Excoriation (3)
Pathogen Resistance (3)
Hypersensitivity (3)
Laceration (3)
Post Procedural Complication (3)
Lip Swelling (3)
Postoperative Wound Infection (3)
Swollen Tongue (3)
Swelling (3)
Lymphoma (2)
Injury (2)
Nausea (2)
Oropharyngeal Pain (2)
Pharyngeal Oedema (2)
No Therapeutic Response (2)

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Recent Reviews

03/03/11 I had a fibroid tumor removed on my left palm. Choloaprep was used and where the liquid drained down the wrist and was dropped a couple of places on my left thigh there was severe contact dermititis. It was 6 wks and 2 courses of cortisone b

1 week after my liver biopsy, I developed a beefy red, hot, inflamed, tense, swollen, painful, itchy rash on the area where the chloraprep was used on over 80% of my abdomen. 3 weeks later, the rash is still red, but dry and peeling. Some areas look

After my beast biopsy in 7/11, I experienced a severe rash with raised bumps blistering that manifested 3 to 4 days after the biopsy. The itching was unbearable. At first I thought it was the surgical tape but then it started to spread over my entire

Are you still having problems or have they resolved. Also, do you have any sensitivity to the sun since this occured?

Day 9 post op of being swabbed with chloraprep, rash, swelling of neck, face and lips, 1 day of benadryl and then 6 days of prednizone. Day 1 today after prednisone and rash is popping back out justa s red and angry as day 1 but no swelling

Had a needle biopsy for my thyroid on Monday. On Friday I got a Celestone shot for the horrible reaction to Chloraprep. I know I'm allergic to all tapes, latex, etc, so the only culprit was the Chloraprep. It got worse instead of resolving, to the

Had a stent put in. Chloroprep on stomach below belly button down to thigh creases and down right thigh for incision. Was shaved and chloroprep was applied between my thighs and to my lady parts. No problem until I came home 2 days after surgery a

Had colon surgery Feb. 1, 2011. My entire torso was inflamed...burning and itching. I couldn't stand for anything to touch me. This was much more painful than my surgery. For days afterwards, heat and clothing caused this to flare up and burn and itc

Had knee arthroscopy on September 22nd and am still dealing with the rash on October 5th. I suspect it's mostly subsided because the itch is somewhat bearable now. The first thing I noticed was an odd skin reaction above the knee

Had major foot reconstruction (first sugery of my life) including a plate and donor bone and pins and they used chloraprep. They removed my surgical dressings after one week. The entire soul of my foot and all my toes were blistered into one massive

What dosage therapeutic category of this drug

Therapeutic Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Not yet recruiting Chlorhexidine Drying Time
Condition: Drying Time
Intervention: Drug: Chlorhexidine gluconate
Outcome Measure: Length of drying time
2 Recruiting Efficacy Study Comparing 2% Chlorhexidine in 70% Isopropyl Alcohol Versus 2% Aqueous Chlorhexidine
Condition: Anti-infecting Agents, Local
Interventions: Drug: 2% aqueous chlorhexidine;   Drug: 2% Chlorhexidine 70% isopropyl alcohol
Outcome Measures: Bacterial colony count as assessed by pre- and post cleansing skin swab culture.;   Immediate or late Skin reactions.
3 Not yet recruiting Waterless Hand Cleansing With Chlorhexidine During the Perinatal Period
Conditions: Hand Washing Behavior;   Hand Cleansing Behavior;   Chlorhexidine;   Neonatal Period
Interventions: Behavioral: Hand cleansing with chlorhexidine;   Behavioral: Mother and neonatal health counselling
Outcome Measures: Observed hand cleansing behavior of mother with chlorhexidine or soap and water at critical times;   Observed hand cleansing behavior of other household members and visitors to home with chlorhexidine or soap and water at critical times
4 Not yet recruiting The Efficacy and Safety of Chlorhexidine Gluconate Chip (PerioChip®) in Therapy of Peri-implantitis
Condition: Peri-Implantitis
Intervention: Drug: 2.5 mg Chlorhexidine gluconate chip
Outcome Measures: Absolute change in mean probing Pocket Depth for selected target implants;   Absolute change in mean probing Pocket Depth of selected target implants in patients with baseline Pocket Depth measurement of 6-8 mm inclusive;   Change in percentage of selected target implants Bleeding on Probing;   Absolute change in mean probing Pocket Depth of selected target implants
5 Not yet recruiting Chlorhexidine Versus Betadine in Preventing Colonization of Femoral Nerve Catheters After Total Joint Arthroplasty (TJA)
Condition: Infection
Interventions: Drug: Skin antisepsis with chlorhexidine;   Drug: povidone-iodine
Outcome Measures: Presence or absence of bacterial colonization of the distal femoral catheter tip 48 hours after antiseptic application;   Incidences of bacterial colonization of skin before/after skin antisepsis and skin/catheter interface
6 Not yet recruiting Effectiveness of Chlorhexidine Wipe for Prevention of Multidrug-resistant Organisms in Intensive Care Unit Patients
Condition: Antibiotic Resistant Infection
Intervention: Drug: 2% chlorhexidine wipe
Outcome Measures: The overall rate of Multidrug resistant bacteria acquisition at 7 days after received 2% chlorhexidine wipe bathing versus with soap bathing;   The overall rate of hospital-acquired bloodstream infections per 1000 patient-days with chlorhexidine wipe bathing versus with soap bathing
7 Unknown  Study of Chlorhexidine Gluconate as a Preoperative Antisepsis
Condition: Surgical Site Infection
Interventions: Drug: Povidone-Iodine;   Drug: Chlorhexidine gluconate
Outcome Measures: Number of patients with Surgical Site infection within 1month;   Identify the infection source;   Number of patients with Drug Side effect.;   Number of patients with the postoperative sepsis induced by wound infection
8 Recruiting Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application
Conditions: Lower Extremity Surgery;   Surgical Site Infection;   Bacterial Colonization;   Surgical Antiseptic
Intervention: Drug: Chloraprep
Outcome Measures: quantitative bacterial colonization;   positive culture rate;   bacterial strain identification
9 Not yet recruiting Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birth
Conditions: Neonatal Sepsis;   Neonatal Mortality Rate
Interventions: Drug: 0.25% chlorhexidine;   Drug: sterile water
Outcome Measures: Sepsis within first 7 days of life;   Readmissions & mortality rates within neonatal period;   Body temperature at 0, 5, 15, 30 minutes after application;   Skin condition;   Skin colonization rates;   Chlorhexidine percutaneous absorption
10 Recruiting Chlorhexidine Gluconate for Prevention of Ventilator Associated Pneumonia in Children.
Condition: Mechanical Ventilation for More Than 48 Hours.
Interventions: Drug: 0.12% chlorhexidine solution;   Drug: Placebo
Outcome Measures: Incidence of ventilator associated pneumonia;   Mortality;   Days of mechanical ventilation;   Length of stay
11 Not yet recruiting A Double-blind Evaluation of Adverse Effects of Bath With Wipes Impregnated With 2% Chlorhexidine Versus Placebo
Condition: Bed Bathing
Interventions: Procedure: Standardization phase;   Procedure: Control bath;   Procedure: Bath with chlorhexidine
Outcome Measures: Skin reaction to chlorhexidine;   Comparison of bacterial colony count of skin.
12 Unknown  Chlorhexidine Cordcare for Reduction in Neonatal Mortality and Omphalitis
Conditions: Neonatal Mortality;   Cord Care;   Omphalitis
Interventions: Drug: Chlorhexidine 4%;   Other: Control cord cleaning solution
Outcome Measures: Neonatal Mortality;   Omphalitis
13 Recruiting Effect of Chlorhexidine on Bacteriuria
Conditions: Urinary Tract Infection;   Nosocomial Infection;   Bacteriuria
Interventions: Drug: Povidone-iodine;   Drug: Chlorhexidine;   Drug: Normal saline
Outcome Measures: Bacteriuria day 1;   Bacteriuria day 3;   Bacteriuria day 5;   Bacteriuria day 7;   Bacteriuria day 9;   Microorganism Type day 5;   Microorganism type day 10
14 Recruiting Prehospital Ventilator-Associated Pneumonia Prevention Trial
Conditions: Wounds and Injuries;   Respiratory Failure;   Pneumonia, Ventilator-Associated
Intervention: Drug: Chlorhexidine gluconate
Outcome Measures: Clinical Pulmonary Infection Score (CPIS);   Pneumonia - CPIS;   Pneumonia - CDC;   Pneumonia - Treated;   Pneumonia - Research;   28-day ventilator-free days;   28-day ICU-free days;   Hospital Mortality;   Tracheostomy Rate;   Tracheal colonization
15 Not yet recruiting Prevention of Surgical Site Infection After Cesarean Delivery
Condition: Surgical Site Infection
Interventions: Drug: Chlorhexidine-alcohol group;   Drug: Povidone-Iodine Group
Outcome Measures: Incidence of Surgical Site Infection within 30 days of Cesarean Delivery;   Type of SSI (based on CDC classification);   Time to diagnosis of SSI
16 Recruiting Chlorhexidine as Coadjuvant in Dentin Adhesion of Noncarious Cervical Lesions
Condition: Non-carious Cervical Lesions
Interventions: Procedure: Treatment with chlorhexidine;   Procedure: Water pre-treatment
Outcome Measures: Change from baseline in Retention rates of the restoration at 24 months;   Change from baseline in Post-operative sensitivity at 6-month;   Change from baseline in marginal staining rates at 6. 12 and 24 months
17 Recruiting Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients
Conditions: Pathogenic Bacteria in the Oropharynx;   Ventilator-associated Pneumonia
Interventions: Procedure: Lactobacillus plantarum 299 for oral care;   Procedure: Chlorhexidine for standard oral care
Outcome Measures: To compare the number and frequency of cultures with pathogenic bacteria and fungi from the oropharynx and tracheal secretions and the spectra of these microbiological species;   Recovery of Lactobacillus plantarum 299 in tracheal secretions in the active treatment group as an indicator of aspiration;   SOFA score and Influence on lung function measured as Lung Injury Severity Score;   Difference in emerge of Ventilator Associated Pneumonia;   Validation of micobiological findings compared to the use of antibiotics;   C-reactive protein and white blood cell counts;   Evaluation of microbiological cultures taken on clinical grounds;   28 day mortality;   6 months mortality
18 Recruiting Open Prospective Study on Reduction of Bacteriuria Following Bladder Irrigation With Chlorhexidine
Condition: Bacteriuria, Intermittent Catheterization
Intervention: Device: Chlorhexidine
Outcome Measures: Proportion of patients with bacteriuria <10^3 CFU/ml;   Time (number of days) to reduction of bacteriuria (<10^3 CFU/ml)
19 Unknown  Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease
Condition: Coronary Artery Disease
Interventions: Device: Firebird 2 sirolimus-eluting stent;   Device: Excel sirolimus-eluting stent
Outcome Measures: in-stent late lumen loss at 9 months' angiographic follow-up;   target vessel failure
20 Unknown  Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn Infants
Condition: Catheterization
Intervention: Device: 3.15% chlorhexidine as daily antiseptic on needleless access port
Outcome Measures: Catheter tip microbial colonization;   Time to hub microbial colonization;   Route of catheter tip microbial colonization determined by cultures taken at the catheter hub versus skin