Ulcer and Omeprazole


Ulcer Symptoms and Causes

A peptic Ulcer is a sore in the lining of your stomach or your duodenum, the first part of your small intestine. A burning stomach pain is the most common symptom. The pain

  • Starts between meals or during the night
  • Briefly stops if you eat or take antacids
  • Lasts for minutes to hours
  • Comes and goes for several days or weeks

Peptic Ulcers happen when the acids that help you digest food damage the walls of the stomach or duodenum. The most common cause is infection with a bacterium called Helicobacter pylori. Another cause is the long-term use of nonsteroidal anti-inflammatory medicines (NSAIDs) such as aspirin and ibuprofen. Stress and spicy foods do not cause Ulcers, but can make them worse.

To see if you have an H. pylori infection, your doctor will test your blood, breath, or stool. Your doctor also may look inside your stomach and duodenum by doing an endoscopy or x-ray.

Peptic Ulcers will get worse if not treated. Treatment may include medicines to reduce stomach acids or antibiotics to kill H. pylori. Antacids and milk can't heal peptic Ulcers. Not smoking and avoiding alcohol can help. You may need surgery if your Ulcers don't heal.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

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Omeprazole Side Effects

Hypomagnesaemia (419)
Diarrhoea (311)
Hypocalcaemia (288)
Nausea (285)
Renal Failure Acute (241)
Vomiting (240)
Dyspnoea (225)
Dizziness (205)
Gastrooesophageal Reflux Disease (191)
Fatigue (169)
Pain (164)
Abdominal Pain (163)
Headache (157)
Malaise (155)
Dyspepsia (152)
Rash (148)
Asthenia (146)
Fall (137)
Abdominal Pain Upper (133)
Confusional State (130)
Hypokalaemia (126)
Condition Aggravated (125)
Pruritus (120)
Arthralgia (118)
Anxiety (117)
Tubulointerstitial Nephritis (116)
Pyrexia (116)
Hyponatraemia (115)
Product Substitution Issue (113)
Paraesthesia (112)
Weight Decreased (111)
Muscle Spasms (109)
Anaemia (106)
Decreased Appetite (104)
Chest Pain (100)
Dysphagia (93)
Convulsion (88)
Dehydration (86)
Depression (84)
Cough (84)
Lethargy (79)
Urticaria (78)
Constipation (78)
Muscular Weakness (78)
Pain In Extremity (76)
Myalgia (76)
Tetany (73)
Tremor (73)
Oedema Peripheral (73)
Pneumonia (72)

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Common Meds

Abilify (10132)
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Amoxicillin (4387)
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Recent Reviews

I started taken omeprazole. I ran out of my Nexum well I started itching really bad as it I had bug bites believe me I will never uses this again. I've never had reaction to a med before

I stopped taking Omeprazole 20mg after 4 days because of a side effect, strong palpitations most of the time; I stopped taking them a week ago and still have the palpitations. It's very scary........

I am experiencing itching on my arms, rashes on arms and shoulders, hoarseness, slight dizziness, trouble sleeping and mild headaches. I was prescribed this medication for treatment of bloating caused by my hiatal hernia but can

After 2 weeks skin burning on chest and back nevrous sytoms O:-) :'(

After the 1st week I suffered from severe dizzyness, nausea and headaches. Vomited everything I ate. Yet around 5pm I would always feel relatively human again.

An update, It has only been 3 days & my arm pain has gone!!, for anybody suffering similar symptoms to mine this is what i done...1.STOP taking omeprazole. 2. buy plenty bottled water & drink upto 6 bottles per day. 3 eat healthy (det

Been taking omeprazole for 6 years. during that time diagnosed with osteoporsis. after reading about this seems any proton pump inhibitor can cause. so angry with doctor. looking now for new drug, severe gerd and hiatal hernia.

Both arms , upper arm muscle weakness and pain, , dosage 40mg twice a day

By day 4 severe leg pain, joing pain and cramping and prior never had this pain. All my muscles appear to be tighting up and going to discontinue this ASAP. I guess I am having a very rare reation to Prilosec.

Coral, So sorry to hear about your UC. I'm 47 and have had it for 17 years but mostly in remission. Ask your Dr. about Librax, It really helps with the pain of UC when going to bathroom. Good luck and God Bless!

After taking clonidine 0.1mg cut 9in half, for two dauys, twicw a day: it felt like a I had a terrible gastric ulcer. i TOOK IYT WITH A MEAL AND DRANK 10 OUNCES OF WATER. i took it again the next day with the same result. Do they

Had cosmetic dentistry and my doctor gave me apranax after one week i got bad pains in stomach after two weeks it went to my upper chest and back i now have a stomach ulcer be very careful as this drug is used by dentists to treat

Hi, i had menstrual pain yesterday and had 2 of the tablets. felt instant relief.I have been having severe chest pain all day. i have been treated for peptic ulcer there any possibility this drug has anything to do wth the pain?

Hi, i sufer from gastric ulcer and im treated with colofac and pantoprazole and after abaute 3days of using these drugs i experienced the diarrhoea and i had it for 2 weeks. so i left using colofac and every thing was going good for 2days, but after

I also experienced similar effects. I am taking 500mg clorom for a stomach ulcer as well as another antibiotic amoxcillin and an acid inhibitor lansoprazole. I am on day 5 of 7. After a day and a half of taking 2 clorom a day I started to get a bad h

I am taking 500mg clorom for a stomach ulcer as well as another antibiotic amoxcillin and an acid inhibitor lansoprazole. I am on day 5 of 7. After a day and a half of taking 2 a clorom a day I started to get a bad headache on the side of my head for

I am taking pan 40 mg daily as a rutine base in morning empty stomuch due to ulcer & reflex problem as per directed by my Dr. from last 2- 3 years regularly. before i take rabimac 20 mg daily from last 5-6 years regularly. i have migrane & st

I had a friend shes 20 yrs.old..had peptic ulcer.just wanna know if theres away to relief the pain.?

I had breathing difficulty so doctor prescribed me tab cetirizine. As i am having ulcer also. S o i wanna know that is this tab good affects for ulcers more.

I have all the side effect symptons but i never realised that it is a side effect thinking that am having acid reflux and taking ulcer treatment untill seven years later when i have had enough treatment with out cure then i think and remember that i

Ulcer Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Unknown  Comparison of Ulcer Healing in Patients Taking Rabeprazole With Different Antiplatelets
Conditions: Gastric Ulcer;   Duodenal Ulcer
Intervention: Drug: rabeprazole plus aspirin versus rabeprazole plus clopidogrel
Outcome Measures: The primary end point is treatment success (Ulcer healing rate).;   The secondary end point is incidence of Ulcer bleeding within 12 weeks.
2 Unknown  Study of the Efficacy of PedyPhar® Ointment on the Diabetic Foot Ulcers
Condition: Diabetic Foot Ulcer
Interventions: Drug: Royal Jelly and Panthenol (PedyPhar® Ointment);   Drug: Panthenol Ointment
Outcome Measures: Healing of the Ulcer;   reduction of infection in the Ulcer site;   local reaction that may be due to study drug
3 Unknown  Peptic Ulcer Disease in Ischemic Heart Patients Taking Aspirin and Clopidogrel With or Without Proton Pump Inhibitor
Conditions: Peptic Ulcer;   Ulcer Complications
Interventions: Drug: lansoprazole;   Drug: aluminum hydroxide 334 mg and Mg hydroxide 166 mg
Outcome Measures: The primary end point is the occurrence of clinical upper GI events (symptomatic Ulcer and Ulcer complications-bleeding, perforation, or obstruction);   The secondary end point is occurrence of dyspepsia, asymptomatic gastroduodenal Ulcers
4 Recruiting Evaluation of CureXcell® in Treating Chronic Venous Leg Ulcers
Condition: Chronic Venous Leg Ulcers
Interventions: Biological: CureXcell®;   Other: Placebo injection
Outcome Measures: Time to complete closure of Target Ulcer;   Proportion of complete closure of Target Ulcer;   Percentage change from baseline in Target Ulcer surface area;   Proportion of Target Ulcer recurrence
5 Recruiting Predictive of Biomarkers of Healing in Chronic Venous Ulceration of the Lower Limb
Condition: Varicose Ulcer
Outcome Measures: Biological profile of healing venous Ulcers versus non-healing venous Ulcers;   Differential biological response in non healing Ulcers treated with a biological dressing.
6 Recruiting Systematic Screening for Risk-factors for Ulcer Bleeding Before Anti-thrombotic Treatment
Conditions: Coronary Occlusion/Thrombosis;   Peptic Ulcer Hemorrhage
Intervention: Other: Screening for risk factors for Ulcer bleeding
Outcome Measures: Admission for Ulcer bleeding or haemorrhagic gastritis;   Compliance with antithrombotic medicine;   Identification of patients with Benefit of Proton pump inhibitor Prophylaxis;   Gastrointestinal bleeding;   Uncomplicated Ulcers;   Death;   Acute coronary syndrome
7 Recruiting Pressure Ulcer Healing With Microcyn
Conditions: Pressure Ulcer;   Spinal Cord Injuries
Interventions: Drug: Microcyn;   Other: Sterile saline
Outcome Measures: pressure Ulcer size (length, width, depth);   pressure Ulcer size (length, width and depth) at 4 weeks after baseline;   pressure Ulcer size (length, width and depth) at 8 weeks after baseline;   pressure Ulcer size (length, width and depth) at 12 weeks after baseline;   pressure Ulcer size (length, width and depth) at 16 weeks after baseline;   pressure Ulcer size (length, width and depth) at 20 weeks after baseline;   pressure Ulcer size (length, width and depth) at 24 weeks after baseline;   Pressure Ulcer Scale for Healing (PUSH) score;   Pressure Ulcer scale for Healing (PUSH) score at 4 weeks after baseline;   Pressure Ulcer scale for Healing (PUSH) score at 8 weeks after baseline;   Pressure Ulcer scale for Healing (PUSH) score at 12 weeks after baseline;   Pressure Ulcer scale for Healing (PUSH) score at 16 weeks after baseline;   Pressure Ulcer scale for Healing (PUSH) score at 20 weeks after baseline;   Pressure Ulcer scale for Healing (PUSH) score at 24 weeks after baseline
8 Recruiting Telemedicine Follow-up in Primary Health Care for Diabetes-related Foot Ulcers
Conditions: Diabetic Foot;   Foot Ulcer
Intervention: Procedure: Telemedicine follow-up care
Outcome Measures: healing time for diabetes related foot Ulcer;   Total number of consultations per person at the Section of Endocrinology;   sequela directly related to the foot Ulcer;   Diabetes-related stress;   Symptoms of anxiety and depression;   Nordic Patient Experiences Questionnaire;   EQ-5D;   Sick leave;   A new foot Ulcer appears, the incidence of amputation and survival.
9 Recruiting Ulcer Monitoring in Diabetes Mellitus
Conditions: Diabetes Mellitus;   Foot Ulcers
Intervention: Procedure: telemedicine consultations
Outcome Measures: Admissions to hospital;   Surgical procedures;   Ulcer healing
10 Recruiting Timing of Surgical Intervention in Buruli Ulcer Patients Treated With Antibiotics
Conditions: Mycobacterium Ulcerans Disease;   Buruli Ulcer
Intervention: Procedure: surgical intervention on Buruli Ulcer
Outcome Measure: Healing without surgical intervention
11 Unknown  Pathophysiology of Martorell Hypertensive Ischemic Leg Ulcer (HYTILU)
Conditions: Hypertensive Ischemic Leg Ulcer;   Calciphylaxis
Outcome Measures: Martorell HYTILU and calciphylaxis show both decreased tissue protection mechanisms against tissue calcification;   Martorell hypertensive ischemic leg Ulcer and calciphylaxis are both characterized by non-infectious inflammation
12 Unknown  Monochromatic Phototherapy on Diabetic Foot Ulcers
Condition: Diabetic Foot Ulcers
Interventions: Device: Monochromatic phototherapy, Biolight®;   Device: Monochromatic phototherapy
Outcome Measures: Number of subjects who completely healed and time to 100% wound reduction.;   Time to 50% wound reduction, Subjects with increased Ulcer and/or wound reduction less than 20%, Wound status, Elimination of gram-positive and anaerobic bacteria from the wound, Hospitalization caused of foot Ulcer, Presence and level of amputation
13 Recruiting The Therapeutical Role of Continuous Intra-femoral Artery Infusion of Urokinase on Diabetic Foot Ulcers
Condition: Diabetic Foot Ulcer
Interventions: Drug: continuous intra-femoral thrombolysis group;   Drug: Conventional therapy group
Outcome Measures: healing rate of diabetic foot Ulcers;   The recurrence rate of diabetic foot Ulcers;   cardiovascular events during the follow up period
14 Recruiting Evaluation of CureXcell® in Treating Lower Extremity Chronic Ulcers in Adults With Diabetes
Condition: Lower Extremity Chronic Ulcers in Diabetics
Interventions: Biological: CureXcell®;   Biological: Sham injection
Outcome Measures: Proportion of patients with complete healing/closure of their target Ulcer at any time during the 16-week double-blind core treatment period with sustained complete closure for 4 additional weeks of follow-up.;   Time to complete closure of the Target Ulcer during the core double blind treatment phase with sustained complete closure for 4 additional weeks of follow-up.;   Proportion of patients with at least 50% closure of target Ulcer during the 16-week core treatment period.;   Proportion of patients whose Target Ulcer completely closed during the core double blind treatment phase and remained closed at the FU12 follow-up visit.
15 Recruiting Feasibility and Safety and Evaluation of the Potential Efficacy of Autologous Platelet-rich Plasma in the Treatment of Vascular Venous Ulcers
Condition: Chronic Vascular Ulcer
Interventions: Biological: Platelet Rich Plasma;   Device: "Antimicrobial debridin", "hydrocolloids", "alginates and hydrofibres", "polyurethane foams", "barrier products"
Outcome Measures: Change of Ulcer AREA;   Change of the percentage OF PATIENTS WITH A ONLY ONE TREATMENT FOR WEEK;   REDUCTION IN Ulcer SIZE;   Change of the CIVIQ SCORE
16 Recruiting H2RA VS PPI for the Prevention of Ulcer Bleeding Associated With Low-dose Aspirin in Patients With Very High Ulcer Risk
Condition: Peptic Ulcer Bleeding
Interventions: Drug: Rabeprazole;   Drug: Famotidine
Outcome Measures: Recurrent Ulcer bleeding;   Lower GI bleeding;   serious cardiothrombotic events
17 Unknown  Is Rebamipide Effective on the Healing of Iatrogenic Gastric Ulcer After Endoscopic Mucosal Resection?
Condition: Stomach Ulcer
Interventions: Drug: Rebamipide;   Drug: pantoprazole
Outcome Measure: Healing efficacy of Rebamipide in the treatment of iatrogenic gastric Ulcer
18 Recruiting Risk Factors of Rebleeding After Peptic Ulcer Bleeding: a Nationwide Cohort Study
Condition: Peptic Ulcer Bleeding
Outcome Measures: Rebleeding rate of peptic Ulcer bleeding;   Mortality rates of peptic Ulcer bleeding
19 Recruiting PPI vs H2RA in Patients With Helicobacter Pylori-Negative Idiopathic Bleeding Ulcers
Condition: Peptic Ulcer
Interventions: Drug: Lansoprazole;   Drug: Famotidine
Outcome Measures: Recurrent Ulcer bleeding;   Recurrent Ulcer detected by endoscopy at 24-month
20 Recruiting Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers
Condition: Diabetic Foot Ulcers
Interventions: Drug: DSC127;   Drug: placebo vehicle gel
Outcome Measures: The proportion of subjects with a target Ulcer which achieves complete wound closure (skin re-epithelialization without drainage or dressing requirements) up to 10 weeks (confirmed at a study visit 2 weeks later).;   Time to the visit where the target Ulcer achieves confirmed complete wound closure occurs