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Lyrica Depression Side Effects

Lyrica Depression Side Effect Reports


The following Lyrica Depression side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Depression, can occur, and what you can do about them.

A side effect could appear soon after you start Lyrica or it might take time to develop.



Angina Pectoris, Osteoarthritis, Intervertebral Disc Disorder, Arthralgia, Anxiety, Hyperlipidaemia, Hypothyroidism, Depression, Gastrooesophageal Reflux Disease

This Depression side effect was reported by a physician from US. A 66-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Lyrica (dosage: 150 Mg, 3x/day), which was started on Dec 31, 2013. Concurrently used drugs:
  • Prempro (0.625mg/ 2.5mg, Qd)
  • Aspirin (81 Mg, Every Day)
  • Nexium (40 Mg, 1x/day)
  • Oxygen (2 Lpm Nocturnal)
  • Nitroglycerin (0.4 Mg, Prn Use)
  • Pravastatin (20 Mg, Every Day)
  • Vagifem (10 Ug, 2 Times Every Week)
  • Norco (10 Mg-325 Mg, Every 6 Hours As Needed)
When starting to take Lyrica the consumer reported the following symptoms:
  • Angina Pectoris
  • Osteoarthritis
  • Intervertebral Disc Disorder
  • Arthralgia
  • Anxiety
  • Hyperlipidaemia
  • Hypothyroidism
  • Depression
  • Gastrooesophageal Reflux Disease
These side effects may potentially be related to Lyrica.
Suicidal Ideation, Hepatic Failure, Renal Failure, Depression

This Depression Lyrica side effect was reported by a consumer or non-health professional from US on Mar 06, 2014. A Female , 49 years of age, weighting 138.0 lb, was diagnosed with and was treated with Lyrica. The patient presented the following health conditions:
  • Suicidal Ideation
  • Hepatic Failure
  • Renal Failure
  • Depression
. Lyrica dosage: Unk, 2x/day. Additional drugs used at the same time: NA. The patient was hospitalized.
Depression, Suicidal Ideation, Gait Disturbance, Faecal Incontinence, Urinary Incontinence, Renal Haemorrhage

This is a Lyrica 75 Mg Pfizer side effect report of a 57-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Lyrica 75 Mg Pfizer (dosage:NA, start time: NS), combined with: NA., and developed a serious reaction and a Depression side effect. The patient presented with:
  • Depression
  • Suicidal Ideation
  • Gait Disturbance
  • Faecal Incontinence
  • Urinary Incontinence
  • Renal Haemorrhage
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Lyrica 75 Mg Pfizer treatment in female patients suffering from NA, resulting in Depression.

Upper Respiratory Tract Infection, Tooth Infection, Headache, Back Pain, Musculoskeletal Pain, Insomnia, Depression, Tympanic Membrane Disorder

A 46-year-old female patient (weight: NA) from US with the following symptoms: fibromyalgia,pain started Lyrica treatment (dosage: 150 Mg, 4x/day) on NS. Soon after starting Lyrica treatment, the consumer experienced several side effects, including:
  • Upper Respiratory Tract Infection
  • Tooth Infection
  • Headache
  • Back Pain
  • Musculoskeletal Pain
  • Insomnia
  • Depression
  • Tympanic Membrane Disorder
. Concurrently used drugs:
  • Tramadol Hydrochloride (50 Mg, 1-2 Tablet As Needed Every 8 Hours)
  • Diflucan (150 Mg, 1x/day)
  • Hydrocodone W/acetaminophen (5-325 Mg, Twice A Day (020) As Needed (010))
  • Benazepril Hydrochloride (20 Mg, 1x/day)
  • Diltiazem Hydrochloride (90 Mg, 2x/day Before Meal And At Bedtime)
  • Prevacid (90 Mg, 2x/day)
This finding indicates that some patients can be more vulnerable to developing Lyrica side effects, such as Depression.
Off Label Use, Cerebrovascular Accident, Depression, Dizziness

A patient from CO was prescribed and started Lyrica on Feb 12, 2014. Patient felt the following Lyrica side effects: off label use, cerebrovascular accident, depression, dizziness Additional patient health information: male , 84 years of age, The consumer reported the following symptoms: was diagnosed with and. Lyrica dosage: 75 Mg, 1x/day. Concurrently used drugs: NA.
Off Label Use, Pelvic Pain, Visual Impairment, Visual Acuity Reduced, Sedation, Feeling Drunk, Depression, Fatigue

This report suggests a potential Lyrica Depression side effect(s) that can have serious consequences. A 41-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): pelvic pain,neuralgia,complex regional pain syndrome and used Lyrica (dosage: 25 Mg, Unk) starting Nov 28, 2013. Soon after starting Lyrica the patient began experiencing various side effects, including:
  • Off Label Use
  • Pelvic Pain
  • Visual Impairment
  • Visual Acuity Reduced
  • Sedation
  • Feeling Drunk
  • Depression
  • Fatigue
Drugs used concurrently:NA. Although Lyrica demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Depression, may still occur.
Off Label Use, Neuralgia, Depression, Impaired Driving Ability, Chest Pain

An adverse event was reported by a consumer or non-health professional on Feb 04, 2014 by a male taking Lyrica (dosage: 450 Mg, 1x/day) was diagnosed with and. Location: US , 47 years of age, weighting 150.0 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Lyrica side effects: off label use, neuralgia, depression, impaired driving ability, chest pain. Additional medications/treatments:
Depression, Weight Decreased

This Depression problem was reported by a consumer or non-health professional from US. A 53-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): convulsion,epilepsy,pain.On 201011 a consumer started treatment with Lyrica (dosage: 75 Mg, 2x/day). The following drugs/medications were being taken at the same time: NA. When commencing Lyrica, the patient experienced the following unwanted symptoms /side effects:
  • Depression
  • Weight Decreased
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Depression, may become evident only after a product is in use by the general population.
Convulsion, Hallucination, Depression

This is a Lyrica side effect report of a 72-year-old female patient (weight: NA) from EC. The patient developed the following symptoms/conditions: neuralgia,diabetes mellitus and was treated with Lyrica (dosage: 75 Mg, 2x/day) starting 2012. Concurrently used drugs:
  • Insulin
Soon after that, the consumer experienced the following of symptoms:
  • Convulsion
  • Hallucination
  • Depression
This opens a possibility that Lyrica could cause Depression and that some female patients may be more susceptible.
Depression, Mobility Decreased

This Depression side effect was reported by a consumer or non-health professional from US on Jan 17, 2014. A female patient from US , 47 years of age, weighting 138.0 lb, was diagnosed with and was treated with Lyrica. Directly after treatment started, patient experienced the unwanted or unexpected Lyrica side effects: depression, mobility decreased. Lyrica dosage: 50 Mg, Unk. These side effects may potentially be related to Lyrica.
Loss Of Consciousness, Oxygen Saturation Decreased, Depression, Mood Altered, Eye Swelling, Ocular Hyperaemia, Feeling Abnormal, Weight Increased, Fatigue

This Depression side effect was reported by a consumer or non-health professional from US. A 40-year-old patient (weight:NA) experienced the following symptoms/conditions: nervous system disorder,craniocerebral injury. The patient was prescribed Lyrica (dosage: Unk (900 Mg In A Day)), which was started on 2013. Concurrently used drugs: NA. When starting to take Lyrica the consumer reported the following symptoms:
  • Loss Of Consciousness
  • Oxygen Saturation Decreased
  • Depression
  • Mood Altered
  • Eye Swelling
  • Ocular Hyperaemia
  • Feeling Abnormal
  • Weight Increased
  • Fatigue
These side effects may potentially be related to Lyrica.
Depression, Pain, Malaise

This Depression Lyrica side effect was reported by a consumer or non-health professional from US on Jan 13, 2014. A Female , 52 years of age, weighting 200.0 lb, was treated with Lyrica. The patient presented the following health conditions:
  • Depression
  • Pain
  • Malaise
. Lyrica dosage: 100 Mg, 4x/day. Additional drugs used at the same time: NA.
Suicidal Ideation, Hallucination, Depression

This is a Lyrica side effect report of a 59-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: pain, who was treated with Lyrica (dosage:Unk, start time: NS), combined with:
  • Neurontin (Unk)
  • Mirapex (Unk)
  • Amlodipine (Unk)
  • Cymbalta (90 Mg, Qday)
  • Diazepam (5 Mg, Qday)
  • Fluoxetin (40 Mg, Qday)
  • Lidoderm (Unk)
  • Naproxen (Unk)
, and developed a serious reaction and a Depression side effect. The patient presented with:
  • Suicidal Ideation
  • Hallucination
  • Depression
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Lyrica treatment in female patients suffering from pain, resulting in Depression.
Depression, Disturbance In Attention

A 46-year-old female patient (weight: NA) from US with the following symptoms: NA started Lyrica treatment (dosage: 50 Mg, 3x/day) on NS. Soon after starting Lyrica treatment, the consumer experienced several side effects, including:
  • Depression
  • Disturbance In Attention
. Concurrently used drugs:
  • Celebrex (200 Mg, 2x/day)
  • Lexapro (20 Mg, 1x/day)
  • Naproxen (500 Mg, 2x/day)
This finding indicates that some patients can be more vulnerable to developing Lyrica side effects, such as Depression.
Neoplasm Malignant, Anxiety, Depression, Anaemia, Tremor, Nausea

A female patient from US was prescribed and started Lyrica on Dec 26, 2013. After Lyrica was administered, patient encountered several Lyrica side effects: neoplasm malignant, anxiety, depression, anaemia, tremor, nausea Additional patient health information: Female , 59 years of age, weighting 160.0 lb, The consumer reported the following symptoms: was diagnosed with and. Lyrica dosage: 150 Mg, 3x/day. Concurrently used drugs:
  • Dilaudid (Unk)
  • Effexor-xr (Unk)
  • Trazodone (Unk)
  • Protonix (Unk)
Vertigo, Abnormal Behaviour, Suicide Attempt, Anger, Depression, Disturbance In Attention, Migraine

This report suggests a potential Lyrica Depression side effect(s) that can have serious consequences. A 49-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): pain and used Lyrica (dosage: NA) starting NS. Soon after starting Lyrica the patient began experiencing various side effects, including:
  • Vertigo
  • Abnormal Behaviour
  • Suicide Attempt
  • Anger
  • Depression
  • Disturbance In Attention
  • Migraine
Drugs used concurrently:
  • Combivent
  • Serevent
  • Prilosect
  • Thyroid Rx
  • Xopenex
  • Loratab
  • Sumavel Dose Pro
  • Ibprofen
Although Lyrica demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Depression, may still occur.
Suicidal Ideation, Depression, Weight Decreased, Vision Blurred, Weight Increased, Thinking Abnormal, Pain, Psychomotor Hyperactivity, Somnolence

An adverse event was reported by a consumer or non-health professional on Jan 27, 2014 by a Female taking Lyrica (dosage: 200 Mg, 3x/day) was diagnosed with and. Location: US , 55 years of age, weighting 184.0 lb, patient began experiencing various side effects, including: Patient felt the following Lyrica side effects: suicidal ideation, depression, weight decreased, vision blurred, weight increased, thinking abnormal, pain, psychomotor hyperactivity, somnolence. Additional medications/treatments:
Depression, Therapeutic Response Unexpected

This Depression problem was reported by a consumer or non-health professional from US. A 34-year-old patient (weight: NA) was diagnosed with the following medical condition(s): neuralgia,back pain.On NS a consumer started treatment with Lyrica (dosage: 300 Mg, 2x/day). The following drugs/medications were being taken at the same time: NA. When commencing Lyrica, the patient experienced the following unwanted symptoms /side effects:
  • Depression
  • Therapeutic Response Unexpected
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Depression, may become evident only after a product is in use by the general population.
Gait Disturbance, Mobility Decreased, Depression, Frustration, Pain, Pain In Extremity

This is a Lyrica side effect report of a 51-year-old patient (weight: NA) from US. The patient developed the following symptoms/conditions: neuralgia,back pain,diabetes mellitus and was treated with Lyrica (dosage: Unk (75mg Capsule In Morning, 75mg Capsule In Afternoon And 150mg At Night), 3x/day) starting Jun 10, 2010. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Gait Disturbance
  • Mobility Decreased
  • Depression
  • Frustration
  • Pain
  • Pain In Extremity
This opens a possibility that Lyrica could cause Depression and that some patients may be more susceptible.
Vision Blurred, Dizziness, Dry Mouth, Weight Increased, Depression, Insomnia, Fatigue, Stress, Anger

This Depression side effect was reported by a consumer or non-health professional from US on Jan 15, 2014. A female patient from US , 49 years of age, weighting 217.0 lb, was diagnosed with and was treated with Lyrica. Patient felt the following Lyrica side effects: vision blurred, dizziness, dry mouth, weight increased, depression, insomnia, fatigue, stress, anger. Lyrica dosage: Unk. These side effects may potentially be related to Lyrica.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Lyrica Depression Causes and Reviews


Depression is a serious medical illness. It's more than just a feeling of being sad or "blue" for a few days. If you are one of the more than 19 million teens and adults in the United States who have Depression, the feelings do not go away. They persist and interfere with your everyday life. Symptoms can include

  • Feeling sad or "empty"
  • Loss of interest in favorite activities
  • Overeating, or not wanting to eat at all
  • Not being able to sleep, or sleeping too much
  • Feeling very tired
  • Feeling hopeless, irritable, anxious, or guilty
  • Aches or pains, headaches, cramps, or digestive problems
  • Thoughts of death or suicide

Depression is a disorder of the brain. There are a variety of causes, including genetic, biological, environmental, and psychological factors. Depression can happen at any age, but it often begins in teens and young adults. It is much more common in women. Women can also get postpartum Depression after the birth of a baby. Some people get seasonal affective disorder in the winter. Depression is one part of bipolar disorder.

There are effective treatments for Depression, including antidepressants, talk therapy, or both.

NIH: National Institute of Mental Health


Lyrica Depression Reviews

Wed, 20 Aug 2008
I am a retired pharmacist and I also take Lyrica. I have only experienced weight gain as a side effect. In my own case, I have had moderate to severe Depression/mood disorder for several years and Lyrica has made me a new woman. I feel completely normalized. I have been on it for 2 months. I suggest(as long as you and your doctor have ruled out allergy, which I doubt) that you give it a little time.
Fri, 19 Nov 2010
I've been taking Lyrica for several years for diabetic neuropathy and have been so grateful for at least occassional relief from the pain that I have just had to "live with" the side effects: Depression/suicidal thoughts weight gain dizziness - loss of balance sleepiness memory loss The last two side effects are taking a toll on me in terms of threatening my job! I fall asleep at my desk, and it's a real problem! Also I find that some days it doesn't seem to be working at all.... the pain is unrelenting and just as if I had missed a dose. Anyone else have that problem? Is there anyone to go to for answers? Thank you.
Sun, 06 Feb 2011
My wife was taking Lyrica along with Zoloft and Tramidol last July for her Fibromyalgia and a pain syndrome. It made her feel miserable. She could not describe everything that was going through her brain, but I saw that she was confused, irritable, had new leg pain and a rash developed. When she called the doctor about the rash he finally told her to stop taking it. This did not give her immediate relief. Some of the symptoms continued, especially the far out-of-character mood swings. During one mood swing she tripped and fell and became someone I had never seen before. She acted like a child, screamed at the top of her lungs and accused me of "Chest Bumping" her, even though this was impossible. Needless to say I went to jail that night for "Assault" and it took several weeks before the drugs were out of her system enough that she realized what happened. Her Depression over the whole incident led her to believe I had left her because of her behavior, although I was not allowed to have any contact with her. Because we had no contact and she was not included in court proceedings, eventually I felt the best thing to do was plead "No Contest" where I was given credit for the time I served and probation. Eventually she attempted to contact me and learned what had happened and immediately had the court remove the no contact order. To this day we are still not allowed to live together or have much more than telephone contact. No matter what she says now, she is always treated like my "victim" and as if she is too stupid to leave an abuser. Unfortunately she has suffered worse than myself because I have always been her care giver and she has been forced to care for herself when she is frequently in too much pain and too exhausted to get out of bed. I hope there is a special hell for those who push this irresponsible drug on victims like my wife.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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