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Alfarol Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 44 

Rash (8443188-8)
on Jun 05, 2012 Male from JAPAN , 68 years of age, was treated with Alfarol. Directly after, patient experienced the unwanted or unexpected Alfarol side effects: rash. Alfarol dosage: N/A.
Associated medications used:
  • Nateglinide
  • Rebetol
  • Peginterferon Alfa-2b
  • Locholest
  • Telavic (telaprevir)


Liver Disorder, Haemosiderosis, Hepatitis, Fatigue, Periportal Oedema (8406261-6)
Patient was taking Alfarol. Patient felt the following Alfarol side effects: liver disorder, haemosiderosis, hepatitis, fatigue, periportal oedema on May 28, 2012 from JAPAN Additional patient health information: Female , weighting 79.37 lb, . Alfarol dosage: 0.5 Ug, Unk.
Multiple prescriptions taken:
  • Exjade (1000 Mg, Daily)
  • Fosamax (5 Mg, Unk)
  • Pravastatin Sodium (10 Mg, Unk)
  • Exjade (1000 Mg, Daily)
  • Calblock (16 Mg, Unk)
  • Glakay (45 Mg, Unk)
  • Exjade (500 Mg, Daily)


Myocardial Ischaemia (8402153-7)
Adverse event was reported on May 18, 2012 by a Female taking Alfarol (Dosage: 1 Df, Daily) was diagnosed with
  • osteoporosis
  • peripheral circulatory failure
and. Location: JAPAN , weighting 92.59 lb, After Alfarol was administered, patient encountered several Alfarol side effects: myocardial ischaemia.
Multiple concurrent drugs taken:
  • Tocopherol /00110502/ (600 Mg, Daily)
  • Buprenorphine
  • Olmesartan Medoxomil (1 Df, Daily)
  • Buprenorphine (5 Mcg, Q1h)
  • Mobic (1 Df, Daily)
  • Lansoprazole (1 Df, Daily)
  • Alendronate Sodium (1 Df, Daily)
  • Buprenorphine


Loss Of Consciousness, Road Traffic Accident, Dermatitis (8347374-7)
on May 01, 2012 Male from JAPAN , weighting 116.8 lb, was diagnosed with
  • renal failure chronic
and was treated with Alfarol. Directly after, patient experienced the unwanted or unexpected Alfarol side effects: loss of consciousness, road traffic accident, dermatitis. Alfarol dosage: N/A.
Associated medications used:
  • Argamate
  • Mircera
Patient was hospitalized.


Haemoglobin Decreased, Gastrointestinal Erosion (8338403-5)
on Apr 26, 2012 Male from JAPAN , weighting 112.4 lb, was treated with Alfarol. Patient felt the following Alfarol side effects: haemoglobin decreased, gastrointestinal erosion. Alfarol dosage: N/A.
Multiple prescriptions taken:
  • Tenormin
  • Omeprazole
  • Epogin S
  • Plavix
  • Atelec
  • Mircera
  • Epogin S
  • Besacolin
Patient was hospitalized.

Macular Oedema (8295906-X)
Patient was taking Alfarol. After Alfarol was administered, patient encountered several Alfarol side effects: macular oedema on Apr 02, 2012 from JAPAN Additional patient health information: Female , weighting 94.80 lb, was diagnosed with
  • osteoporosis
  • hypercholesterolaemia
  • constipation prophylaxis
  • peripheral sensory neuropathy
and. Alfarol dosage: N/A.
Multiple concurrent drugs taken:
  • Lipitor
  • Milmag
  • Lyrica
  • Milmag
  • Abraxane
  • Actonel
  • Zometa
  • Abraxane (132 Milligram)


Loss Of Consciousness, Road Traffic Accident, Dermatitis (8282933-1)
Adverse event was reported on Mar 30, 2012 by a Male taking Alfarol (Dosage: N/A) was diagnosed with
  • renal failure chronic
and. Location: JAPAN , weighting 116.8 lb, Directly after, patient experienced the unwanted or unexpected Alfarol side effects: loss of consciousness, road traffic accident, dermatitis.
Associated medications used:
  • Argamate
  • Mircera
Patient was hospitalized.

Blood Parathyroid Hormone Increased, Hypocalcaemia, Hyperphosphataemia (8216573-7)
on Mar 07, 2012 Male from JAPAN , child 2 years of age, weighting 17.64 lb, was treated with Alfarol. Patient felt the following Alfarol side effects: blood parathyroid hormone increased, hypocalcaemia, hyperphosphataemia. Alfarol dosage: 0.5 Mug, Qd.
Multiple prescriptions taken:
  • Oxarol (2.5 Mug, 3 Times/wk -15 Time Execution)
  • Renagel (250 Mg, Qd)
  • Renagel (250 Mg, Tid)
  • Calcium Carbonate (1 G, Tid)
  • Cinacalcet Hydrochloride
  • Cinacalcet Hydrochloride
  • Ferrous Citrate
Patient was hospitalized.

Retinal Haemorrhage (8209552-7)
on Mar 06, 2012 Female from JAPAN , 60 years of age, was treated with Alfarol. After Alfarol was administered, patient encountered several Alfarol side effects: retinal haemorrhage. Alfarol dosage: N/A.
Multiple concurrent drugs taken:
  • Folic Acid
  • Loxonin
  • Prednisolone
  • Simponi
  • Famotidine
  • Rheumatrex


Blood Sodium Increased, Blood Potassium Increased, Blood Creatinine Increased, Blood Urea Increased, Altered State Of Consciousness, Renal Impairment, Urine Output Decreased, Renal Failure Acute, Muscular Weakness (8201533-2)
Patient was taking Alfarol. Directly after, patient experienced the unwanted or unexpected Alfarol side effects: blood sodium increased, blood potassium increased, blood creatinine increased, blood urea increased, altered state of consciousness, renal impairment, urine output decreased, renal failure acute, muscular weakness on Mar 06, 2012 from JAPAN Additional patient health information: Female , weighting 138.9 lb, was diagnosed with
  • osteoporosis
  • hypertension
  • diabetes mellitus
  • constipation
and. Alfarol dosage: 1mcg Per Day.
Associated medications used:
  • Micardis (40mg Per Day)
  • Metformin Hcl
  • Alosenn (1g Per Day)
  • Adona (ac-17) (90mg Per Day)
  • Gabapentin (400mg Per Day)
  • Circuletin (75mg Per Day)
  • Livalo (2mg Per Day)
  • Valtrex (3000mg Per Day)


Feeling Abnormal, Feeling Hot, Flushing, Terminal Dribbling, Pain, Hepatitis, Rash, Dizziness, Insomnia (8199440-7)
Adverse event was reported on Feb 27, 2012 by a Female taking Alfarol (Dosage: Unk) . Location: JAPAN , 78 years of age, Patient felt the following Alfarol side effects: feeling abnormal, feeling hot, flushing, terminal dribbling, pain, hepatitis, rash, dizziness, insomnia.
Multiple prescriptions taken:
  • Hydrochlorothiazide (Unk)
  • Forteo (Unk)
  • Prednisolone (Unk)
  • Depas (Unk)
  • Olmesartan Medoxomil (Unk)
  • Clinoril
  • Rabeprazole Sodium (Unk)
  • Lyrica (Unk)


Hypoaesthesia, Hypocalcaemia, Blood Calcium Decreased, Tetany (8175230-6)
on Feb 16, 2012 Female from JAPAN , 38 years of age, was treated with Alfarol (alfacalcidol). After Alfarol was administered, patient encountered several Alfarol side effects: hypoaesthesia, hypocalcaemia, blood calcium decreased, tetany. Alfarol (alfacalcidol) dosage: N/A.
Multiple concurrent drugs taken:
  • Calciuim (calcium)
  • Actonel (17.5 Mg Once Daily, Oral)
  • Actonel (17.5 Mg Once Daily, Oral)


Purulent Discharge, Paralysis, Blood Albumin Decreased, No Therapeutic Response, Osteomyelitis, Facial Pain, Inflammation, Exposed Bone In Jaw, Swelling Face (8118759-9)
on Jan 24, 2012 Female from JAPAN , 84 years of age, was treated with Alfarol (alfacalcidol). Directly after, patient experienced the unwanted or unexpected Alfarol side effects: purulent discharge, paralysis, blood albumin decreased, no therapeutic response, osteomyelitis, facial pain, inflammation, exposed bone in jaw, swelling face. Alfarol (alfacalcidol) dosage: N/A.
Associated medications used:
  • Risedronate Sodium (Oral)
  • Ferromia (ferrous Sodiulm Citrate)
  • Etodolac
  • Bufferin
  • Tizanin (tizanidine Hydrochloride)
  • Blopress (candesartan Cilexetil)
  • Diart (azosemide)
  • Tenormin
Patient was hospitalized.

Liver Disorder (7936706-7)
Patient was taking Alfarol. Patient felt the following Alfarol side effects: liver disorder on Nov 11, 2011 from JAPAN Additional patient health information: Female , weighting 130.7 lb, . Alfarol dosage: 0.5 Mcg, Qd.
Multiple prescriptions taken:
  • Cinacalcet Hydrochloride (25 Mg, Qd)
  • Renagel (0.5 G, Tid)
Patient was hospitalized.

Nephrolithiasis, Hydronephrosis (7921348-X)
Adverse event was reported on Nov 08, 2011 by a Male taking Alfarol (Dosage: From:peroral Agent, Dosage Is Uncertain) . Location: JAPAN , weighting 103.6 lb, After Alfarol was administered, patient encountered several Alfarol side effects: nephrolithiasis, hydronephrosis.
Multiple concurrent drugs taken:
  • Actemra
  • Actemra
  • Adrenal Hormone Preparation (unk Ingredients) (Form: Peroral Agent)
  • Actemra
Patient was hospitalized.

Post Procedural Infection, Cholelithiasis (7919150-8)
on Nov 07, 2011 Female from JAPAN , weighting 132.3 lb, was treated with Alfarol. Directly after, patient experienced the unwanted or unexpected Alfarol side effects: post procedural infection, cholelithiasis. Alfarol dosage: N/A.
Associated medications used:
  • Amlodipine
  • Rhythmy (Single Use)
  • Diazepam (Single Use)
  • Actemra
  • Zantac
  • Morphine Hcl Elixir
  • Motilium
  • Ketoprofen
Patient was hospitalized.

Liver Disorder (7913328-5)
on Nov 01, 2011 Female from JAPAN , 59 years of age, was treated with Alfarol. Patient felt the following Alfarol side effects: liver disorder. Alfarol dosage: Uncertainty.
Multiple prescriptions taken:
  • Cinacalcet Hydrochloride (Unk)
  • Renagel (Uncertainty)
Patient was hospitalized.

Lymph Node Tuberculosis (7789564-8)
Patient was taking Alfarol. After Alfarol was administered, patient encountered several Alfarol side effects: lymph node tuberculosis on Sep 20, 2011 from JAPAN Additional patient health information: Male , 31 years of age, weighting 132.3 lb, was diagnosed with
  • prophylaxis
  • ankylosing spondylitis
and. Alfarol dosage: 0.25 Rg Daily.
Multiple concurrent drugs taken:
  • Remicade
  • Isoniazid (100df)
  • Isoniazid (200df)
  • Calcium Carbonate
  • Isoniazid (50df)
  • Tamiflu
  • Isoniazid (300df)
  • Pydoxal
Patient was hospitalized.

Arrhythmia (7759789-6)
Adverse event was reported on Aug 02, 2011 by a Female taking Alfarol (Dosage: 0.25 Mug, Qd) was diagnosed with
  • osteoporosis
  • gastritis
  • iron deficiency anaemia
  • cardiac failure
  • idiopathic thrombocytopenic purpura
  • thrombocytopenia
and. Location: JAPAN , 40 years of age, Directly after, patient experienced the unwanted or unexpected Alfarol side effects: arrhythmia.
Associated medications used:
  • Lansoprazole (30 Mg, Prn)
  • Ferrous Citrate (50 Mg, Qd)
  • Carvedilol (2.5 Mg, Bid)
  • Romiplostim (8 Mug/kg, Qwk)
  • Prednisolone (5 Mg, Qd)
  • Tambocor (50 Mg, Bid)
  • Pimenol (50 Mg, Bid)
Patient was hospitalized.

Skin Ulcer, Pneumonia Pneumococcal, Pleurisy, Loss Of Consciousness (7743002-X)
on Sep 01, 2011 Female from JAPAN , weighting 114.6 lb, was treated with Alfarol. Patient felt the following Alfarol side effects: skin ulcer, pneumonia pneumococcal, pleurisy, loss of consciousness. Alfarol dosage: N/A.
Multiple prescriptions taken:
  • Loxonin
  • Risedronate Sodium
  • Azulfidine
  • Prednisolone
  • Solu-medrol (Start Date And End Date: 29 March 2011)
  • Solu-medrol (Start Date And End Date: 31 March 2011)
  • Juvela (Form: Peroral Agent)
  • Solu-medrol (Start Date And End Date: 30 March 2011)
Patient was hospitalized.

Altered State Of Consciousness, Hyponatraemia, Vomiting, Dyskinesia, Headache (7737294-0)
on Aug 30, 2011 Female from JAPAN , 68 years of age, weighting 112.4 lb, was diagnosed with
  • osteoporosis
and was treated with Alfarol. After Alfarol was administered, patient encountered several Alfarol side effects: altered state of consciousness, hyponatraemia, vomiting, dyskinesia, headache. Alfarol dosage: N/A.
Multiple concurrent drugs taken:
  • Succinylcholine Chloride Inj
  • Atarax
  • Evista
  • Tsumura Daikentyuto
  • Diprivan
  • Potassium Chloride
  • Pantosin
  • Soft Santear
Patient was hospitalized.

Femur Fracture (7734649-5)
Patient was taking Alfarol. Directly after, patient experienced the unwanted or unexpected Alfarol side effects: femur fracture on Aug 31, 2011 from JAPAN Additional patient health information: Female , 76 years of age, was diagnosed with
  • osteoporosis
and. Alfarol dosage: N/A.
Associated medications used:
  • Pyridoxal Phosphate
  • Kenton (vitamin E Nicotinate)
  • Prednisolone
  • Mecobalamin
  • Fosamax
  • Metalcaptase
  • Dorner
  • Lipitor
Patient was hospitalized.

Cerebral Haemorrhage (7693886-9)
Adverse event was reported on Aug 17, 2011 by a Female taking Alfarol (Dosage: 0.25 Mg) . Location: JAPAN , 61 years of age, Patient felt the following Alfarol side effects: cerebral haemorrhage.
Multiple prescriptions taken:
  • Rabeprazole Sodium (10 Mg)
  • Exforge
  • Lasix (40 Mg)
  • Fosrenol (1500 Mg)
  • Calcium Compounds And Preparations (2000 Mg)
  • Tranexamic Acid (2250 Mg)
  • Pradaxa (220 Mg)
  • Doxazosin Mesylate (2 Mg)


Aspartate Aminotransferase Increased, Blood Potassium Decreased, Condition Aggravated, Cardiac Failure, Blood Bilirubin Increased, Hepatic Function Abnormal, Blood Sodium Increased, Alanine Aminotransferase Increased (7690306-5)
on Aug 01, 2011 Female from JAPAN , 73 years of age, weighting 115.5 lb, was treated with Alfarol (alfacalcidol). After Alfarol was administered, patient encountered several Alfarol side effects: aspartate aminotransferase increased, blood potassium decreased, condition aggravated, cardiac failure, blood bilirubin increased, hepatic function abnormal, blood sodium increased, alanine aminotransferase increased. Alfarol (alfacalcidol) dosage: N/A.
Multiple concurrent drugs taken:
  • Cetapril (alacepril)
  • Allopurinol
  • Acardi (pimobendan)
  • Mexitil
  • Aldactone
  • Amaryl
  • Zantac
  • Prednisolone (prednisolone Sodium Phosphate)


Acute Disseminated Encephalomyelitis, Urinary Tract Infection, Lumbar Spinal Stenosis, Disseminated Intravascular Coagulation, Blood Phosphorus Decreased, Platelet Count Decreased, Temperature Intolerance, Blood Potassium Decreased, Tinnitus (7679827-9)
on Aug 03, 2011 Female from JAPAN , 70 years of age, weighting 83.78 lb, was treated with Alfarol. Directly after, patient experienced the unwanted or unexpected Alfarol side effects: acute disseminated encephalomyelitis, urinary tract infection, lumbar spinal stenosis, disseminated intravascular coagulation, blood phosphorus decreased, platelet count decreased, temperature intolerance, blood potassium decreased, tinnitus. Alfarol dosage: Unk.
Associated medications used:
  • Fosamax (Unk)
  • Aspara-ca (Unk)
  • Prelone (Unk)
  • Prograf (Unk)
  • Prograf (Unk)
  • Enbrel (50 Mg, Qwk)
  • Rheumatrex (Unk)
  • Loxonin (Unk)
Patient was hospitalized.

Showing 1-25 of 44 

Alfarol Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Alfarol Information

More About Alfarol

Side Effects reported to FDA: 44. View Alfarol Adverse Reports

Alfarol safety alerts: No

Reported deaths: 5

Reported hospitalizations: 25

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