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Alkeran Side Effects

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Alkeran Safety Reports reported to FDA

Total Alkeran reports: 140.
Alkeran FDA safety alerts: No.
Reported deaths: 27    Reported hospitalizations: 73.
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Reported Alkeran Side Effects: febrile neutropenia, pyrexia, osteonecrosis, sepsis, stomatitis, cystitis haemorrhagic, anaemia, diarrhoea, pneumonia respiratory syncytial viral, bone marrow failure, abdominal pain.
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Alkeran Side Effects Report #5154015-9
Physician from JAPAN reported ALKERAN problem on Nov 02, 2006. Female patient, 54 years of age, weighting 105.8 lb, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: jaundice, lymphadenopathy, renal failure, retroperitoneal neoplasm. ALKERAN dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, TACROLIMUS HYDRATE, METHOTREXATE, FAMOTIDINE, ALLOPURINOL, LEVOFLOXACIN, DIFLUCAN, MODACIN. Patient was hospitalized. Patient died on 02/02/2005.

Alkeran Side Effects Report #5156310-6
ALKERAN problem was reported by a Physician from JAPAN on Jan 27, 2006. Male patient, child 6 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia, hepatic vein occlusion, mucous membrane disorder, recurrent cancer, venoocclusive liver disease. ALKERAN dosage: unknown. During the same period patient was treated with THIOTEPA. Patient died on 12/01/2004.

Alkeran Side Effects Report #5156319-2
Physician from JAPAN reported ALKERAN problem on Oct 03, 2006. Male patient was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: haematuria. ALKERAN dosage: 165MG CUMULATIVE DOSE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5157496-X
ALKERAN problem was reported by a Physician from JAPAN on Jan 27, 2006. Male patient, 19 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia. ALKERAN dosage: unknown. During the same period patient was treated with THIOTEPA. Patient recovered.

Alkeran Side Effects Report #5157497-1
Physician from JAPAN reported ALKERAN problem on Jan 27, 2006. Female patient, 14 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: herpes zoster, microangiopathic haemolytic anaemia, pyrexia, sepsis. ALKERAN dosage: unknown. During the same period patient was treated with THIOTEPA. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5157498-3
ALKERAN problem was reported by a Physician from JAPAN on Jan 27, 2006. Female patient, 13 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia. ALKERAN dosage: unknown. During the same period patient was treated with THIOTEPA. Patient recovered.

Alkeran Side Effects Report #5158698-9
Physician from GERMANY reported ALKERAN problem on Aug 21, 2006. Female patient, 70 years of age, weighting 167.6 lb, was diagnosed with plasmacytoma, multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: dental treatment, osteonecrosis, swelling, x-ray abnormal. ALKERAN dosage: 23 MG 6 TIMES A WEEK. During the same period patient was treated with PREDNISOLONE, BENDAMUSTINE, ZOMETA. Patient recovered.

Alkeran Side Effects Report #5163717-X
ALKERAN problem was reported by a Physician from JAPAN on Dec 28, 2005. Male patient, 58 years of age, weighting 101.4 lb, was diagnosed with stem cell transplant, non-hodgkin's lymphoma, prophylaxis, antifungal prophylaxis, infection prophylaxis, sepsis and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cystitis haemorrhagic, diarrhoea, haematuria, urinary retention. ALKERAN dosage: 60MG PER DAY. During the same period patient was treated with FLUDARA, KYTRIL, PROGRAF, BETAMETHASONE PHOSPHATE, GLYCEOL, FUNGUARD, VENOGLOBULIN, MAXIPIME. Patient was hospitalized. Patient died on 03/31/2006.

Alkeran Side Effects Report #5165483-0
Consumer or non-health professional from FRANCE reported ALKERAN problem on Nov 24, 2006. Male patient, 91 years of age, weighting 112.4 lb, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: osteonecrosis, scintigraphy, tooth infection. ALKERAN dosage: unknown. During the same period patient was treated with CORTANCYL, DEXAMETHASONE, ZOMETA. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5165580-X
ALKERAN problem was reported by a Physician from JAPAN on Sept 15, 2006. Male patient, 77 years of age, weighting 94.80 lb, was diagnosed with multiple myeloma, osteoporosis, gastritis, supraventricular tachycardia, angina pectoris, benign prostatic hyperplasia, lumbar vertebral fracture and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anaemia, cystitis haemorrhagic. ALKERAN dosage: 4MG PER DAY. During the same period patient was treated with PREDONINE, PRIMOBOLAN, ZANTAC, DIGOXIN, AMLODIPINE BESYLATE, MEVALOTIN, HARNAL, MOBIC. Patient was hospitalized. Patient died on 11/09/2006.

Alkeran Side Effects Report #5165584-7
Physician from JAPAN reported ALKERAN problem on Nov 27, 2006. Male patient, 65 years of age, weighting 108.0 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: blister, blood pressure decreased, c-reactive protein increased, pain, pyrexia, rash, septic shock, stomatitis, varicella. ALKERAN dosage: 100MG PER DAY. During the same period patient was treated with BENET, OMEPRAZOLE, DIFLUCAN, GASTER D. Patient recovered.

Alkeran Side Effects Report #5168961-3
ALKERAN problem was reported by a Physician from JAPAN on Dec 04, 2006. Female patient, 53 years of age, weighting 125.7 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anorexia, blood albumin decreased, diarrhoea, febrile neutropenia. ALKERAN dosage: 150MG PER DAY. During the same period patient was treated with NEUTROGIN, KEITEN, ZOVIRAX, FUNGUARD, CARBENIN, FULCALIQ. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5169984-0
Physician from JAPAN reported ALKERAN problem on Mar 03, 2006. Male patient, 76 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: cardiac disorder, cardiac failure. ALKERAN dosage: unknown. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5169997-9
ALKERAN problem was reported by a Physician from JAPAN on Dec 04, 2006. Male patient, 48 years of age, weighting 145.5 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: alanine aminotransferase increased, anorexia. ALKERAN dosage: 150MG PER DAY. During the same period patient was treated with NEUTROGIN, ALESION, ZOVIRAX, CIPROFLOXACIN, FLUCONAZOLE, BACTRIM, GASTER D, FULCALIQ. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5169998-0
Physician from JAPAN reported ALKERAN problem on Dec 04, 2006. Male patient, 55 years of age, weighting 152.1 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain, alanine aminotransferase increased, febrile neutropenia. ALKERAN dosage: 175MG PER DAY. During the same period patient was treated with NEUTROGIN, CIPROFLOXACIN, FLUCONAZOLE, ZOVIRAX, GASTER D, FUNGUARD, MAXIPIME, MEROPEN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5173823-1
ALKERAN problem was reported by a Physician from JAPAN on Nov 27, 2006. Male patient, 65 years of age, weighting 108.0 lb, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: blister, blood pressure decreased, c-reactive protein increased, pain, pyrexia, rash, septic shock, stomatitis, varicella. ALKERAN dosage: 100MGM2 PER DAY. During the same period patient was treated with BENET, OMEPRAZOLE, DIFLUCAN, GASTER D, EFONIDIPINE HYDROCHLORIDE. Patient recovered.

Alkeran Side Effects Report #5173839-5
Physician from JAPAN reported ALKERAN problem on Dec 11, 2006. Female patient, child 10 years of age, was diagnosed with bone marrow conditioning regimen and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: capillary leak syndrome. ALKERAN dosage: 100MGM2 PER DAY. During the same period patient was treated with PARAPLATIN, ETOPOSIDE. Patient died on 11/15/2005.

Alkeran Side Effects Report #5188266-4
ALKERAN problem was reported by a Pharmacist from FRANCE on Nov 24, 2006. Male patient, 49 years of age, weighting 163.1 lb, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: blood bilirubin increased, coombs test negative, haemolytic anaemia, haptoglobin decreased, intravascular haemolysis. ALKERAN dosage: 256MG PER DAY. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5190019-8
Physician from JAPAN reported ALKERAN problem on Dec 05, 2006. Male patient, 19 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: brain herniation, disease recurrence, febrile neutropenia. ALKERAN dosage: 70 MG/M2 / PER DAY / INTRAVENOUS. During the same period patient was treated with THIOTEPA. Patient recovered.

Alkeran Side Effects Report #5190022-8
ALKERAN problem was reported by a Physician from JAPAN on Dec 05, 2006. Female patient, 14 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: febrile neutropenia. ALKERAN dosage: 70 MG/M2/ PER DAY / INTRAVENOUS. During the same period patient was treated with THIOTEPA. Patient recovered.

Alkeran Side Effects Report #5190023-X
Physician from JAPAN reported ALKERAN problem on Dec 05, 2006. Male patient, child 7 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anal stenosis, febrile neutropenia, mucous membrane disorder, venoocclusive liver disease. ALKERAN dosage: 70 MG/M2 / PER DAY / INTRAVENOUS. During the same period patient was treated with THIOTEPA. Patient recovered.

Alkeran Side Effects Report #5190024-1
ALKERAN problem was reported by a Physician from JAPAN on Dec 05, 2006. Female patient, 14 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: herpes zoster, microangiopathic haemolytic anaemia, staphylococcal sepsis, thrombotic microangiopathy. ALKERAN dosage: 70 MG/M2 / PER DAY / INTRAVENOUS. During the same period patient was treated with THIOTEPA. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5191743-3
Consumer or non-health professional from ITALY reported ALKERAN problem on Dec 06, 2006. Male patient, 58 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: hypoaesthesia, osteonecrosis. ALKERAN dosage: 200 MG/M2. During the same period patient was treated with VINCRISTINE, DOXORUBICIN HYDROCHLORIDE, DEXAMETHASONE, HEMATOPOETIC PROGENITOR CELLS. Patient recovered.

Alkeran Side Effects Report #5191744-5
ALKERAN problem was reported by a Consumer or non-health professional from ITALY on Dec 06, 2006. Female patient, 65 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: local swelling, osteonecrosis, pain, skin odour abnormal. ALKERAN dosage: unknown. During the same period patient was treated with PREDNISOLONE, DEXAMETHASONE, DOXORUBICIN HYDROCHLORIDE. Patient recovered.

Alkeran Side Effects Report #5191745-7
Consumer or non-health professional from ITALY reported ALKERAN problem on Dec 06, 2006. Female patient, 52 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: osteonecrosis. ALKERAN dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN HYDROCHLORIDE, DEXAMETHASONE, HEMATOPOETIC PROGENITOR CELLS. Patient recovered.

Alkeran Side Effects Report #5191753-6
ALKERAN problem was reported by a Consumer or non-health professional from ITALY on Dec 06, 2006. Female patient, 80 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: actinomycosis, localised oedema, osteomyelitis, osteonecrosis, secretion discharge, skin odour abnormal. ALKERAN dosage: unknown. During the same period patient was treated with PREDNISOLONE, CYCLOPHOSPHAMIDE, DEXAMETHASONE. Patient recovered.

Alkeran Side Effects Report #5191754-8
Consumer or non-health professional from ITALY reported ALKERAN problem on Dec 06, 2006. Male patient, 66 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: actinomycosis, osteomyelitis, osteonecrosis. ALKERAN dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.

Alkeran Side Effects Report #5191755-X
ALKERAN problem was reported by a Consumer or non-health professional from ITALY on Dec 06, 2006. Male patient, 58 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: osteonecrosis, skin odour abnormal, swelling. ALKERAN dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.

Alkeran Side Effects Report #5191756-1
Consumer or non-health professional from ITALY reported ALKERAN problem on Dec 06, 2006. Female patient, 44 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: hypoaesthesia, osteonecrosis. ALKERAN dosage: 200 MG/M2. During the same period patient was treated with VINCRISTINE, DOXORUBICIN HYDROCHLORIDE, DEXAMETHASONE, ZOLEDRONATE, THALIDOMIDE, HEMATOPOETIC PROGENITOR CELLS. Patient recovered.

Alkeran Side Effects Report #5191757-3
ALKERAN problem was reported by a Consumer or non-health professional from ITALY on Dec 06, 2006. Female patient, 71 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: impaired healing, osteonecrosis. ALKERAN dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.

Alkeran Side Effects Report #5191758-5
Consumer or non-health professional from ITALY reported ALKERAN problem on Dec 06, 2006. Female patient, 80 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: impaired healing, osteonecrosis. ALKERAN dosage: unknown. During the same period patient was treated with PREDNISOLONE. Patient recovered.

Alkeran Side Effects Report #5392416-4
ALKERAN problem was reported by a Physician from JAPAN on July 17, 2007. Female patient, child 10 years of age, was diagnosed with stem cell transplant and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: convulsion, dizziness. ALKERAN dosage: unknown. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, BAKTAR, DIFLUCAN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE. Patient was hospitalized and became disabled. Patient recovered.

Alkeran Side Effects Report #5401376-9
Physician from JAPAN reported ALKERAN problem on July 24, 2007. Female patient, child 10 years of age, weighting 51.15 lb, was diagnosed with stem cell transplant, sedation, infection prophylaxis and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, bedridden, convulsion, dizziness, dysstasia, fatigue, loss of consciousness, muscular weakness, photosensitivity reaction. ALKERAN dosage: 55MG PER DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE, BAKTAR, DIFLUCAN, KYTRIL, HEPARIN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5418270-X
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Aug 08, 2007. Male patient, 76 years of age, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: dermatitis exfoliative, eczema, impetigo, pruritus, skin disorder, staphylococcal sepsis. ALKERAN dosage: unknown. During the same period patient was treated with ZOMETA, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5419431-6
Physician from JAPAN reported ALKERAN problem on Aug 14, 2007. Female patient, child 10 years of age, weighting 51.15 lb, was diagnosed with stem cell transplant, dermatitis atopic, sedation, infection prophylaxis and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, bedridden, convulsion, dizziness, dysstasia, fatigue, loss of consciousness, muscular weakness, pupillary light reflex tests abnormal. ALKERAN dosage: 55MG PER DAY. During the same period patient was treated with FLUDARABINE PHOSPHATE, ZADITEN, HYDROXYZINE PAMOATE, PENTAZOCINE LACTATE, BAKTAR, DIFLUCAN, KYTRIL, HEPARIN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5424974-5
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Aug 13, 2007. Male patient, 61 years of age, was diagnosed with transplant, febrile bone marrow aplasia and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: anuria, blood creatinine increased, confusional state, disorientation, febrile bone marrow aplasia, haemodialysis, oedema peripheral, oliguria. ALKERAN dosage: 200MG PER DAY. During the same period patient was treated with AMIKLIN, LASIX, CIPROFLOXACIN, ALLOPURINOL, TAZOCILLINE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5448735-6
Pharmacist from JAPAN reported ALKERAN problem on Sept 07, 2007. Male patient, weighting 136.7 lb, was diagnosed with multiple myeloma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: abdominal pain upper, angina pectoris, headache, interstitial lung disease, pyrexia, upper respiratory tract inflammation. ALKERAN dosage: unknown. During the same period patient was treated with ASPIRIN, RABEPRAZOLE, FRANDOL S, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5451427-0
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 03, 2007. Male patient, 57 years of age, was diagnosed with prophylaxis of nausea and vomiting and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, cardiac disorder, cholestasis, hepatosplenomegaly, hyperthermia, liver function test abnormal, lung neoplasm, oxygen saturation decreased, pancytopenia. ALKERAN dosage: 280MG SINGLE DOSE. During the same period patient was treated with RITUXAN, ZEVALIN, ETOPOSIDE, CYTARABINE, BICNU, KEPIVANCE, HEPARIN, ZOFRAN. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5453880-5
Physician from JAPAN reported ALKERAN problem on Sept 13, 2007. Male patient, 43 years of age, weighting 132.3 lb, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: melaena. ALKERAN dosage: 100MG PER DAY. During the same period patient was treated with NEUTROGIN, TACROLIMUS HYDRATE, METHOTREXATE, PREDONINE, ITRIZOLE, MUCODYNE. Patient recovered.

Alkeran Side Effects Report #5471011-2
ALKERAN problem was reported by a Consumer or non-health professional from FRANCE on Sept 17, 2007. Male patient, 76 years of age, was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: dermatitis exfoliative, eczema, impetigo, photosensitivity reaction, pruritus, skin disorder, staphylococcal sepsis, t-cell lymphoma, toxic skin eruption. ALKERAN dosage: unknown. During the same period patient was treated with ZOMETA, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

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