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Severe Pain Lower Abdomen (23)
Nausea (22)
Rashes (22)
Bad Diarrhoea (16)
Vomiting (15)
Cramps (14)
Bloating (11)
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Amoclav Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Crying, Nausea, Lethargy, Nightmare (7905186-X)
on Nov 02, 2011 Male from IRELAND , 24 years of age, weighting 260.1 lb, was diagnosed with
  • infected dermal cyst
  • respiratory tract infection
and was treated with Amoclav. Directly after, patient experienced the unwanted or unexpected Amoclav side effects: crying, nausea, lethargy, nightmare. Amoclav dosage: Daily Dose 1875 Mg.
Associated medications used:
  • Avelox (Daily Dose 400 Mg)


Abdominal Pain, Blood Pressure Immeasurable, Circulatory Collapse, Dehydration, Diarrhoea, Haematochezia (6556449-4)
Patient was taking Amoclav. Patient felt the following Amoclav side effects: abdominal pain, blood pressure immeasurable, circulatory collapse, dehydration, diarrhoea, haematochezia on Jan 25, 2010 from GERMANY Additional patient health information: Female , 85 years of age, weighting 154.3 lb, was diagnosed with
  • erysipelas
and. Amoclav dosage: 1000mg Twice Per Day.
Multiple prescriptions taken:
  • Ampicillin And Sulbactam (3g Per Day)
  • Beloc Zok (47.5mg Twice Per Day)
  • Ramipril (2.5mg Per Day)
  • Stangyl (25mg Per Day)
  • Simvastatin (40mg Per Day)
  • Aspirin (100mg Per Day)
Patient was hospitalized.

Toxic Epidermal Necrolysis (6216991-2)
Adverse event was reported on May 29, 2009 by a Female taking Amoclav (amoxicillin, Clavulanate) Film-coated (Dosage: 1 Df, Bid, Oral) was diagnosed with
  • skin lesion
and. Location: GERMANY , 94 years of age, weighting 109.1 lb, After Amoclav was administered, patient encountered several Amoclav side effects: toxic epidermal necrolysis.
Multiple concurrent drugs taken:
  • Oxazepam
  • Ramipril


Toxic Epidermal Necrolysis (6214811-3)
on Jun 02, 2009 Female from GERMANY , 94 years of age, weighting 109.1 lb, was diagnosed with
  • skin lesion
  • sleep disorder
and was treated with Amoclav. Directly after, patient experienced the unwanted or unexpected Amoclav side effects: toxic epidermal necrolysis. Amoclav dosage: 1000mg Twice Per Day.
Associated medications used:
  • Oxazepam
  • Ramipril (10mg Per Day)



Rheumatoid Arthritis (5612635-9)
on Jan 31, 2008 Female from GERMANY , 67 years of age, was diagnosed with
  • pneumonia
and was treated with Amoclav. Patient felt the following Amoclav side effects: rheumatoid arthritis. Amoclav dosage: N/A.

Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Alkaline Phosphatase Increased, Blood Cholesterol Increased, Diarrhoea, Gamma-glutamyltransferase Increased, Glutamate Dehydrogenase Increased, Hyperbilirubinaemia, Jaundice (5409314-X)
Patient was taking Amoclav (ngx)(amoxicillin, Clavulanate) Film-coated Tablet, 875/125mg. After Amoclav was administered, patient encountered several Amoclav side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood cholesterol increased, diarrhoea, gamma-glutamyltransferase increased, glutamate dehydrogenase increased, hyperbilirubinaemia, jaundice on Jul 31, 2007 from GERMANY Additional patient health information: Male , 55 years of age, weighting 185.2 lb, was diagnosed with
  • bronchitis
and. Amoclav (ngx)(amoxicillin, Clavulanate) Film-coated Tablet, 875/125mg dosage: 875/125 Mg, Bid, Oral.

Bilirubin Conjugated Increased, Blood Alkaline Phosphatase Increased, Blood Cholesterol Increased, Blood Lactate Dehydrogenase Increased, Diarrhoea, Gamma-glutamyltransferase Increased, Hepatic Enzyme Increased, Hyperbilirubinaemia, Jaundice (5406076-7)
Adverse event was reported on Aug 01, 2007 by a Male taking Amoclav (Dosage: 1000mg Twice Per Day) . Location: GERMANY , 55 years of age, Directly after, patient experienced the unwanted or unexpected Amoclav side effects: bilirubin conjugated increased, blood alkaline phosphatase increased, blood cholesterol increased, blood lactate dehydrogenase increased, diarrhoea, gamma-glutamyltransferase increased, hepatic enzyme increased, hyperbilirubinaemia, jaundice.

Diarrhoea Haemorrhagic (5355633-5)
on Jun 04, 2007 Female from GERMANY , 40 years of age, was treated with Amoclav. Patient felt the following Amoclav side effects: diarrhoea haemorrhagic. Amoclav dosage: N/A.

Amnesia, Areflexia, Loss Of Consciousness (5284427-4)
on Mar 20, 2007 Female from GERMANY , 66 years of age, was diagnosed with
  • osteitis
and was treated with Amoclav (ngx) (amoxicillin, Clavulanate) Film-coated Tablet. After Amoclav was administered, patient encountered several Amoclav side effects: amnesia, areflexia, loss of consciousness. Amoclav (ngx) (amoxicillin, Clavulanate) Film-coated Tablet dosage: Oral. Patient was hospitalized.

Aggression, Restlessness (5281784-X)
Patient was taking Amoclav. Directly after, patient experienced the unwanted or unexpected Amoclav side effects: aggression, restlessness on Mar 27, 2007 from GERMANY Additional patient health information: Female , 51 years of age, . Amoclav dosage: 625mg Three Times Per Day.
Associated medications used:
  • Levothyroxine Sodium


Amnesia, Areflexia, Loss Of Consciousness (5277288-0)
Adverse event was reported on Mar 22, 2007 by a Female taking Amoclav (Dosage: N/A) . Location: GERMANY , 66 years of age, Patient felt the following Amoclav side effects: amnesia, areflexia, loss of consciousness. Patient was hospitalized.

Cholestasis (5086597-X)
on Mar 17, 2006 Female from GERMANY , 36 years of age, was diagnosed with
  • bronchopneumonia
and was treated with Amoclav. After Amoclav was administered, patient encountered several Amoclav side effects: cholestasis. Amoclav dosage: 625mg Per Day. Patient was hospitalized.

Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Blood Lactate Dehydrogenase Increased, Cholestasis, Gamma-glutamyltransferase Increased (5086596-8)
on Mar 07, 2006 Female from GERMANY , 36 years of age, was diagnosed with
  • bronchopneumonia
and was treated with Amoclav. Directly after, patient experienced the unwanted or unexpected Amoclav side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, cholestasis, gamma-glutamyltransferase increased. Amoclav dosage: 625mg Per Day. Patient was hospitalized.

Cholelithiasis (4951758-4)
Patient was taking Amoclav. Patient felt the following Amoclav side effects: cholelithiasis on Mar 17, 2006 from GERMANY Additional patient health information: Female , 36 years of age, was diagnosed with
  • bronchopneumonia
and. Amoclav dosage: 625mg Per Day. Patient was hospitalized.

Dermatitis Bullous, Dysphagia, Dyspnoea, Oral Mucosal Blistering (4947817-2)
Adverse event was reported on Mar 17, 2006 by a Male taking Amoclav (Dosage: 1000mg Twice Per Day) was diagnosed with
  • tonsillitis
and. Location: GERMANY , 20 years of age, weighting 180.8 lb, After Amoclav was administered, patient encountered several Amoclav side effects: dermatitis bullous, dysphagia, dyspnoea, oral mucosal blistering.

Aggression, Insomnia, Psychomotor Hyperactivity (4893741-3)
on Jan 16, 2006 Male from GERMANY , child 5 years of age, was diagnosed with
  • sinusitis
and was treated with Amoclav. Directly after, patient experienced the unwanted or unexpected Amoclav side effects: aggression, insomnia, psychomotor hyperactivity. Amoclav dosage: N/A.

Amoclav Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Amoclav Information

More About Amoclav

Side Effects reported to FDA: 16. View Amoclav Adverse Reports

Amoclav safety alerts: No

Reported deaths: 1

Reported hospitalizations: 5

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