PatientsVille.com Logo

PatientsVille

Antabuse Side Effects

Common Antabuse Side Effects


The most commonly reported Antabuse side effects (click to view or check a box to report):

Asthenia (8)
Coagulopathy (6)
Hypoaesthesia (5)
Jaundice (5)
Paraesthesia (5)
Malaise (5)
Disorientation (4)
Blood Alcohol Increased (4)
Dysstasia (4)
Delusion (4)
Gait Disturbance (4)
Encephalopathy (4)
Polyneuropathy (4)
Mental Status Changes (4)
Hypotension (4)
Insomnia (3)
Headache (3)
Coordination Abnormal (3)
Delirium (3)
Dyspnoea (3)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

Antabuse Side Effects Reported to FDA

The following Antabuse reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.


The appearance of Antabuse on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.
Sopor, Polyneuropathy, Myalgia
This is a report of a 45-year-old male patient (weight: NA) from IT, suffering from the following symptoms/conditions: alcoholism, who was treated with Antabuse (dosage: 800 Mg, Daily, start time: Jul 06, 2013), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
  • Sopor
  • Polyneuropathy
  • Myalgia
which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Antabuse treatment in male patients, resulting in sopor side effect. The patient was hospitalized.

Slow Response To Stimuli
This report suggests a potential Antabuse Slow Response To Stimuli side effect(s) that can have serious consequences. A 37-year-old male patient (weight: NA) from IT was diagnosed with the following symptoms/conditions: NA and used Antabuse (dosage: Unk) starting NS. Soon after starting Antabuse the patient began experiencing various side effects, including:
  • Slow Response To Stimuli
Drugs used concurrently:
  • Haldol /00027401/ (10 Mg/ml, Unk)
  • Tavor /00273201/ (Unk)
  • Keppra (Unk)
  • Alcover (Unk)
Although Antabuse demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as slow response to stimuli, may still occur.

Liver Function Test Abnormal, Abdominal Pain Upper, Paraesthesia, Fatigue, Chromaturia, Faeces Discoloured, Eye Colour Change, Abnormal Faeces
This Liver Function Test Abnormal, Abdominal Pain Upper, Paraesthesia, Fatigue, Chromaturia, Faeces Discoloured, Eye Colour Change, Abnormal Faeces problem was reported by a consumer or non-health professional from GB. A 58-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: abstains from alcohol,depression,gout. On NS this consumer started treatment with Antabuse (dosage: NA). The following drugs were being taken at the same time:
  • Citalopram
  • Allopurinol
When commencing Antabuse, the patient experienced the following unwanted symptoms/side effects:
  • Liver Function Test Abnormal
  • Abdominal Pain Upper
  • Paraesthesia
  • Fatigue
  • Chromaturia
  • Faeces Discoloured
  • Eye Colour Change
  • Abnormal Faeces
Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as liver function test abnormal, may become evident only after a product is in use by the general population.

Erythema, Anxiety, Menorrhagia, Polymenorrhoea
This is a report of a 25-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Antabuse (dosage: NA) starting Jan 01, 1999. Concurrently used drugs: NA.Soon after that, the consumer experienced the following side effects:
  • Erythema
  • Anxiety
  • Menorrhagia
  • Polymenorrhoea
This opens a possibility that Antabuse treatment could cause the above reactions, including erythema, and some female subjects may be more susceptible.


Ocular Icterus, Yellow Skin, Thinking Abnormal, Liver Disorder, Brain Oedema, Liver Transplant
A 39-year-old male patient (weight: NA) from US with the following symptoms/conditions: impaired driving ability,blood alcohol abnormal,legal problem started Antabuse -disulfiram- 250 Mg Getting Information treatment (dosage: 01/13/2012--04/13/2013 ?3 Months) on Jan 13, 2012. Soon after starting Antabuse -disulfiram- 250 Mg Getting Information treatment, the subject experienced various side effects, including:
  • Ocular Icterus
  • Yellow Skin
  • Thinking Abnormal
  • Liver Disorder
  • Brain Oedema
  • Liver Transplant
Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some male patients could be more vulnerable to Antabuse -disulfiram- 250 Mg Getting Information.

Myocardial Infarction
A 52-year-old male patient from SWEDEN (weight: NA) experienced symptoms, such as: NA and was treated with Antabuse(dosage: NA). The treatment was initiated on Jan 12, 2012. After that a consumer reported the following side effect(s):
  • Myocardial Infarction
Concurrently used drugs, which potentially could have contributed to side effect(s) or affected Antabuse efficacy:
  • Seroquel
  • Seroquel
  • Seroquel
  • Seroquel



In this report, Antabuse was administered for the following condition: NA.A 46-year-old male consumer from SPAIN (weight: NA) started Antabuse treatment (dosage: NA) on Feb 01, 2011.Sometime after starting the treatment, the patient complained of the following side effect(s):
    A possible interaction with other drugs could have contributed to this reaction:
    • Sedotime
    • Bupropion Hcl
    Establishing a causal relationship between a specific drug and consumer's side effects is complex, but it is possible that in this report Antabuse treatment could be related to the listed above side effect(s).

    Blood Alcohol Increased, Loss Of Consciousness
    This is a report of the following Antabuse side effect(s):
    • Blood Alcohol Increased
    • Loss Of Consciousness
    A 24-year-old female patient from UNITED STATES (weight: NA) presented with the following condition: NA and received a treatment with Antabuse (dosage: 500 Mg (250 Mg, 2 In 1 D)) starting: Aug 25, 2011.The following concurrently used drugs could have generated interactions: NA.This report suggests that a Antabuse treatment could be associated with the listed above side effect(s).

    Alcohol Interaction, Ketoacidosis
    This Antabuse report was submitted by a 40-year-old male consumer from UNITED STATES (weight: NA). The patient was diagnosed with: alcoholism and Antabuse was administered (dosage: NA) starting: NS. The consumer developed a set of symptoms:
    • Alcohol Interaction
    • Ketoacidosis
    Other drugs used simultaneously:
    • Ethanol
    Those unexpected symptoms could be linked to a Antabuse treatment, however establishing a potential drug-safety problem requires a more detailed clinical analysis.

    Ulna Fracture, Fall
    This is a report of a possible correlation between Antabuse use and the following symptoms/side effect(s):
    • Ulna Fracture
    • Fall
    which could contribute to an assessment of Antabuse risk profile.A 38-year-old male consumer from UNITED STATES (weight: NA) was suffering from investigation and was treated with Antabuse (dosage: 500 Mg, 1 Po) starting May 21, 2011.Other concurrent medications: NA.The patient was hospitalized.

    Phlebitis, Deep Vein Thrombosis
    A male patient from DENMARK (weight: NA) presented with the following symptoms: alcohol abuse,psoriasis and after a treatment with Antabuse (dosage: NA) experienced the following side effect(s):
    • Phlebitis
    • Deep Vein Thrombosis
    The treatment was started on Jun 01, 2008. Antabuse was used in combination with the following drugs:
    • Humira
    The patient was hospitalized.This report could alert potential Antabuse consumers.

    Phlebitis, Deep Vein Thrombosis
    In this report, a male patient from DENMARK (weight: NA) was affected by a possible Antabuse side effect.The patient was diagnosed with alcohol abuse,psoriasis. After a treatment with Antabuse (dosage: NA, start date: Jun 01, 2008), the patient experienced the following side effect(s):
    • Phlebitis
    • Deep Vein Thrombosis
    The following simultaneously used drugs could have led to this reaction:
    • Humira
    The patient was hospitalized.The findings here stress that side effects should be taken into consideration when evaluating a Antabuse treatment.

    Hepatitis, Encephalopathy
    This is a report of a 41-year-old male patient from UNITED STATES (weight: NA), who used Antabuse (dosage: 500mg Three Times Weekly Po) for a treatment of alcohol abuse. After starting a treatment on Jan 23, 2011, the patient experienced the following side effect(s):
    • Hepatitis
    • Encephalopathy
    The following drugs could possibly have interacted with the Antabuse treatment NA.The patient was hospitalized.Taken together, these observations suggest that a Antabuse treatment could be related to side effect(s), such as Hepatitis, Encephalopathy.

    White Blood Cell Count Increased, Dyspnoea, Oedema Peripheral, C-reactive Protein Increased, Weight Increased, Eosinophil Count Increased
    This white blood cell count increased side effect was reported by a health professional from DENMARK. A female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Antabuse (dosage: 800 Mg, Qw2), which was started on Oct 29, 2010. Concurrently used drugs:
    • Seroquel Xr (800 Mg Daily)
    • Venlafaxine (800 Mg Daily)
    • Leponex (250 Mg Daily)
    When starting to take Antabuse the consumer reported the following symptoms:
    • White Blood Cell Count Increased
    • Dyspnoea
    • Oedema Peripheral
    • C-reactive Protein Increased
    • Weight Increased
    • Eosinophil Count Increased
    The patient was hospitalized. These side effects may potentially be related to Antabuse.

    Depressed Level Of Consciousness, Weight Decreased, Disorientation, Pyrexia, Tobacco Abuse
    This is a Antabuse side effect report of a 36-year-old male patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: alcoholism, who was treated with Antabuse (dosage:NA, start time: NS), combined with:
    • Strattera
    • Colace
    • Buspar
    • Symmetrel
    • Zoloft
    • Cogentin
    • Invega Sustenna
    • Invega
    , and developed a serious reaction and a depressed level of consciousness side effect. The patient presented with:
    • Depressed Level Of Consciousness
    • Weight Decreased
    • Disorientation
    • Pyrexia
    • Tobacco Abuse
    which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Antabuse treatment in male patients suffering from alcoholism, resulting in depressed level of consciousness.

    Ileus Paralytic, Constipation
    This report suggests a potential Antabuse ileus paralytic side effect(s) that can have serious consequences. A 59-year-old male patient from DENMARK (weight:NA) was diagnosed with the following health condition(s): NA and used Antabuse (dosage: NA) starting NS. Soon after starting Antabuse the patient began experiencing various side effects, including:
    • Ileus Paralytic
    • Constipation
    Drugs used concurrently:
    • Lamotrigine
    • Seroquel
    • Effexor
    The patient was hospitalized. Although Antabuse demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as ileus paralytic, may still occur.

    Asthenia, Disorientation, Malaise, Neuropathy Peripheral, Paraesthesia
    This asthenia problem was reported by a consumer or non-health professional from UNITED STATES. A 49-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Antabuse (dosage: NA). The following drugs/medications were being taken at the same time: NA. When commencing Antabuse, the patient experienced the following unwanted symptoms /side effects:
    • Asthenia
    • Disorientation
    • Malaise
    • Neuropathy Peripheral
    • Paraesthesia
    Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as asthenia, may become evident only after a product is in use by the general population.

    Coagulopathy, Jaundice, Malaise, Mental Status Changes, Substance Abuse
    This is a Antabuse side effect report of a 40-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: alcohol abuse and was treated with Antabuse (dosage: Unk Unk Oral 047) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
    • Coagulopathy
    • Jaundice
    • Malaise
    • Mental Status Changes
    • Substance Abuse
    The patient was hospitalized. This opens a possibility that Antabuse could cause coagulopathy and that some female patients may be more susceptible.

    Abdominal Pain, Coagulopathy, Coma, Decreased Appetite, Jaundice, Liver Transplant, Malaise, Mental Status Changes
    A 23-year-old male patient (weight: NA) from UNITED STATES with the following symptoms: alcohol abuse started Antabuse treatment (dosage: 250 Mg Daily Oral 047) on NS. Soon after starting Antabuse treatment, the consumer experienced several side effects, including:
    • Abdominal Pain
    • Coagulopathy
    • Coma
    • Decreased Appetite
    • Jaundice
    • Liver Transplant
    • Malaise
    • Mental Status Changes
    . Concurrently used drugs: NA.The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Antabuse side effects, such as abdominal pain.

    Coagulopathy, Jaundice, Malaise, Mental Status Changes
    This coagulopathy side effect was reported by a health professional from UNITED STATES. A 39-year-old male patient (weight:NA) experienced the following symptoms/conditions: alcohol abuse.The patient was prescribed Antabuse (dosage: Unk Unk Oral 047), which was started on NS. Concurrently used drugs: NA..When starting to take Antabuse the consumer reported symptoms, such as:
    • Coagulopathy
    • Jaundice
    • Malaise
    • Mental Status Changes
    These side effects may potentially be related to Antabuse. The patient was hospitalized.

    Abdominal Pain, Arthralgia, Coagulopathy, Headache, Jaundice, Malaise, Mental Status Changes
    This is a report of a 36-year-old female patient (weight: NA) from UNITED STATES, suffering from the following symptoms/conditions: alcohol abuse, who was treated with Antabuse (dosage: Unk Daily Oral 047, start time: NS), combined with: NA. and developed a serious reaction and side effect(s). The consumer presented with:
    • Abdominal Pain
    • Arthralgia
    • Coagulopathy
    • Headache
    • Jaundice
    • Malaise
    • Mental Status Changes
    which developed after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Antabuse treatment in female patients, resulting in abdominal pain side effect. The patient was hospitalized.

    Asthenia, Confusional State, Hypoaesthesia, Neuropathy Peripheral, Paraesthesia
    This report suggests a potential Antabuse Asthenia, Confusional State, Hypoaesthesia, Neuropathy Peripheral, Paraesthesia side effect(s) that can have serious consequences. A 47-year-old female patient (weight: NA) from UNITED STATES was diagnosed with the following symptoms/conditions: alcohol abuse and used Antabuse (dosage: 250 Mg Once Daily Po) starting Aug 01, 2007. Soon after starting Antabuse the patient began experiencing various side effects, including:
    • Asthenia
    • Confusional State
    • Hypoaesthesia
    • Neuropathy Peripheral
    • Paraesthesia
    Drugs used concurrently: NA. Although Antabuse demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as asthenia, may still occur.

    Aggression, Alcohol Intolerance, Brain Injury, Disturbance In Attention, Impaired Work Ability, Insomnia, Mental Impairment, Nasal Polyps
    This Aggression, Alcohol Intolerance, Brain Injury, Disturbance In Attention, Impaired Work Ability, Insomnia, Mental Impairment, Nasal Polyps problem was reported by a consumer or non-health professional from UNITED STATES. A 33-year-old male patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On NS this consumer started treatment with Antabuse (dosage: NA). The following drugs were being taken at the same time: NA. When commencing Antabuse, the patient experienced the following unwanted symptoms/side effects:
    • Aggression
    • Alcohol Intolerance
    • Brain Injury
    • Disturbance In Attention
    • Impaired Work Ability
    • Insomnia
    • Mental Impairment
    • Nasal Polyps
    The patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as aggression, may become evident only after a product is in use by the general population.

    Breast Pain, Breath Odour, Hyperaesthesia, Lip Blister, Oral Pain, Paraesthesia
    This is a report of a 63-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: alcohol use and was treated with Antabuse (dosage: 250 Mg Daily Po) starting Jan 20, 2009. Concurrently used drugs: NA.Soon after that, the consumer experienced the following side effects:
    • Breast Pain
    • Breath Odour
    • Hyperaesthesia
    • Lip Blister
    • Oral Pain
    • Paraesthesia
    This opens a possibility that Antabuse treatment could cause the above reactions, including breast pain, and some female subjects may be more susceptible.

    Anxiety, Delusion, Dyspnoea, Fatigue, Fear, Heart Rate Increased, Hyperacusis
    A 31-year-old male patient (weight: NA) from GERMANY with the following symptoms/conditions: NA started Antabuse treatment (dosage: 250 Mg/day,) on NS. Soon after starting Antabuse treatment, the subject experienced various side effects, including:
    • Anxiety
    • Delusion
    • Dyspnoea
    • Fatigue
    • Fear
    • Heart Rate Increased
    • Hyperacusis
    Concurrently used drugs:
    • Cocaine(cocaine)
    This finding indicates that some male patients could be more vulnerable to Antabuse.

    1 of 2 



    Keep Track of Side Effects

    Note Your Observations

    It is really important to keep of your symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

    Why Your Notes are Important

    Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


    Discuss Antabuse Side Effects

    Did You Have a Antabuse Side Effect?

    Yes, Severe
    Yes, Moderate
    Yes, Minor
    No

    How Effective is Antabuse for You?

    Exceeded Expectations
    Effective
    Somewhat Effective
    Not Effective

    Antabuse Safety Alerts, Active Ingredients, Usage Information

    NDC51285-523
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameAntabuse
    NameDisulfiram
    Dosage FormTABLET
    RouteORAL
    On market since20001201
    LabelerTeva Women's Health, Inc.
    Active Ingredient(s)DISULFIRAM
    Strength(s)250
    Unit(s)mg/1
    Pharma ClassAcetyl Aldehyde Dehydrogenase Inhibitors [MoA],Aldehyde Dehydrogenase Inhibitor [EPC]

    More About Antabuse

    Side Effects reported to FDA: 50

    Antabuse safety alerts: No

    Reported deaths: 2

    Reported hospitalizations: 26

    Latest Antabuse clinical trials